• 期刊發表(2016年)

  1. Wang HM, Cheng NM, Lee LY, Fang YH, Chang TC, Tsan DL, Ng SH, Liao CT, Yang LY, Yen TC*. Heterogeneity of 18F-FDG PET combined with expression of EGFR may improve the prognostic stratification of advanced oropharyngeal carcinoma Int J Cancer 2016;138:731-8. (SCI=5.531)(29/213=13.6%) Link

  2. Tsang NM, Pai PC, Chuang CC, Chuang WC, Tseng CK, Chang KP, Yen TC, Lin J, Chang JT. Overweight and obesity predict better overall survival rates in cancer patients with distant metastases. Cancer Med 2016;5(4):665-75 (SCI=2.915)(107/213=50.2%)Link

  3. Wu KY, Liu CY, Chen CS, Chen CH, Hsiao IT, Hsieh CJ, Lee CP, Yen TC, Lin KJ. Beta-amyloid deposition and cognitive function in patients with major depressive disorder with different subtypes of mild cognitive impairment: 18F-florbetapir (AV-45/Amyvid) PET study. Eur J Nucl Med Mol I 2016;43(6):1067-76 (SCI=5.537)(6/124=4.83%) Link

  4. Fang TJ, Lin WN, Lee LY, Young CK, Lee LA, Chang KP, Liao CT, Li HY, Yen TC. Classification of vocal fold leukoplakia by clinical scoring Head Neck 2016;38 Suppl 1:E1998-2003 (SCI=2.76)(3/43=6.9%) Link

  5. Liao CT, Kang CJ, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Ng SH, Lin CH, Tsao CK, Fang TJ, Huang SF, Chang KP, Chang YL, Yang LY, Yen TC*. Association between multidisciplinary team care approach and survival rates in patients with oral cavity squamous cell carcinoma Head Neck 2016;38 Suppl 1:E1544-53 (SCI=2.76) (3/43=6.9%) Link

  6. Ng SH, Liao CT, Lin CY, Chan SC, Lin YC, Yen TC, Chang JT, Ko SF, Fan KH, Wang HM, Yang LY, Wang JJ. Dynamic contrast-enhanced MRI, diffusion-weighted MRI and 18F-FDG PET/CT for the prediction of survival in oropharyngeal or hypopharyngeal squamous cell carcinoma treated with chemoradiation Eur Radiol 2016;24. [Epub ahead of print] (SCI=3.64)(18/124=14.5%) Link

  7. Chen SH, Wang HM, Lin CY, Chang JT, Hsieh CH, Liao CT, Kang CJ, Yang LY, Yen TC*. RGD-K5 PET/CT in patients with advanced head and neck cancer treated with concurrent chemoradiotherapy: Results from a pilot study Eur J Nucl Med Mol I 2016;43:1621-9 (SCI=5.537) (6/124=4.83%) Link

  8. Cheng NM, Fang YH, Tsan DL, Hsu CH, Yen TC*. Respiration-averaged CT for attenuation correction of PET images - impact on PET texture features in Non-small cell lung cancer patients PLoS One 2016;11:e0150509 (SCI=3.057)(11/63=17.4%) Link

  9. Liao CT, Chen SJ, Lee LY, Hsueh C, Yang LY, Lin CY, Fan KH, Wang HM, Ng SH, Lin CH, Tsao CK, Chen IH, Chang KP, Huang SF, Kang CJ, Chen HC, Yen TC*. An Ultra-Deep targeted sequencing gene panel improves the prognostic stratification of patients with advanced oral cavity squamous cell carcinoma. Medicine 2016;95:e2751 (SCI=1.206)(40/155=25.8%) Link

  10. Hsieh CE, Lin CY, Lee LY, Yang LY, Wang CC, Wang HM, Chang JT, Fan KH, Liao CT, Yen TC, Fang KH, Tsang YM. Adding concurrent chemotherapy to postoperative radiotherapy improves locoregional control but Not overall survival in patients with salivary gland adenoid cystic carcinoma-a propensity score matched study Radiat Oncol 2016;22;11(1):47 (SCI=2.466)(43/124=34.6%)Link

