1. Wen-Yi Lee (Wen-I Lee), Mei-Hui Yang, Li-Chen Chen, Syh-.lae l,in, Jing-Long Huang. Role of serum eosinophil cationic protein in the monitoring of children with brohchial asthma and rhinitis. Pediatr Asthma Allergy Immunol 1998;12:129-38

2. Wen-Yi Lee (Wen-I Lee), Mei-Hui Yang, Kam-Fai Lee, Li-Chen Chen, Syh-Jae Lin, Kuo-Wei Yeh, Jing- Long Huang. PFAPA syndrome (Periodic fever, Aphthous Stomatitis, Pharyngitis, Adenitis) Clinicl Rheumatol 1999; 18:207-13

3. Jing-Long Huang, Wen-Yi Lee (Wen-I Lee), Li-Chen Chen, Ming-Ling Kuo, Kue-Hsiung Hsieh. Changes of serum levels of interleukin-2, intercellular adhesion molecule-1, endothelial leukocyte adhesion molecule-1 and Th1 and Th2 cell in severe atopic dermatitis after intravenous immunoglobulin therapy. Ann Allergy asthma Immunol 2000;84:345-352

4. Mei-Hui Yang, Wen-Yi Lee, (Wen-I Lee), Li-Chen Chen, Syh-Jae Lin, Jing-Long Huang. Intraarticular Triamcinolone E lexacetonide Injection in Children with Juvenile Chronic Arthritis (JCA): A Survey of Clinical Practice. ActaPaed Sin 1999;40:182-5

5. Jing-Long Huang, Iou-Jih Hung, Li-Chen Chen, Wen-Yi Lee, Cheun Hsueh, Kue-Hsiung Hsieh. Successfully treated sulfasalazine-induced fulminant Hepatic failure, throlllbocytopenia and earthward hypoplasia with IVIG. Clinical Rheumatol 1998; 17:349-52.

6. Syh-Jae Lin, Hsun-Chin Chao, Mei-Hui Yang,Wen-Yi Lee (Wen-l Lee), Jing-Long Huang, The effect of heparinization and overnight storage of blood samples on eosinophil catonic protein levels in asthmatic children and controls. Pediatr Asthma Allergy Immunol 1999; 13: 25 -31

7. Syh-Jae Lin, Jing-Long l luang, Hsun-Chin Chao,Wen-Yi Lee (Wen-I Lee), Mei-Hui Yang. A Follow-up study of systemic onset juvenile rheumatoid arthritis in children. Acta Paed Sin 1999;40: 176-81

8. Kohsuke Imai, Geir Slupphaug, Wen-I Lee, Patrick Revy, Shigeaki Nonoyama, Nadia Catalan, Leman Yel, Monique Forveille, Hans E. Krokan, Hans D. Ochs, Alain Fischer, Anne Durandy: Uracil-DNA glycosylase deficiency proundly impairs immunoglobulin class switch recombination, leading to a hyper-IgM syndrome. Nat Immunol 2003; 4:1023-8

9. Wen-I Lee, Quli Zhu, Elonora Gambineri, YinZhu Jin, Andrew A Walcher, Hans D. Ochs: Inducible CO-Stimulator molecule (ICOS), a candidate gene for defective isotype switching, is normal in patients with Hyper IgM syndrome of unknown molecular diagnosis. J Allergy Clin Immunol 2003; 112:958-64

10. David R. Freyer, L. Kate Gowans, Michael Warzynski, Wen-I Lee. Flow cytometric diagnosis of X-linked hyper-IgM syndrome: application of an accurate and convenient procedure. J Pediatr Hematol Oncol 2004; 26:263-370

11. Wen-I Lee, Troy R. Torgerson, Michael J. Schumacher, Leman Yel, Qili Zhu, Hans D. Ochs. Mutation analysis in a large cohort of patients with hyper IgM syndrome (HIGM). Blood 2005; 105:1881-1890

12. Jeng-Juh Hung, Liang-Shiou Ou, Wen-I Lee, Jing-Long Huauang. Central nervous system infection in patients with systemic lupus erythematosus. J Rheuma 2005; 32:40-43

13. Wen-I Lee,* Ming-Ling Kuo,* Jing-Long Huang, Syh-Jae Lin, Cheng-Jang Wu. Distribution and clinical aspects of primary Immunodeficiency diseases in a Taiwan pediatric tertiary hospital during 20 years. J Clin Immunol 2005; 25:162-173. (Theses first two authors contributed equally; * correspondence)

