• 期刊發表(2011年)

  1. Kang CJ, Liao CT, Hsueh C, Lee LY, Lin CY, Fan KH, Wang HM, Huang SF, Chen IH, Ng SH, Tsao CK, Huang YC, Yen TC* . Outcome analysis of patients with well-differentiated oral cavity squamous cell carcinoma. Oral Oncol. 2011 Accepted (SCI=2.871,78/184,42.4%)

  2. Kang CJ, Lin CY, Wang HM, Fan KH, Ng SH, Lee LY, Chen IH, Huang SF, Liao CT , Yen TC* . The Number of Pathologically Positive Lymph Nodes and Pathological Tumor Depth Predicts Prognosis in Patients with Poorly Differentiated Squamous Cell Carcinoma of the Oral Cavity. Int J Radiat Oncol. 2011 Jun 1. [Epub ahead of print] (SCI=4.503,10/111,9%)

  3. Liao CT, Wang HM, Huang SF, Chen IH, Kang CJ, Lin CY, Fan KH, Ng SH, Hsueh C, Lee LY, Lin CH, Yen TC* . PET and PET/CT of the Neck Lymph Nodes Improves Risk Prediction in Patients with Squamous Cell Carcinoma of the Oral Cavity. J Nucl Med . 2011;52:180-7. (SCI=7.022, 1/111, 0.9%)

  4. Gaber Y Abd El-Hafez, Chen CC, Ng SH, Lin CY, Wang HM, Chan SC, Chen IH, Huan SF, Kang CJ, Lee LY, Lin CH, Liao CT, Yen TC* . Comparison of PET/CT and MRI for the detection of bone marrow invasion in patients with squamous cell carcinoma of the oral cavity. Oral Oncol. 2011;47:288-95. (SCI=2.871,78/184,42.4%)

  5. Liu FY, Liao CT , Yen TC* . Synchronous Malignancies in Patients with Squamous Cell Carcinomas of the Oral Cavity. Eur J Nucl Med Mol I. 2011;38:1020-1028 . (SCI=5.036, 6/111, 5.4%) correspondence

  6. Liao CT, Lin CY, Fan KH, Huang SF, Chen IH, Kang CJ, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Yen TC* . Identification of a High-Risk Subgroup of Patients with Resected pT3 Oral Cavity Cancer in Need of Postoperative Adjuvant Therapy. Ann Surg Oncol. 2011 Mar 1. [Epub ahead of print] (SCI=4.182, 49/184,26.6%) correspondence

  7. Chang KP, Tsang NM , Liao CT , Hsu CL, Chung MJ, Lo CW, Chan SC , Ng SH, Wang HM, Yen TC . Prognostic significance of 18F -FDG PET parameters and plasma EBV DNA load in patients with nasopharyngeal carcinoma. J Nucl Med. Accepted. 2011. (SCI=7.022, 1/111, 0.9%)

  8. Chang KP, Chang YT, Liao CT, Yen TC , Chen IH, Chang YL, Liu YL, Chang YS, Yu JS, Wu CC. Prognostic cytokine markers in peripheral blood for oral cavity squamous cell carcinoma identified by multiplexed immunobead-based profiling. Clin Chim Acta. 2011;412:980-7. (SCI=2.388, 6/30, 20%)

  9. Ng SH, Chan SC, Yen TC , Liao CT, Lin CY, Chang JT, Ko SF, Wang HM, Chang KP, Fan KH. ET/CT and 3-T whole-body MRI in the detection of malignancy in treated oropharyngeal and hypopharyngeal carcinomas. Eur J Nucl Med Mol I. 2011;38:996-1008. (SCI=5.036, 6/111, 5.4%)

  10. Chen YJ, Liao CT, Chen PJ, Lee LY, Li YC, Chen IH, Wang HM, Chang JTC, Chen LJ, Yen TC , Tang CY, Cheng AJ*. Down-regulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract. Head Neck-J Sci Spec. 2011;33:257-66. (SCI=2.182, 5/41, 12.2%)

