洪志宏

職稱副院長

專長婦科腫瘤、攝護腺腫瘤、淋巴瘤、肝癌、消化系統癌症、輻射及腫瘤生物研究
學歷1984 台北醫學院醫學士畢業
1995 美國加州大學洛杉磯分校,生醫物理學博士 (Biomedical Physics) 畢業,主修輻射生物
經歷1984~1988 林口長庚醫院放射治療住院醫師訓練
1988~1990 林口長庚醫院放射治療科主治醫師
1990~1995 美國加州大學洛杉磯分校 生醫物理研究生
1995 美國加州大學洛杉磯分校醫學院射治療科博士後研究
1995~1997 林口長庚醫院放射治療科主治醫師
1995~2005 長庚大學副教授
1997~1998 長庚大學醫技系放射組組主任
1997~2014 林口長庚醫院放射腫瘤科主任
2004~ 
長庚醫院教授級主治醫師、林口長庚醫院癌症中心副主任
2005~ 長庚大學教授
2010~2012 林口長庚醫院癌症中心主任
2014~2016 台灣放射腫瘤學會理事長
2014~ 林口長庚醫院副院長


參與學會American Association of Cancer Research (AACR)
American Society for Therapeutic Radiology and Oncology (ASTRO)
Taiwan Society for Therapeutic Radiology and Oncology Chinese Society for Medical Physics
International Gynecologic Cancer Society (IGCS)
Radiation Research Society (RRS)
Radiological Society of R.O.C
發表論文

Publications (*Corresponding author)

  • S. Y. Lin, C. S. Tsai, Y. C. Chang, K. K. Ng, T. C. Chang, W. H. Kao and J. H. Hong* The role of pretreatment FDG-PET in managing cervical cancer patients with enlarged pelvic lymph node(s) shown on MRI: a phase III randomized trial with long-term follow-up. Int. J. Radiat. Oncol. Biol. Phys. 2015, Jul, 92:577-585 (SCI)
  • C. F. Yu, C. M. Lin, S.C. Wang, F. C. Chen, J. H. Hong, C. S. Tsai, Y. C. Yang and C. S. Chiang Effects of pre-irradiation and SDF-1 suppression on the progression of murine astrocytoma cells grown in different stromal beds. Int. J. Radiat. Biol. 2014, Dec, 90:1162-1168 (SCI)
  • B.S. Huang, N.M. Tsang, S.M. Lin, D. Y. Lin, J. M. Lien, C. C. Lin, W. T. Chen, W.Y. Chen, J. H. Hong* High-dose hypofractionated X-ray radiotherapy for hepatocellular carcinoma: Tumor responses and toxicities. Oncol. Lett. 2013, 6:1514-1520 (SCI)
  • F.H. Chen, S.Y. Fu, Y.C. Yang, C.C. Wang, C.S. Chiang and J. H. Hong* Combination of vessel-targeting agents and fractionated radiation therapy: the role of the SDF-1/CXCR4 pathway. Int. J. Radiat. Oncol. Biol. Phys., 2013, 86: 777-784 (SCI)
  • C. F. Yu, J. H. Hong, C. S. Chiang The roles of macrophages and nitric oxide in interleukin-3-enhanced HSV-Sr39tk-mediated prodrug therapy PLoS One, 2013, 8: e56508 (SCI)
  • J. J. Chen, S. Y. Fu, C.S. Chiang, J. H. Hong, C. K. Yeh A preclinical study to explore vasculature differences between primary and recurrent tumors using ultrasound Doppler imaging. Ultrasound Med. Biol. 2013, 39: 860-9 (SCI)
  • C. E. Wu, Y. C. Lin, J. H. Hong, C.K. Chuang, S. T. Pang, C.C. Liaw Prognostic Value of Complete Response in Patients with Muscle-invasive Bladder Cancer Undergoing Concurrent Chemoradiotherapy Anticancer Res, 2013, 33: 2605-10 (SCI)
  • D. L. Tsan, K. H. Fan, Y.C. Chen, C. K. Chuang, C. C. Lee and J.H. Hong*Pre-radiotherapy PSA level as a predictor for biochemical control in prostate cancer patients receiving radiotherapy after radical prostatectomy. Biomed J., 2013, 36:71-6
