李秋美
林靖麒
林科名
王文科
謝清川
陳肇寅
郭昶甫
曾啟權
江博暉
林宜君
楊昭輝
林坤成
洪裕強
林志哲
莊文郁
莊蕙青
林素珍
張中明
舒竹青
黃幸宜
郭敏玲
王永樑
羅時成
中野敏明
陳芳馨
周百謙
張國軒
黃冠穎
陳品元
韓仕聰
楊皇煜
賴彬卿
羅淑芬
塗昆樺
許瑞旭
賴振宏
李威震
詹昆明
林承弘
林柏宏
黃璟隆
陳力振
林思偕
劉錦棠
林意旋
沈建忠
吳黃平
胡瀞之
吳宗翰
葉光揚
吳詹永嬌
曾文逸
蔡文彬
廖穗綾
蘇冠文
林胤谷
張心寧
黃澤宏
葉沅杰
李志宏
郭和昌
黃聰龍
楊賢鴻
賴信志
林政道
李文益
陳基益
黃毓惠
沈家瑞
方嘉佑
林怡廷
顧正崙
林錫賢
邱健泰
黃景泰
張文震
邱志勇
傅崇安
林俊彥
周開平
吳承宇
吳庭榕
林展宇
楊智偉
李立夫
陳濘宏
Rajendra Prasad Janapatla
陳奇良
王燕玲
魏福全
陳澤卿
鐘文宏
鍾福財
單位: 長庚大學
現職: 微生物及免疫學科 教授
電話: 03-2118800 分機: 3321 傳真: 03-211846
E-mail: hhlin@mail.cgu.edu.tw
研究領域:
- 免疫
- 醫學之生化及分子生物
研究成果:
1. I have generated F4/80 knock-out mice to characterize the biological functions of the molecule in vivo.
2. I am actively involved in identification of new members of the adhesion-GPCR family and the elucidation of the functions of these receptors including their specific expression patterns and the identification of their cellular ligands, etc.
3. Another area of interest in the post-translational modification of the adhesion-GPCR receptor, which involves a conserved proteolytic cleavage process and its functional role.
工作經歷:
2011/8–present Professor/Laboratory Head, Laboratory of Molecular Immunology, Department of Microbiology and Immunology, Chang Gung University, Taiwan.
2007/8–2011/7 Associate Professor/Laboratory Head, Laboratory of Molecular Immunology, Department of Microbiology and Immunology, Chang Gung University, Taiwan.
2004/12–2007/7 Assistant Professor/Laboratory Head, Laboratory of Molecular Immunology, Department of Microbiology and Immunology, Chang Gung University, Taiwan.
2000/7–2004/11 Group leader/Senior Research Fellow, Sir William Dunn School of Pathology, the University of Oxford, UK.
學歷:
1992/8 – 1997/12 Ph.D., Oak Ridge Graduate School of Biomedical Sciences, University of Tennessee – Knoxville, TN, U.S.A.
殊榮:
- 1992-1997 UT-Oak Ridge Graduate School of Biomedical Sciences, Pre-doctoral Fellowships
- 1997 University of Tennessee - Knoxville
Chancellor’s Citation for Extraordinary Professional Promise
(The highest honor for a graduate student in the University) - 1998-2000 Wellcome Trust Cardiovascular Research Initiative Research Fellowship, U.K.
- 2000-2002 Celltech Ltd. Senior Research Fellowship, U.K.
- 2002-2004 British Heart Foundation Research Fellowship, UK
- 長庚大學99-101年度國科會補助大專校院獎勵特殊優秀人才獎
- 2012-Present Board Member, Adhesion-GPCR Consortium
代表論文:
1. N.-Y. Chiang, C.-C. Hsiao, Y.-S. Huang, H.-Y. Chen, I-J. Hsieh, G.-W. Chang, H.-H. Lin* 2011 Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms.J. Biol. Chem. 286(16): 14215-14225.
2. Y.-M. Peng, Martijn D.B. van de Garde, K.-F. Cheng, P.A. Baars, R.A.W. van Lier, C.R. Mackay, H.-H. Lin*, and J. Hamann* 2011 Specific expression of GPR56 by human cytotoxic lymphocytes. J. Leukoc. Biol. 90:735-740
3. Y.-S. Huang, N.-Y. Chiang, C.-H. Hu, C.-C. Hsiao, K.-F. Cheng, W.-P. Tsai, Simon Yona, Martin Stacey, Siamon Gordon, G.-W. Chang* and H.-H. Lin* 2012 Activation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains. Mol. Cell. Biol. 32(8): 1408-1420
4. W.-Y. Tseng, Y.-S. Huang, N.-Y. Chiang, Y.-P. Chou, Y.-J. Jan Wu, S.-F. Luo, C.-F. Kuo, K.-M. Lin, andH.-H. Lin* 2013 Increased soluble CD4 in serum of rheumatoid arthritis patients is generated by matrix metalloproteinase (MMP)-like proteinases. PLoS ONE 8(5): e63963.
5. C.-C. Hsiao&, W.-C. Wang&, W.-L. Kuo, H.-Y. Chen, T.-C. Chen, J. Hamann, H.-H. Lin* 2014 CD97 inhibits cell migration in human fibrosarcoma cells by modulating TIMP-2/MT1-MMP/MMP-2 activity. FEBS Journal 281(21):4878-91.
所有論文著作一覽表