  11.   Chan SC, Wang HM, Yen TC , Lin CY, Chin SC, Liao CT, Wai YY, Wang JJ, Ng SH. (18)F-FDG PET/CT and 3.0-T whole-body MRI for the detection of distant metastases and second primary tumours in patients with untreated oropharyngeal/hypopharyngeal carcinoma: a comparative study. Eur J Nucl Med Mol. 2011;38:1607-19. (SCI=5.036, 6/111, 5.4%)

  12. Ho KC, Wang CC, Qiu JT, Lai CH, Hong JH, Huang YT, Huang KG, Chao A, Lin G, Yen TC* . Identification of prognostic factors in patients with cervical cancer and supraclavicular lymph node recurrence. Gynecol Oncol. 2011 Jul 30. [Epub ahead of print] (SCI=3.76, 4/75, 5.3%) correspondence

  13. Wu TI, Yen TC , Lai CH. Clinical presentation and diagnosis of uterine sarcoma,including imaging. Best Pract Res Clin Obstet Gynaecol. 2011 Aug 3. [Epub ahead of print]

  14. Lin YC, Lin G, Chen YR, Yen TC , Wang CC, Ng KK. Role of Magnetic Resonance Imaging and Apparent Diffusion Coefficient at 3T in Distinguishing between Adenocarcinoma of the Uterine Cervix and Endometrium. Chang Gung Med J. 2011;34:93-100.

  15. Wang TC, Hsiao IT, Cheng YK , Wey SP, Yen TC, Lin KJ . Noninvasive monitoring of tumor growth in a rat glioma model: comparison between neurological assessment and animal imaging. J Neuro-oncol. 2011 Feb 12. [Epub ahead of print] (SCI=2.929, 59/185, 31.9%)

  16. Ho TY, Liou MJ, Lin KJ, Yen TC* . Erratum to: Prevalence and significance of thyroid uptake detected by (18)F-FDG PET. Endocrine. 2011 May 6. [Epub ahead of print] (SCI=1.373, 98/116, 84.5%)

  17. Yang HW, Hua MY, Liu HL, Huang CY, Tsai RY, Lu YJ, Chen JY, Tang HJ, Hsien HY, Chang YS, Yen TC , Chen PY, Wei KC. Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas. Biomaterials. 2011;32:6523-32. (SCI=7.882, 2/69, 2.9%)

  18. Lu PL, Chen YC, Ou TW, Chen HH, Tsai HC, Wen CJ, Lo CL, Wey SP, Lin KJ, Yen TC* , Hsiue GH. Multifunctional hollow nanoparticles based on graft-diblock copolymers for doxorubicin delivery. Biomaterials. 2011;32:2213-21. (SCI=7.882, 2/69, 2.9%) co-correspondence

  19. Lin CY, Lin KJ, Kao CY, Chen MC, Lo WH, Yen TC , Chang YH, Hu YC. The role of adipose-derived stem cells engineered with the persistently expressing hybrid baculovirus in the healing of massive bone defects. Biomaterials. 2011;32:6505-14. (SCI=7.882, 2/69, 2.9%)

  20. Nguyen HN, Wey SP, Juang JH, Sonaje K, Ho YC, Chuang EY, Hsu CW, Yen TC , Lin KJ, Sung HW. The glucose-lowering potential of exendin-4 orally delivered via a pH-sensitive nanoparticle vehicle and effects on subsequent insulin secretion in vivo. Biomaterials. 2011;32:2673-82. (SCI=7.882, 2/69, 2.9%)

  21. Shen CR , Juang JH, Tsai ZT, Wu ST, Tsai FY, Wang JJ, Liu CL, Yen TC. Preparation, characterization and application of superparamagnetic iron oxide encapsulated with N-[(2-hydroxy-3-trimethylammonium) propyl] chitosan chloride. Carbohydrate Polymers . 2011; 84:781-7. (SCI=3.463, 3/70, 4.3%)

  22. Shen CR , Wu ST , Tsai ZT, Wang JJ, Yen TC, Tsai JS, Shih MF, Liu CL. Characterization of quaternized chitosan-stabilized iron oxide nanoparticles as a novel potential magnetic resonance imaging contrast agent for cell tracking. Polym. Int. . 2011;60:945-50. (SCI=2.056, 21/79, 26.6%)

