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次專科簡介
  • 每年門診人數約二萬人次。
  • 有設備完善的過敏、氣喘、免疫及風濕學基本設施，包括肺功能檢查機、多項目過敏原測定儀(MAST, CAP)等設施及配合實驗室齊全之分子生物基礎研究設備。
  • 結合兒童醫院醫師及長庚大學臨床醫學研究所高雄分部相關的研究人員，成立了專屬之臨床及基礎醫學實驗室，以達成兼顧臨床、教學及研究的目的，期望接受訓練後之住院醫師、研究員及主治醫師皆能有獨立之臨床診斷、治療、教學和研究之能力。
醫師團隊
Apo_horn
團隊大合照
irasutoya_clipborad_hakui_man
張鈴偲 主任
現職
高雄長庚兒童過敏免疫科科主任
學歷
長庚大學醫學系畢業
長庚大學臨床醫學研究所碩士畢業
經歷
兒童一般醫學科主治醫師
長庚兒童風濕免疫過敏科總醫師
長庚兒童醫醫院住院醫師
高雄長庚兒童過敏免疫科科主任
高雄長庚醫院助理教授
學會與認證
兒童風濕過敏免疫學會專科醫師與指導醫師
中華民國免疫學會專科醫師兒科專科醫師兒科與指導醫師
台灣過敏氣喘暨臨床免疫醫學會專科醫師委員會委員
中華川崎症關懷協會理事
專長
一般兒科學
過敏氣喘
鼻炎
異位性皮膚炎
臨床免疫學
兒童自發性關節炎
紫斑症
川崎症等兒童風濕疾病
論文及研究
  1. Blood Mercury Levels in Children with Kawasaki Disease and Disease Outcome.
    Chang LS, Yan JH, Li JY, Yeter DD, Huang YH, Guo MM, Lo MH, Kuo HC.
    Int J Environ Res Public Health. 2020 May 25;17(10):3726.
  2. Clinical Characteristics for Differentiating Febrile Children With Suspected Kawasaki Disease Diagnosis.
    Yan JH, Chang LS, Lin YJ, Guo MM, Huang YH, Kuo HC.
    Front Pediatr. 2020 May 5;8:221.
  3. Epigenetic Regulation of Macrophage Marker Expression Profiles in Kawasaki Disease.
    Guo MM, Chang LS, Huang YH, Wang FS, Kuo HC.
    Front Pediatr. 2020 Apr 3;8:129.
  4. Low FCMR mRNA expression in leukocytes of patients with Kawasaki disease six months after disease onset.
    Chang LS, Guo MM, Yan JH, Huang YH, Lo MH, Kuo HC.
    Pediatr Allergy Immunol. 2020 Feb 19.
  5. The role of corticosteroids in the treatment of Kawasaki disease.
    Chang LS, Kuo HC.
    Expert Rev Anti Infect Ther. 2020 Feb;18(2):155-164.
  6. dentification of increased expression of activating Fc receptors and novel findings regarding distinct IgE and IgM receptors in Kawasaki disease.
    Chang LS, Ming-Huey Guo M, Lo MH, Kuo HC.
    Pediatr Res. 2019 Dec 9. doi: 10.1038/s41390-019-0707-y. Online ahead of print.
    PMID: 31816620
  7. Successful treatment in a child with enthesitis-related arthritis involving the sternoclavicular joint: a case report.
    Huang PY, Chang LS, Guo MM, Kuo HC.
    BMC Pediatr. 2019 Oct 23;19(1):373.
  8. Association between maternal age and outcomes in Kawasaki disease patients.
    Huang WD, Lin YT, Tsai ZY, Chang LS, Liu SF, Lin YJ, Kuo HC.
    Pediatr Rheumatol Online J. 2019 Jul 19;17(1):46.
  9. Decreased DNA methyltransferases expression is associated with coronary artery lesion formation in Kawasaki disease.
    Huang YH, Chen KD, Lo MH, Cai XY, Chang LS, Kuo YH, Huang WD, Kuo HC.
