服務項目

醫療服務

臨床研究

1. 川崎症團隊累積至今已發表超過80篇文獻，並持續增加中。
2. 全亞洲排名第一之川崎症專家為高雄長庚郭和昌醫師，而前二十位有三位是我們高雄長庚川崎症團隊成員，分別為郭和昌醫師(第一名)、于鴻仁醫師(第十六名)、黃瀛賢醫師(第十八名)。
3. 2017年於香港舉辦之亞洲兒科醫學會議(ASPR)，本團隊總共有七位參與，其中郭明慧醫師更榮獲最佳口頭報告者。
4. 2018年將於日本橫濱舉行之川崎症國際會議，我們團隊總共有16篇摘要被接受。張貼海報共15篇，當中有2篇被邀請做口頭簡述，而正式口頭報告為1篇。

宣導川崎症

1. 自創三組LINE貼圖且截至2018年4月已累積超過5萬5千次使用次數，並持續增加中。
2. 從2016年至2017年陸續邀請到TVBS公益大使趙立一同宣導川崎症。
3. 2017年邀請到世界羽球球后戴資穎為我們川崎症中心拍攝國語版與台語版的宣導短片。
4. 2018年旅美球星王建民受邀參與高雄長庚兒童病友會活動，並一同宣導血友病與川崎症。
5. 於2017年接受民視異言堂節目專訪川崎症，在我們粉絲頁上創造出高達兩百二十八萬次的觀看次數、超過四百三十萬次的觸擊率、獲得超過一萬一千個讚、被轉貼超過三萬五千多次分享以及觀看後民眾主動留言詢問將近兩千則。
6. 目前已接受超過20場新聞記者採訪川崎症相關議題。 衛教場次累積至今已達358場。

團隊顧問

團隊成員

治療特色

主要特色

1. 發明全球首創分子診斷方式協助早日診斷
2. 精準治療提升成功治療率，經驗分享全球
3. 領先全球，動脈瘤成功治療經驗超過10例

治療經驗

1. 已完成超過1,000例球蛋白治療，治療成功率高達92％ （球蛋白治療僅一次，美國85％，日本87％）
2. 冠狀動脈瘤幾乎是0％ （至少半年追蹤）
3. 0％死亡率
4. 隨訪追蹤經驗超過3,000例
5. 動脈瘤成功治療經驗超過10例
6. 最成功個案原本血管內竟寬度 10.5mm 改善半年至 2.8mm

出版書籍

1. 兒童發燒五天竟導致心臟病: 不可不知的川崎症 (Oct 2011 1st version, 郭和昌 醫師主編, 麗文文化事業股份有限公司出版, ISBN 13/9789577484451, SBN 10/957748445X, EAN/9789577484451)
2. Ho-Chang Kuo, Wei-Chiao Chang; " Chapter10: Cardiovascular lesions of Kawasaki disease: From genetic study to clinical management", Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues - From Molecules to Humans. ISBN 978-953-51-0679-1, Hard cover, 390 pages, Publisher: InTech, Published: July 18, 2012.

Chronic Inflammation: Causes, Treatment Options and Role in Disease. Editors: Wei-Chiao Chang and Wen-Chang Chang. Chapter 5. Chronic Inflammation of Kawasaki Disease. (Ying-Hsien Huang and Ho-Chang Kuo) pp. 77-96. ISBN: 978-1-62808-094-0.
Chronic Inflammation: Causes, Treatment Options and Role in Disease. Editors: Wei-Chiao Chang and Wen-Chang Chang. Chapter 10. Chronic Inflammation of Biliary Atresia (Ho-Chang Kuo, Jiin-Haur Chuang and Ying-Hsien Huang) pp. 157-170. ISBN: 978-1-62808-094-0.
Compendium of Inflammatory Diseases, Editors: Michael Parnham, ISBN: 978-3-0348-0620-6. (Online) Title: Kawasaki Disease. DOI: 10.1007/978-3-0348-0620-6_96-1, Publisher: Springer Basel
郭和昌醫師告訴你: 孩子高燒要當心, 別讓川崎症傷了寶貝的心臟，(作者: 郭和昌 出版社/貓頭鷹出版社/出版日期2013/11/05; ISBN 13/9789862621790)
國際過敏免疫專家告訴你：小兒過敏指數這樣算、那樣治療與預防 (作者: 郭和昌 出版社: 貓頭鷹; 出版日：2014/4/17; ISBN：9789862622032)
川崎症口袋寶貝書，郭和昌/主編；麗文文化事業股份有限公司 出版日期:2017/02/25 , ISBN 13/9789577489173。ISBN 10/9577489176；EAN/9789577489173
由中華川崎症關懷協會所製作之川崎寶寶Line貼圖40張，Copyright ©Kawasaki Disease Center, 2017/03 上架 (Kawasaki Disease Line stickers)