14. Hans D. Ochs, Troy R. Torgerson, Wen-I Lee, YinZhu Jin, Elonora Gambineri, Qili Zhu. The molecular basis of primary immune deficiency deficiency diseases. Intravenous immunoglobulins in the third millennium. (2004) First Edition. MC Dalakas and Peter J. Spath eds Parthenon Publishing, New York , NY & London , UK (Book)

15. Chih-Hsun Yang, Wen-I Lee,* TS Jeffrey Hsu. Disseminated white papules: Molluscum Contagenosum infection in a female patient with hyper IgE syndrome. Arch Dermatol 2006; 142:755-80 (* correspondence)

16. Wen-I Lee. A molecular approach to study the patients with Hyper IgM syndrome characterized by defective class switch recombination. (Book)

17. Yi-Chun Ma, Wen-I Lee, Sheng-Chieh Lin, Shyh-Dar Shyur, Li-Hsin Huang. De novo mutation causing X-linked hyper-IgM syndrome: a family study in Taiwan . Asian Pac J Allergy Immunol. 2005; 23:53 -9.

18. Sheng-Chieh Lin, Shyh-Dar Shyur, Yi-Chun Ma, Li-Hsin Huang, Wen-I Lee. Recurrent acalculous cholecystitis and sclerosing cholangitis in a patient with X-linked hyper-immunoglobulin M syndrome. J Formos Med Assoc. 2005;104:421-6.

19. Sheng-Chieh Lin, Shyh-Dar Shyur, Yi-Chun Ma, Li-Hsin Huang, Wen-I Lee. Hyper-IgM1 syndrome with interstitial pneumonia and diarrhea caused by coxsackievirus B4 in a 3-month-old infant. Ann Allergy Asthma Immunol. 2005;95:93-7.

20. Hong-Ren Yu, Rong-Fu Chen , Kuo-Ching Hong, Chin-Nam Bong, Wen-I Lee,

Ho-Chang Kuo , Kuender D. Yang IL-12-independent Th1 polarization in human mononuclear cells infected with varicella-zoster virus. Eur J Immunol. 2005;35:3664-72.

21. Wen-I Lee, Tang-Her Jaing, Meng-Ying Hsieh, Ming-Ling Kuo, Syh-Jae Lin, Jing-Long Huang. Distribution, Infections, Treatments and Molecular Analysis in a Large Cohort of Patients with Primary Immunodeficiency Diseases (PIDs) in Taiwan . J Clin Immunol. 2006; 26:274-83

22. Wen-I Lee, Jing-Long Huang, Tang-Her Jaing, Ming-Ling Kuo, Syh-Jae Lin. Analysis of Btk, CD40L, SAP, ICOS, ICOS ligand, TACI, BAFFR and CD19 in patients diagnosed as common variable immunodeficiency (CVID). (J Clin Immunol, submitted)

23. Wen-I Lee, Tang-Her Jaing, Tzou-Yien Lin, Jing-Long Huang, Shih-Hsiang Chen, Robert Chow . Successful Unrelated Mismatched Cord Blood Transplantation in an Infant with Severe Combined Immunodeficiency and Mycobacterium bovis Bacillus Calmette-Guerin Disease. Pediatr Transplant 2006;10:501-4.

24. Sheng-Chieh Lin, Shyh-Dar Shyur, Wen-I Lee, Yi-Chun Ma, Li-Hsin Huang X-Linked Hyper-Immunoglobulin M Syndrome: Molecular Genetic Study and Long-Time Follow-Up of Three Generations of a Chinese Family. Int Arch Allergy Immunol. 2006 140:1-8.

25. Tang-Her Jaing, Jia-Woei Hou, Shih-Hsiang Chen, I-Anne Huang, Chao-Jan Wang, Wen-I Lee. Successful unrelated mismatched cord blood transplantation in a child with malignant infantile osteopetrosis. Pediatr Transplant. 2006;10:629-31.

26. Tsung-Chieh Yao , Ming-Ling Kuo, Lai-Chu See, Liang-Shiou Ou, Wen-I Lee, Chin-Kan Chan, Jing-Long Huang. RANTES and monocyte chemoattractant protein 1 as sensitive markers of disease activity in patients with juvenile rheumatoid arthritis: A six-year longitudinal study. Arthritis Rheum. 2006;54:2585-2593

27. Jing-Long Huang, Jeng-Juh Hung, Kun-Chan Wu, Wen-I Lee, Chin-Kan Chan, Liang-Shiou Ou. Septic Arthritis in Patients with Systemic Lupus Erythematosus: Salmonella and Nonsalmonella Infections Compared. Semin Arthritis Rheum 2006;36:61-67

28.Tang-Her Jaing*, Bih-Yu Tsai, Shih-Hsiang Chen, Wen-I Lee, Kuei-Wen Chang, Shih-Ming Chu: Early transplantation of unrelated cord blood in a two-month-old infant with Wiskott–Aldrich syndrome. Pediatr Transplant 2007;11:557-9.