  11. Lin KJ, Hsiao IT, Hsu JL, Huang CC, Huang KL, Hsieh CJ, Wey SP, Yen TC. Imaging characteristic of dual-phase 18F-florbetapir (AV-45/Amyvid) PET for the concomitant detection of perfusion deficits and beta-amyloid deposition in Alzheimer's disease and mild cognitive impairment Eur J Nucl Med Mol I 2016;43:1304-14 (SCI=5.537) (6/124=4.83%) Link

  12. Adel M, Liao CT, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Ng SH, Lin CH, Tsao CK, Huang SF, Kang CJ, Fang KH, Wang YC, Chang KP, Fang TJ, Yang LY, Yen TC*. Incidence and outcomes of patients with oral cavity squamous cell carcinoma and fourth primary tumors: A long-term follow-up study in a betel quid chewing endemic area Medicine 2016;95(12):e2950 (SCI=1.206) (40/155=25.8%) Link

  13. Chang IC, Huang SF, Chen PJ, Chen CL, Chen CL, Wu CC, Tsai CC, Lee PH, Chen MF, Lee CM, Yu HC, Lo GH, Yeh CT, Hong CC, Eng HL, Wang J, Tseng HH, Hsiao CH, Wu HD, Yen TC, Liaw YF. The Hepatitis Viral Status in Patients With Hepatocellular Carcinoma: a Study of 3843 Patients From Taiwan Liver Cancer Network Medicine 2016;95(15):e3284 (SCI=1.206) (40/155=25.8%) Link

  14. Wang HM, Lin CY, Hsieh CH, Hsu CL, Fan KH, Chang JT, Huang SF, Kang CJ, Liao CT, Ng SH, Yen TC*. Induction chemotherapy with dose-modified docetaxel, cisplatin, and 5-fluorouracil in Asian patients with borderline resectable or unresectable head and neck cancer J Formos Med Assoc 2016;25. pii: S0929-6646(16)30015-8 (SCI=2.018)(29.6%) Link

  15. Liu FY, Lai CH, Yang LY, Wang CC, Lin G, Chang CJ, Chang WY, Huang SH, Huang YE, Peng NJ, Hong JH, Chao A, Chou HH, Chang YC, Yen TC*. Utility of 18F-FDG PET/CT in patients with advanced squamous cell carcinoma of the uterine cervix receiving concurrent chemoradiotherapy: a parallel study of a prospective randomized trial Eur J Nucl Med Mol I 2016;43:1812-23 (SCI=5.537) (6/124=4.83%) Link

  16. Ho KC, Fang YD, Chung HW, Liu YC, Chang JW, Hou MM, Yang CT, Cheng NM, Su TP, Yen TC*. TLG-S criteria are superior to both EORTC and PERCIST for predicting outcomes in patients with metastatic lung adenocarcinoma treated with erlotinib. Eur J Nucl Med Mol I 2016 Jun 3. [Epub ahead of print] (SCI=5.537) (6/124=4.83%) Link

  17. Lapke N, Lu YJ, Liao CT, Lee LY, Lin CY, Wang HM, Ng SH, Chen SJ, Yen TC* Missense mutations in the TP53 DNA-binding domain predict outcomes in patients with advanced oral cavity squamous cell carcinoma. Oncotarget 2016 Jun 8. doi: 10.18632 (SCI=5.008)(36/213=16.9%) Link

  18. Lin G, Lai CH, Tsai SY, Lin YC, Huang YT, Wu RC, Yang LY, Lu HY, Chao A, Wang CC, Ng KK, Ng SH, Chou HH, Yen TC, Hung JH 1 H MR spectroscopy in cervical carcinoma using external phase array body coil at 3.0 Tesla: Prediction of poor prognostic human papillomavirus genotypes J Magn Reson Imaging 2016 Jul 19. doi: 10.1002/jmri.25386. [Epub ahead of print] (SCI=3.25)(23/124=18.5%) Link