  23.   Hua MY **, Yang HW **, Liu HL **, Tsai RY, Pang ST, Chuang KL, Chang YS, Hwang TL, Chang YH, Chuang HC, Chuang CK. Superhigh-magnetization nanocarrier as a doxorubicin delivery platform for magnetic targeting therapy. Biomaterials , 2011;32: 8999-9910 (SCI=7.882, 2/69, 2.9%)

  24. Liu HL , Chen PY, Yang HW, Wu JS, Tseng IC, Ma YJ, Huang CY, Tsai HC, Chen SM, Lu YJ, Huang CY, Hua MY, Ma YH, Yen TC, Wei KC. In Vivo MR Quantification of Superparamagnetic Iron Oxide Nanoparticle Leakage During Low-frequency-ultrasound–induced Blood–Brain Barrier Opening In Swine. Journal of Magnetic Resonance Imaging . Accepted, 2011. (SCI=2.77, 37/111, 33.3%)

  25. Yang HW, Hua MY, Liu HL **, Huang CY, Tsai RY, Lu YJ, Chen JY, Tang HJ, Hsien HY, Chang YS, Yen TC, Chen PY, Wei KC. Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas. Biomaterials . 2011;32:6523-6532. (SCI=7.882, 2/69, 2.9%)

  26.   Liu HL , Li ML, Tsui PH, Lin MS, Huang SM, Bai J. An Unified Approach to Combine Temperature Estimation and Elastography for Thermal Lesion Determination in Focused Ultrasound Thermal Therapy. Physics in Medicine and Biology . 2011;56:169-186. (SCI=3.056, 11/69, 15.9%)

  27.   Hua MY, Liu H-L ** , Yang HW, Chen PY, Tsai RY, Huang CY, Tseng IC, Lyu LA, Ma CC, Tang HJ, Yen TC, Wei KC. The effectiveness of a magnetic-nanoparticle-based delivery system for BCNU in the treatment of gliomas, Biomaterials . 2011;32:512-523. (SCI=7.882, 2/69, 2.9%)

  28.   Liao MH, Jan TR, Chiang CC, Yen KC, Liao TZ, Chen MW, Chi CW, *Wun TC, Yen TC, * Wey SP . Investigation of a potential scintigraphic tracer for imaging apoptosis: radioiodinated annexin V-Kunitz protease inhibitor fusion protein. J Biomed Biotechnol 2011;2011:675701. Epub 2011 Apr 27. (SCI=1.225, 73/106, 68.9%)

  29.   Lin KJ, Lin WY, Hsieh CJ, Weng YH, Wey SP , Lu CS, Skovronsky D, Yen TC, Chang CJ, Kung MP, Hsiao IT. Optimal scanning time window for 18 F -FP-(+)-DTBZ ( 18 F -AV-133) summed uptake measurements. Nucl Med Biol 2011 Aug 8. [Epub ahead of print] (SCI=2.620, 38/111, 34.2%)

  30. Sonaje K, Lin KJ, Tseng MT , Wey SP , Su FY, Chuang EY, Hsu CW, Chen CT , Sung HW. Effects of chitosan-nanoparticle-mediated tight junction opening on the oral absorption of endotoxins. Biomaterials 2011 Aug 19. [Epub ahead of print] (SCI=7.882, 2/69, 2.9%)

  31. Tsao HH, Skovronsky M. Daniel, Lin KJ, Yen TC, Wey SP, Kung MP. Sigma receptor binding of tetrabenazine series tracers targeting VMAT 2 in rat pancreas. Nucl Med Biol 2011 June. [Epub ahead of print] (SCI=2.620, 38/111, 34.2%)

  32. Tsai YJ, Fan Dean, Hsiao IT. Accelerating MAP reconstructions using a power factor. Submitted to Phys. Med. Bio. (SCI=3.056, 11/69, 15.9%)

