Lai, Hsin-Chih ,Ph.D.
Institution: Chang Gung University
Position: Professor and Director
Department: Graduate Institute of Medical Biotechnology and Laboratory Sciences
Address: No. 259, Wen-Hwa 1st Road, Kwei-Shan Tao-Yuan, 333 Taiwan (R.O.C)
Tel: +886-3-2118800#3585 Fax: +886-3-2118800
E-mail: hclai@mail.cgu.edu.tw
Focus of Interest:
Fulltime Employment:
Education:
Honors and Awards:
Selected Main Publications:
Institution: Chang Gung University
Position: Professor and Director
Department: Graduate Institute of Medical Biotechnology and Laboratory Sciences
Address: No. 259, Wen-Hwa 1st Road, Kwei-Shan Tao-Yuan, 333 Taiwan (R.O.C)
Tel: +886-3-2118800#3585 Fax: +886-3-2118800
E-mail: hclai@mail.cgu.edu.tw
Focus of Interest:
- Biochemistry and Molecular Biology – Medicine
- Immunology
- Microbiology
Fulltime Employment:
- Lecturer, National Taiwan University, 1994
- Associate Professor, National Taiwan University, 1994–2006
- Professor, National Taiwan University, 2006–2007
- Professor, Chang Gung University, 2007-
- Director, Department of Medical Biotechnology and Laboratory Science, 2009-
- Principle Investigator, Institute for Biotechnology and Medicine Industry, Taiwan, 2009-
- Advisory Committee, Center for Disease Control, Research and Diagnostic Center, 2013-
- Joining the Editorial Board of PLOS ONE, 2014~
- Special lecturer, Department of Molecular Medicine, University of Nottingham, UK (2002-2005)
- Visiting Professor to University Cambridge, UK (1999)
- Visiting Professor to University Nottingham, UK (2001-2005)
- Editorial Board, Journal of Microbiological Methods. (2007- )
- Chief Secretary, Taiwan Society of Microbiology (2003- )
- Associate Editor-in-Chief, Journal of laboratory and biomedical sciences (2009-)
- Executive editor, Journal of Microbiology, Infection and Immunity (2009-)
Education:
- B.S., National Taiwan University, 1986
- M.S., National Yang-Ming University, 1988
- D.Phil., University of Cambridge, UK, 1994
Honors and Awards:
- Oversea Research Scholarship (ORS) from the University of Cambridge, UK (1990-1993)
- Ching-Sing Medical Researcher Award from the National Taiwan University (2006)
Selected Main Publications:
- Hsin-Chih Lai, Chih-Jung Chang, Chun-Hung Yang, Ya-Jing Hsu, Chang-Chieh Chen,Chuan-Sheng Lin, Yu-Huan Tsai, Tsung-Teng Huang,, David M. Ojcius, Ying-Huang Tsai and Chia-Chen Lu*. Activation of NK cell cytotoxicity by the natural compound 2,3-butanediol. Journal of Leukocyte Biology. 2012 Oct;92(4):807-14.
- Tsung-Teng Huang, Kowit-Yu Chong, David M. Ojcius1,, Yi-Hui Wu, Yun-Fei Ko, Cheng-Yeu Wu, Jan Martel1,, Chia-Chen Lu, Hsin-Chih Lai *& John D. Young*. Hirsutella sinensis mycelium suppresses interleukin-1b and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes. SCIENTIFIC REPORTS. 2013;3:1374.
- Chih-Jung Chang, Yi-Yuan Margaret Chen, Chia-Chen Lu, Chuan-Sheng Lin, Jan Martel, Sheng-Hui Tsai, Yun-Fei Ko, Tsung-Teng Huang, David M. Ojcius, Hsin-Chih Lai* & John D. Young*. Ganoderma lucidum Stimulates NK Cell Cytotoxicity by Inducing NKG2D/NCR Activation and Secretion of Perforin and Granulysin. Innate Immunity. 2014;20(3):301-11. Epub 2013 Jun 26.
- Huang TT, Wu SP, Chong KY, Ojcius DM, Ko YF, Wu YH, Wu CY, Lu CC, Martel J, Young JD*, Hsin-Chih Lai*. The medicinal fungus Antrodia cinnamomea suppresses inflammation by inhibiting the NLRP3 inflammasome. J Ethnopharmacol. 2014 Aug 8;155(1):154-64.
- Chia-Chen Lu, Ting-Shu Wu, Ya-Jing Hsu, Chih-Jung Chang, Chuan-Sheng Lin, Ju-Hsin Chia, Tsu-Lan Wu, Tsung-Teng Huang, Jan Martel, David M. Ojcius, John D. Young*, and Hsin-Chih Lai*. NK cells kill mycobacteria directly by releasing perforin and granulysin. J Leukoc Biol.2014 Dec;96(6):1119-29.