Expertise at Chang Gung System

Shih, Shin-Ru ,Ph.D.
Institution:
  • Research Center for Emerging Viral Infections, Chang Gung University
  • Department of Medical Biotechnology and Laboratory Science & Graduate Program of Biomedical Sciences, Chang Gung University
  • Clinical Virology Laboratory, Department of Clinical Pathology, Chang Gung Memorial Hospital
Position:
  • Director/Professor, Research Center for Emerging Viral Infections, Chang Gung University
  • Faculty in the Department of Medical Biotechnology and Laboratory Science & Graduate Program of Biomedical Sciences, Chang Gung University
  • Medical Director, Clinical Virology Laboratory, Department of Clinical Pathology, Chang Gung Memorial Hospital
Department:
  • Research Center for Emerging Viral Infections, Chang Gung University
  • Department of Medical Biotechnology and Laboratory Science & Graduate Program of Biomedical Sciences, Chang Gung University
  • Clinical Virology Laboratory, Department of Clinical Pathology, Chang Gung Memorial Hospital
Address: Research Center for Emerging Viral Infections, No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33302, Taiwan , R.O.C.
Tel: 886-3-2118800 ext. 5497 Fax: 886-3-2118174
E-mail: srshih@mail.cgu.edu.tw

Focus of Interest:
  • Biochemistry and Molecular Biology - Medicine
  • Infectious Diseases
  • Medical Technology, and Clinical Pathology
  • Microbiology

Fulltime Employment:
  • Director/Professor, Research Center for Emerging Viral Infections, Chang Gung University
  • Faculty in the Department of Medical Biotechnology and Laboratory Science & Graduate Program of Biomedical Sciences, Chang Gung University

Education:
  • 1991-1995 Ph.D. Graduate Program in Molecular Biology and Biochemistry, Rutgers University, the State University of New Jersey New Brunswick, New Jersey, U.S.A.
  • 1989-1991 M.S. Department of Biochemistry, National Taiwan University Taipei, Taiwan, R.O.C.
  • 1984-1988 B.S. Department of Medical Technology National Taiwan University

Honors and Awards:
  1. The Best Poster Presentation Award. The 3rd Chinese Laboratory Medicine Conference, Hong Kong. 1997.
  2. Outstanding Research Award. Chang Gung Universi
    3. ty, Taiwan. 2002.
  3. The National Medal for Outstanding Young People, (93年中華民國青年獎章), Taiwan, 2004.
  4. Outstanding Teaching Award. Chang Gung University, Taiwan. 2011.
  5. Most Valuable Article Award, Journal of Formosan Medical Association, (臺灣醫學會雜誌年度最有價值論文獎) Taiwan, 2011.
  6. 國科會特殊優秀人才獎勵 (2010-2014)；教育部優良教授獎勵(2011-2104).
  7. Outstanding Research Award. Chang Gung University, Taiwan. 2012.
  8. Distinguished Research Award. National Science Council (Ministry of Science and Technology), (101國科會傑出研究獎) Taiwan. 2013.

Selected Main Publications:
  1. Huang PN, Lin JY, Locker N, Kung YA, Hung CT, Lin JY, Huang HI, Li ML and *Shih SR. Far upstream element binding protein 1 binds the internal ribosomal entry site of enterovirus 71 and enhances viral translation and viral growth. Nucleic Acids Research, 2011, 39(2), 9633-9648.
  2. Huang CH, Chen CJ, Yen CT, Yu CP, Huang PN, Kuo RL, Lin SJ, Chang CK and *Shih SR. Caspase-1 deficient mice is more susceptible to influenza A virus infection with PA variation. Journal of Infectious Diseases. 2013: Aug. 28; PMID: 23901080.
  3. Liu YC, Kuo RL, Lin JY, Huang PN, Huang Y, Liu H, Arnold, JJ, Chen SJ, Wang, RY, Cameron CE and *Shih SR. Cytoplasmic viral RNA-dependent RNA polymerase disrupts the intracellular splicing machinery by entering nucleus and interfering with Prp8. PLoS Pathogens, 2014; 10(6):e1004199
  4. Huang PN and *Shih SR. Update on enterovirus 71 infection. Current Opinion in Virology, 2014; 98-104. doi: 10.1016/j.coviro.2014.03.007.
  5. Weng KF, Hung CT, Hsieh PT, Li ML, Chen GW, Kung YA, Huang PN, Kuo RL, Chen LL, Lin JY, Wang RYL, Chen SJ, Tang P, Horng JT, Huang HI, Wang JR, Ojcius DM, Brewer G and *Shih SR. A Cytoplasmic RNA Virus Generates Functional Viral Small RNAs and Self-Regulates Viral IRES Activity in Mammalian Cells. Nucleic Acids Research, 2014 Oct 28. pii: gku952. [Epub ahead of print] PMID:25352551

All Publications List

Board Certification:
  • Medical Technologist Licensure Taiwan