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   顯微鏡核心實驗室

　

　

 Electronic Microscope

　

　

　

　

　

　                              研 究 成 果 　

電子顯微鏡

  • 2021
  1. Li-Ching Chang, Chiu-Yen Chung, Chun-Hui Chiu, Martin Hsiu-Chu Lin, and Jen-Tsung Yang.The Effect of Polybutylcyanoacrylate Nanoparticles as a Protos DeliveryVehicle on Dental Bone Formation. Int. J. Mol. Sci. 2021, 22, 4873.
  2. Martin Hsiu-Chu Lin,Ping-Shan Lai,Li-Ching Chang,Wei-Chao Huang, Ming-Hsueh Lee,Kuo-Tai Chen,Chiu-Yen Chung and Jen-Tsung Yang. Characterization and Optimization of Chitosan-Coated Polybutylcyanoacrylate Nanoparticles for the Transfection-Guided Neural Differentiation of Mouse Induced Pluripotent Stem Cells. Int. J. Mol. Sci. 2021, 22, 8741.
  3. Chiun‑Wei Huang, Chia‑Pao Chuang, Yan‑Jun Chen, Hsu‑Yuan Wang, Jia‑Jia Lin1 Chiung‑Yin Huang, Kuo‑Chen Wei and Feng‑Ting Huang. Integrin α2β1‑targeting ferritin nanocarrier traverses the blood–brain barrier for effective glioma chemotherapy. Huang et al. J Nanobiotechnol (2021) 19:180
  4. Chung-An Chen, Yu-Jui Huang, Natalie Yi-Ju Ho, Tse-Hao Huang, Tsung-Ting Tsai. Smartphone-assisted fluorescent analysis of polyT-Cu-nanoprobes using nucleic acid amplification test for the diagnosis of tuberculosis. Analytical Biochemistry 630 (2021) 114340
  5. Thi Tuong Van Tran, Selvaraj Rajesh Kumar , Chi Hieu Nguyen, Jing Wen Lee, Hui-An Tsai, Chia-Hsun Hsieh, Shingjiang Jessie Lu. High-permeability graphene oxide and poly(vinyl pyrrolidone) blended poly(vinylidene fluoride) membranes: Roles of additives and their cumulative effects. Journal of Membrane Science 619 (2021) 118773
  6. Yu-Tzu Huang, Selvaraj Rajesh Kumar, Hao-Chun Chan, Zih-Huei Jhan, Dave W. Chen,Shingjiang Jessie Lue. Efficacy of antimicrobial peptides (AMPs) against Escherichia coli and bacteria morphology change after AMP exposure. Journal of the Taiwan Institute of Chemical Engineers 126 (2021) 307-312
  7. G.R. Nirmal, Zih-Chan Lin, Ming-Jun Tsai, Shih-Chun Yang, Ahmed Alalaiwe, Jia-You Fang. Photothermal treatment by PLGA–gold nanorod–isatin nanocomplexes under near-infrared irradiation for alleviating psoriasiform hyperproliferation. Journal of Controlled Release 333 (2021) 487–499
  8. Periyasamy Sundaresan, Chun-Chieh Fu, Shou-Hsuan Liu, Ruey-Shin Juang. Facile synthesis of chitosan-carbon nanofiber composite supported copper nanoparticles for electrochemical sensing of carbendazim. Colloids and Surfaces A: Physicochemical and Engineering Aspects 625 (2021) 126934
  9. Mai Lien Tran a, Chun-Chieh Fu b, Lin-Yu Chiang b, Chien-Te Hsieh c, Shou-Hsuan Liu d, Ruey-Shin Juang. Immobilization of TiO2 and TiO2-GO hybrids onto the surface of acrylic acid-grafted polymeric membranes for pollutant removal: Analysis of photocatalytic activity. Journal of Environmental Chemical Engineering 8 (2020) 104422 Available
  10. Chi Hieu Nguyen, Mai Lien Tran, Thi Tuong Van Tran, Ruey-Shin Juang. Efficient removal of antibiotic oxytetracycline from water by Fenton-like reactions using reduced graphene oxide-supported bimetallic Pd/nZVI nanocomposites. Journal of the Taiwan Institute of Chemical Engineers 119 (2021) 80-89
  11. Periyasamy Sundaresan, Chun-Chieh Fu, Chien-Te Hsieh, Shou-Hsuan Liu, Ruey-Shin Juang. Simultaneous and sensitive determination of uric acid and p-cresol in human urine samples based on activated graphite-supported gadolinium hydroxide. Journal of the Taiwan Institute of Chemical Engineers 127 (2021) 7-16
  12. Periyasamy Sundaresan, Cheng-Han Lee, Chun-Chieh Fu, Shou-Hsuan Liu, Ruey-Shin Juang. Ultrasound-assisted synthesis of barium tungstate encapsulated carbon anofiber composite for real-time sensing of p-cresol in human urine samples. Microchemical Journal 166 (2021) 106239
  13. Chi Hieu Nguyen, Chun-Chieh Fu, Ze-Han Chen, Thi Tuong Van Tran, Shou-Hsuan Liu,Ruey-Shin Juang. Enhanced and selective adsorption of urea and creatinine on amine-functionalized mesoporous silica SBA-15 via hydrogen bonding. Microporous and Mesoporous Materials 311 (2021) 110733
  14. Sheng-Chuan Wang, Shou-Hsuan Liu, Chun-Chieh Fu, Yu-Sheng Hsiao, Ruey- Shin Juang. Design and fabrication of electrospun mixed-matrix multi-layered membranes containing tri-n-octylphosphine oxide for efficient adsorption of p-cresol. Colloids and Surfaces A: Physicochemical and Engineering Aspects 627 (2021) 127192
  • 2020
  1. Chi Hieu Nguyen, Chun-Chieh Fu, Deng-Yi Kao, Thi Tuong Van Tran, Ruey-Shin Juang. Adsorption removal of tetracycline from water using poly(vinylidene fluoride)/polyaniline-montmorillonite mixed matrix membranes. Journal of the Taiwan Institute of Chemical Engineers 112 (2020) 259-270
  2. Ying-Pei Hsu, Hung-Wei Yang, , Nan-Si Li, Ying-Tzu Chen, Hao-Han Pang, and See-Tong Pang. Instrument-Free Detection of FXYD3 Using Vial-Based Immunosensor for Earlier and Faster Urothelial Carcinoma Diagnosis. ACS Sens. 2020, 5, 928−935
  3. Ying-Pei Hsu, Nan-Si Li, Ying-Tzu Chen, Hao-Han Pang, Kuo-Chen Wei, Hung-Wei Yang. A serological point-of-care test for Zika virus detection and infection surveillance using an enzyme-free vial immunosensor with a smartphone. Biosensors and Bioelectronics 151 (2020) 111960
  4. Wen-Lin Hsu, Chiung-Yin Huang, Ying-Pei Hsu, Tsong-Long Hwang, Shih-Hsin Chang. Hay-Yan J. Wang, Li-Ying Feng, Shiow-Jyu Tzou, Kuo-Chen Wei, Hung-Wei Yang. On-skin glucose-biosensing and on-demand insulin-zinc hexamers delivery using microneedles for syringe-free diabetes management. Chemical Engineering Journal 398 (2020) 125536
  5. Wen-Lin Hsu, Chiung-Yin Huang, Ying-Pei Hsu, Tsong-Long Hwang, Shih-Hsin Chang, Hay-Yan. Wang, Li-Ying Feng, Shiow-Jyu Tzou, Kuo-Chen Wei, Hung-Wei Yang. On-skin glucose-biosensing and on-demand insulin-zinc hexamers delivery using microneedles for syringe-free diabetes management, Chemical Engineering Journal, 398 (2020) 125536
  6. Nan-Si Li, Ying-Tzu Chen, Ying-Pei Hsu, Hao-Han Pang, Chiung-Yin Huang, Yow-Ling Shiue, Kuo-Chen Wei, Hung-Wei Yang. Mobile healthcare system based on the combination of a lateral flow pad and smartphone for rapid detection of uric acid in whole blood, Biosensors and Bioelectronics, 164 (2020) 112309