專利

代表論文

1. Yi-Ching Lee, Ho-Chang Kuo, Jeng-Sheng Chang, Luan-Yin Chang, Li-Min Huang, Ming-Ren Chen, Chi-Di Liang, Hsin Chi, Fu-Yuan Huang, Meng-Luen Lee, Yhu-Chering Huang, Betau Hwang, Nan-Chang Chiu, Kao-Pin Huang, Pi-Chang Lee, Li-Ching Chang, Yi-Min Liu, Ying-Ju Chen, Chien-Hsiun Chen, Taiwan Pediatric ID Alliance , Yuan-Tsong Chen, Fuu-Jen Tsai, Jer-Yuarn Wu. Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. Nature Genetics 2012 Mar 25;44(5):522-5. (Co-1st author) (2016, SCI IF: 27.959, ranking 2/166, Q1 in GENETICS & HEREDITY),
2. I-Chun Lin, Jau-Ling Suen, Shau-Ku Huang, Shun-Chen Huang, Hsin-Chun Huang, Ho-Chang Kuo, Chi-Chen Wei, Feng-Shen Wang, Hong-Ren Yu, Kuender D. Yang. Dectin-1/Syk signaling is involved in Lactobacillus casei cell wall extract-induced mouse model of Kawasaki disease. Immunobiology 2013 Feb;218(2):201-12. (2016, SCI IF:2.720, ranking: 87/150, Q3 in Immunology)