  19. Chan SC, Chang KP, Fang YD, Tsang NM, Ng SH, Hsu CL, Liao CT, Yen TC Tumor heterogeneity measured on F-18 fluorodeoxyglucose positron emission tomography/computed tomography combined with plasma Epstein-Barr Virus load predicts prognosis in patients with primary nasopharyngeal carcinoma Laryngoscope 2016 Jul 20. doi: 10.1002/lary.26172. [Epub ahead of print] (SCI=2.272)(9/43=20.9%) Link

  20. Ho KC, Fang YH, Chung HW, Yen TC, Ho TY, Chou HH, Hong JH, Huang YT, Wang CC, Lai CH A preliminary investigation into textural features of intratumoral metabolic heterogeneity in (18)F-FDG PET for overall survival prognosis in patients with bulky cervical cancer treated with definitive concurrent chemoradiotherapy Am J Nucl Med Mol Imaging 2016; 6:166-75 Link

  21. Su YY, Chen SS, Hsieh CH, Liao CT, Lin CY, Kang CJ, Yen TC* Defining risk groups of patients with cancer of unknown primary site and cervical nodal metastases by F-18 fluorodeoxyglucose positron emission tomography and computed tomography imaging Kaohsiung J Med Sci 2016;32:407-13 (SCI=1)(104/124=83.8%) Link

  22. Wang HM, Liao CT, Yen TC, Chen SJ, Lee LY, Hsieh CH, Lin CY, Ng SH Clues toward precision medicine in oral squamous cell carcinoma: utility of next-generation sequencing for the prognostic stratification of high-risk patients harboring neck lymph node extracapsular extension Oncotarget 2016 Aug 31. doi: 10.18632/oncotarget.11762. [Epub ahead of print] (SCI=5.008) (36/213=16.9%) Link

  23. Yi-Hsin Weng?, Chu-Yu Chen?, Kun-Jun Lin , Ying-Ling Chen, Tu-Hsueh Yeh, Ing-Tsung Hsiao, Ing-Jou Chen, Chin-Song Lu, Hung-Li Wang*. (R1441C) LRRK2 induces the degeneration of SN dopaminergic neurons and alters the expression of genes regulating neuronal survival in a transgenic mouse model. Experimental Neurology. 2016 January; 275(1):104-115. (SCI=4.657 ， 51/256=19.9%) Link

  24. Ming-Fan Chung, Hung-Yi Liu, Kun-Ju Lin, Wei-Tso Chia,* and Hsing-Wen Sung*. A pH-Responsive Carrier System that Generates NO Bubbles to Trigger Drug Release and Reverse P-Glycoprotein-Mediated Multidrug Resistance**. Angewandte Chemie International Edition, Volume 54, Issue 34, August 17, 2015 , Pages 9890–9893 Link

  25. Pan WY, Lin KJ, Huang CC, Chiang WL, Lin YJ, Lin WC, Chuang EY, Chang Y, Sung HW* . Localized sequence-specific release of a chemopreventive agent and an anticancer drug in a time-controllable manner to enhance therapeutic efficacy. Biomaterials , vol. 101, pp. 241–250, 2016. (SCI=8.387) correspondence 2/76=2.6% Link

  26. Chuang EY, Lin CC, Chen KJ, Wan DH, Lin KJ, Ho YC, Lin PY, Sung HW* . A FRET-guided, NIR-responsive bubble-generating liposomal system for in vivo targeted therapy with spatially and temporally precise controlled release. Biomaterials , vol. 93, pp. 48–59, 2016. (SCI=8.387) correspondence 2/76=2.6% Link

  27. Huang CC, Chia WT, Chung MF, Lin KJ, Hsiao CW, Jin C, Lim WH, Chen CC, Sung HW* . An implantable depot that can generate oxygen in situ for overcoming hypoxia-induced resistance to anticancer drugs in chemotherapy. Journal of the American Chmical Society , vol. 138, pp. 5222–5225, 2016. (SCI=13.038) correspondence 10/163=6.1% Link