29. Wen-I Lee,* Chang-Yo Yang, Don-Her Jiang, Yin-Hsiu Chien, Kuei-Wen Chang, Jing-Long Huang. Clinical Aspects and Molecular Analysis of Chinese Patients with Wiskott-Aldrich Syndrome (WAS) in Taiwan. Int Arch Allergy Immunol. 2008;145:15-23.

30. Wen-I Lee,* Jing-Long Huang, Tang-Her Jaing, Ming-Ling Kuo, Syh-Jae Lin. Analysis of genetic defects in patients diagnosed as common variable immunodeficiency (CVID). Ann Allergy Asthma Immunol. 2007;99:433-42.

31.Yi-Chan Tsai^, Wen-I Lee,^*, Jing-Long Huang, Iou-Jih Hung, Tang-Her Jaing, Mai-Tzu Chen, and Ming-Ling Kuo. Leukocyte adhesion disease type I with CD18 splicing mutation but without delayed umbilical cord separation. Pediatr Allergy Immunol. 2008;19:25-32.

32.Fang-Chen Liang, Yi-Chia Wei, Tang-Her Jiang, Meng-Ying Hsieh, Yu-Chuan Wen, Yi-Shiou Chiou, Shu-Hua Wu, Li-Chen Chen, Jing-Long Huang, Wen-I Lee* The Updated Classification and Current State of Primary ImmunoDeficiency Diseases (PIDD) in Taiwan. Acta Paediatr Tw. 2008;49: 3-8

33.Tang-Her Jaing*, Chien-Feng Sun, Wen-I Lee, Yu-Chuan Wen, Chao-Ping Yang, Iou-Jih Hung. Successful unmanipulated peripheral blood progenitor cell transplantation from an HLA haploidentical 2-locus-mismatched mother in a thalassemic patient with primary graft failure after transplantation of bone marrow and cord blood from unrelated donors. Pediatr Transpantation 2008;12:232-4.

34.Kuan-Ying Huang, Ming-Wei Lai, Wen-I Lee, Yhu-Chering Huang*. Fatal cytomegalovirus gastrointestinal disease in an infant with Wiskott-Aldrich syndrome. J Formos Med Assoc. 2008;107:64-7.

35.Wen-I Lee*, Shih-Hsiang Chen, Iou-Jih Hung, Chao-Ping Yang, Tang-Her Jaing, Chin-Jung Chen, Shin-Pai Li, Jing-Long Huang. Clinical Aspects, Immunologic Assessment and Genetic Analysis of Taiwanese Children with Hemophagocytic Lymphohistiocytosis. Pediatr Infect Dis J 2008 (accept)

36.Wen-I Lee*, Jing-Long Huang, Tzou-Yien Lin, Chuen Hsueh, Alex M Wong, Meng-Ying Hsieh, Cheng-Hsun Chiu, Tang-Her Jaing. Chinese Patients with Defective IL-12/23-Interferon-γ Circuit in Taiwan: Partial Dominant Interferon-γ Receptor 1 Mutation Presenting as Cutaneous Granuloma and IL-12 Receptor β1 Mutation as Pneumatocele. J Clin Immunol 2008  (submitted) (*correspondence)

37. Yu-Lin Huang, Meng-Ying Hsieh, Pa-Fan Hsiao, Jing-Long Huang, Wen-I Lee*. Alopecia Areata Universalis after Phenobarbital Hypersensitivity. Int Arch Allergy Immunol. (submited)(*correspondence)

38. Wen-I Lee, Tang-Her Jaing, Iou-Jih Hung, Ming-Ling Kuo, Jing-Long Huang Subtle and Diverse Immune Alternations in Beta-Thalassemic Patients Preceding the Significant Manifestations of Iron Overload and Some Dysfunction Corrected by Unrelated Cord Blood Transplantation (submitted to Haematologica)

39. Meng-Ying Hsieh, Wen-I Lee,* Tang-Her Jaing, Shyh-Dar Shyur, Li-Chen Chen, Syh-Jae Lin, Jing-Long Huang.* Molecular Analysis in Two Taiwanese Families with X-linked Severe Combined Immunodeficiency (submitted; The first two authors contributed equally; * correspondence)

40. Wen-I Lee,* Ton-Her Jiang, Jing-Long Huang, Ming-Ling Kuo, Li-Chen Chen, Syh-Jae Lin. De novo mutation of neutrophil elastase 2 (ELA2) in a Taiwanese infant with severe congenital neutropenia (submitted; * correspondence)

41. Yi-Chia Wei, Wen-I Lee,* Mai-Tzu Chen, Ming-Ling Kuo, Li-Chen Chen, Jing-Long Huang. Molecular Analysis and Polymorphonuclear Cellular Function in Two Taiwanese Families with X-linked Chronic Granulomatous Disease (submitted; * correspondence)

42. Lee WI, Liang FC, Huang JL, Jaing TH, Wang CH, Lin TY, Huang YC, Huang WL, Jou R, Hsieh MY, Chia JH, Wu TL. Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced disease. J Clin Immunol 2009; May 29(3):319-29.