Ying-Jui Lin, I-Chun Lin, Hong-Ren Yu, Hsuan-Chang Kuo, Kuender D. Yang, Wei-Chiao Chang, Chi-Di Liang, Shih-Feng Liu, Ho-Chang Kuo*. Tricuspid Regurgitation in Acute Phase of Kawasaki Disease Associated With Intensive Care Unit Admission. Pediatr Cardiol. 2013 Feb;34(2):250-5. (corresponding author*,2016, SCI IF: 1.688, ranking 89/126, Q3 in CARDIAC & CARDIOVASCULAR SYSYEM), 被引用5次。
Yu-Wen Hsu, Hsu-Chen Chien, Chi-Cheng Liang, Kuender D. Yang, Wei-Pin Chang, Ho-Chang Kuo*, Wei-Chiao Chang. Stromal Interaction Molecule 1 Polymorphisms are Associated with Coronary Artery Dilation but not with Aneurysm Formation in Patients with Kawasaki Disease. Journal of Experimental and Clinical Medicine. (corresponding author*)
Ho-Chang Kuo, Wei-Chiao Chang, Kuender D Yang, Hong-Ren Yu, Chih-Lu Wang, Shu-Chen Ho, Chun-Yuh Yang. Kawasaki disease and subsequent risk of allergic diseases: a population-based matched cohort study. BMC Pediatrics 2013 Mar 23;13:38. (2016, SCI IF:2.071, ranking 43/121, Q2 in Pediatrics)
Chiu-Ping Lee , Ying-Hsien Huang , Yu-Wen Hsu , Kuender D. Yang , Hsu-Chen Chien , Hong-Ren Yu , Ya-Ling Yang , Chih-Lu Wang , Wei-Chiao Chang, Ho-Chang Kuo*. TARC/CCL17 Gene Polymorphisms and Expression Associated with Susceptibility and the Formation of Coronary Artery Aneurysms in Kawasaki Disease. Pediatr Res. 2013 Nov;74(5):545-51. (2016, SCI IF:2.882, ranking 17/121, Q1 in Pediatrics) (corresponding author*)
Ho-Chang Kuo, Yu-Wen Hsu, Chung-Min Wu, Shawn Hsiang-Yin Chen, Kuo-Sheng Hung, Wei-Pin Chang, Kuender D. Yang, Kai-Sheng Hsieh, Wei-Chiao Chen, Yoshihiro Onouchi, and Wei-Chiao Chang. A Replication Study for Association of ITPKC and CASP3 Two-locus analysis in IVIG unresponsiveness and coronary artery lesion in Kawasaki disease. PLoS One. 2013 Jul 24;8(7):e69685.(2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)
Deniz Yeter, Richard Deth, Ho-Chang Kuo*. Mercury promotes catecholamines which potentiate mercurial autoimmunity and arterial vasodilation: implications for ITPKC susceptibility in Kawasaki syndrome. Korean Circ J. 2013 Sep;43(9):581-591. (corresponding author*) (2016, SCI IF:1.252, ranking: 104/126, Q4 in MU CARDIAC & CARDIOVASCULAR SYSYEM)。
Wei-Pin Chang, Shyh-JongWu, Wei-Chiao Chang, and Ho-Chang Kuo*. Population-Based Study of the Association between Urbanization and Kawasaki Disease in Taiwan. TheScientificWorldJournal 2013, Article ID 169365. (2010, SCI IF:1.524, ranking: 13/59, Q1 in MULTIDISCIPLINARY SCIENCES), (corresponding author*)
Mei-Chen Ou-Yang, Ho-Chang Kuo, I-Chun Lin, Jiunn-Ming Sheen, Fu-Chen Huang, Chih-Cheng Chen, Ying-Hsien Huang, Ying-Jui Lin, and Hong-Ren Yu. Plasma clusterin concentrations may predict resistance to intravenous immunoglobulin in patients with Kawasaki disease. TheScientific WorldJournal, 2013, Article ID 382523, (2010, SCI IF:1.524, ranking: 13/59, Q1 in MULTIDISCIPLINARY SCIENCES), (co-1st author*)