  28. Huang CC Pan WY, Tseng MT, Lin KJ, Yang YP, Tsai HW, Hwang SM, Chang Y, Wei HJ, Sung HW* . Enhancement of cell adhesion, retention, and survival of HUVEC/cbMSC aggregates that are transplanted in ischemic tissues by concurrent delivery of an antioxidant for therapeutic angiogenesis. Biomaterials , vol. 74, pp. 53–63, 2016. (SCI=8.387) correspondence 2/76=2.6% Link

  29. Huang CC, Wei HJ, Lin KJ, Lin WW, Wang CW, Pan WY, Hwang SM, Chang Y, Sung HW* . Multimodality noninvasive imaging for assessing therapeutic effects of exogenously transplanted cell aggregates capable of angiogenesis on acute myocardial infarction. Biomaterials , vol. 73, pp. 12–22, 2015. 2015. (SCI=8.387) correspondence 2/76=2.6% Link

  30. Chuang EY, Lin KJ, Lin PY, Chen HL, Wey SP, Mi FL, Hsiao HC, Chen CT, Sung HW* . Self-assembling bubble carriers for oral protein delivery. Biomaterials , vol. 64, pp. 115–124, 2015. (SCI=8.387) correspondence 2/76=2.6% Link

  31. Chung MF, Liu HY, Lin KJ, Chia WT, Sung HW* . A pH-responsive carrier system that generates NO bubbles to trigger drug release and reverse P-glycoprotein-mediated multidrug resistance. Angewandte Chemie International Edition , vol. 54, pp. 9890–9893, 2015. (SCI=11.709) correspondence 11/163=6.7% Link

  32. Hsiao CW, Chuang EY, Chen HL, Wan DH, Korupalli C, Liao ZX, Chiu YL, Chia WT, Lin KJ, Sung HW* . Photothermal tumor ablation in mice with repeated therapy sessions using NIR-absorbing micellar hydrogels formed in situ . Biomaterials , vol. 56, pp. 26–35, 2015. (SCI=8.387) correspondence 2/76=2.6% Link

  33. Liao ZX, Chuang EY, Lin CC, Ho YC, Lin KJ, Cheng PY, Chen KJ, Wei HJ, Sung HW* . An AS1411 aptamer-conjugated liposomal system containing a bubble-generating agent for tumor-specific chemotherapy that overcomes multidrug resistance. Journal of Controlled Release , vol. 208, pp.42 － 51, 2015. (SCI=7.441) correspondence 9/255=3.5% Link

  34. Chin-Yu Lin, Yao-Horng Wang , Kuei-Chang Li, Li-Yu Sung, Chia-Lin Yeh, Kun-Ju Lin, Tzu-Chen Yen, Yu-Han Chang **, Yu-Chen Hu, * Healing of massive segmental femoral bone defects in minipigs by allogenic ASCs engineered with FLPo/Frt-based baculovirus vectors. Biomaterials 50 (2015) 98-106(SCI=8.387) 2/76=2.6% Link

  35. Ying-Cheng Huang1, Ho-Lien Huang, Chun-Nan Yeh, Kun-Ju Lin, Chung-Shan Yu. Investigation of brain tumors using 18F-fluorobutyl ethacrynic amide and its metabolite with positron emission tomography. Oncotargets and Therapy 2015:8 1877–1885. (SCI=5.008) (36/213=16.9%) Link

  36. Chu PC, Chai WY, Tsai CH, Kang ST, Yeh CK and Liu HL *, “Focused Ultrasound-Induced Blood-Brain Barrier Opening: Association with Mechanical Index and Cavitation Index Analyzed by Dynamic Contrast-Enhanced Magnetic-Resonance Imaging,” Scientific Reports , 6:33264, doi: 10.1038/srep33264, 2016 (SCI =5.228) correspondence 7/63 = 21/211=11.11%. Link

  37. Xia J, Tsui PH, Liu HL* , “Low-Pressure Burst-Mode Focused Ultrasound Wave Reconstruction and Mapping for Blood-Brain Barrier Opening: A Preclinical Examination,” Scientific Reports , 6:27939, doi:10.1038/srep27939., 2016 (SCI = 5.228), correspondence 7/63 = 21/211=11.11%. Link

