Expertise at Chang Gung System

Chien, Kun-Yi ,Ph.D.
Institution: Chang Gung University
Position: Associate professor
Department: Department of Biochemistry and Molecular Biology
Address: 259 Wen-Hwa 1st Road, Kwei-Shan, Tao-Yuan,Taiwan,333, R.O.C.
Tel: +886-3-3218800 Fax: +886-3-3218700
E-mail: kychien@mail.cgu.edu.tw

Focus of Interest:
  • Biochemistry and Molecular Biology - Medicine

Fulltime Employment:
  • 1997/01 ~ 1997/06 Postdoctoral Fellow, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, R. O. C.
  • 1997/11 ~ 2001/12 Postdoctoral Fellow, Department of Life Sciences,National Tsing Hua University, Hsinchu, Taiwan, R. O. C.
  • 2002/3-2003/10 Assistant Research Professor, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R. O. C.
  • 2003/10-2013/07 Assistant Professor, Chang Gung University, Taoyuan, Taiwan, R. O. C.

Education:
  • 1983 ~ 1987 B.S. Department of Microbiology, Soochow University Taipei, Taiwan, R. O. C.
  • 1987 ~ 1989 M.S. Institute of Life Sciences, National Tsing Hua University Hsinchu, Taiwan, R. O. C.
  • 1989 ~ 1993 Ph.D. Institute of Life Sciences, National Tsing Hua University Hsinchu, Taiwan, R. O. C.

Selected Main Publications:
  1. Gopinath RK, You ST, Chien KY, Swamy KB, Yu JS, Schuyler SC, Leu JY. The Hsp90-dependent proteome is conserved and enriched for hub proteins with high levels of protein-protein connectivity. Genome Biol Evol. 2014 Oct 13; 6(10):2851-65.
  2. Dong YM, Chien KY, Chen JT, Lin SJ, Wang TC, Yu JS. Site-specific separation and detection of phosphopeptide isomers with pH-mediated stacking capillary electrophoresis-electrospray ionization-tandem mass spectrometry. J Sep Sci. 2013 May;36(9-10):1582-9.
  3. Lin SY, Li TY, Liu Q, Zhang C, Li X, Chen Y, Zhang SM, Lian G, Liu Q, Ruan K, Wang Z, Zhang CS, Chien KY, Wu J, Li Q, Han J, Lin SC. GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. Science. 2012 Apr 27;336(6080):477-81.
  4. Feng Y, Chien KY, Chen HL, Chiu CH. Pseudogene recoding revealed from proteomic analysis of salmonella serovars. J Proteome Res. 2012 Mar 2; 11(3):1715-9.
  5. Chi LM, Lee CW, Chang KP, Hao SP, Lee HM, Liang Y, Hsueh C, Yu CJ, Lee IN, Chang YJ, Lee SY, Yeh YM, Chang YS, Chien KY*, Yu JS*. Enhanced interferon signaling pathway in oral cancer revealed by quantitative proteome analysis of microdissected specimens using 16O/18O labeling and integrated two-dimensional LC-ESI-MALDI tandem MS. Mol Cell Proteomics. 2009 Jul;8(7):1453-74.

All Publications List

Board Certification:
  • Taiwan Proteomics Society