  • Y. C. Lin, J. J. Wang, J. H. Hong, Y. P. Lin, C. C. Lee, Y. Y. Wai, S. H. Ng, Y. M. Wu, C. C. Wang Noninvasive monitoring of microvascular changes with partial irradiation using dynamic contrast-enhanced and blood oxygen level-dependent magnetic resonance imaging. Int. J. Radiat. Oncol. Biol. Phys., 2013, 85:1367-74 (SCI)
  • P.F. Tsai, S. M. Lin, S. H. Lee, C. Y. Yeh, Y. T. Huang, C. C. Lee, J. H. Hong* The feasibility study of using multiple partial volumetric-modulated arcs therapy in early stage left-sided breast cancer patients. J Appl Clin Med Phys. 2012 13:3806. doi: 10.1120/jacmp.v13i5.3806. (SCI)
  • J. J. Chen, S. Y. Fu, C. S. Chiang, J. H. Hong and C. K. Yeh Characterization of tumor vasculature distribution in centeral and peripheral regions based on doppler ultrasound. Med. Phys, 2012, 39,7490-7498 (SCI)
  • C. C. Wang, C. H. Lai, Y. T. Huang, A. C. Chao, H. H. Chou and J. H. Hong* HPV genotypes predict survival benefits from concurrent chemotherapy and radiation therapy in advanced squamous cell carcinoma of the cervix. Int. J. Radiat. Oncol. Biol. Phys., 2012, 84:e499-506 (SCI)
  • C. T. Wu, C. C. Hsieh, C. C. Lin, W. C. Chen, J. H. Hong and M. F. Chen Significance of IL-6 in the transition of hormone-resistant prostate cancer and the induction of myeloid-derived suppressor cells. J Mol Med (Berl). 2012, 90:1343-55 (SCI)
  • C. S. Chiang, S. Y. Fu, S. C. Wang, C. F. Yu, F. H. Chen, C. M. Lin, J. H. Hong Irradiation promotes an m2 macrophage phenotype in tumor hypoxia. Front. Oncol. 2012, 2:89
  • Y. T. Huang, C. C. Wang, C. S. Tsai, C. H. Lai, T. C. Chang, H. H. Chou,. P. Lee and J. H. Hong* Clinical behaviors and outcomes for adenocarcinomas or adenosquamous carcinomas of cervix treated by radical surgery and adjuvant radiotherapy or chemoradiotherapy. Int. J. Radiat. Oncol. Biol. Phys., 2012, 84: 420-427 (SCI)
  • P. C. Pai, C.C. Chuang, C. K. Tseng, N. M. Tsang, K. P. Chang, T. C. Yen, C. T. Laio, J. H. Hong, J. T. Chang Impact of pretreatment body mass index on patients with head-and-neck cancer treated with radiation. Int. J. Radiat. Oncol. Biol. Phys., 2012, 83: e93-e100 (SCI)
  • K. J. Lin, C. C.Wu, Y. H. Pan, F.H. Chen, S.Y. Fu, C.S. Chiang, J.H. Hong, J.M. Lo In vivo imaging of radiation-induced tissue apoptosis by (99m)Tc(I)-his (6)-annexin A5. Ann. Nucl. Med., 2012, 26: 272-80 (SCI)
  • K. H. Fan, Y. C. Chen, W. M. Leung, C. K. Chuang, S. T. Pang and J. H. Hong*, Adjuvant and Salvage Radiotherapy for Urothelial Cell Carcinoma of Upper Urinary Tract: A Single Institute Experience. Chang Gung Med. J. 2012, 35: 247-254
  • S. C. Wang, J. H. Hong, C. Hsueh, and C. S. Chiang Tumor-secreted SDF-1 promotes glioma invasiveness and TAM tropism toward hypoxia in a murine astrocytoma model. Lab Invest. 2012, 92: 151-162 (SCI)