Chia-Jung Chang, Ho-Chang Kuo, Jong-Keuk Lee, Chiea Chuen Khor, Li-Ching Chang, Yi-Min Liu, Ying-Ju Chen, Young Mi Hong, Gi Young Jang, Martin L. Hibberd, Taco Kuijpers, David Burgner, Michael Levin, Jane Burns, Sonia Davila, International Kawasaki Disease Genetics Consortium, Korean Kawasaki Disease Genetics Consortium, Taiwan Kawasaki Disease Genetics Consortium, Yuan-Tsong Chen, Chien-Hsiun Chen, Jer-Yuarn Wu & Yi-Ching Lee. Replication of GWAS identification of Kawasaki disease susceptibility genes and a functional study affirm a role for BLK in disease susceptibility. PLoS One. 2013 Aug 30;8(8):e72037. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)。
Peng Yeong Woon, Wei Chiao Chang, Chi-Cheng Liang, Chun Hung Hsu, Sukhontip Klahan, Ying-Hsien Huang, Wei-Pin Chang and Ho-Chang Kuo.* Increased Risk of Atopic Dermatitis in Preschool Children with Kawasaki Disease: A Population-based Study in Taiwan. Evid Based Complement Alternat Med. 2013;2013:605123 (corresponding author*) (SCI) )
Kuo HC, Hsu YW, Lo MH, Huang YH, Chien SC, Chang WC. Single-Nucleotide Polymorphism rs7251246 in ITPKC Is Associated with Susceptibility and Coronary Artery Lesions in Kawasaki Disease. PLoS One. 2014 Mar 12;9(3):e91118. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)。
Ho-Chang Kuo, Chung-Min Wu, Wei-Pin Chang, Chun-Nan Kuo, Deniz Yeter, Chun-Yi Lin, Jei-Tsung Pai, Ying-Chen Chi, Chia-Hsien Lin, Liang-Jen Wang and Wei-Chiao Chang. Association between Kawasaki Disease and Autism: A Population-Based Study in Taiwan. Int. J. Environ. Res. Public Health 2014 11(4), 3705-3716. (2016, SCI IF:2.101, ranking: 101/229, Q2 in ENVIRONMENTAL SCIENCES)。
Wu TH, Kuo HC, Tain YL, Lin KM, Kuo HC, Chien SJ. Common carotid artery intima-media thickness is useful for diagnosis of the acute stage of Kawasaki disease. BMC Pediatr. 2014 Apr 10;14(1):98. (2016, SCI IF:2.071, ranking 43/121, Q2 in Pediatrics)
Huang YH, Tain YL, Lee CP, Kuo HC*. Asymmetric and Symmetric Dimethylarginine Are Associated with Coronary Artery Lesions in Kawasaki Disease. J Pediatr. 2014 Aug;165(2):295-9.. (corresponding author*) (SCI IF:4.122, ranking4/124, Q1 in Pediatrics)
Wan-Ning Tseng, Mao-Hung Lo, Kai-Sheng Hsieh, Wei-Chiao Chang, Ho-Chang Kuo*. IL-31 associated with coronary artery lesion formation in Kawasaki disease. PLoS One. 2014 Aug 14;9(8):e105195. PLoS One. 2013 Aug 30;8(8):e72037. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)
Ho-Chang Kuo, Ying-Hsien Huang, Shu-Chen Chien, Hong-Ren Yu, Kai-Sheng Hsieh, Yu-Wen Hsu, and Wei-Chiao Chang. Genetic variants of CD209 associated with Kawasaki disease susceptibility. PLoS One. 2014 Aug 22;9(8):e105236 (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)
Sandi C Lin, Wan-Lin Tseng, Mindy Ming-Huey Guo and Ho-Chang Kuo*. Etanercept as Rescue Therapy for Refractory Kawasaki Disease. Austin J Pediatr. 2014;1(2): 1010. (corresponding author*)
Kuo HC*, Chang JC, Kuo HC, Yu HR, Wang CL, Lee CP, Huang LT, Yang KD. Identification of an Association Between Genomic Hypomethylation of FCGR2A and Susceptibility to Kawasaki Disease and Intravenous Immunoglobulin Resistance by DNA Methylation Array. Arthritis Rheumatol. 2015 Mar;67(3):828-36. (2016, SCI IF:6.918, ranking: 3/30, Q1 in RHEUMATOLOGY)。