    Int J Med Sci. 2019 Apr 25;16(4):576-582.
  10. Decreased incidence of glaucoma in children with asthma using inhaled corticosteroid: a cohort study.
    Chang LS, Lee HC, Tsai YC, Shen LS, Li CL, Liu SF, Kuo HC.
    Oncotarget. 2017 Nov 1;8(62):105463-105471. doi: 10.18632/oncotarget.22252. eCollection 2017 Dec 1.
  11. CYP2E1 Gene Polymorphisms Related to the Formation of Coronary Artery Lesions in Kawasaki Disease.
    Chang LS, Hsu YW, Lu CC, Lo MH, Hsieh KS, Li SC, Chang WC, Kuo HC.
    Pediatr Infect Dis J. 2017 Nov;36(11):1039-1043.
  12. l-Arginine-Dependent Epigenetic Regulation of Interleukin-10, but Not Transforming Growth Factor-β, Production by Neonatal Regulatory T Lymphocytes.
    Yu HR, Tsai CC, Chang LS, Huang HC, Cheng HH, Wang JY, Sheen JM, Kuo HC, Hsieh KS, Huang YH, Yang KD, Hsu TY.
    Front Immunol. 2017 Apr 25;8:487.
  13. The effect of FcγRIIA and FcγRIIB on coronary artery lesion formation and intravenous immunoglobulin treatment responses in children with Kawasaki disease.
    Chang LS, Lo MH, Li SC, Yang MY, Hsieh KS, Kuo HC.
    Oncotarget. 2017 Jan 10;8(2):2044-2052.
  14. Correlation of pandemic (H1N1) 2009 viral load with disease severity and prolonged viral shedding in children.
    Li CC, Wang L, Eng HL, You HL, Chang LS, Tang KS, Lin YJ, Kuo HC, Lee IK, Liu JW, Huang EY, Yang KD.
    Emerg Infect Dis. 2010 Aug;16(8):1265-72
  15. Acute lymphoblastic leukemia presented as severe jaundice and hyperferritinemia: a case report.
    Chang LS, Yu HR, Chen YC, Yeah ST, Tiao MM, Hsiao CC, Sheen JM.
    J Pediatr Hematol Oncol. 2011 Apr;33(3):e117-9
  16. Risk factors for mortality of pediatric patients without underlying diseases.
    Chang LS, Kuo HC, Wu CC, Yu HR, Wang L, Chang HW, Yang KD.
    Pediatr Neonatol. 2011 Feb;52(1):34-7. doi: 10.1016/j.pedneo.2010.12.007.
  17. Etanercept treatment for children with refractory juvenile idiopathic arthritis.
    Kuo HC, Yu HR, Wu CC, Chang LS, Yang KD.
    J Microbiol Immunol Infect. 2011 Jan 13;44(1):52-56
  18. Higher levels of soluble Fas ligand and transforming growth factor-β after omalizumab treatment: a case report.
    Kao SL, Yu HR, Kuo HC, Tsui KY, Wu CC, Chang LS, Liang CD, Chung YH, Yang KD.
    J Microbiol Immunol Infect. 2012 Feb;45(1):69-71. doi: 10.1016/j.jmii.2011.12.026. Epub 2012 Jan 13.
  19. A surveillance system to reduce transmission of pandemic H1N1 (2009) influenza in a 2600-bed medical center.
    Chu TP, Li CC, Wang L, Hsu LW, Eng HL, You HL, Liu JW, Wei CC, Chang LS, Lee IK, Yang KD.
    PLoS One. 2012;7(3):e32731. doi: 10.1371/journal.pone.0032731. Epub 2012 Mar 13.