  38. Lin CY, Hsieh HY, Chen CM, Wu SR, Tsai CH, Huang CY, Hua MY, Wei KC, Yeh CK, and Liu HL *, "Non-invasive, Neuron-Specific Gene Therapy by Focused Ultrasound-Induced Blood-Brain Barrier Opening in Parkinson's Disease Mouse Model", Journal of Controlled Release , Vol. 235, pp. 72-81, 2016 (SCI = 7.441) correspondence 9/253 = 3.55% . Link

  39. Fan CH, Cheng YH, Ting CY, Ho YJ, Hsu PH, Liu HL *, Yeh CK*, “Ultrasound/Magnetic Targeting with SPIO-DOX-Microbubble Complex for Image-Guided Drug Delivery in Brain Tumors,” Theranostics , Vol. 6, No. 10, pp.1542-1556, 2016 (SCI=8.854), 9/124 correspondence 9/124 = 7.25%. Link

  40. Liu HL , Hsu PH, Lin CY, Huang CW, Chai WY, Chu PC, Huang CY, Chen PY, Yang LY, Kuo JS, Wei KC *, “Focused Ultrasound Enhances CNS Delivery of Bevacizumab for Malignant Glioma Treatment,” Radiology , 18:152444, 2016 ( SCI=6.798) 2/124 = 1.61% . Link

  41. Fan CH, Ting CY, Lin CY, Chan HL, Chang YC, Chen YY, Liu HL* , and Yeh CK *, “Noninvasive, Targeted, and Non-Viral Ultrasound-Mediated GDNF-Plasmid Delivery for Treatment of Parkinson's Disease,” Scientific Reports , 6:19579. doi:10.1038/srep19579, 2016 (SCI=5.228) correspondence 7/63 = 21/211=11.11%. Link

  42. Ng SH , Liao CT, Lin CY, Chan SC, Lin YC, Yen TC, Chang JTC, Ko SF, Fan KH, Wang HM, Yang LY, Wang JJ*. Dynamic contrast-enhanced MRI, diffusion-weighted MRI, and 18F-FDG PET/CT for the prediction of survival in oropharyngeal or hypopharyngeal squamous cell carcinoma treated with chemoradiation. Eur Radiol 26 (11): 4162-4172, 2016 (Nov). (SCI=3.64)(18/124=14.5%) Link

  43. Lu CS,  Ng SH  (Contributed equally to the first author), Weng YH, Cheng JS, Lin WW, Wai YY, Chen YL, Wang JJ*. Alterations of diffusion tensor MRI parameters in the brains of patients with Parkinson's disease compared with normal brains: possible diagnostic use. Eur Radiol 26 (11): 3978-3988, 2016 (Nov). (SCI=3.64) (18/124=14.5%) Link

  44. Lu CS,  Ng SH  (Contributed equally to the first author), Lai SC, Kao LY, Liu L, Lin WY, Wu YM, Chen YL, Wang JJ*. Cortical damage in the posterior visual pathway in patients with sialidosis type1. Brain Imaging Behav. 2016 Feb [Epub ahead of print]. (SCI=3.667)(4/14=28.5%) Link

  45. Liao PA, Lin G(Contributed equally to the first author), Tsai SY, Wang CH, Juan YH, Lin YC, Wu MT, Yang LY, Liu MH, Chang TC, Lin YC, Huang YC, Huang PC, Wang JJ,  Ng SH   (corresponding author) , Ng KK*. Myocardial triglyceride content at 3 T cardiovascular magnetic resonance and left ventricular systolic function: a cross-sectional study in patients hospitalized with acute heart failure. J Cardiovasc Magn Reson 18(1):9, 2016 (Feb). (SCI=5.752)(5/124=4.03%) Link