  7. Hao-Han Pang, Yong-Chen Ke, Nan-Si Li, Ying-Tzu Chen, Chiung-Yin Huang, Kuo- Chen Wei, Hung-Wei Yang . A new lateral flow plasmonic biosensor based on gold-viral biomineralized nanozyme for on-site intracellular glutathione detection to evaluate drug-resistance level, Biosensors and Bioelectronics, 165 (2020) 112325
  8. Hung-Ling Yu, Chun-Chieh Fu, Yu-Sheng Hsiao, Chu-Chun Chien, Ruey-Shin Juang. Preparation of porous phosphine oxide-incorporated polymer membranes for selective removal of p -cresol from simulated serum: A preliminary study, Journal of the Taiwan Institute of Chemical Engineers,107 (2020) 1–14
  9. Ruey-Shin Juang, Yu-Wei Cheng, Wan-Tzu Chen, Kuan-Syun Wang, Chun-Chieh Fu, Shou-Hsuan Liu, Ru-Jong Jeng, Cheng-Cheung Chen, Ming-Chien Yang, Ting-Yu Liu. Silver nanoparticles embedded on mesoporous-silica modified reduced graphene-oxide nanosheets for SERS detection of uremic toxins and parathyroid hormone, Applied Surface Science, 521 (2020) 146372
  10. Chun-Chieh Fu, Yu-Sheng Hsiao, Jia-Wen Ke, We-Lin Syu, Ting-Yu Liu, Shou-Hsuan Liu, Ruey-Shin Juang. Adsorptive removal of p-cresol and creatinine from simulated serum using porous polyethersulfone mixed-matrix membranes, Separation and Purification Technology, 245 (2020) 116884
  11. Nguyen Chi Hieu, Tran Mai Lien, Tran Thi Tuong Van, Ruey-Shin Juang. Enhanced removal of various dyes from aqueous solutions by UV and simulated solar photocatalysis over TiO2/ZnO/rGO composites, Separation and Purification Technology, 232 (2020) 115962
  12. Chi Hieu Nguyen, Hai Nguyen Tran, Chun-Chieh Fu,Ying-Tong Lu, Ruey-Shin Juang. Roles of adsorption and photocatalysis in removing organic pollutants from water by activated carbon supported titania composites:Kineticaspects, Journal of the Taiwan Institute of Chemical Engineers, 109(2020)51-61
  13. Chun-Chieh Fu, Hai Nguyen Tran, Xing-Han Chen, Ruey-Shin Juang. Preparation of polyaminated Fe3O4@chitosan core-shell magnetic nanoparticles for efficient adsorption of phosphate in aqueous solutions, Journal of Industrial and Engineering Chemistry, 83 (2020) 235–246
  14. Fang-I. Lai, Jui-Fu Yang, Yu-Chao Hsu, Shou-Yi Kuo. Omnidirectional light harvesting enhancement of dye-sensitized solar cells decorated with two-dimensional ZnO nanoflowers, Journal of Alloys and Compounds 815 (2020) 152287
  • 2019
  1. Hung-Wei Yang, Shin-Pon Ju, Hsing-Yin Chen, Yi-Chi Cheng,and Wen-Lin Hsu. Ovalbumin-Loaded Gelation Microneedles Made of Predictive Formulation by Molecular Dynamics Simulation for Enhancement of Skin Immunization, ACS Biomater. Sci. Eng. 2019, 5, 6012−6021
  2. Ching-Chi Chiu, Hung-Li Wang, Yi-Hsin Weng, Rou-Shayn Chen, Chiung-Mei Chen, Tu-Hsueh Yeh, Chin-Song Lu, Yu-Jie Chen, Yu-Chuan Liu, Ying-Zu Huang, Kuo-Hsuan Chang. Generation of induced pluripotent stem cells from a young-onset Parkinson's disease patient carrying the compound heterozygous PLA2G6 p.D331Y/p.M358IfsX mutations, Stem Cell Research, 40 (2019) 101552
  3. Ching-Chi Chiu & Chin-Song Lu & Yi-Hsin Weng & Ying-Ling Chen & Ying-Zu Huang & Rou-Shayn Chen & Yi-Chuan Cheng & Yin-Cheng Huang & Yu-Chuan Liu & Szu-Chia Lai & Kun-Jun Lin & Yan-Wei Lin & Yu-Jie Chen1 & Chao-Lang Chen & Tu-Hsueh Yeh & Hung-Li Wang. PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model. Molecular Neurobiology (2019) 56:3835–3853
  4. Ching-Chi Chiu, Tu-Hsueh Yeh, Rou-Shayn Chen, Hua-Chien Chen, Ying-Zu Huang, Yi-Hsin Weng, Yi-Chuan Cheng, Yu-Chuan Liu, Ann-Joy Cheng, Ya-Ching Lu, Yu-Jie Chen, Yan-Wei Lin, Chia-Chen Hsu, Ying-Ling Chen, Chin-Song Lu, and Hung-Li Wang, Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade, ORIGINAL RESEARCH published: 13 September 2019 doi: 10.3389/fncel.2019.00399
  5. Ru-Siou Hsu, Pei-Yueh Chen, Jen-Hung Fang, You-Yin Chen, Chien-Wen Chang, Yu-Jen Lu, and Shang-Hsiu Hu.Adaptable Microporous Hydrogels of Propagating. NGF-Gradient by Injectable Building Blocks for Accelerated Axonal Outgrowth. Adv. Sci. 2019, 6, 1900520(1 of 14)
  6. Tommy Nai-Jen Chang, Kuang-Te Chen, Tessa Gorden, Bassem W. Daniel, Catherine Hernon, Mark Shafarenko, Yen-Lin Huang, Johhny Chuieng-Yi Lu,and David Chwei-Chin Chuang. Vascularized Brachial Plexus Allotransplantation—An Experimental Study in Brown Norway and Lewis Rats. Transplantation 2019;103: 149–159.
  7. H.H. Pang, P.Y. Chen, K.C. Wei, C.W. Huang, Y.L. Shiue, C.Y. Huang, H.W. Yang. Convection-enhanced delivery of a virus-like nanotherapeutic agent with dual-modal imaging for besiegement and eradication of brain tumors. Theranostics 9, 1752-1763 (2019)
  8. C. Peng, M.Y. Hua, N.S. Li, Y.P. Hsu, Y.T. Chen, C.K. Chuang, S.T. Pang, H.W. Yang. A colorimetric immunosensor based on self-linkable dual-nanozyme for ultrasensitive bladder cancer diagnosis and prognosis monitoring. Biosensors and Bioelectronics 126, 581-589 (2019).
  9. Ming-Kai Hsieh, Elsie Khai-Woon Toh, Tsung-Ting Tsai, Chi-Chien Niu, Shinn-Chih Wu, Po-Ling Lai. Plasmid BMP-2–Embedded Gelatin Sponge As A Gene-Activated Matrix for Preosteoblast Differentiation. Journal of Drug Delivery Science and Technology 53(2019)101129.
  10. Martin Hsiu-Chu Lin, Chiu-Yen Chung, Kuo-Tai Chen, Jih-Chao Yeh, Tsong-Hai Lee, Ming-Hsueh Lee, I-Neng Lee, Wei-Chao Huang and Jen-Tsung Yang. Comparison between Polybutylcyanoacrylate Nanoparticles with Either Surface-Adsorbed or Encapsulated Brain-Derived Neurotrophic Factor on the Neural Differentiation of iPSCs. International Journal of Molecular Sciences 2019, 20, 182.
  11. Thi Tuong Van Tran, S. Rajesh Kumar, Shingjiang Jessie Lue. Separation mechanisms of binary dye mixtures using a PVDF ultrafiltration membrane: Donnan effect and intermolecular interaction. Journal of Membrane Science 575 (2019) 38–49.
  12. Chia-Chang Lin, Jian-Song Liao. Production of CuO nanoparticles using a simple precipitation method in a rotating packed bed with blade packings. Journal of Alloys and Compounds 775 (2019) 419-426.