聯繫方式
irasutoya_clipborad_hakui_man
郭和昌 醫師
現職
高雄長庚醫院兒童內科部教授
長庚大學醫學院教授
川崎症中心主任
中華川崎症關懷協會理事長
美國過敏免疫學院國際院士FAAAAI
學歷
國立陽明大學醫學系
長庚大學臨床醫學研究所博士
經歷
高雄長庚兒童內科部主治醫師
高雄長庚兒童內科部住院醫師
高雄長庚兒童風濕過敏免疫科研究員
著作
  1. 兒童發燒五天竟導致心臟病: 不可不知的川崎症 (Oct 2011 1st version, 郭和昌 醫師主編, 麗文文化事業股份有限公司出版, ISBN 13/9789577484451, SBN 10/957748445X, EAN/9789577484451)
  2. 郭和昌醫師告訴你: 孩子高燒要當心, 別讓川崎症傷了寶貝的心臟作者(郭和昌 出版社/貓頭鷹出版社/出版日期2013/11/05; ISBN 13/9789862621790)
  3. 國際過敏免疫專家告訴你：小兒過敏指數這樣算、那樣治療與預防 (作者: 郭和昌 出版社: 貓頭鷹; 出版日：2014/4/17; ISBN：9789862622032)
  4. 川崎症口袋寶貝書，郭和昌/主編；麗文文化事業股份有限公司 出版日期:2017/02/25 , ISBN 13/9789577489173。ISBN 10/9577489176；EAN/9789577489173
專長
一般兒科學
兒童過敏氣喘免疫風濕科
鼻炎
異位性皮膚炎
臨床免疫學
兒童自發性關節炎
紫斑症
川崎症等兒童風濕疾病
臨床醫學
論文及期刊發表
共182篇，其中100篇川崎症相關
Associate Editor:
  1. Frontiers in Immunology (SCI IF: 5.085)
  2. Frontiers in Pediatrics (SCI IF: 2.63)
  3. BMC Pediatrics (SCI IF: 1.98)
Editor: Plosone (SCI IF: 2.7)

論文(since 2019)
  1. Huang YH, Chen KD, Lo MH, Cai XY, Kuo HC.* Decreased Steroid Hormone Receptor NR4A2 Expression in Kawasaki Disease Before IVIG Treatment. Front Pediatr. 2019 Feb 4;7:7. (corresponding author) (2018, SCI IF:2.349, ranking: 33/125, Q2 in PEDIATRICS),被引用2次。
  2. Kuo HC, Lo CC, Wang YD, Wu JD, Lin BS. Spectrogram for Childhood Asthma Detection and Analysis. Allergy. 2019 Sep;74(9):1783-1786. (2018, SCI IF:6.771, ranking: 25/158, Q1 in IMMUNOLOGY)
  3. Huang YH, Lo MH, Cai XY, Liu SF, Kuo HC.* Increase expression of CD177 in Kawasaki disease. Pediatr Rheumatol Online J. 2019 Apr 3;17(1):13. (2018, SCI IF:2.673, ranking: 19/31, Q3 in RHEUMATOLOGY) ,被引用1次。
  4. Huang YH, Lin KM, Ho SC, Yan JH, Lo MH, Kuo HC. Increased Incidence of Kawasaki Disease in Taiwan in Recent Years: A 15 Years Nationwide Population-Based Cohort Study. Front Pediatr. 2019 Mar 29;7:121. (2018, SCI IF:2.349, ranking: 33/125, Q2 in PEDIATRICS) ,被引用7次。
  5. Huang YH, Chen KD, Lo MH, Cai XY, Chang LS, Kuo YH, Huang WD, Kuo HC*. Decreased DNA methyltransferases expression is associated with coronary artery lesion formation in Kawasaki disease. Int J Med Sci. 2019 Apr 25;16(4):576-582. (2018, SCI IF:2.333, ranking: 53/160, Q2 in MEDICINE, GENERAL & INTERNAL) ,被引用6次。
  6. Wang LJ, Yang CY, Chou WJ, Lee MJ, Chou MC, Kuo HC, Yeh YM, Lee SY, Huang LH, Li SC. Gut microbiota and dietary patterns in children with attention-deficit/hyperactivity disorder. Eur Child Adolesc Psychiatry. 2019 May 22. doi:10.1007/s00787-019-01352-2. (2018, SCI IF: 3.740, ranking: 42/146, Q1 in PSYCHIATRY) ,被引用7次。
