Page 15 - 分子轉譯影像中心季刊X

結論
到目前為止，單獨使用聚焦式超音波尚未能持續抑制腫瘤生長，研究人員正
致力於將聚焦式超音波搭配其他免疫治療藥物使用，由於聚焦式超音波能夠開啟
血腦屏障增強藥物穿透性，因此成為一種極具潛力的方式，有機會提高免疫治療

在惡性腫瘤治療中的有效性。

參考資料
1. Chabner BA. In: L. Brunton, B. Chabner and B. Knollmann eds.
Goodman and Gilman’s the Pharmacological Basis of Therapeutics.
12e ed. New York: McGraw-Hill; 2011:1-9

2. Sharkey RM and Goldenberg DM. Targeted therapy of cancer: New
prospects for antibodies and immunoconjugates. CA Cancer J Clin
2006; 56: 226-43
3. Chen DS, Mellman I. Oncology meets immunology: the cancer-
immunity cycle. Immunity 2013; 39: 1-10
4. Dong H, Strome SE, Salomao DR, et al. Tumor-associated B7-H1
promotes T-cell apoptosis: a potential mechanism of immune evasion.
Nat Med 2002; 8: 793-800
5. 免疫治療於癌症之應用
https://geneonline.news/index.php/2017/12/28/the-application-of-
immunotherapy-in-cancer-treatments/

6. The treatment of tumors with focused ultrasound can stimulate the
immune system and potentially enhance the body‘s ability to manage
cancer.
https://www.fusfoundation.org/mechanisms-of-
action/immunomodulation