Page 51 - 林口長庚醫研部電子報-2019年6月刊
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Incidence per 1,000 a
person-years (95% CI) Adjusted HR (95% CI)
Hyperthyroidism
Nonpsoriatic controls 0.75 (0.71‒0.81) 1.00 (referent)
Psoriasis group 0.91 (0.86‒0.97) 1.22 (1.11‒1.33)***
Psoriatic arthritis group 0.96 (0.77‒1.18) 1.32 (1.07‒1.65)*
Graves' disease
Nonpsoriatic controls 0.51 (0.47‒0.55) 1.00 (referent)
Psoriasis group 0.64 (0.59‒0.69) 1.26 (1.13‒1.41)***
Psoriatic arthritis group 0.68 (0.52‒0.87) 1.38 (1.07‒1.79)*
Hypothyroidism
Nonpsoriatic controls 0.42 (0.38‒0.46) 1.00 (referent)
Psoriasis group 0.59 (0.55‒0.64) 1.38 (1.23‒1.56)***
Psoriatic arthritis group 0.67 (0.51‒0.86) 1.74 (1.34‒2.27)***
Thyroiditis
Nonpsoriatic controls 0.27 (0.24‒0.30) 1.00 (referent)
Psoriasis group 0.38 (0.34‒0.42) 1.42 (1.22‒1.64)***
Psoriatic arthritis group 0.52 (0.39‒0.69) 2.05 (1.51‒2.77)***
Hashimoto's thyroiditis
Nonpsoriatic controls 0.12 (0.10‒0.15) 1.00 (referent)
Psoriasis group 0.18 (0.16‒0.21) 1.47 (1.18‒1.82)**
Psoriatic arthritis group 0.24 (0.16‒0.37) 2.09 (1.34‒3.24)**
Incident thyroid diseases in people with psoriatic disease
CI, confidence interval; HR, hazard ratio; *, P < 0.05; **, P
< 0.01; ***, P < 0.0001.
aCompared with non-psoriasis controls after adjusted for age,
gender, and comorbidities including type 2 diabetes mellitus,
hypertension, and hyperlipidemia.
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