Expertise at Chang Gung System

Lai, Hsin-Chih ,Ph.D.
Institution: Chang Gung University
Position: Professor and Director
Department: Graduate Institute of Medical Biotechnology and Laboratory Sciences
Address: No. 259, Wen-Hwa 1st Road, Kwei-Shan Tao-Yuan, 333 Taiwan (R.O.C)
Tel: +886-3-2118800#3585 Fax: +886-3-2118800

Focus of Interest:
  • Biochemistry and Molecular Biology – Medicine
  • Immunology
  • Microbiology

Fulltime Employment:
  • Lecturer, National Taiwan University, 1994
  • Associate Professor, National Taiwan University, 1994–2006
  • Professor, National Taiwan University, 2006–2007
  • Professor, Chang Gung University, 2007-
  • Director, Department of Medical Biotechnology and Laboratory Science, 2009-
  • Principle Investigator, Institute for Biotechnology and Medicine Industry, Taiwan, 2009-
  • Advisory Committee, Center for Disease Control, Research and Diagnostic Center, 2013-
  • Joining the Editorial Board of PLOS ONE, 2014~
  • Special lecturer, Department of Molecular Medicine, University of Nottingham, UK (2002-2005)
  • Visiting Professor to University Cambridge, UK (1999)
  • Visiting Professor to University Nottingham, UK (2001-2005)
  • Editorial Board, Journal of Microbiological Methods. (2007- )
  • Chief Secretary, Taiwan Society of Microbiology (2003- )
  • Associate Editor-in-Chief, Journal of laboratory and biomedical sciences (2009-)
  • Executive editor, Journal of Microbiology, Infection and Immunity (2009-)

  • B.S., National Taiwan University, 1986
  • M.S., National Yang-Ming University, 1988
  • D.Phil., University of Cambridge, UK, 1994

Honors and Awards:
  • Oversea Research Scholarship (ORS) from the University of Cambridge, UK (1990-1993)
  • Ching-Sing Medical Researcher Award from the National Taiwan University (2006)

Selected Main Publications:
  1. Hsin-Chih Lai, Chih-Jung Chang, Chun-Hung Yang, Ya-Jing Hsu, Chang-Chieh Chen,Chuan-Sheng Lin, Yu-Huan Tsai, Tsung-Teng Huang,, David M. Ojcius, Ying-Huang Tsai and Chia-Chen Lu*. Activation of NK cell cytotoxicity by the natural compound 2,3-butanediol. Journal of Leukocyte Biology. 2012 Oct;92(4):807-14.
  2. Tsung-Teng Huang, Kowit-Yu Chong, David M. Ojcius1,, Yi-Hui Wu, Yun-Fei Ko, Cheng-Yeu Wu, Jan Martel1,, Chia-Chen Lu, Hsin-Chih Lai *& John D. Young*. Hirsutella sinensis mycelium suppresses interleukin-1b and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes. SCIENTIFIC REPORTS. 2013;3:1374.
  3. Chih-Jung Chang, Yi-Yuan Margaret Chen, Chia-Chen Lu, Chuan-Sheng Lin, Jan Martel, Sheng-Hui Tsai, Yun-Fei Ko, Tsung-Teng Huang, David M. Ojcius, Hsin-Chih Lai* & John D. Young*. Ganoderma lucidum Stimulates NK Cell Cytotoxicity by Inducing NKG2D/NCR Activation and Secretion of Perforin and Granulysin. Innate Immunity. 2014;20(3):301-11. Epub 2013 Jun 26.
  4. Huang TT, Wu SP, Chong KY, Ojcius DM, Ko YF, Wu YH, Wu CY, Lu CC, Martel J, Young JD*, Hsin-Chih Lai*. The medicinal fungus Antrodia cinnamomea suppresses inflammation by inhibiting the NLRP3 inflammasome. J Ethnopharmacol. 2014 Aug 8;155(1):154-64.
  5. Chia-Chen Lu, Ting-Shu Wu, Ya-Jing Hsu, Chih-Jung Chang, Chuan-Sheng Lin, Ju-Hsin Chia,  Tsu-Lan Wu,  Tsung-Teng Huang, Jan Martel, David M. Ojcius, John D. Young*, and Hsin-Chih Lai*. NK cells kill mycobacteria directly by releasing perforin and granulysin. J Leukoc Biol.2014 Dec;96(6):1119-29.

All Publications List