  7. Wu CC, Hsu TY, Chang JC, Ou CY, Kuo HC, Liu CA, Wang CL, Chuang H, Chen CP, Yang KD. Paternal Tobacco Smoke Correlated to Offspring Asthma and Prenatal Epigenetic Programming. Front Genet. 2019 May 31;10:471. (2018, SCI IF: 3.517, ranking: 56/174, Q2 in GENETICS & HEREDITY) ,被引用2次。
  8. Wang LJ, Li SC, Kuo HC, Chou WJ, Lee MJ, Chou MC, Tseng HH, Hsu CF, Lee SY, Lin WC. Gray matter volume and microRNA levels in patients with attention-deficit/hyperactivity disorder. Eur Arch Psychiatry Clin Neurosci. 2019 Jun 25. doi: 10.1007/s00406-019-01032-x. (2018, SCI IF: 3.192, ranking: 52/146, Q2 in PSYCHIATRY) ,被引用2次。
  9. Kuo HC, Pan CT, Huang YH, Huang FC, Lin YS, Li SC, Huang LH. Global Investigation of Immune Repertoire Suggests Kawasaki Disease Has Infectious Cause. Circ J. 2019 Sep 25;83(10):2070-2078. (2018, SCI IF: 3.025, ranking: 55/136, Q2 in CARDIAC & CARDIOVASCULAR SYSTEM) ,被引用1次。
  10. Huang WD, Lin YT, Tsai ZY, Chang LS, Liu SF, Lin YJ, Kuo HC*. Association between maternal age and outcomes in Kawasaki disease patients. Pediatr Rheumatol Online J. 2019 Jul 19;17(1):46. (2018, SCI IF:2.673, ranking: 19/31, Q3 in RHEUMATOLOGY)
  11. Huang PY, Chang LS, Guo MM, Kuo HC. Successful treatment in a child with enthesitis-related arthritis involving the sternoclavicular joint: a case report. BMC Pediatr. 2019 Oct 23;19(1):373. doi: 10.1186/s12887-019-1770-6. (2018, SCI IF:1.983, ranking: 56/125, Q2 in PEDIATRICS)
  12. Wang LJ, Lee SY, Tsai CS, Lee MJ, Chou MC, Kuo HC, Chou WJ. Validity of Visual and Auditory Attention Tests for Detecting ADHD. J Atten Disord. 2019 Nov 28:1087054719887433. (2018, SCI IF: 3.656, ranking: 43/146, Q2 in PSYCHIATRY) ,被引用1次。
  13. Chang LS, Ming-Huey Guo M, Lo MH, Kuo HC*. Identification of increased expression of activating Fc receptors and novel findings regarding distinct IgE and IgM receptors in Kawasaki disease. Pediatr Res. 2019 Dec 9. doi: 10.1038/s41390-019-0707-y. (2018, SCI IF:2.880, ranking: 18/125, Q1 in PEDIATRICS) ,被引用2次。
Year 2020
  1. Chang LS, Kuo HC*. The role of corticosteroids in the treatment of Kawasaki disease. Expert Rev Anti Infect Ther. 2020 Feb;18(2):155-164. (2018, SCI IF:3.090, ranking: 93/267, Q2 in PHARMACOLOGY & PHARMACY)
  2. Chang SF, Liu SF, Chen CN, Kuo HC*. Serum IP-10 and IL-17 from Kawasaki disease patients induce calcification-related genes and proteins in human coronary artery smooth muscle cells in vitro. Cell Biosci. 2020 Mar 11;10:36. doi: 10.1186/s13578-020-00400-8. eCollection 2020. (2018, SCI IF:3.355, ranking: 124/299, Q2 in BIOCHEMISTRY & MOLECULAR BIOLOGY) ,被引用1次。