  13. Ming-Kai Hsieh, Chia-Jung Wu, Xuan-Chun Su, Yi-Chen Chen, Tsung-Ting Tsai, Chi-Chien Niu, Po-Liang Lai, Shinn-Chih Wu. Bone regeneration in Ds-Red pig calvarial defect using allogenic transplantation of EGFP-pMSCs – a comparison of host cells and seeding cells in the scaffold Short title: In vivo comparison of host cells and seeding cells. PLOS ONE doi: 10.1371/journal.pone.0215499
  14. Kuan-Lin Ku, Yu-Shan Wu, Chi-Yun Wang, Ding-Wei Hong, Zong-Xing Chen, Ching-An Huang, I-Ming Chu and Po-Liang Lai. Incorporation of surfacemodified hydroxyapatite into poly(methyl methacrylate) to improve biological activity and bone ingrowth. royalsocietypublishing.org/journal/rsos R. Soc. open sci. 6: 182060
  • 2018
  1. Hung-Wei Yang , Shin-Pon Jub, Che-Hao Cheng , Ying-Tzu Chen , Yu-Sheng Lin , See-Tong Pang. Aptasensor designed via the stochastic tunneling-basin hopping method for biosensing of vascular endothelial growth factor. Biosensors and Bioelectronics Volume 119, 15 November 2018, Pages 25-33
  2. K.T. Shalumon, Chialin Sheu , Chih-Hao Chen , Shih-Heng Chen , Gils Jose , Chang-Yi Kuo , Jyh-Ping Chen. Multi-functional electrospun antibacterial core-shell nanofibrous membranes for prolonged prevention of post-surgical tendon adhesion and inflammation. Acta Biomaterialia 72 (2018) 121–136
  3. Chiu CC, Lu CS, Weng YH, Chen YL, Huang YZ, Chen RS, Cheng YC, Huang YC, Liu YC, Lai SC, Lin KJ, Lin YW, Chen YJ, Chen CL, Yeh TH, Wang HL. PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress,Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse ModelMolecular Neurobiology 2018 Aug 8. doi: 10.1007/s12035-018-1118-5
  4. Ching-Yun Hsu, PhD, Calvin T. Sung, BSc, Ibrahim A. Aljuffali, Phc, Chun-Han Chen, MD, Kai-Yin Hu, MSc, Jia-You Fang, PhD. Intravenous anti-MRSA phosphatiosomes mediate enhanced affinity to pulmonary surfactants for effective treatment of infectious pneumonia. Nanomedicine: Nanotechnology, Biology, and Medicine 14 (2018) 215–225
  5. Ahmed Alalaiwe, Pei-Wen Wang, Po-Liang Lu, Ya-Ping Chen, Jia-You Fang, Shih-Chun Yang. Synergistic Anti-MRSA Activity of Cationic Nanostructured Lipid Carriers in Combination With Oxacillin for Cutaneous Application. Front. Microbiol.2018 June.doi: 10.3389/fmicb.2018.01493.
  6. Shih-Chun Yang, Tse-Hung Huang, Chun-Hui Chiu, Wei-Ling Chou, Ahmed Alalaiwe, Yuan-Chieh Yeh, Kuan-Wen Su, Jia-You Fang. The atopic dermatitis-like lesion and the associated MRSA infection and barrier dysfunction can be alleviated by 2,4-dimethoxy-6-methylbenzene-1,3-diol from Antrodia camphorata. J. Dermatol. Sci. 2018 Sep. doi: 10.1016/j.jdermsci.
  7. Wei Xiong Siow, Yi-Ting Chang, Michal Babič, Yi-Ching Lu, Daniel Horák, Yunn-Hwa Ma. Interaction of poly-l-lysine coating and heparan sulfate proteoglycan on magnetic nanoparticle uptake by tumor cells. International Journal of Nanomedicine downloaded from https://www.dovepress.com/ by 179.61.191.60 on 21-Mar-2018
  8. Yen CF, Hsu CK, Lu CW. Topical betaxolol for treating relapsing paronychia with pyogenic granuloma-like lesions induced by epidermal growth factor receptor inhibitors. J Am Acad Dermatol. 2018 Jun;78(6):e143-e144. doi: 10.1016/j.jaad.2018.01.015. Epub 2018 Jan 12.
  9. Mei-Hui Lin, Chi-Chun Li, Jwu-Ching Shu, Hao-Wei Chu, Chao-Chin Liu, and Chih-Ching Wu. Exoproteome Profiling Reveals the Involvement of the Foldase PrsA in the Cell Surface Properties and Pathogenesis of Staphylococcus aureus. Proteomics, 18, 1700195(2018).
  10. Ruey-Shin Juang, Yao-Chung Yei, Chien-Shiun Liao, Kuen-Song Lin, Hsi-Chuan Lu, Sea-Fue Wang, An-Cheng Sun. Synthesis of magnetic Fe 3 O 4 /activated carbon nanocomposites with high surface area as recoverable adsorbents. Journal of the Taiwan Institute of Chemical Engineers 90 (2018) 51–60.
  11. Ruey-Shin Juang, Chu-Chun Chien, Chao-Ling Yao, Ssu-Han Yu, An-Cheng Sun. Preparation of magnetically recoverable mesoporous silica nanocomposites for effective adsorption of urea in simulated serum. Journal of the Taiwan Institute of Chemical Engineers 91 (2018) 22–31.
  • 2017
  1. Tarsis F. Gesteira, Mingxia Sun, Yvette M. Coulson-Thomas, Yu Yamaguchi, Lung-Kun Yeh, Vincent Hascall, and Vivien J. Coulson-Thomas Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation. Invest Ophthalmol Vis Sci. 2017;58:4407–4421.
  2. Chih-Hao Chen, Shih-Hsien Chen, Shih-Hsuan Mao, Ming-Jin Tsai, Pang-Yun Chou,Chien-Hung Liao, Jyh-Ping Chen. Injectable thermosensitive hydrogel containing hyaluronic acid andchitosan as a barrier for prevention of postoperative peritonealadhesion. Carbohydrate Polymers 173 (2017) 721–731
  3. Chung-Chuan Chou, MD;* Po-Cheng Chang, MD;* Yi-Chia Wei, MD; Kuang-Yung Lee, MD, PhD “Optical Mapping Approaches on Muscleblind-Like Compound Knockout Mice for Understanding Mechanistic Insights Into Ventricular Arrhythmias in Myotonic Dystrophy”, Journal of the American Heart Association. 2017;6:e005191. DOI: 10.1161/JAHA.116.005191. (IF2016=4.863)
  4. Feng-Wei Lin, Pin-Yuan Chen, Kuo-Chen Wei, Chiung-Yin Huang, Chih-Kuang Wang, Hung-Wei Yang , “Rapid In Situ MRI Traceable Gel-forming Dual-drugDelivery for Synergistic Therapy of Brain Tumor” Theranostics 2017; 7(9): 2524-2536. (IF2016=8.712)
  5. Jing-Fong Liao, Jin-Ching Lee, Chun-Kuang Lin, Kuo-Chen Wei, Pin-Yuan Chen, Hung-Wei Yang, “Self-Assembly DNA Polyplex Vaccine inside Dissolving Microneedles for High-Potency Intradermal Vaccination” Theranostics 2017; 7(10): 2593-2605. (IF2016=8.712)
  6. Chun-Wei Lu, Hong-Shang Hong, Chin-Fang Lu, Yu-Shien Ko “Human papillomavirus-70 infection as a possible pathogenesis of eruptive scrotal calcinosis” Dermatologica Sinica 2017, Vol. 35, Issue 3, 152-154. (IF2016=0.54)
  7. Chiu-Yen Chung, Martin Hsiu-Chu Lin, I-Neng Lee, Tsong-Hai Lee, Ming-Hsueh Lee and Jen-Tsung Yang “Brain-Derived Neurotrophic Factor Loaded PS80 PBCA Nanocarrier for In Vitro Neural Differentiation of Mouse Induced Pluripotent Stem Cells” International Journal of Molecular Sciences 2017, 18, 663; doi:10.3390 (IF2016=3.226)
  8. Lung-Hsuan Pan, See-Tong Pang, Po-Yu Fang, Cheng-Keng Chuang, Hung-Wei Yang, ”Label-Free Biochips for Accurate Detection of Prostate Cancer in the Clinic: Dual Biomarkers and Circulating Tumor Cells” Theranostics 2017, Vol. 7, Issue 17, 4289-4300. (IF2016=8.712)
  9. Tsung-Ting Tsai, Tse-Hao Huang, Chih-Jung Chang, Natalie Yi-Ju Ho, Yu-Ting Tseng & Chien-Fu Chen. Antibacterial cellulose paper made with silver-coated gold nanoparticles. Sci Rep, 2017 Apr 26;7:3155 (IF2016=4.259)
  • 2016