43. Lee WI, Huang JL, Jaing TH, Wu KH, Chien YH, Chang KW. Clinical aspects and genetics analysis of Taiwanese patients with Wiscott- Aldrich syndrome protein mutation: the first identification of X- linked thrombocytopenia in the Chinese with novel mutation. J Clin
Immunol 2010 Jul;30(4):593-601.

44.Lee WI*, Huang JL, Lin SJ, Yeh KW, Chen LC, Hsieh MY, Kuo HC, Yang KD, Yu HR, Jaing TH. Clinical aspects and genetic analysis of Taiwanese patients with phenotypes of hyperimmunoglobulin E recurrent infection syndrome (HEIR). J Clin Immunol 2010 Dec 1
(Online pulished)

45. Lee WI,* Huang JL, Huang YC, Lin SJ, Yeh KW, Chen LC, Hsieh MY, Kuo HC, Kunder D. Yang, Yu HR, Jaing TH. Clinical Aspects and Genetic Analysis of Taiwanese Patients with the Phenotype of Hyper-Immunoglobulin E Recurrent Infection Syndromes (HIES). J Clin Immunol. 2011;31:272-80 (IF=3.077; Immunology 63/139 = 45.32 %)

46. Lee WI,* Huang JL, Huang YC, Lin SJ, Yeh KW, Chen LC, Hsieh MY, Yu HR, Kuo HC, Kunder D. Yang, Jaing TH. Clinical, Immunological and Genetic Features of Taiwanese Patients with the Phenotype of Hyper-Immunoglobulin E Recurrent Infection Syndromes (HIES). Immunobiology. 2011;216:909-17 (IF=3.205; Immunology 61/139=43.88%)

47.Wu CT, Ou LS, Yeh KW, Lee WI, Huang JL. Serum heat shock protein 60 can predict remission of flare-up in juvenile idiopathic arthritis. Clin Rheumatol. 2011; 30:959-65. (IF=1.996; Rheumatology 18/29 = 62.07 %)

48. Yao TC, Ou LS, Lee WI, Yeh KW, Chen LC, Huang JL; PATCH study group. Exhaled nitric oxide discriminates children with and without allergic sensitization in a population-based study. Clin Exp Allergy. 2011;41:556-64. (IF=5.032; Allergy 3/24 = 12.50 %)

49. Huang JL, Yeh KW, Yao TC, Huang YL, Chung HT, Ou LS, Lee WI, Chen LC. Pediatric lupus in Asia. Lupus. 2010;19:1414-8. (IF=2.337; Rheumatology 15/29 = 51.72 %)

50. Tu YL, Yeh KW, Chen LC, Yao TC, Ou LS, Lee WI, Huang JL. Differences in disease features between childhood-onset and adult-onset systemic lupus erythematosus patients presenting with acute abdominal pain. Semin Arthritis Rheum. 2011;40:447-54. (IF=4.969; Rheumatology 5/29 = 17.24 %)

51. Lee WI,* Huang JL, Jaing TH, Shyur SD, Yang KD, Chien YH, Chiang BL, Soong WJ, Chiou SS, Shieh CC, Lin SJ, Yeh KW, Chen LC, Ou LS, Yao TC, Lin TY, Chiu CH, Huang YC, Wu KH, Lin CY, Yu HH, Yang YH, Yu HR, Yen HJ, Hsieh MY, Kuo ML, Hwu WL, Tsai YC, Kuo HC, Lin YL, Shih YF, Chang KW. Distribution, clinical features and treatment in Taiwanese patients with symptomatic primary immunodeficiency diseases (PIDs) in a nationwide population-based study during 1985–2010. Immunobiology. 2011;216:1286-94. (IF=3.205; Immunology 61/139=43.88%)

52. Yao TC, Lee WI, Ou LS, Chen LC, Yeh KW, Huang JL; for the PATCH Study Group.
Reference values of exhaled nitric oxide in healthy asian children age 5 to 18 years. Eur Respir J. 2012;39:378-84. (IF=5.895; Respiratory system 3/48=6.25%)

