• 期刊發表(2010年)

  1. Hsu SH, Wen CJ , Al-Suwayeh SA, Chang HW, Yen TC, Fang JY. 2010. Physicochemical characterization and in vivo bioluminescence imaging of nanostructured lipid carriers (NLCs) for brain targeting: the role of polysorbate 80 and polyethylene glycol. Nanotechnology . 2010. 21: 405101. (SCI=3.137; 2/79; 2.5 %)

  2. Chen FH, Chiang CS, Wang CC, Fu SY, Tsai CS, Jung SM, Wen CJ , Lee CC, Hong JH. Tumors growing in pre-irradiated tissues have two distinct tumor microenvironments yielding different responses to radiotherapy and anti-angiogenesis therapy. Clinical cancer research. In submission (SCI=6.747; 16/165; 9.7% )

  3. Juang JH, Wang JJ, Shen CR, Kuo CH, Chien YW, Kuo HY, Tsai ZT, Yen TC. Magnetic resonance imaging of transplanted mouse islets labeled With chitosan-coated superparamagnetic iron oxide nanopacticles. Transplantation Proceedings 2010;42:2104-2018. (SCI=1.055, 90/148, 60.8%)

  4. Tsai ZT, Wang JF, Kuo HY, Shen CR, Wang JJ, Yen TC. In situ preparation of high relaxivity iron oxide nanoparticle by coating with chitosan ： a potential MRI contrast agent useful for cell tracking. J Magn Magn Mater 2010;322: 208-213 。 (SCI=1.283, 83/192, 43.2%)

  5. Shen CR, Juang JH, Tsai ZT, Wu ST, Tsai FY, Wang JJ, Liu CL, Yen TC. Preparation, Characterization and application of superparamagnetic iron oxide encapsulated with N-[(2-hydroxy-3-trimethylammonium) propyl] Chitosan Chloride. Carbohydrate Polymer. Accepted. (SCI=3.167; 5/64; 7.8% )

  6. Shen CR, Wu ST , Tsai ZT, Yen TC, Tsai JS, Liu CL. Characterization of the quaternized chitosan stabilized iron-oxide nanoparticles as a novel potential MRI Contrast agent for cell tracking. Polymer International. Accepted. (SCI=2.137; 22/76; 28.9% )

  7. Lu PL , Chen YC, Ou TW, Chen HH, Tsai HC, Wen CJ, Lo CL, Wey SP, Lin KJ, Yen TC, Hsiue GH. Doxorubicin-loaded multifunctional hollow micelles based on graft-diblock copolymers for cancer therapy. Biomaterials (submit) (SCI=7.365; 2/59; 3.4% )

  8. Lu PL , Ou TW, Lin SY, Chen YC, Yen TC, Lo CL, Chen H, Hsiue GH. Preparation and drug delivery application of highly stable pegylate-liposome via polyelectrolytic crosslinking. Angewandte Chemie. (submit ) (SCI=11.829; 5/138; 3.6%)

  9. Chen YC, Liao LC, Lu PL , Lo CL, Tsai HC, Huang CY, Wei KC, Hsiue GH. Biodegradable thermo and pH dual responsive micelles with transient stability for anti-cancer drug delivery(submit) Angewandte Chemie. (submit) (SCI=11.829; 5/138; 3.6%)

  10. Yen TC, Wey SP, Liao CH, Yeh CH, Shen DW, Achilef S, Wun TC .  Measurement of the binding parameters of annexin derivatives-erythrocyte membrane interactions.  Anal. Biochem. 2010;406:70-79. (SCI=3.287; 18/65; 27.7%)

  11.   Yao CH, Lin KJ, Weng CC, Hsiao IT, Ting YS, Yen TC, Jan TR, Daniel Skovronsky, Kung MP , Wey SP . GMP-compliant automated synthesis of [ 18F ]AV-45 (Florbetapir F 18) for imaging β-amyloid plaques in human brain . Applied Radiation and Isotopes . 2010 in press. (SCI=1.094;29/44;65.91%)