Mindy Ming-Huey Guo, Wan-Ning Tseng, Chia-Hung Ko, Hui-Mei Pan, Kai-Sheng Hsieh, Ho-Chang Kuo*. Th17- and Treg-related cytokine and mRNA expression are associated with acute and resolving Kawasaki disease. Allergy 2015 Mar;70(3):310-8. (2016, SCI IF:7.361, ranking: 20/150, Q1 in IMMUNOLOGY)。
Ko TM, Kuo HC, Chang JS, Chen SP, Liu YM, Chen HW, Tsai FJ, Lee YC, Chen CH, Wu JY, Chen YT. CXCL10/IP-10 is a Biomarker and Mediator for Kawasaki Disease. Circ Res. 2015 Feb 27;116(5):876-83. (co-1st author) (2016, SCI IF:13.965, ranking: 5/126, Q1 in IMM CARDIAC & CARDIOVASCULAR SYSTEMS)。
Kuo HC, Hsu YW, Wu MS, Woon PY, Wong HS, Tsai LJ, Lin RK, Klahan S, Hsieh KS, Chang WC. FCGR2A Promoter Methylation and Risks for Intravenous Immunoglobulin Treatment Responses in Kawasaki Disease. Mediators Inflamm. 2015;2015:564625. (2016, SCI IF:3.232, ranking: 94/189, Q2 in CELL BIOLOGY)。
Guo MM, Tseng WN, Ou CY, Hsu TY, Kuo HC*, Yang KD. Predictive factors of persistent infantile atopic dermatitis up to 6 years old in Taiwan: a prospective birth cohort study. Allergy. 2015 Nov;70(11):1477-84. (2016, SCI IF:7.361, ranking: 20/150, Q1 in IMMUNOLOGY)。 (corresponding author)
Kuo HC, Chang WC, Wang LJ, Li SC, Chang WP. Association of Attention deficit hyperactivity disorder and Kawasaki disease: a nationwide population-based cohort study. Epidemiol Psychiatr Sci. 2015 Sep 22:1-8. (2016, SCI IF:4.246, ranking: 16/139, Q1 in PSYCHIATRY)。
Ho-Chang Kuo*, Jen-Chieh Chang, Mindy Ming-Huey Guo, Kai-Sheng Hsieh, Deniz Yeter, Sung-Chou Li, Kuender D. Yang. Gene-gene associations with the susceptibility of Kawasaki disease and coronary artery lesions. PLoS One. 2015 Nov 30;10(11):e0143056. (1st and correspondence author) (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)。
Kuo H-C, Lo M-H, Hsieh K-S, Guo MM-H, Huang Y-H. High-Dose Aspirin Is Associated with Anemia and Does Not Confer Benefit to Disease Outcomes in Kawasaki Disease. PLoS ONE 2015, 10(12): e0144603. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)。
Yeter D, Portman MA, Aschner M, Farina M, Chan WC, Hsieh KS, Kuo HC.* Ethnic Kawasaki Disease Risk Associated with Blood Mercury and Cadmium in U.S. Children. Int J Environ Res Public Health. 2016 Jan 5;13(1). (SCI IF: 2.063, correspondence author) (2016, SCI IF:2.101, ranking: 101/229, Q2 in ENVIRONMENTAL SCIENCES)。
Tseng HC, Ho JC, Guo MM, Lo MH, Hsieh KS, Tsai WC, Kuo HC*, Lee CH. Bull's eye dermatoscopy pattern at bacillus Calmette-Guérin inoculation site correlates with systemic involvements in patients with Kawasaki disease. J Dermatol. 2016 Sep;43(9):1044-50. (SCI IF: 1.577, corresponding author) (2016, SCI IF:2.094, ranking: 26/63, Q2 in DERMATOLOGY)。
Kuo HC, Hsu YW, Wu MS, Chien SC, Liu SF, Chang WC. Intravenous immunoglobulin, pharmacogenomics, and Kawasaki disease. J Microbiol Immunol Infect. 2016 Feb;49(1):1-7. (invited review article) (2016, SCI IF:2.973, ranking:77/150, Q2 in IMMUNOLOGY),
Interferon-gamma Genetic Polymorphism and Expression in Kawasaki Disease. Huang YH, Hsu YW, Lu HF, Wong HS, Yu HR, Kuo HC, Huang FC, Chang WC, Kuo HC*. Medicine (Baltimore). 2016 Apr;95(17):e3501. ( corresponding author). (2016, SCI IF:1.803, ranking:58/154, Q2 in MEDICINE,GENERAL & INTERAL)。