  • K. C. Ho, C. C. Wang, J. T. Qiu, C. H. Lai, J. H. Hong, Y. T. Huang, K. G. Huang, A. Chao, G. lin and T. C. Yen Identification of prognostic factors in patients with cervical cancer and supraclavicular lymph node recurrence, Gynecol. Oncol. 2011, 123: 253-256 (SCI)
  • F. H. Chen, C. S. Chiang, C. C. Wang, S. Y. Fu, C. S. Tsai, S. M. Jung, C. J. Wen, C. C. Lee, and J. H. Hong* Vasculatures in Tumors Growing from Preirradiated Tissues: Formed by Vasculogenesis and Resistant to Radiation and Antiangiogenic Therapy. Int. J. Radiat. Oncol. Biol. Phys., 2011, 80: 1512-1521 (SCI)
  • J. J. Chen, J, J. Jason Chen, C. S. Chiang, J. H. Hong, C. K. Yeh Assessment of tumor vasculature for diagnostic and therapeutic applications in a mouse model in vivo using 25-MHz power Doppler imaging, Ultrasonics, 2011, 51: 925-931 (SCI)
  • Y. T. Huang, C. C. Wang, C. S. Tsai, C. H. Lai, T. C. Chang, H. H. Chou, S. Hsueh, C. K. Chen, S. P. Lee and J. H. Hong* Long term outcome and prognostic factors for adenocarcinoma/adenosquamous carcinoma of cervix after definite radiotherapy. Int. J. Radiat. Oncol. Biol. Phys., 2011, 80: 429-436 (SCI)
  • S. C. Wang, C. C. Wu, Y. Y. Wei, J. H. Hong, C. S. Chiang Inactivation of ataxia telangiectasia mutated gene can increase intracellular reactive oxygen species levels and alter radiation-induced cell death pathways in human glioma cells. Int J Radiat Biol. 2011, 87:432-42 (SCI)
  • L. H. Hsu, Y. P. Chen, H. P. Chang, Y. R. Chen, J. H. Hong, A. Chao, C. H. Successful salvage treatment of recurrent endometrial cancer with multiple lung and abdominal metastases. Eur J Gynaecol Oncol. 2011;32:218-20 (SCI)
  • W. C. Cheng, M. L. Tsai, C. W. Chang, C. L. Huang, C. R. Chen, W. Y. Shu,Y. S. Lee, T. H. Wang, J. H. Hong, C. Y. Li and I. C. Hsu. Microarray meta-analysis database (M(2)DB): a uniformly pre-processed, quality controlled, and manually curated human clinical microarray database. BMC Bioinformatics. 11:421, 2010 (SCI)
  • H. H. Chou, H. P. Chang, C. H. Lai, K. K. Ng, S. Hsueh, T. I. Wu, M. Y. Chen, T. C. Yen, J. H. Hong and T. C. Chang 18F-FDG PET in stage IB/IIB cervical adenocarcinoma/adenosquamous carcinoma. Eur J Nucl Med Mol Imaging. 37: 728-735, 2010 (SCI)
  • C. C. Wang, C. H. Lai, H. J. Huang, A. Chao, C. J. Chang, T. C. Chang, H. H. Chou and J. H. Hong* Clinical Impact of Human Papillomavirus Genotypes in Patients with Cervical Cancer Undergoing Primary Radiotherapy. Int. J. Radiat. Oncol. Biol. Phys., 78: 1111-1120, 2010 (SCI)
  • C. S. Tsai, C. H. Lai, T. C. Chang, T. C. Yen, K. K. Ng, S. Hsueh, and J. H. Hong*A prospective randomized trial to study the impact of pre-treatment FDG-PET for cervical cancer patients with positive pelvic nodes but negative para-aortic node shown on MRI . Int. J. Radiat. Oncol. Biol. Phys., 76: 477-484, 2010 (SCI)
