Page 43 - 林口醫研部2022三月電子報

‣研究目的背景

Psoriasis, venous thromboembolism (VTE), and peripheral vascular

disease (PVD) share similar mechanisms involving chronic inflammation.

However, the associations between psoriasis and VTE or PVD are unclear.

‣研究發現與應用

This systematic review and meta-analysis found an increased risk for

incident VTE and PVD among patients with psoriatic disease. Typical

presentations of VTE or PVD should not be overlooked in patients with

psoriasis. Risk factors, such as obesity, physical inactivity, smoking, and

varicose veins, should be identified and treated in patients with psoriasis,

and medications like hormone-related therapies should be prescribed with

caution.

‣背景

乾癬是一種發炎性皮膚疾病，過去研究顯示乾癬病人罹患心血管疾

病的風險增加，其機轉主要以慢性血管發炎為主。乾癬與靜脈血栓(VTE)

與周邊血管疾病(PVD)的相關性被報導過，目前的乾癬指引中並未針對

VTE或PVD的預防或治療措施加以闡述。

Department of Medical Research & Development , Linkou Newsletter 43