53. Yao TC, Ou LS, Yeh KW, Lee WI, Chen LC, Huang JL; PATCH Study Group. Associations of age, gender, and BMI with prevalence of allergic diseases in children: PATCH study. J Asthma. 2011;48:503-10. (IF=1.525; Allergy 15/24=62.5%)

54.Yeh KW, Ou LS, Yao TC, Chen LC, Lee WI, Huang JL; PATCH Study Group. Prevalence and risk factors for early presentation of asthma among preschool children in Taiwan. Asian Pac J Allergy Immunol. 2011;29:120-6. (IF=0.649 Allergy 17/24 = 70.83 %)

55.Chang HM, Yu HH, Yang YH, Lee WI, Lee JH, Wang LC, Lin YT, Chiang BL. Successful Treatment of Aspergillus flavus Spondylodiscitis With Epidural Abscess in a Patient With Chronic Granulomatous Disease. Pediatr Infect Dis J. 2012;31:100-1 (IF=3.577, Pediatrics 7/115=6.09%)

56. Lee WI,* Huang JL, Yeh KW, Jaing TH, Lin TY, Huang TC, Chiu CH. Immune defects in active mycobacterial diseases in patients with primary immunodeficiency diseases. J Formos Med Assoc. 2011;110:750-8. (IF=1.132 Medicine, general & internal 78/155 = 50.32 %)

57. Lee WI,* Yao TC, Yeh KW, Chen LC, Ou LS, Huang JL*; the PATCH Study Group. Stronger Toll-like receptor 1/2, 4, and 7/8 but less 9 responses in peripheral blood mononuclear cells in non-infectious exacerbated asthmatic children. Immunobiology. 2012 May 22. [Epub ahead of print] (IF=3.205; Immunology 61/139=43.88%)

58. Lee WI,* Huang JL, Wu TS, Lee MH, Chen IJ, Yu KH, Liu CY, Yang CH, Hsieh MY, Lin YL, Shih YF, Jaing TH, Huang SC, Kuo TT, Ku CL. Patients with inhibitory and neutralizing auto-antibodies to interferon-γ resemble the sporadic adult-onset phenotype of Mendelian Susceptibility to Mycobacterial Disease (MSMD) lacking Bacille Calmette-Guerin (BCG)-induced diseases. Immunobiology. 2012 Aug 31. [Epub ahead of print]. (IF=3.205; Immunology 61/139=43.88%)

59. Liao SL, Lai SH, Huang JL, Lee NC, Lee WI.* Serial cytokine expressions in infants with incontinentia pigmenti. Immunobiology. 2012 Sep 5. [Epub ahead of print] (IF=3.205; Immunology 61/139=43.88%)

60. Chen YJ, Yu HH, Yang YH, Lau YL, Lee WI, Chiang BL. Recurrent abdominal pain as the presentation of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) in an Asian girl: A case report and review of the literature. J Microbiol Immunol Infect. 2012 Aug 23. [Epub ahead of print] (IF=0.987 Infectious disease 63/70 = 90.00 %)

61. Hsieh MY, Hong WH, Lin JJ, Lee WI,* Lin KL, Wang HS, Chen SH, Yang CP, Jaing TH, Huang JL. T-cell receptor excision circles and repertoire diversity in children with profound T-cell immunodeficiency. J Microbiol Immunol Infect. 2012 Jul 23. [Epub ahead of print] (IF=0.987 Infectious disease 63/70 = 90.00 %)

62. Chen SH, Yang CP, Jaing TH, Hung IJ, Shih LY, Ho PC, Lee WI, Huang JL. Clinical impact of in vitro cellular drug resistance on childhood acute lymphoblastic leukemia in Taiwan. Leuk Lymphoma. 2012;53:1536-42. (IF=2.680 Hematology 36/68 = 52.94 %)

63. Yeh KW, Ou LS, Yao TC, Chen LC, Lee WI, Huang JL; PATCH Study Group. Prevalence and risk factors for early presentation of asthma among preschool children in Taiwan. Asian Pac J Allergy Immunol. 2011;29:120-6. (IF=0.649 Allergy 17/24 = 70.83 %)

64. Lee WI,* Chen SH, Huang JL, Jaing TH, Chung HT, Yeh KW, Chen LC, Yao TC, Hsieh MY, Lin SJ, Kuo ML. Identifying patients with neutrophil elastase (ELANE) mutations from patients with a presumptive diagnosis of autoimmune neutropenia. Immunobiology. (2012 in press) (IF=3.205; Immunology 61/139=43.88%)

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