  1. Hsueh YJ, Huang SF, Lai JY, Chen HC* , Ma SC, Wu SE, Wang TK, Ma KS, Chen JK, Lai CH, Ma DHK*. Epithelial progenitors are preserved in collagenase-digested oral mucosa. Sci Rep, 2016 Nov 8;6:36266. (Impact Factor: 5.228)
  2. Hung-Wei Yang, Rung-Ywan Tsai, Jung-Po Chen, Shin-Pon Ju, Jing-Fong Liao, Kuo-Chen Wei, Wei-Lun Zou, and Mu-Yi Hua, “Fabrication of a Nanogold-Dot Array for Rapid and Sensitive Detection of Vascular Endothelial Growth Factor in Human Serum” ACS Appl. Mater. Interfaces 2016, 8, 30845−30852
  3. Charles Yuen Yung Loh, Aline Yen Ling Wang, Huang-Kai Kao, Esteban Cardona, Sheng-Hao Chuang, Fu-Chan Wei ”Episomal Induced Pluripotent Stem Cells Promote Functional Recovery of Transected Murine Peripheral Nerve” PLOS ONE |DOI:10.1371/journal.pone.0164696 October 13, 2016
  4. Lung-Hsuan Pan, Shin-Hung Kuo, Tzu-Yang Lin, Chih-Wen Lin, Po-Yu Fang, Hung-Wei Yang ,“ An electrochemical biosensor to simultaneously detect VEGF and PSA for early prostate cancer diagnosis based on graphene oxide/ssDNA/PLLA nanoparticles.＂Biosensors and Bioelectronics 2016 (IF=7.476)
  5. Kuo-Chen Wei, Feng-Wei Lin, Chiung-Yin Huang, Chen-Chi M Ma, Ju-Yu Chen, Li-Ying Feng, Hung-Wei Yang ,“1,3-Bis(2-chloroethyl)-1-nitrosourea-loaded bovine serum albumin nanoparticles with dual magnetic resonance–fluorescence imaging for tracking of chemotherapeutic agents” International Journal of Nanomedicine 2016:11 4065–4075 (IF=4.320)
  6. Shan-Shan Li, Chih-Wen Lin, Kuo-Chen Wei, Chiung-Yin Huang, Po-Hung Hsu, Hao-Li Liu, Yu-Jen Lu, Sheng-Chi Lin, Hung-Wei Yang & Chen-Chi M. Ma, “Non-invasive screening for early Alzheimer’s disease diagnosis by a sensitively immunomagnetic biosensor” Scientific Reports 6:25155 (2016) DOI: 10.1038/srep25155 (IF=5.228)
  7. Hsiao-Chien Chen, Fu-Der Mai, Kuang-Hsuan Yang, Hui-Yen Tsai,Chih-Ping Yang, Chien-Chung Chen, Chao-Hsuan Chen and Yu-Chuan Liu ,“An environmentally friendly etching agent: vapor from hot electron-activated liquid water”, Green Chem., 2016, 18, 3098-3105 (IF=8.506)
  8. Chia-Chang Lin , Yu-Shung Lin, Jui-Min Ho,” Adsorption of Reactive Red 2 from aqueous solutions using Fe3O4 nanoparticles prepared by co-precipitation in a rotating packed bed”, Journal of Alloys and Compounds 666 (2016) 153-158 (IF=3.014)
  • 2015
  1. Jui Fang, Yung-Liang Wan, Chin-Kuo Chen, and Po-Hsiang Tsui*, "Discrimination between newly formed and aged thrombi using empirical mode decomposition of ultrasound B-scan image," Journal of Biomedicine and Biotechnology (BioMed Research International), Vol. 2015, article ID 403293, 2015, 1 (SCI IF=3.169) (doi:10.1155/2015/403293)
  2. Jui Fang, Chin-Kuo Chen, Ju-Yi Peng, Chung-Hsin Hsu, Yung-Ming Jeng, Yu-Hsin Lee, Jen-Jen Lin, and Po-Hsiang Tsui*, “Changes in backscattered ultrasonic envelope statistics as a function of thrombi age: an in vitro study,” Ultrasound in Medicine and Biology, Vol. 41, No. 2, pp. 498-508, 2015, 1 (SCI IF=2.298) 
  3. Hsiao-Chien Chen, Yi-Ming Tu, Chung-Che Hou, Yu-Chen Lin,Ching-Hsiang Chen, Kuang-Hsuan Yang, "Direct electron transfer of glucose oxidase and dual hydrogen peroxide and glucose detection based on water-dispersible carbon nanotubes derivative," Analytica Chimica Acta 867 (2015) 83–91 (IF=4.712)
  4. Hsiao-Chien Chen, Yi-Ting Chen, Rung-Ywan Tsai, Min-Cheng Chen, Shi-Liang Chen, Min-Cong Xiao, Chien-Lun Chen, Mu-Yi Hua, "A sensitive and selective magnetic graphene composite-modified polycrystalline-silicon nanowire field-effect transistor for bladder cancer diagnosis"Biosensors and BioelectronicsVolume 66, 15 April 2015, Pages 198–207 (IF=7.476)
  5. Dong-Yu Gao, Ts-Ting Lin, Yun-Chieh Sung, Ya Chi Liu, Wen-Hsuan Chiang, Chih-Chun Chang, Jia-Yu Liu, Yunching Chen, "CXCR4-targeted lipid-coated PLGA nanoparticles deliver sorafenib and overcome acquired drug resistance in liver cancer", Biomaterials 67 (2015) 194-203 (IF=8.387)
  • 2014
  1. Hsiao-Chien Chen, Jian-Tai Qiu, Fu-Liang Yang, Yin-Chih Liu, Min-Cheng Chen, Rung-Ywan Tsai, Hung-Wei Yang, Chia-Yi Lin, Chu-Chi Lin, Tzong-Shoon Wu, Min-Cong Xiao, Yi-Ming Tu, Chia-Hua Ho, Chien-Chao Huang, Chao-Sung Lai, Mu-Yi Hua, "Magnetic-composite-modified polycrystalline-silicon nanowire field-effect transistor for vascular endothelial growth factor detection and cancer diagnosis", Analytical Chemistry, 86, 9443−9450 (2014).(IF=5.886)
  2. C.H. Lee, Y.H. Lin, S.H. Chang, C.D. Tai, S.J. Liu*, Y. Chu, C.J. Wang, M.Y. Hsu, H.Chang, G.J. Chang, K.C. Hung, M.J. Hsieh, F.C. Lin, I.C. Hsien, M.S. Wen, Y. Huang, Local Sustained Delivery of Acetylsalicylic Acid via Hybrid Stent/Biodegradable Nanofibers Reduces Adhesion of Blood Cells and Promotes Re-Endothelialization to the Denuded Artery, International Journal of Nanomedicine, 9, 311-326 (2014) (SCI IF=4.320)
  3. C.H. Lee, S.H. Chang, Y.H. Lin, S.J. Liu, C.J. Wang, M.Y. Hsu, K.C. Hung, Y.H. Yeh, W.J. Chen, I.C. Hsieh, M.S. Wen, "Acceleration of re-endothelialization and inhibition of neointimal formation using hybrid biodegradable nanofibrous rosuvastatin-loaded stents", Biomaterials, 35, 4417-4427 (2014) (SCI) (IF=8.387)
  4. Lan-Hsin Chuang, Yih-Shiou Hwang, Nan-Kai Wang, Yen-Po Chen,2,3 Laura Liu, Ling Yeung, Kuan-Jen Chen, Tun-Lu Chen, Wei-Chi Wu, and Chi-Chun Lai, "The Chorioretinal Damage Caused by Different Half Parameters of Photodynamic Therapy in Rabbits",JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS Volume 30, Number 8, 2014 (IF=1.754)
  5. Yu-Jen Lu, Chih-Wen Lin, Hung-Wei Yang, Kun-Ju Lin, Shiaw-Pyng Wey, Chia-Liang Sun, Kuo-Chen Wei, Tzu-Chen Yen, Ching-I Lin, Chen-Chi M. Ma, Jyh-Ping Chen. Biodistribution of PEGylated graphene oxide nanoribbons and their application in cancer chemo-photothermal therapy. Carbon 2014; 74:83-95. (IF=6.198)
  6. C.H. Chen, M.Y. Lee, V.B.H. Shyu, Y.C. Chen, C.T. Chen, J.P. Chen. 2014. Surface modification of polycaprolactone scaffolds fabricated via selective laser sintering for cartilage tissue engineering. Materials Science & Engineering C-Materials for Biological Applications, 40, 389-397.(IF=3.42)
  7. Hsiao-Chien Chen1, Jian-Tai Qiu1, Fu-Liang Yang1, Yin-Chih Liu, Min-Cheng Chen, Rung-Ywan Tsai, Hung-Wei Yang, Chia-Yi Lin, Chu-Chi Lin, Tzong-Shoon Wu, Min-Cong Xiao, Yi-Ming Tu, Chia-Hua Ho, Chien-Chao Huang, Chao-Sung Lai*, Mu-Yi Hua*, "Magnetic-composite-modified polycrystalline-silicon nanowire field-effect transistor for vascular endothelial growth factor detection and cancer diagnosis", Analytical Chemistry, Accepted, DOI: 10.1021/ac5001898 (2014).(IF=5.886)
  • 2013
  1. Lai PL, Chen LH, Chen WJ, Chu IM. Chemical and physical properties of bone cement for vertebroplasty. Biomedical Journal 2013; 36(4):162-167.
