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基因醫學核心實驗室
Genomic Medicine Core Laboratory

 


 

 

 

 

 

 

 

 

 
                                 研 究 成 果  
  • Hsu CN, Chan JYH, Wu KLH, Yu HR, Lee WC, Hou CY, Tain YL; Altered Gut Microbiota and Its Metabolites in Hypertension of Developmental Origins: Exploring Differences between Fructose and Antibiotics Exposure.Int. J. Mol. Sci. 2021, 22, 2674. doi: 10.3390/ijms22052674
  • Chen CB, Kuo KL, Wang CW, Lu CW, Chung-Yee Hui R, Lu KL, Chang WC, Chen WT,Yun F, Teng YC, Lee HE, Lin JY, Ho HC, Chi MH, Yu-Wei Lin Y, Chang CJ, Lin Y Jr,Ku CL, Hung SI, Chang YC, Chung WH; Taiwan Severe Cutaneous Adverse ReactionConsortium. Detecting Lesional Granulysin Levels for Rapid Diagnosis ofCytotoxic T lymphocyte-Mediated Bullous Skin Disorders. J Allergy Clin ImmunolPract. 2020 Oct 8:S2213-2198(20)31098-9. doi: 10.1016/j.jaip.2020.09.048. Epubahead of print. PMID: 33039642.
  • Chen CB, Chen YE, Chu MT, Wang CW, Chung-Yee Hui R, Lu CW, Hsiao YP, Chu CY,Chang MM, Man-Tung Cheung C, Cheng CY, Wang YW, Lin YJ, Chang CJ, Hung SI, ChungWH. The risk of anti-osteoporotic agent-induced severe cutaneous adverse drugreactions and their association with HLA. J Eur Acad Dermatol Venereol. 2020 Sep7. doi: 10.1111/jdv.16924. Epub ahead of print. PMID: 32896010.
  • Chen CB, Hsu TH, Chung-Yee Hui R, Lu CW, Chen WT, Chiang PH, Wang CW, ChuangSS, Yang JY, Yang SY, Chang SY, Hsiao YC, Kao KC, Hu HC, Wu TS, Hsu CW, Hui-KangMa D, Chen SY, Tian YC, Cheng CY, Chen CH, Chi MH, Wu MY, Liu RF, Wang CH, ChangYC, Lin JY, Ho HC, Yu-Wei Lin Y, Chang CJ, Lin YJ, Ku CL, Hung SI, Chung WH;Taiwan Severe Cutaneous Adverse Reaction Consortium. Disseminated intravascularcoagulation in Stevens-Johnson syndrome and toxic epidermal necrolysis. J AmAcad Dermatol. 2020 Aug 20:S0190-9622(20)32459-2. doi:10.1016/j.jaad.2020.08.065. Epub ahead of print. PMID: 32828861.
  • Wang CW, Tassaneeyakul W, Chen CB, Chen WT, Teng YC, Huang CY, Sukasem C, LuCW, Lee YS, Choon SE, Nakkam N, Hui RC, Huang YH, Chang YC, Lin YY, Chang CJ,Chiu TM, Chantratita W, Konyoung P, Lee CN, Klaewsongkram J, Rerkpattanapipat T,Amornpinyo W, Saksit N, Rerknimitr P, Huang YH, Lin SH, Hsu CK, Chan CC, Lin YJ,Hung SI, Chung WH; Taiwan/Asian Severe Cutaneous Adverse Reaction Consortium.Whole genome sequencing identifies genetic variants associated with co-trimoxazole hypersensitivity in Asians. J Allergy Clin Immunol. 2020 Aug10:S0091-6749(20)31109-X. doi: 10.1016/j.jaci.2020.08.003. Epub ahead of print.PMID: 32791162.
  • Chang WC, Hung SI, Carleton BC, Chung WH. An update on CYP2C9 polymorphismsand phenytoin metabolism: implications for adverse effects. Expert Opin DrugMetab Toxicol. 2020 Aug;16(8):723-734. doi: 10.1080/17425255.2020.1780209. Epub2020 Jul 16. PMID: 32510242.
  • Chiu CY, Chou HC, Chang LC, Fan WL, Dinh MCV, Kuo YL, Chung WH, Lai HC,Hsieh WP, Su SC. Integration of metagenomics-metabolomics reveals specificsignatures and functions of airway microbiota in mite-sensitized childhoodasthma. Allergy. 2020 Nov;75(11):2846-2857. doi: 10.1111/all.14438. Epub 2020Jul 13. PMID: 32506557.
  • Chang CJ, Chen CB, Hung SI, Ji C, Chung WH. Pharmacogenetic Testing forPrevention of Severe Cutaneous Adverse Drug Reactions. Front Pharmacol. 2020 Jul2;11:969. doi: 10.3389/fphar.2020.00969. PMID: 32714190; PMCID: PMC7346738.
  • Ma KS, Wei JC, Chung WH. Correspondence to 'Hypersensitivity reactions withallopurinol and febuxostat: a study using the Medicare claims data'. Ann RheumDis. 2020 Jun 19:annrheumdis-2020-218090. doi: 10.1136/annrheumdis-2020-218090.Epub ahead of print. PMID: 32561605.
  • Wu IW, Gao SS, Chou HC, Yang HY, Chang LC, Kuo YL, Dinh MCV, Chung WH, YangCW, Lai HC, Hsieh WP, Su SC. Integrative metagenomic and metabolomic analysesreveal severity-specific signatures of gut microbiota in chronic kidney disease.Theranostics. 2020 Apr 6;10(12):5398-5411. doi: 10.7150/thno.41725. PMID:32373220; PMCID: PMC7196299.
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