  33.   Wang JJ , Lin W Y, Lu C S, Weng Y H, Ng S H, Wang C H, Liu H L, Hsieh R H, Wan Y L, Wai Y Y*. Diagnostic Utility of Diffusion Kurtosis Imaging in Parkinson's Disease. RADIOLOGY. 2011;260(3). (SCI=6.066, 2/111, 1.8%)

  34.   Wu M C, Lin Y C, Shieh C C, Wan Y L, Yen T H, Ng K K, Wai Y Y, Wang J J * . Measuring Anisotropic Diffusion in Kidney Using MRI. ACAD RADIOL . 2011;18(9):1168-1174. (SCI=2.195, 46/111, 41.4%)

  35. Wen CJ , Yen TC, Al-Suwayeh SA, Chang HW, Fang JY*. In vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanoparticles with different fatty ester/oil ratios. Nanomedicine. 2011 Accepted. (SCI=6.202, 12/160, 7.5%.)

  36.   Shih TC, Wen CJ , Yeh TS, Tien YJ, Lee YS, Yen TC, Hsieh SY*. A novel microRNA-214 /hepatoma-derived growth factor paracrine mechanism contributes to hypervascularity of human hepatocellular carcinoma. Journal of Clinical Investigation. 2011 In submission . (SCI=14.152, 3/106, 2.8 %)

  37. Fu JF, Yen TH, Wen CJ , Chen Y, Hsu CL*. Cooperation of MLL/AF10(OM-LZ) with KRAS G 12C induced myeloproliferative disease-like myeloid leukemia and myeloid sarcoma in a mouse bone marrow transplantation model. Blood. 2011 In submission. (SCI=10.558, 2/65, 4.0 %)

  38.   Zhang LW, Wen CJ, Al-Suwayeh SA, Yen TC, Fang JY*. Cisplatin and quantum dots encapsulated in liposomes as multi-functional nanocarriers for drug delivery and bioimaging. Journal of Nanoparticle Research. 2011 In submission (Co-first author) (SCI=3.250, 33/222, 14.9 %)

  39. Toh CH, Wei KC,Ng SH, Wan YL, Lin CP, Castillo M. Differentiation of Brain Abscesses from Necrotic Glioblastomas and Cystic Metastatic Brain Tumors with Use of Diffusion Tensor Imaging. AJNR. 2011;32. (SCI=3.464, 3/14, 21.4 %)

  40. Toh CH, Wei KC, Ng SH, Wan YL, Castillo M.,Lin CP. Differentiation of Tumefactive Demyelinating Lesions from High-grade Gliomas with Use of Diffusion Tensor Imaging. AJNR. 2011. (SCI=3.464, 3/14, 21.4 %)

  41. Hsua SH, Saleh A. Al-Suwayeh, Chenc CC, Chic CH, Fang JY. PEGylated Liposomes Incorporated with Nonionic Surfactants as an ApomorphineDelivery System Targeting the Brain: In Vitro Release and In Vivo Real-time Imaging. Current Nanoscience. 2011;7:191-199.(SCI=1.879, 79/160, 49.4%.)

  42. Lee TH, Liu HL, Yang HT, Yang JT, Yeh MY. Aging and hypertension may induce brain MR diffusion-perfusion disparity in rat. Exp Neurol 2011; 227:314-321. (SCI=4.436, 55/237, 23.2%.)

  43. Lee TH, Liu HL,Yang ST, Yang JT, Yeh MY, Lin JR. Effects of aging and hypertension on cerebral ischemic susceptibility:evidenced by MR diffusion-perfusion study in rat. Experimental Neurology. 2011;227:314-321 (SCI=4.416,49/243, 20%)
  • 專利

  1. Kun-Ju Lin , Ing-Tsung Hsiao, Tzu-Chen Yen. Precise functional image spatial normalization using early-phase perfusion-like image template (Provisional), USA 61421369 , 2011 。

  2. K-C Wei, H-L Liu , M-Y Hua, Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain ,美國發明專利,申請中, 2011 。

  3. 劉浩澧 、蔡宏杰、盧郁仁、魏國珍,手術導航系統輔助之聚焦式超音波腦部藥物釋放,中華明國發明專利 / 美國發明專利,申請中, 2011 。