  12. KJ Lin , WC Hsu, IT Hsiao, SP Wey, LW Jin, D Skovronsky, YY Wai, HP Chang, CW Lo, CH Yao, TC Yen, MP Kung. Whole-Body Biodistribution and Brain PET Imaging with 18F -AV-45, a Novel Amyloid Imaging Agent-a Pilot Study. Nuclear Medicine and Biology 2010 ;37:497-508. . (SCI=2.456, 35/104, 18.8%)

  13. IT Hsiao ＃ , KJ Lin ＃ , SI Chang, TC Yen, TC Chen, TS Yeh. Impaired liver regeneration of steatotic rats after portal vein ligation: particular emphasis on 99mTc-DISIDA scintigraphy and adiponectin signaling. J. Hepatology . 2010; 52:540-549 . (SCI=7.818, 4/65, 9.1%)

  14. Hsieh HH, Hsiao IT *. Image Reconstructions from Limit Views and Angle Coverage Data for a Stationary Multi-Pinhole SPECT System. Tsinghua Science & Technology . 2010:15; 44-49.

  15. Hsiao IT * , HM Huang. An accelerated ordered subsets reconstruction algorithm using an accelerating power factor for emission tomography. Physics in Medicine and Biology. 2010;55:599-614. (SCI=2.781, 25/104, 17%)

  16. Lee PW, Hsu SH, Wang JJ, Tsai JS, Lin KJ , Wey SP, Chen FR, Lai CH, Yen TC, Sung HW. The characteristics, biodistribution, magnetic resonance imaging and biodegradability of superparamagnetic core-shell nanoparticles. Biomaterials. 2010; 31:1316-1324. (SCI=7.365;2/59;3.39%)

  17. Lin CY, Chang YH, Lin KJ , Yen TC, Tai CL, Chen CY, Lo WH, Hsiao IT, Hu YC. in Rabbits Using Baculovirus-Engineered Mesenchymal Stem Cells. Biomaterials. 2010; 31:3222-3230. (SCI=7.365;2/59;3.39%)

  18. Sonaje K, Chen YJ, Chen HL, Wey SP, Juang JH, Nguyen HN, Hsu CW, Lin KJ , Sung HW. Enteric-coated capsules filled with freeze-dried chitosan/poly(gamma-glutamic acid) nanoparticles for oral insulin delivery. Biomaterials. 2010;31:3384-94. (SCI=7.365;2/59;3.39%)

  19.   Lin KJ , Hsu WC, Hsiao IT, Wey SP, Jin LW, Daniel Skovronsky, Wai YY, Chang HP, Lo CW, Yao CH, Yen TC, Kung MP. Whole-Body Biodistribution and Brain PET Imaging with 18F -AV-45, a Novel Amyloid Imaging Agent-a Pilot Study. Nucl Med Biol. 2010;37:497-508. (SCI=2.456;35/104;33.65%)

  20. Tsao HH, Lin KJ , Juang JH, Daniel M. Skovronsky, TC Yen, SP Wey, Kung MP . Binding characteristics of 9-fluoropropyl-(+)-dihydrotetrabenzazine (AV-133) to the vesicular monoamine transporter type 2 in rats. Nucl Med Biol. 2010;37:413-9. (SCI=2.456;35/104;33.65%)

  21.   Lin TJ, Huang CC, Wang IJ, Lin JW, Hung KS, Ling Fan, Tsao HH, Yang NS, Lin KJ * . Validation of an animal FDG PET imaging system for study of human glioblastoma xenograft in mouse and rat glioma models.  Ann Nucl Med Sci 2010;23:77-83. (non SCI)

  22. Kiran Sonajea, Lin KJ * , Wey SP, Lin CK, Yeh TH, Nguyen HN, Hsu CW, Yen TC, Juang JH, Sung HW. Biodistribution, Pharmacodynamics and Pharmacokinetics of Insulin Analogues in a Rat Model: Oral Delivery Using pH-Responsive Nanoparticles vs. Subcutaneous Injection.  Biomaterials. 2010;31:6849-58. (SCI=7.365;2/59;3.39%)

