Page 51 - 林口長庚醫研部電子報-2019年6月刊
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Incidence per 1,000                                            a
                                                   person-years (95% CI)               Adjusted HR (95% CI)

          Hyperthyroidism

          Nonpsoriatic controls                        0.75 (0.71‒0.81)                    1.00 (referent)


          Psoriasis group                              0.91 (0.86‒0.97)                  1.22 (1.11‒1.33)***

          Psoriatic arthritis group                    0.96 (0.77‒1.18)                   1.32 (1.07‒1.65)*


          Graves' disease

          Nonpsoriatic controls                        0.51 (0.47‒0.55)                    1.00 (referent)

          Psoriasis group                              0.64 (0.59‒0.69)                  1.26 (1.13‒1.41)***


          Psoriatic arthritis group                    0.68 (0.52‒0.87)                   1.38 (1.07‒1.79)*

          Hypothyroidism

          Nonpsoriatic controls                        0.42 (0.38‒0.46)                    1.00 (referent)


          Psoriasis group                              0.59 (0.55‒0.64)                  1.38 (1.23‒1.56)***

          Psoriatic arthritis group                    0.67 (0.51‒0.86)                  1.74 (1.34‒2.27)***


          Thyroiditis

          Nonpsoriatic controls                        0.27 (0.24‒0.30)                    1.00 (referent)


          Psoriasis group                              0.38 (0.34‒0.42)                  1.42 (1.22‒1.64)***

          Psoriatic arthritis group                    0.52 (0.39‒0.69)                  2.05 (1.51‒2.77)***

          Hashimoto's thyroiditis


          Nonpsoriatic controls                        0.12 (0.10‒0.15)                    1.00 (referent)

          Psoriasis group                              0.18 (0.16‒0.21)                  1.47 (1.18‒1.82)**


          Psoriatic arthritis group                    0.24 (0.16‒0.37)                  2.09 (1.34‒3.24)**




             Incident thyroid diseases in people with psoriatic disease



          CI, confidence interval; HR, hazard ratio; *, P < 0.05; **, P

                                    < 0.01; ***, P < 0.0001.

          aCompared with non-psoriasis controls after adjusted for age,
          gender, and comorbidities including type 2 diabetes mellitus,

                                    hypertension, and hyperlipidemia.





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