  • F. Y. Liu, T. C. Yen, M. Y. Chen, C. H. Lai, T. C. Chang, H. H. Chou, J. H. Hong, Y. R.Chen and K. K. Ng Detection of hematogenous bone metastasis in cervical cancer: 18F-fluorodeoxyglucose-positron emission tomography versus computed tomography and magnetic resonance imaging. Cancer, 115: 5470-5480, 2009 (SCI)
  • K. H. Fan, Y. C. Chen, C. K. Chuang, M. L. Hsieh and J. H. Hong*: Adjuvant androgen deprivation therapy loses its therapeutic benefit after premature termination: an experience of combined modality treatment on prostate cancer. Chang Gung Med. J. 32: 526-534, 2009
  • T. M. Huang, J. H. Hong, W. M. Leung, C. Y. Lin, D. L. Tsa and N. M. Tsang Radiation therapy for advanced hepatocellular carcinoma with hepatic hilum involvement and high bilirubin level: better survival in decreased bilirubin after radiotherapy. Therapeutic Radio. Oncol. (R. O. C.), 16: 179-194, 2009
  • D. I. Tsan, J. H. Hong, N. M. Tsang, C. H. Chen and S. Y. Lin : Treatment outcome and pattern of failure in patients with Hodgkin’s lymphoma treated with radiotherapy: a single institution’s experience. Therapeutic Radio. Oncol. (R. O. C.), 16: 85-97, 2009
  • T. C. Chao, A. M. Chen, S. J. Tu, C. J. Tung, J. H. Hong and C. C. Lee Evaluation of 6 and 18 MeV electron beams for small animal iirradiation. Phys. Med. Biol., 54: 5847-5860, 2009 (SCI)
  • M. H. Lin, T. C. Chao, C. C. Lee, C. J. Tung, C. Y. Yeh and J. H. Hong Measurement-Based Monte Carlo Dose Calculation System for IMRT Pre-treatment and In-vivo Dose Verifications. Med. Phys, 36:1167-75, 2009 (SCI)
  • F. H. Chen, C. S. Chiang, C. C. Wang, C. S. Tsai, S. M. Jung, C. C. Lee, W. H. McBride, and J. H. Hong*: Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors. Clin. Cancer Res. 15:1721-1729, 2009 (SCI)
  • W. C. Liu, W. L. Chuang, M. L. Tsai, J. H. Hong, W. H. McBride and C. S. Chiang. Cordyceps sinensis health supplement enhances recovery from Taxol-induced leucopenia. Exp. Biol. Med., 233:447-455, 2008 (SCI)
  • A. Chao , T. H. Wang, Y. S. Lee, J. H. Hong, C. N. Tsai , C. K.Chen, C. S. Tsai, A. S. Chao, C. H. Lai. Analysis of functional groups of differentially expressed genes in the peripheral blood of patients with cervical cancer undergoing concurrent chemoradiation treatment. Radiat Res. 169:76-86, 2008 (SCI)
  • C. S. Chiang, F. H. Chen, J. H. Hong, P. S. Jiang, H. L. Huang, C. C. Wang and W. H. McBride: Functional phenotype of macrophages depends on assay procedures, Int. Immunology, 20:215-22. 2008 (SCI)
  • T. C. Yen, L. C. See , C. H. Lai, C. S. Tsai, A. Chao, S. Hsueh, J. H. Hong, T. C. Chang and K. K. Ng. Standardized uptake value in para-aortic lymph nodes is a significant prognostic factor in patients with primary advanced squamous cervical cancer. Eur J Nucl Med Mol Imaging. 35:493-501, 2008 (SCI)