Expertise at Chang Gung System

Lin, Hsi-Hsien ,Ph.D.
Institution: Chang Gung University
Position: Professor
Department: Department of Microbiology and Immunology
Address: No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33302, Taiwan (R.O.C.)
Tel: [886]-(0)3-2118800-ext3321 Fax: [886]-(0)3-2118469 +886-3-3285056
E-mail: hhlin@mail.cgu.edu.tw

Focus of Interest:
  • Immunology

Fulltime Employment:
  • 2011/8–present Professor/Laboratory Head, Laboratory of Molecular Immunology, Department of Microbiology and Immunology, Chang Gung University, Taiwan.
  • 2007/8–2011/7 Associate Professor/Laboratory Head, Laboratory of Molecular Immunology, Department of Microbiology and Immunology, Chang Gung University, Taiwan.
  • 2004/12–2007/7 Assistant Professor/Laboratory Head, Laboratory of Molecular Immunology, Department of Microbiology and Immunology, Chang Gung University, Taiwan.
  • 2000/7–2004/11 Group leader/Senior Research Fellow, Sir William Dunn School of Pathology, the University of Oxford, UK.

Education:
  • 1992/8 – 1997/12 Ph.D., Oak Ridge Graduate School of Biomedical Sciences, University of Tennessee – Knoxville, TN, U.S.A.

Selected Main Publications:
  1. N.-Y. Chiang, C.-C. Hsiao, Y.-S. Huang, H.-Y. Chen, I-J. Hsieh, G.-W. Chang, H.-H. Lin* 2011 Disease-associated GPR56 mutations cause bilateral frontoparietal polymicrogyria via multiple mechanisms.J. Biol. Chem. 286(16): 14215-14225.
  2.  Y.-M. Peng, Martijn D.B. van de Garde, K.-F. Cheng, P.A. Baars, R.A.W. van Lier, C.R. Mackay, H.-H. Lin*, and J. Hamann* 2011 Specific expression of GPR56 by human cytotoxic lymphocytes. J. Leukoc. Biol. 90:735-740
  3. Y.-S. Huang, N.-Y. Chiang, C.-H. Hu, C.-C. Hsiao, K.-F. Cheng, W.-P. Tsai, Simon Yona, Martin Stacey, Siamon Gordon, G.-W. Chang* and H.-H. Lin* 2012 Activation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomains. Mol. Cell. Biol. 32(8): 1408-1420
  4. W.-Y. Tseng, Y.-S. Huang, N.-Y. Chiang, Y.-P. Chou, Y.-J. Jan Wu, S.-F. Luo, C.-F. Kuo, K.-M. Lin, andH.-H. Lin* 2013 Increased soluble CD4 in serum of rheumatoid arthritis patients is generated by matrix metalloproteinase (MMP)-like proteinases. PLoS ONE  8(5): e63963. 
  5. C.-C. Hsiao&, W.-C. Wang&, W.-L. Kuo, H.-Y. Chen, T.-C. Chen, J. Hamann, H.-H. Lin* 2014 CD97 inhibits cell migration in human fibrosarcoma cells by modulating TIMP-2/MT1-MMP/MMP-2 activity. FEBS Journal 281(21):4878-91.

All Publications List