  3. Li CL, Lin MH, Chen PS, Tsai YC, Shen LS, Kuo HC, Liu SF. Using the BODE Index and Comorbidities to Predict Health Utilization Resources in Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2020 Feb 19;15:389-395. doi: 10.2147/COPD.S234363. eCollection 2020. (2018, SCI IF:3.274, ranking: 23/63, Q2 in RESPIRATORY SYSTEM)
  4. Chang LS, Guo MM, Yan JH, Huang YH, Lo MH, Kuo HC*. Low FCMR mRNA expression in leukocytes of patients with Kawasaki disease six months after disease onset. Pediatr Allergy Immunol. 2020 Feb 19. doi: 10.1111/pai.13235. (2009, SCI IF: 2.676, ranking 67/128,Q3 in IMMUNOLOGY),被引用1次。
  5. Liu SF, Kuo NY, Kuo HC. Comparison of the Characteristics and Outcomes of Coronavirus Disease 2019 in Different Types of Family Infections in Taiwan. J Clin Med. 2020 May 19;9(5):E1527. (2018, SCI IF:, ranking: 15/160, Q1 in MEDICINE, GENERAL & INTERNAL)
  6. Yan JH, Chang LS, Lin YJ, Guo MM, Huang YH, Kuo HC*. Clinical Characteristics for Differentiating Febrile Children With Suspected Kawasaki Disease Diagnosis. Front Pediatr. 2020 May 5;8:221. doi: 10.3389/fped.2020.00221. eCollection 2020. (2018, SCI IF:2.349, ranking: 33/125, Q2 in PEDIATRICS)
  7. Tai IH, Wu PL, Guo MM, Lee J, Chu CH, Hsieh KS, Kuo HC*. Prognostic nutrition index as a predictor of coronary artery aneurysm in Kawasaki Disease. BMC Pediatr. 2020 May 11;20(1):203. doi: 10.1186/s12887-020-02111-y. (2018, SCI IF:1.983, ranking: 56/125, Q2 in PEDIATRICS)
  8. Liu SF, Kuo NY, Kuo HC. Three Taiwan's domestic family cluster infections of coronavirus disease 2019. J Med Virol. 2020 Apr 28. doi: 10.1002/jmv.25949. (2018, SCI IF:2.049, ranking: 26/36, Q3 in VIROLOGY)
  9. Guo MM, Chang LS, Huang YH, Wang FS, Kuo HC*. Epigenetic Regulation of Macrophage Marker Expression Profiles in Kawasaki Disease. Front Pediatr. 2020 Apr 3;8:129. doi: 10.3389/fped.2020.00129. eCollection 2020. (2018, SCI IF:2.349, ranking: 33/125, Q2 in PEDIATRICS)
  10. Chang LS, Yan JH, Li JY, Yeter DD, Huang YH, Guo MM, Lo MH, Kuo HC*. Blood Mercury Levels in Children with Kawasaki Disease and Disease Outcome. Int J Environ Res Public Health. 2020 May 25;17(10):E3726. (2018, SCI IF:2.468, ranking: 112/251, Q2 in ENVIRONMENTAL SCIENCES)
聯繫方式
irasutoya_clipborad_hakui_man
郭明慧 醫師
現職
高雄長庚兒童過敏免疫風濕科主治醫師
學歷
台灣大學醫學系
經歷
高雄長庚小兒科住院醫師
高雄長庚兒童過敏免疫風濕科研究員
學會與認證
台灣兒科醫學會 專科執照
中華免疫學會 專科執照
台灣兒童免疫學會 專科執照
歐洲氣喘過敏免疫學會會員(EAACI)
專長
一般兒科學
過敏氣喘
鼻炎
異位性皮膚炎
臨床免疫學
兒童自發性關節炎
紫斑症
川崎症等兒童風濕疾病
聯繫方式
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高雄長庚 兒童內科部
高雄長庚 兒童內科 (院區代碼407)
地址: 高雄市鳥松區大埤路123號 兒童內科部
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本頁最後更新日期: 20220831
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