  2. Chiu-Yen Chung , Jen-Tsung Yang , Yung-Chih Kuo. Polybutylcyanoacrylate nanoparticles for delivering hormone response element-conjugated neurotrophin-3 to the brain of intracerebral hemorrhagic rats. Biomaterials 2013; 34:9717-9727
  3. Li-Fu Li, Yung-Yang Liu, Cheng-Ta Yang, Yueh Chien , Nae-Fang Twu, Mong-Lien Wang, Chien-Ying Wang, Chung-Chi Huang, Kuo-Chin Kao, Han-Shui Hsu, Cheng-Wen Wu, Shih-Hwa Chiou. Improvement of ventilator-induced lung injury by IPS cell-derived conditionedmedium via inhibition of PI3K/Akt pathway and IP-10-dependent paracrine regulation. Biomaterials 2013; 34: 78-91.
  4. Li-Fu Li, Pao-Hsien Chu, Cheng-Yiu Hung, Winston W.-Y. Kao, Meng-Chih Lin, Yung-Yang Liu and Cheng-Ta Yang. Lumican Regulates Ventilation-Induced Epithelial-Mesenchymal Transition Through Extracelluar Signal-Regulated Kinase Pathway. Chest 2013; 143(5): 1252-1260.
  5. Hung-Wei Yang, Hao-Li Liu, Meng-Lin Li, I-Wen Hsi, Chih-Tai Fan, Chiung-Yin Huang, Yu-Jen Lu, Mu-Yi Hua, Hsin-Yi Chou, Jiunn-Woei Liawf, Chen-Chi M. Ma, Kuo-Chen Wei. Magnetic gold-nanorod/ PNIPAAmMA nanoparticles for dual magnetic resonance and photoacoustic imaging and targeted photothermal therapy. Biomaterials 2013; 34: 5651-5660.
  6. Hung-Wei Yang, Yu-Jen Lu, Kun-Ju Lin, Sheng-Chieh Hsu, Chiung-Yin Huang, Shu-Han She, Hao-Li Liu, Chih-Wen Lin, Min-Cong Xiao, Shiaw-Pyng Wey, Pin-Yuan Chen, Tzu-Chen Yen, Kuo-Chen Wei, Chen-Chi M. Ma. EGRF conjugated PEGylated nanographene oxide for targeted chemotherapy and photothermal therapy. Biomaterials 2013; 34: 7204-7214.
  7. Ding-Wei Hong, Zhi-Teng Lai, Tsai-Sheng Fu, Tsung-Ting Tsai, I-Ming Chu, Po-Liang Lai. The influences of polycaprolactone-grafted nanoparticles on the properties of polycaprolactone composites with enhanced osteoconductivity. Composites Science and Technology 2013; 83:64-71.
  8. Hung-Wei Yang, Mu-Yi Hua, Tsong-Long Hwang, Kun-Ju Lin, Chiung-Yin Huang, Rung-Ywan Tsai, Chen-Chi M. Ma, Po-Hung Hsu, Shiaw-Pyng Wey, Peng-Wei Hsu, Pin-Yuan Chen, Yin-Cheng Huang, Yu-Jen Lu, Tzu-Chen Yen, Li-Ying Feng, Chih-Wen Lin, Hao-Li Liu, Kuo-Chen Wei. Non-Invasive Synergistic Treatment of Brain Tumors by Targeted Chemotherapeutic Delivery and Amplified Focused Ultrasound-Hyperthermia Using Magnetic Nanographene Oxide. ADVANCED MATERIALS 2013; 25(26): 3605-3611.
  9. Nan-Kai Wang, Chi-Chun Lai, Chi-Hsiu Liu, Lung-Kun Yeh, Chai Lin Chou, Jian Kong, Takayuki Nagasaki, Stephen H. Tsang and Chung-Liang Chien. Origin of fundus hyperautofluorescent spots and their role in retinal degeneration in a mouse model of Goldmann-Favre syndrome. Disease Models & Mechanisms 2013; 6: 1113-1122.
  10. C. L. Sun, W. C. Cheng, T. K. Hsu, C. W. Cheng, J. L. Chang, J. M. Zen, "Ultrasensitive and highly stable nonenzymatic glucose sensor by a CuO/graphene-modified screen-printed carbon electrode integrated with flow-injection analysis" Electrochem. Commun. 30, 91 (2013).
  11. Lai, P.-L., Tsai-Yu Lin, C., Hong, D.-W., Yang, S.-R., Chang, Y.-H., Chen, L.-H., Chen, W.-J., Chu. I.-M. (2013) Development of bioactive thermosensitive polymer-ceramic composite as bone substitute. Chemical Engineering Science 89 , pp. 133-141.
  12. Lai, P.-L., Hong, D.-W., Chu, I.-M., Chen, W.-J., Chen, L.-H., Niu, C.-C., Fu, T.-S., Tsai, T.-T., Liao, J.-C. (2013) Polyanhydride copolymer and bioceramic composites as bone substitutes. Formosan Journal of Musculoskeletal Disorders 4 (1) , pp. 6-10.
  13. Hong,D.-W., Lai,P.-L., Ku, K.-L., Lai, Z.-T., Chu,I.-M.(2013) Biodegradable in situ gel-forming controlled vancomycin delivery system based on a thermosensitive mPEG-PLCPPA hydrogel. Polymer Degradation and Stability 98 (9), 1578-1585.
  14. Hong,D.-W., Lai, Z.-T., Fu, T.-S., Tsai, T.-T., Chu, I.-M., Lai,P.-L. (2013) The influences of polycaprolactone-grafted nanoparticles on the properties of polycaprolactone composites with enhanced osteoconductivity. Composites Science and Technology 83 , pp. 64-71.
  15. Hwang YS, Chiang PR, Hong WH, Chiao CC, Chu IM, Hsiue GH, Shen CR. Study in vivo Intraocular Biocompatibility of in situ Gelation Hydrogels: Poly(2-ethyl oxazoline)-block-poly(ε-caprolactone)-block-poly(2-ethyl oxazoline) Copolymer, Matrigel and Pluronic F127. PLoS One 2013 July; 8(7): e67495
  16. Li-Fu Li, Yung-Yang Liu, Cheng-Ta Yang, Yueh Chien, Nae-Fang Twu, Mong-Lien Wang,Chien-Ying Wang, Chung-Chi Huang, Kuo-Chin Kao, Han-Shui Hsu, Cheng-Wen Wu,Shih-Hwa Chiou. (2013) “Improvement of ventilator-induced lung injury by IPS cell-derived conditioned medium via inhibition of PI3K/Akt pathway and IP-10-dependent paracrine regulation.” Biomaterials 34:78-91
  17. Yung-Yang Liu, Li-Fu Li, Cheng-Ta Yang, Kai-Hsi Lu, Chung-Chi Huang, Kuo-Chin Kao, Shih-Hwa Chiou. Suppressing NF-kB and NKRF pathways by induced pluripotent stem cell therapy in mice with ventilator-induced lung injury. PLoS One 2013,8(6):e66760 (SCI; IF=3.73; Multidisciplinary Sciences 7/56).
