Chuang Gung Medical Foundation, Division of Pediatric Allergy, Asthma and Rheumatology - UNREGISTERED VERSION

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Q:
Hello, I would like to ask your hospital children immunodeficiency screening and immune function check out what items cost much, thank you!

A:
The congenital immunodeficiency children in Taiwan incidence of about 100,000 of 2.15, is a rare disease. Immune function tests are very much, but we would check Immune function according to the clinical symptoms of the children, simply, if (1) the upper respiratory tract recurrent bacterial infections (sinusitis, otitis media), or chronic diarrhea, verify the amount of immunoglobulin and lymphocyte subpopulations, you need to add to do functional testing of the complement; (2) easy to skin infection (cellulitis).In addition to the above test, the other function detect including chemotaxis, phagocytic activity (phagocytosis) and free radical ability detect the H2O2 production (at their own expense 2000-3000NT)was need; (3) Easy fungal infection (nail fungal or oral thrush), T cell function need to be done, mainly proliferative response (2000-3000 NT).
If the family has a congenital immune deficiency, often have the following nine warning: 1. eight times a year new hair ear infections.2. serious sinus infections in the year, more than twice.3. more than two months antibiotics invalid year.4. more than twice bacterial pneumonia 5. infant weight gain or the unusual weight 6. recurrent deep skin or organ abscesses 7. 1-year-old continued to thrush.8. need intravenous antibiotics to clear the infection. 9.two deep infection .Of Allergy, Asthma Center physician can check immune function for children avoid unnecessary worries, thanks!

Q:
a baby born on November 2003,was l diagnosed of congenital immunodeficiency disease, diagnostic code: 27900 diagnostic disease name: Low agammaglobulinemia at the Taipei National Taiwan University Hospital on September 2006. After that, the baby received injection drug name: Gamimune N IV 2.5g/50 mL/vial (Iammune Globulin, Human) 4 bottles each injection at National Taiwan University Hospital
Will Chang Gung Memorial Hospital have such drugs and what can we see which doctor?

A:
we have immunoglobulin in out hospital and you can visit Dr, Wen-Yi Lee clinic.

Q:
Doctors Hello: My baby teeth from the middle of the gums grow out or gums part of the whole teeth toothy. We heard that the case was a problem in the immune system. However other dental doctor said this was not the immune system problem. I would like to ask a physician to check the child was hanging this subject? Thank you for your valuable commentary

A:
Immune disease may be the performance of many and we must do from the history and physical examination to determine the initial doubt to arrange further examination. Our doctor Wen-Yi Lee specializes in immunodeficiency, you are welcome to bring their children to the clinic for further discussion to physicians. Thanks!

Q:
Hello physician: Would like to ask whether the Favism with atopic dermatitis related to the presence! Two kinds of illnesses was noted in my child, and the child are very vulnerable to cold and also very easy to otitis media. I do not know how to prevent or how to resolve?

A:
1 Favism with atopic dermatitis is not associated.
2. Colds and easy to otitis media, must first rule out allergies (allergic wake up in the morning easy to sneezing, runny nose, itchy eyes, night cough, especially when the weather changes. Vulnerable to cold episodes of confusion often associated with allergies, to distinguish between a cold or allergy attack can refer to the center of health education articles. http://www.cgmh.org.tw/chldhos/intr/c4a80/06index003-1.htm


Q:
Hello, I would like to ask the center whether the diagnosis and treatment of chronic granulomatous patients?
A:
Hello family members:
According to the papers published in Immunobiology journal by the 2011 undergraduate Wen-Yi Lee MD. Overall incidence of all congenital immunodeficiency disease was per 100,000 of 2.17 person in Taiwan from 1985-2010,and chronic granulomatous was part of them. It can be seen the disease is rare diseases. We have also accumulated a lot of this disease clinical research and treatment experience. Currently in addition to the case of prenatal diagnosis, the stable outpatient follow the treatment of patients, and stem cell transplantation in the treatment of cases were also success in our hospital.

Reference:
Distribution, clinical features and treatment in Taiwanese patients with symptomatic primary immunodeficiency diseases (PIDs) in a nationwide population-based study during 1985–2010
Wen-I Lee, Jing-Long Huang, et al., Immunobiology 216 (2011) 1286– 1294

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