  23. Lin KJ , Weng YH*, Wey SP, Hsiao IT, Lu CS, Daniel Skovronsky, Chang HP, Kung MP*, Yen TC. Whole-Body Biodistribution and Radiation Dosimetry of 18F -FP-(+)-DTBZ ( 18F -AV-133) – a Novel Vesicular Monoamine Transporter 2 Imaging Agent. J Nucl Med 2010; 51:1480–1485. (SCI=6.424;1/104;0.96%)

  24. Liu H L, Lyu L A, Wu J S, Shen C R, Wai Y Y, Chen J C, Yen T C, Wang J J* In Vivo Assessment of Macrophage CNS Infiltration during Disruption of the Blood-brain Barrier with Focused Ultrasound: A Magnetic Resonance Imaging Study. Journal of Cerebral Blood Flow and Metabolism 2010; 30: 177-186 (SCI=5.741, 24/221, 10.9%)

  25. Lin Y C, Wang C C, Wai Y Y, Wan Y L, Ng S H, Chen Y L, Liu H L, Wang J J * . Significant temporal evolution of diffusion anisotropy in the evaluation of early response after radiosurgery in patients with vestibular schwannoma: findings from functional diffusion maps. American Journal of Neuroradiology 2010; 31: 269-274. (SCI=2.745, 3/12, 25%)

  26. Liu H L, Hua M Y, Cheng P Y, Chu P C , Pan C H, Yang H W, Huang C Y, Wang J J , Yen T C, Wei K C*. Blood–Brain Barrier Disruption by Using Focused US Enhances Delivery of Chemotherapeutic Drugs for Glioblastoma Treatment. Radiology 2010 ; 255: 415-425. (SCI=5.996, 2/90, 2.2%)

  27. Huang Y Z, Rothwell, J. C., Lu, C S, Wang JJ , and Chen, R S. Restoration of motor inhibition through an abnormal premotor-motor connection in dystonia. Movement Disorders 2010 ; 25: 696-703. (SCI=3.898, 21/156,13.5%)

  28. Chang C C, Chang W N, Lui C C, Lee Y C, Wang JJ , Chen SS, Lin M H, Lin Y T, Wang Y L. Longitudinal Study of Carbon Monxide Intoxication by Diffusion Tensor Imaging with Neuospsychiatric Correlation. Journal of Psychiatry & Neuroscience 2010 ; 35: 115-125. (SCI=4.123, 19/101,18.8%)

  29. Chen PY, Liu HL, Hua MY, Yang HW, Huang CY, Chu PC , Lyu LA, Tsai HC, Chen SM, Lu YJ, Wang JJ, Yen TC, Ma YH, Wu T., Chen JP, Chuang JI, Shin JW, Hsueh C., Wei KC. Novel Magnetic/Ultrasound Focusing System Enhances Nanoparticle Drug Delivery for Glioma Treatment. 2010 ; 00: 1-12. (SCI=4.984, 17/167, 10.2%)

  30. Wang J J , Wai Y Y, Lin W Y, Ng S H, Wang C H, Hsieh C H, Chen R S, Lu P S, Lu C S* Microstructural Changes in Patients with Progressive Supranuclear Palsy: A Diffusion Tensor Imaging Study. Journal of Magnetic Resonance Imaging 2010 ; 32:69-75 . (SCI=2.658, 29/92, 31.5%)

  31. Yu JF, Wang SR, Chen CK, Wu CM, Ng SH, Ying Leslie, Y Huang Z, Wang JJ. Activation of the Auditory Cortex in Subjects with Unilateral Sensorineural Hearing Impairment in Response to Hearing Their Own Names. Journal of Medical and Biological Engineering 2010 ; 30: 21 5-219.