  18. Chiu-Yen Chung, Jen-Tsung Yang, Yung-Chih Kuo. (2013) “Polybutylcyanoacrylate nanoparticle-mediated neurotrophin-3 gene delivery for differentiating iPS cells into neurons” Biomaterials 34,5562-5570
  19. Jih-Chao Yeh , Huei-Hung Yang, Ya-Ting Hsu, Chao-Ming Su, Tsong-Hai Lee, Shyh-Liang Lou, (2013)”Synthesis and characteristics of biodegradable and temperature responsive polymeric micelles based on poly(asparticacid)-g-poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide).”Colloids and Surfaces A: Physicochem. Eng. Aspects 421,1–8
  20. Hung-Wei Yang, Yu-Jen Lu, Kun-Ju Lin, Sheng-Chieh Hsu, Chiung-Yin Huang, Shu-Han She, Hao-Li Liu, Chih-Wen Lin, Min-Cong Xiao, Shiaw-Pyng Wey, Pin-Yuan Chen, Tzu-Chen Yen, Kuo-Chen Wei, Chen-Chi M. Ma,“EGRF conjugated PEGylated nanographene oxide for targeted chemotherapy and photothermal therapy” Biomaterials ,34(29), 7204-7214(2013).
  21. Hung-Wei Yang, Mu-Yi Hua, Tsong-Long Hwang, Kun-Ju Lin, Chiung-Yin Huang, Rung-Ywan Tsai, Chen-Chi M. Ma, Po-Hung Hsu, Shiaw-Pyng Wey, Peng-Wei Hsu, Pin-Yuan Chen, Yin-Cheng Huang, Yu-Jen Lu, Tzu-Chen Yen, Li-Ying Feng, Chih-Wen Lin, Hao-Li Liu and Kuo-Chen Wei, "Noninvasive synergistic treatment of brain tumor by targeted chemotherapeutic delivery and amplified focused ultrasound-hyperthermia using magnetic nanographene oxide", Advanced Materials, 25(26), 3605–3611 (2013). (IF = 14.829, Filtered by Matericals Science, Multidisciplinary, 6/239) (1 Equal Contribution)
  22. Hsiao-Chien Chen, Yen-Hsuan Chen, Shi-Liang Chen, Yaw-Terng Chern, Rung-Ywan Tsai, Mu-Yi Hua, Preparation of highly conjugated water-dispersible graphene- butyric acid for the enhancement of electron transfer within polyamic acid- benzoxazole: potential applications in electrochemical sensing", Biosensors and Bioelectronics, 46, 84–90 (2013)
  23. Hsiao-Chien Chen, Rung-Ywan Tsai, Yen-Hsuan Chen, Ren-Shen Lee, Mu-Yi Hua, A colloidal suspension of nanostructured poly(N-butylbenzimidazole)-graphene sheets with high oxidase yield for analytical glucose and choline detections. Analytica Chimica Acta, 792, 101– 109(2013)
  24. Ngoc Thi Thanh Tran, Tzu-Hao Wang, Chiao-Yun Lin, Yian Tai, Synthesis of methotrexate-conjugated gold nanoparticles with enhanced cancer therapeutic effect.Biochem. Eng. J. (2013)
  25. Hung-Wei Yang, Mu-Yi Hua, Shi-Lian Chen, Rung-Ywan Tsai, "Reusable biosensor based on high magnetization carboxyl-modified graphene oxide with intrinsic hydrogen peroxide catalytic activity for glucose detection", Biosensors & Bioelectronics (2013), (IF = 5.602, Filtered by Electrochemistry, 1/27) (1 Equal Contribution).
  26. Juang JH, Shen CR (equal to first), Wang, JJ, Kuo CH, Chien YW, Kuo HY, Chen FR, Chen MH, Yen TC, Tsai ZT. Magnetic resonance imaging of mouse islet grafts labeled with novel chitosan-coated superparamagnetic Iron Oxide nanoparticles. PLoS One 2013 8(4):e62626. SCI=3.730 (MULTIDISCIPLINARY SCIENCES, 12.50%)
  27. Lin YH, Chang HM, Chang FP, Shen CR (equal to second), Liu CL, Mao WY, Lin CC, Shen CN. Protoporphyrin IX accumulation disrupts mitochondrial dynamics in ABCG2-deficient hepatocytes. FEBS Letters 587 (2013) 3202–3209
  • 2012
  1. A-H Liao, H-L Liu, C-H Su, M-Y Hua, H-W Yang, Y-T Weng, P-H Hsu, S-M Huang, S-Y Wu, H-El Wang, T-C Yen and P-C Li, (2012) Paramagnetic Perfluorocarbon-Filled Albumin-(Gd-DTPA) Microbubbles for the Induction of Focused-Ultrasound-Induced Blood–Brain Barrier Opening and Concurrent MR and Ultrasound Imaging. Physics in Medicine and Biology 57 (9), 2787-2802.
  2. Wang CH, Hwang YS (Co-first), Chiang PR, Shen CR, Hong WH, Hsiue GH. (2012)Extended Release of Bevacizumab by Thermosensitive Biodegradable and Biocompatible Hydrogel. Biomacromolecules 13(1),40-8.
  3. Lai, P.-L., Hong, D.-W., Liu, T.-H., Lai, Z.-T., Cheng, M.-H., Chen, L.-H., Chen, W.-J., Chu, I.-M. (2012) Validity of poly(1, 6-bis-(p-carboxyphenoxy hexane)-co-(sebacic anhydride)) copolymer in biomedical application. Journal of Applied Polymer Science, DOI:10.1002/APP.38597.
  4. Po-Liang Lai, Ding-Wei Hong, Carl Tsai-Yu Lin, Lih-Huei Chen, Wen-Jer Chen, I-Ming Chu. Effect of mixing ceramics with a thermosensitive biodegradable hydrogel as composite graft. Composites: Part B 43 (2012) 3088–3095.
  5. Po-Liang Lai, Ding-Wei Hong, Tsang-Hao Liu, Zhi-Teng Lai, Ming-Huei Cheng, Lih-Huei Chen, Wen-Jer Chen, I -Ming Chu. Validity of Poly (1, 6-bis-(p-carboxyphenoxy hexane)-co-(sebacic anhydride)) copolymer in biomedical application. Journal of Applied Polymer Science (accepted)
  6. Wang CH, Hwang YS, Chiang PR, Shen CR, Hong, WH, Hsiue GH. Extended release of Bevacizumab by thermosensitive biodegradable and biocompatible hydrogel. Biomacromolecules 2012;13(1):40-8. Epub 2011 Dec 6. dx.doi.org/ 10.1021/ bm 2009558.
  7. H-W Yang, M-Y Hua, H-L Liu, R-Y Tsai, S-T Pang, P-H Hsu, H-J Tang, T-C Yen, C-K Chuang, “An epirubicin-conjugated nanocarrier with MRI function to overcome lethal multidrug-resistant bladder cancer,” Biomaterials, Vol. 33, pp. 3919-3930, 2012.
  8. A-H Liao, H-L Liu, C-H Su, M-Y Hua, H-W Yang, Y-T Weng, P-H Hsu, S-M Huang, S-Y Wu, H-El Wang, T-C Yen and P-C Li, "Paramagnetic Perfluorocarbon-Filled Albumin-(Gd-DTPA) Microbubbles for the Induction of Focused-Ultrasound-Induced Blood–Brain Barrier Opening and Concurrent MR and Ultrasound Imaging", Physics in Medicine and Biology, in press (2012). (IF = 3.056, Filtered by Engineering, Biomedical, 11/69)
  9. Hung-Wei Yang1, Mu-Yi Hua1,*, Hao-Li Liu1 , Rung-Ywan Tsai, Cheng-Keng Chuang, Po-Chun Chu, Pei-Yi Wu, Ying-Hsu Chang, Heng-Chang Chuang, Kai-Jie Yu, See-Tong Pang*, "Cooperative Dual-activity Targeted Nanomedicine for Specific and Effective Prostate Cancer Therapy", ACS Nano, 6(2), 1795-1805 (2012).