Huang YH, Kuo HC, Huang FC, Yu HR, Hsieh KS, Yang YL, Sheen JM, Li SC, Kuo HC*. Hepcidin-Induced Iron Deficiency Is Related to Transient Anemia and Hypoferremia in Kawasaki Disease Patients. Int J Mol Sci. 2016 May 12;17(5). (corresponding author) (2016, SCI IF:3.226, ranking:116/286, Q2 in BIOCHEMISTRY & MOLECULAR BIOLOGY)。
Kuo HC, Li SC, Guo MM, Huang YH, Yu HR, Huang FC, Jiao F, Kuo HC, Andrade J, Chan WC. Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease. PLoS One. 2016 May 12;11(5):e0154943. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES),
Ho-Chang Kuo, Kai-Sheng Hsieh, Mindy Ming-Huey Guo, Ken-Pen Weng, Luo-Ping Ger, Wen-Ching Chan, Sung-Chou Li. Next generation sequencing identifies miRNA-based biomarker panel for Kawasaki disease. Journal of Allergy and Clinical Immunology. 2016 Oct;138(4):1227-1230. (2016, SCI IF:13.081, ranking: 6/150, Q1 in IMMUNOLOGY)。
Li SC, Chan WC, Huang YH, Guo MM, Yu HR, Huang FC, Kuo HC, Kuo HC*. Major methylation alterations on the CpG markers of inflammatory immune associated genes after IVIG treatment in Kawasaki disease. BMC Med Genomics. 2016 Aug 12;9 Suppl 1:37. (SCI IF: 3.13) (corresponding author). (2016, SCI IF:2.848, ranking: 73/166, Q2 in GENETICS & HEREDITY),
Kuo HC, Wang CL, Yang KD, Lo MH, Hsieh KS, Li SC, Huang YH. Plasma Prostaglandin E2 Levels Correlated with the Prevention of Intravenous Immunoglobulin Resistance and Coronary Artery Lesions Formation via CD40L in Kawasaki Disease. PLoS One. 2016 Aug 15;11(8):e0161265. (2016, SCI IF:2.806, ranking: 15/64, Q1 in MULTIDISCIPLINARY SCIENCES)。
Hong-Ren Yu, Ying-Hsien Huang, Hsing-Chun Kuo, Fu-Chen Huang, Hsin-Chun Huang, Sung-Chou Li, Kai-Sheng Hsieh, Ho-Chang Kuo*. Distinct expressions of immunoglobulin signal related molecules between human Kawasaki disease and BALB/c mice treated with Lactobacillus asei cell wall extract. Int J Clin Exp Med 2016;9(10):19502-19511. (corresponding author) (2016, SCI IF:1.069, ranking: 104/128, Q4 in MEDICINE, RESEARCH & EXPERIMENTAL)。
Chang LS, Lo MH, Li SC, Yang MY, Hsieh KS, Kuo HC*. The effect of FcγRIIA and FcγRIIB on coronary artery lesion formation and intravenous immunoglobulin treatment responses in children with Kawasaki disease. Oncotarget. 2017 Jan 10;8(2):2044-2052.. (corresponding author) (2016, SCI IF:5.168, ranking: 48/189, Q2 in CELL BIOLOGY)
Huang YH, Li SC, Huang LH, Chen PC, Lin YY, Lin CC, Kuo HC*. Identifying genetic hypomethylation and upregulation of toll-like receptors in Kawasaki disease. Oncotarget. 2017 Feb 14;8(7):11249-11258. (SCI IF:5.008, corresponding author) (2016, SCI IF:5.168, ranking: 48/189, Q2 in CELL BIOLOGY)
Huang FC, Kuo HC, Huang YH, Yu HR, Li SC, Kuo HC. Anti-inflammatory effect of resveratrol in human coronary arterial endothelial cells via induction of autophagy: implication for the treatment of Kawasaki disease. BMC Pharmacol Toxicol. 2017 Jan 9;18(1):3. (2016, SCI IF:2.288, ranking: 142/256, Q3 in PHARMACOOGY & PHARMACY)
Huang YH, Kuo HC*. Anemia in Kawasaki Disease: Hepcidin as a Potential Biomarker. Int J Mol Sci. 2017 Apr 12;18(4). (SCI IF: 3.215, invited review, corresponding author) (2016, SCI IF:3.226, ranking:116/286, Q2 in BIOCHEMISTRY & MOLECULAR BIOLOGY) 。