  32. Lin CY, Chen WH, Liao CT, Chen IH, Chiu CC, Wang HM, Yen TC , Lee LY, Chang JT, Cheng AJ. Positive association of glucose-regulated protein 78 during oral cancer progression and the prognostic value in oral precancerous lesions. HEAD NECK-J SCI SPEC. 2010 ;32:1028-39. (SCI=2.283,45/167,26.9%)

  33. Ng SH, Chan SC, Yen TC , Liao CT, Chang JT, Ko SF, Wang HM, Lin CY, Chang KP, Lin YC. Comprehensive imaging of residual/recurrent nasopharyngeal carcinoma using whole-body MRI at 3 T compared with FDG-PET-CT. Eur Radiol 2010 Apr 15. [Epub ahead of print] (SCI=3.589,13/104,12.5%)

  34. Yen TC , Liao CT. Statistical Issues Involved in "Risk Stratification of Patients with Oral Cavity Squamous Cell Carcinoma and Contralateral Neck Recurrence Following Radical Surgery" Ann Surg Oncol 2010 May 19. [Epub ahead of print] (SCI=4.13,6/167,3.6%)

  35. Chang YC, Chen YJ, Wu CH, Wu YC, Yen TC , Ouyang P. Characterization of centrosomal proteins Cep55 and pericentrin in intercellular bridges of mouse testes. J Cell Biochem 2010;109:1274-85. (SCI=2.935,120/283,42.4%)

  36. Chuang CK, Lin KJ, Lin CY, Chang YH, Yen TC , Hwang SM, Sung LY, Chen HC, Hu YC. Xenotransplantation of Human Mesenchymal Stem Cells into Immunocompetent Rats for Calvarial Bone Repair. Tissue Eng Part A 2010;16:479-88. (SCI=5.82,19/152,12.5%)

  37. Liao CT, Huang SF, Chen IH, Kang CJ, Lin CY, Fan KH, Wang HM, Ng SH, Chuen H, Lee LY, Tsao CK, Yen TC *. Outcome Analysis of Patients with pN2 Oral Cavity Cancer. Ann Surg Oncol 2010;17:1118-26. (SCI=4.13,6/167,3.6%) (correspondence)

  38. Lai CH, Yen TC , Ng KK. Surgical and radiologic staging of cervical cancer. Curr Opin Obstet Gyn 2010;22:15-20. (SCI=2.491,14/70,20%)

  39. Liu HL, Hua MY, Chen PY, Chu PC , Pan CH, Yang HW, Huang CY, Wang JJ, Yen TC , Wei KC. Blood-Brain Barrier Disruption by Focused Ultrasound Enhances Delivery of Chemotherapeutic Drugs for Glioblastoma Treatment. Radiology 2010;255:415-25. (SCI=6.341,2/104,1.9%)

  40. Liu HL, Wai YY, Hsu PH, Lyu LA, Wu JS, Shen CR, Chen JC, Yen TC *, Wang JJ *. In Vivo Assessment of Macrophage CNS Infiltration during Disruption of the Blood-brain Barrier with Focused Ultrasound: A Magnetic Resonance Imaging Study. J CEREBR BLOOD F MET 2010;30:674 (SCI=5.457,14/105,13.3%) (correspondence)

  41. Tsai HC, Chang WH, Lo CL, Tsai CH, Chang CH, Ou TW, Yen TC , Hsiue GH. Graft and diblock copolymer multifunctional micelles for cancer chemotherapy and imaging. Biomaterials 2010;31:2293-301. (SCI=7.365,2/59,3.4%)

  42.   Chan SC, Lin CY, Ng SH, Chang Joseph T, Wang HM, Liao CT, Lo CW, and Yen TC * .18F -FDG PET for retropharyngeal lymph node metastasis in oropharyngeal and hypopharyngeal cancers: impact on diagnosis and prediction analysis. NUCL MED COMMUN 2010;31:260-5. (SCI=1.315,67/104,64.4%) (correspondence)

  43.   Chou HH, Chang HP*, Lai CH, Ng KK, Hsueh S, Wu TI, Chen MY, Yen TC , Hong JH, Chang TC. (18)F-FDG PET in stage IB/IIB cervical adenocarcinoma/adenosquamous carcinoma. Eur J Nucl Med Mol I 2010;37:728-35. (SCI=4.531,7/104,6.7%)