  10. Hao-Li Liu, Hung-Wei Yang, Mu-Yi Hua, and Kuo-Chen Wei*, "Enhanced Therapeutic Agent Delivery via MRI-Monitored Focused Ultrasound Blood-Brain Barrier Disruption for Brain Tumor Treatment: An Overview of the current Preclinical Status", Neurosurgical Focus, 32(1), 1-12 (2012). (SCI, IF = 2.348, Filtered by Surgery, 43/187).
  11. Rong-Jia Su, Hong-Wei Yang, Yann-Lii Leu, Mu-Yi Hua, Ren-Shen Lee*, "Synthesis and characterization of amphiphilic functional polyesters by ring-opening polymerization and click reaction", Reactive & Functional Polymers, 72, 36-44 (2012). (IF = 2.546, Filtered by Polymer Science, 16/79).
  12. Yu-Jen Lu, Hung-Wei Yang, Sheng-Che Hung, Chiung-Yin Huang, Shin-Ming Li, Chen-Chi M. Ma, Pin-Yuan Chen, Hong-Chieh Tsai, Kuo-Chen Wei, Jyh-Ping Chen, "Improving thermal stability and treatment efficacy of BCNU to glioma cells using PAA-functionalized graphene oxide", International Journal of Nanomedicine, 7, 1737-1747 (2012).
  13. Hung-Wei Yang, Mu-Yi Hua, Kun-Ju Lin, Shiaw-Pyng Wey, Rung-Ywan Tsai, Siao-Yun Wu, Yi-Ching Lu, Hao-Li Liu, Tony Wu*, Yunn-Hwa Ma, "Bioconjugation of recombinant tissue plasminogen activator to magnetic nanocarriers for targeted thrombolysis", International Journal of Nanomedicine 7, 5159-5173 (2012).
  14. Hung-Wei Yang, Mu-Yi Hua, Hao-Li Liu, Chiung-Yin Huang, Kuo-Chen Wei*, "Potential of magnetic nanoparticles for drug delivery ", Nanotechnology, Science and Applications 5, 73-86 (2012) (invited review).
  15. Mu-Yi Hua, Yu-Chen Lin, Rung-Ywan Tsai, Hsiao-Chien Chen, "Water dispersible 1-one-butyric acid-functionalised multi-walled carbon nanotubes for enzyme immobilisation and glucose sensing", J. Mater. Chem., 22(6), 2566-2574 (2012).
  • 2011
  1. Y.P. Fang. Topical delivery of DNA oligonucleotide to induce p53 generation in the skin via thymidine dinucleotide (pTT)-encapsulated liposomal carrier. International Journal of Nanomedicine. 6: 3373-3381, 2011
  2. Mu-Yi Hua, Hung-Wei Yang, Hao-Li Liu, Rung-Ywan Tsai, See-Tong Pang, Kun-Lung Chuang, Yu-Sun Chang, Tsong-Long Hwang, Ying-Hsu Chang, Heng-Chang Chuang, Cheng-Keng Chuang. Superhigh-magnetization nanocarrier as a doxorubicin delivery platform for magnetic targeting therapy. Biomaterials. 2011 32, 8999-9010. IF = 7.882
  3. Andre’s Rodriguez, David Chwei-Chin Chuang, Kuang-Te Chen, Ruei-Feng Chen, Rong-Kuo Lyu, Yu-Shien Ko (2011) Comparative Study of Single, Double and Triple Nerve Transfer to A Common Target --- Experimental Study of Rat Brachial Plexus. Plastic & Reconstructive Surgery. 2011 Mar;127(3):1155-62. IF=3.382
  4. Wei-Chi Wu, Chih-Chun Chen, Chi-Hsien Liu, Nan-Kai Wang, Kuan-Jen Chen, Tun-Lu Chen, Yih-Shiou Hwang, Lien-Min Li, and Chi-Chun Lai (2011) Plasmin Treatment Accelerates Vascular Endothelial Growth Factor Clearance from Rabbit Eyes. Investigative Ophthalmology & Visual Science, August 2011, Vol. 52, No. 9: 6162-67. IF=3.597
  5. Mu-Yi Hua, Hsiao-Chien Chen, Rung-Ywan Tsai, Sung-Cheng Hu, Cheng-Der Chiang, Pai-Jung Chang, "Preparation of polybenzimidazole-carboxylated multiwall carbon nanotube composite for intrinsic sensing of hydrogen peroxid", J. Phys. Chem. C, in press (2011). IF=4.805
  6. Hung-Wei Yang, Mu-Yi Hua, Hao-Li Liu, Chiung-Yin Huang, Rung-Ywan Tsai, Yu-Jen Lu, Ju-Yu Chen, Hsiang-Jun Tang, Jia-Shin Wu, Han-Yi Hsien, Yu-Sun Chang, Tzu-Chen Yen, Pin-Yuan Chen, Kuo-Chen Wei, "Self-protecting core-shell magnetic nanoparticles for targeted, traceable, long half-life delivery of BCNU to gliomas", Biomaterials, 32, 6523-6532 (2011). (IF = 7.404, Filtered by Materials Science, Biomaterials, 2/25) (1 Equal Contribution)
  7. Mu-Yi Hua, Hsiao-Chien Chen, Cheng-Keng Chuang, Rung-Ywan Tsai, Jyh-Long Jeng, Hung-Wei Yang, Yaw-Terng Chern, "The intrinsic redox reactions of polyamic acid derivatives and their application in hydrogen peroxide sensor", Biomaterials, 32, 4885-4895 (2011). IF=7.404
  8. Mu-Yi Hua, Hsiao-Chien Chen, Rung-Ywan Tsai, and Chao-Sung Lai, "A novel polybenzimida- zole-modified gold electrode for the analytical determination of hydrogen peroxide", Talanta, 85, 631-637 (2011). IF=3.794
  9. Mu-Yi Hua, Chun-Jen Chen, Hsiao-Chien Chen, Rung-Ywan Tsai, Wen Cheng, Chun-Lin Cheng, Yin-Chih Liu, "Preparation of a porous composite film for the fabrication of a highly sensitive hydrogen peroxide sensor", Sensors, 11, 5873-5885 (2011). IF=1.739
  10. Mu-Yi Hua, Hsiao-Chien Chen, Rung-Ywan Tsai, Yann-Lii Leu, Yin-Chih Liu and Jinn-Tsyy Lai, "Synthesis and characterization of carboxylated polybenzimidazole and its use as a highly sensitive and selective enzyme-free H2O2 sensor", J. Mater. Chem., 21(20), 7254-7262 (2011). IF=5.968
  11. Mu-Yi Hua, Hsiao-Chien Chen, Rung-Ywan Tsai, Yu-Chen Lin, Leeyih Wang, "A novel biosensing mechanism based on poly(N-butyl benzimidazole) modified gold electrode for the detection of hydrogen peroxide", Analytica Chimica Acta, 693, 114-120 (2011). IF=4.555
  12. Mu-Yi Hua, Hsiao-Chien Chen, Rung-Ywan Tsai, Yu-Chen Lin, "A novel amperometric sensor for peracetic acid based on a polybenzimidazole-modified gold electrode", Electrochimica Acta, 56, 4618-4623 (2011). IF=3.832
  13. Mei-Hui Lin, Fang-Rong Chang, Mu-Yi Hua, Yang-Chang Wu, Shih-Tung Liu, "Inhibitory effects of 1,2,3,4,6- penta-O-galloyl-β-D-glucopyranose on biofilm 3 formation by Staphylococcus aureus", Antimicrob. Agents Chemother., 55, 1021-1027 (2011). IF=4.841
  14. Mu-Yi Hua, Hao-Li Liu, Hung-Wei Yang, Pin-Yuan Chen, Rung-Ywan Tsai, Chiung-Yin Huang, I-Chou Tseng, Lee-Ang Lyu, Chih-Chun Ma, Hsiang-Jun Tang , Tzu-Chen Yen, Kuo-Chen Wei, "The effectiveness of a magnetic-nanoparticle-based delivery system for BCNU in the treatment of gliomas", Biomaterials, 32, 516-527 (2011). IF=7.404
  15. Li-Fu Li, Bao-Xiang Chen, Ying-Huang Tsai, Winston W.-Y. Kao, Cheng-Ta Yang, Pao-Hsien Chu*. Lumican expression in diaphragm induced by mechanical ventilation. PLoS One 2011, 6(9):e24692 (SCI; IF=4.092; Biology 12/85)
  16. Li-Fu Li, Mei-Ling Tien, Sum-Yee Leung, Meng-Chih Lin*. High tidal volume mechanical ventilation elicits increased activity in protein kinase B and c-Jun NH2-terminal kinase pathways in mouse diaphragm. Intensive Care Med 2011, 37(12):2015-2022 (SCI; IF=5.399; Critical Care Medicine 3/26)
  17. Shen CR (correspondence), Juang JH, Tsai ZT, Wu ST, Tsai FY, Wang JJ, Yen TC. Preparation, characterization and application of superparamagnetic iron oxide encapsulated with N-[(2-hydroxy-3-trimethylammonium) propyl] chitosan chloride. Carbohydr Polym 2011 Mar; 84(1): 781- 787.