  46. Lin G, Huang YT, Chao A, Ng KK, Yang LY,  Ng SH   (corresponding author) .   Influence of menopausal status on diagnostic accuracy of myometrial invasion in endometrial cancer: diffusion-weighted and dynamic contrast-enhanced MRI at 3 T. Clin Radiol 70: 1260-1268, 2015 (Nov) (SCI=2.151)(50/124=40.3%) Link

  47. Wu CM, Lee LA, Chen CK, Chan KC, Tsou YT,   Ng SH   (corresponding author) .   Impact of cochlear nerve deficiency determined using 3-dimensional magnetic resonance imaging on hearing outcome in children with cochlear implants.  Otol Neurotol 36(1); 14-21, 2015 (Jan) (SCI=1.953)(13/43=30.2%) Link

  48. Fang-Hsin Che n,* Chun-Chieh Wang, * Ho-Ling Li u, Sheng-Yung Fu, Ching-Fang Yu, Chen Chang, Chi-Shiun Chiang, and Ji-Hong Hong. Decline of Tumor Vascular Function as Assessed by Dynamic Contrast-Enhanced Magnetic Resonance Imaging Is Associated With Poor Responses to Radiation Therapy and Chemotherapy. International Journal of Radiation Oncology Biology Physics. Volume 95, Issue 5, 1 August 2016, Pages 1495–1503(SCI=4.495)(12/124=9.67%) Link

  49. Lin JY, Lai PL (co-first author) , Lin YK, Peng S, Lee LY, Chen CN and Chu IM*: A poloxamer-polypeptide thermosensitive hydrogel as a cell sca ff old and sustained release depot. Polymer Chemistry . 2016 Mar 29; Vol.7:2976-2985. (SCI ； IF= 5.52 ； Polymer Science 6/82=7.32%) Link

  50. Liu T-Y, Huang T-K, Yang S-Y, Hong Y-T, Huang S-M, Wang F-N, Chiang S-F, Tsai S-Y, Lu W-C, Chiou T-J* (2016) Identification of plant vacuolar transporters mediating phosphate storage. Nat Commun 7: 11095 (IF: 11.329 ； Raking: 3/61=4.9% in MULTIDISCIPLINARY SCIENCES) Link

  51. Huang SM, Wu YL, Peng SL, Peng HH, Huang TY, Ho KC, *Wang FN . ” Inter-Strain Differences in Default Mode Network: A Resting State fMRI Study on Spontaneously Hypertensive Rat and Wistar Kyoto Rat.” Sci Rep. 2016 Feb 22; 6:21697. (SCI=5.228) c orrespondence 7/63=11.1% in MULTIDISCIPLINARY SCIENCES Link

  52. Chen MH 1 , Weng JJ 2 , Cheng CT 3 , Wu RC 4 , Huang SC 4 , Wu CE 5 , Chung YH 6 , Liu CY 1 , Chang MH 1 , Chen MH 7 , Chiang KC 8 , Yeh TS 3 , Su Y 9 , Yeh CN 10 . ALDH1A3, the Major Aldehyde Dehydrogenase Isoform in Human Cholangiocarcinoma Cells, Affects Prognosis and Gemcitabine Resistance in Cholangiocarcinoma Patients. Clin Cancer Res. 2016 Apr 13. [Epub ahead of print](SCI:8.738 12/213=5.63%) Link

  53. Chen MH, Yen CC, Cheng CT, Wu RC, Huang SC, Yu CS, Chung YH, Liu CY, Chang PM, Chao Y, Chen MH, Chen YF, Chiang KC, Yeh TS, Chen TC, Huang CY, Yeh CN. Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. Oncotarget. 2015 Sep 15;6(27):23594-608. (SCI=5.008)(36/213=16.9%) Link

  54. Chen MH, Yen CC, Cheng CT, Wu RC, Huang SC, Yu CS, Chung YH, Liu CY, Chang PM, Chao Y, Chen MH, Chen YF, Chiang KC, Yeh TS, Chen TC, Huang CY*, Yeh CN *. Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. Oncotarget. 2015 Sep 15;6(27):23594-608. (SCI=5.008) correspondence 36/213=16.67% Link