  44. Tsai CS, Lai CH, Chang TC, Yen TC , Ng KK, Hsueh S, Lee SP, Hong JH. A Prospective Randomized Trial to Study the Impact of Pretreatment FDG-PET for Cervical Cancer Patients with MRI-Detected Positive Pelvic but Negative Para-Aortic Lymphadenopathy. Int J Radiat Oncol 2010;76:477-84. (SCI=4.592,6/104,5.8%)

  45. Liao CT, Wang HM, Chang JT, Lin CY, Ng SH, Huang SF, Chen IH, Hsueh C, Lee LY, Lin CH, Cheng AJ, Yen TC *. Influence of pathological nodal status and maximal standardized uptake value of the primary tumor and regional lymph nodes on treatment plans in patients with advanced oral cavity squamous cell carcinoma. Int J Radiat Oncol 2010;77:421-9. (SCI=4.592,6/104,5.8%) (correspondence)

  46. Lai CH, Yen TC. When and how often should PET scans be performed in the management of cervical cancer? EXPERT REV ANTICANC. 2010;10:983-6. (SCI=2.493,82/166,49.4%)

  47. Liao CT, Huang SF, Chen IH, Kang CJ, Lin CY, Fan KH, Wang HM, Ng SH, Hsueh C, Lee LY, Lin CH, Yen TC*. Tongue and Buccal Mucosa Carcinoma: Is There a Difference in Outcome? Ann Surg Oncol. 2010 Jun 22. [Epub ahead of print] (SCI=4.13,6/167,3.6%) (correspondence)

  48. Liao CT, Lee LY, Huang SF, Chen IH, Kang CJ, Lin CY, Fan KH, Wang HM, Ng SH, Yen TC*. OUTCOME ANALYSIS OF PATIENTS WITH ORAL CAVITY CANCER AND EXTRACAPSULAR SPREAD IN NECK LYMPH NODES. Int J Radiat Oncol. 2010 July Accepted (SCI=4.592,6/104,5.8%) (correspondence)

  49. Chen YJ, Liao CT, Chen PJ, Lee LY, Li YC, Chen IH, Wang HM, Chang JTC, Chen LJ, Yen TC, Tang CY, Cheng AJ*. Down-regulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract. Head Neck. 2010 Feb 1 [in press]. (SCI=2.283,45/167,26.9%)

  50. Lin WY , Lin KJ, Weng YH, Yen TC, Shen LH, Liao MH, Lu CS. Preliminary studies of differential impairments of the dopaminergic system in subtypes of progressive supranuclear palsy. Nucl Med Commun. Accepted no 17 July 2010 (SCI=1.315,67/104,64.4%)

  51. Chen PY, Liu HL, Hua MY, Yang HW, Huang CY, Chu PC , Lyu LA, Tsai HC, Chen SM, Lu YJ, Wang JJ, Yen TC, Ma YH, Wu T., Chen JP, Chuang JI, Shin JW, Hsueh C., Wei KC. Novel Magnetic/Ultrasound Focusing System Enhances Nanoparticle Drug Delivery for Glioma Treatment. Neuro-oncology, Accepted (SCI=4.984,17/167,10.2%)

  52. Liang CC, Tseng LH, Ko YS, Lee TH . Expression of Nerve Growth Factor Immunoreactivity and Messenger RNA in Ischemic Urinary Bladder. Neurourology and Urodynamics 2010;29:512–516. (SCI= 2.693,18/63,28.6%)

  53. Shieh CC, Hu HH, YangST, Lee TH, Hsu JC, Wai YY, Wong HF, Chung CP. Validation of the Jugular Venous Reflux Animal Model by Three-Dimensional Time-of-Flight MRA with a Clinical Scanner. Cerebrovascular Diseases 2010;30:167–171. (SCI=3.535; 35/167; 20.9% )

  • 專利

  1. 蔡瑞燦、蔡福源、沈家瑞、王忍妃、 吳淑婷、 閻紫宸； 2010 ；「 製作磁性四級銨幾丁聚醣磁振造影對比劑 」中華民國專利。