  18. Shen CR, Wu ST, Tsai ZT, Wang JJ, Yen TC, Tsai JS, Liu CL. Characterization of the Quaternized chitosan-stabilized iron-oxide nanoparticles as a novel potential MRI contrast agent for cell tracking. Poly International 2011 Jun 60(6): 945-950.
  • 2010
  1. Chien-Yu Hsiao, Chun-Hsun Huang, Sindy Hu, Yu-Shien Ko, Hsin-Ching Sung, Shih-Yi Huang (2010) Skin Pretreatment with Lasers Promotes the Transdermal Delivery of Vitamin C Derivatives. Lasers in Medical Science. 2010 Dec 1. IF=2.004
  2. Lung-Kun Yeh, Chia-Yang Liu, Winston W.-Y. Kao, Chang-Jen Huang, Fung-Rong Hu, Chung-Liang Chien, and I-Jong Wang. (2010) Knockdown of Zebrafish Lumican Gene (zlum) Causes Scleral Thinning and Increased Size of Scleral Coats. Journal of Biological Chemistry 285(36): 28141-28155. IF=4.773
  3. Pin-Yuan Chen, Hao-Li Liu, Mu-Yi Hua, Hung-Wei Yang, Chiung-Yin Huang, Po-Chun Chu, Lee-Ang Lyu, I-Chou Tseng, Li-Ying Feng, Hong-Chieh Tsai, Shu-Mei Chen, Yu-Jen Lu, Jiun-Jie Wang, Tzu-Chen Yen, Yunn-Hwa Ma, Tony Wu, Jyh-Ping Chen, Jih-Ing Chuang, Jyh-Wei Shin, Chuen Hsueh, and Kuo-Chen Wei.(2010) Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatment. Neuro Oncol 12(10): 1050-1060. IF=5.723
  4. Mu-Yi Hua, Hung-Wei Yang, Cheng-Keng Chuang, Rung-Ywan Tsai, Wen-Jauh Chen, Kun-Lung Chuang, Ying-Hsu Chang, Heng-Chang Chuang, See-Tong Pang.(2010) Magnetic-nanoparticle-modified paclitaxel for targeted therapy for prostate cancer. Biomaterials 31(28): 7355-7363. IF=7.404
  5. Hao-Li Liu, Mu-Yi Hua, Hung-Wei Yang, Chiung-Yin Huang, Po-Chun Chu, Jia-Shin Wu, I-Chou Tseng, Jiun-Jie Wang, Tzu-Chen Yen, Pin-Yuan Chen, and Kuo-Chen Wei.(2010) Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain. PNAS 107(34): 15205-15210. IF=9.681
  6. J.-T. Yeh, L.-K. Yeh, S.-M. Jung, T.-J. Chang, H.-H. Wu, T.-F. Shiu, C.-Y. Liu, W.W.-Y. Kao, P.-H. Chu.(2010) Impaired Skin Wound Healing in Lumican-null Mice. British Journal of Dermatology DOI: 10.1111/j.1365-2133.2010.10008.x. IF=3.666
  7. Ming-Hui Sun, Jong-Hwei Su Pang, Show-Li Chen, Wen-Hua Han, Tsung-Chuan Ho, Kuan-Jen Chen, Ling-Yuh Kao, Ken-Kuo Lin, and Yeou-Ping Tsao. (2010) Retinal Protection from Acute Glaucoma-Induced Ischemia-Reperfusion Injury through Pharmacologic Induction of Heme Oxygenase-1. IOVS, September 2010, Vol. 51, No. 9: 4798–4808. IF=3.597
  8. H-L Liu, M-Y Hua, H-W Yang, C-Y Huang, P-C Chu, J-S Wua, I-C Tseng, J-J Wang, T-C Yen, P-Y Chen, and K-C Wei, “Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain,” 2010 Aug 24;107(34):15205-10. doi: 10.1073/pnas.1003388107. Epub 2010 Aug 9. IF=9.681
  • 2009
  1. Young JD, Martel J, Young L, Wu C-Y, Young A, et al. (2009) Putative NanobacteriaRepresent Physiological Remnants and Culture By-Products of Normal Calcium Homeostasis. PLoS ONE 4(2): e4417. doi:10. 1371/journal.pone.0004417. IF=4.092
  2. Young JD, Martel J, Young D, Young A, Hung C-M, et al. (2009) Characterization of Granulations of Calcium and Apatite in Serum as Pleomorphic Mineralo-Protein Complexes and as Precursors of Putative Nanobacteria. PLoS ONE 4(5): e5421. dol:10. 1371/1/ journal.pone.0005421. IF=4.092
  3. Jyh-Ping Chen, Kuo-Hsu Ho, Yi-Ping Chiang, Kuo-Wei Wu., (2009) Fabrication of electrospun poly(methyl methacrylate) nanofibrous membranes by statistical approach for application in enzyme immobilization, J. Membr. Sci., doi:10,1016/j.memsci.2009.05.002. IF=3.850
  • 2008
  1. Jan Martel , John Ding-E Young(2008) Purported nanobacteria in human blood as calcium carbonate nanoparticles. PNAS 2008 105:5549-5554.
  2. Jyh-Ping Chen, Gwo-Yun Chang, Jan-Kan Chen. Electrospun collagen/chitosan nanofibrous membrane as wound dressing. Colloids and Surfaces A: Physicochem. Eng. Aspects 313–314 (2008) 183–188.
  • 2007
  1. Liu HW, Chen CH, Tsai CL, Lin IH, Hsiue GH. Heterobifunctional poly (ethylene glycol)-tethered bone morphogenetic protein-2-stimulated bone marrow mesenchymal stromal cells differentiation and osteogenesis. Tissue Engineering 2007; 13:11131124. (SCI, 2006 IF: 3.725) (selected as cover art)
  • 2006
  1. Hsieh SY, Shih TC, Yeh CY, Lin CJ, Chou YY, Lee YS.Comparative proteomic studies on the pathogenesis of human ulcerative colitis. Proteomics. 2006. Aug 31;6(19):5322-5331.
  2. Liu HW, Chen CH, Tsai CL, Hsiue GH. Targeted delivery system for juxtacrine signaling growth factor based on rhBMP-2-mediated carrier-protein conjugation. Bone. 2006 Oct;39(4):825-36. Epub 2006 Jun 16.
  • 2005
  1. C.H. Chen, H.W. Liu, C.L. Tsai, W.J. Chen, C.H. Shih and G.H. Hsiue, (2005), “Osteoinduction and osteogenesis of a novel bone morphogenetic protein-conjugated poly-(D, L-lactide-co-glycolide), hydroxyapatite and collagen composite bone substitute”, Journal of Orthopaedic Surgery Taiwan, 22: 131-141.　

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