Huang YH, Yang KD, Hsu YW, Lu HF, Wong HS, Yu HR, Kuo HC, Huang FC, Lo MH, Hsieh KS, Chen SF, Chang WC, Kuo HC*. Correlation of HAMP gene polymorphisms and expression with the susceptibility and length of hospital stays in Taiwanese children with Kawasaki disease. Oncotarget. 2017 May 8;8(31):51859-51868. (corresponding author) (2016, SCI IF:5.168, ranking: 48/189, Q2 in CELL BIOLOGY)。
Kuo HC.* Preventing coronary artery lesions in Kawasaki disease. Biomed J. 2017 Jun;40(3):141-146. (invited review) (2016, SCI IF: 2.799, ranking: 111/190, Q3 in CELL BIOLOGY )。
Chang LS, Hsu YW, Lu CC, Lo MH, Hsieh KS, Li SC, Chang WC, Kuo HC*. CYP2E1 Gene Polymorphisms Related to the Formation of Coronary Artery Lesions in Kawasaki Disease. Pediatr Infect Dis J. 2017 Nov;36(11):1039-1043. (2016, SCI IF: 2.486, ranking: 99/151, Q3 in IMMUNOLOGY)
Liang-Jen Wang, Ho-Chang Kuo*. Cognitive Development After Kawasaki Disease- Clinical Study and Validation Using a Nationwide Population-Based Cohort. Circ J. 2017 Sep 9. doi: 10.1253/circj.CJ-17-0557. (2016, SCI IF: 3.544, ranking: 44/126, Q2 in CARDIAC & CARDIOVASCULAR SYSTEMS)。
Kuo HC, Wong HS, Chang WP, Chen BK, Wu MS, Yang KD, Hsieh KS, Hsu YW, Liu SF, Liu X, Chang WC. Prediction for Intravenous Immunoglobulin Resistance by Using Weighted Genetic Risk Score Identified From Genome-Wide Association Study in Kawasaki Disease. Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001625. (SCI IF: 4.7) (2016, SCI IF: 4.743, ranking: 29/126, Q1 in CARDIAC & CARDIOVASCULAR SYSTEMS)。
Kuo HC, Li SC, Huang LH, Huang YH. Epigenetic hypomethylation and upregulation of matrix metalloproteinase 9 in Kawasaki disease. Oncotarget. 2017 Jul 28;8(37):60875-60891. (2016, SCI IF: 5.168, ranking: 48/190, Q2 in CELL BIOLOGY)
Kuo HC, Huang YH, Chung FH, Chen PC, Sung TC, Chen YW, Hsieh KS, Chen CS, Syu GD. Antibody Profiling of Kawasaki Disease Using Escherichia coli Proteome Microarrays. Mol Cell Proteomics. 2018 Mar;17(3):472-481. (SCI IF: 6.5) (2016, SCI IF: 6.54, ranking: 5/78, Q1 in BIOCHEMICAL RESEARCH METHODS)
Huang YH, Kuo HC, Li SC, Cai XY, Liu SF, Kuo HC*. HAMP promoter hypomethylation and increased hepcidin levels as biomarkers for Kawasaki disease. J Mol Cell Cardiol. 2018 Mar 2;117:82-87. (SCI IF: 5.6) (corresponding author)
Huang YH, Lo MH, Cai XY, Kuo HC*. Epigenetic hypomethylation and upregulation of NLRC4 and NLRP12 in Kawasaki disease. Oncotarget. 2018 Apr 10;9(27):18939-18948. (2016, SCI IF: 5.168, ranking: 48/190, Q2 in CELL BIOLOGY) (corresponding author)
Kuo HC, Lo CC, Lin PX, Kao CC, Huang YH, Lin BS. Wireless optical monitoring system identifies limb induration characteristics in patients with Kawasaki disease. J Allergy Clin Immunol. 2018 May 4. pii: S0091-6749(18)30631-6. (SCI IF: 13.258)
Kuo HC*, Guo MM, Lo MH, Hsieh KS, Huang YH. Effectiveness of intravenous immunoglobulin alone and intravenous immunoglobulin combined with high-dose aspirin in the acute stage of Kawasaki disease: study protocol for a randomized controlled trial. BMC Pediatr. 2018 Jun 22;18(1):200. doi: 10.1186/s12887-018-1180-1.