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                                       研 究 成 果  


The papers we have published under this grant are listed as follows.

  1. Hsu JT, Chen TD, Chuang HC, Huang SC, Le PH, Chen TH, Lin CJ, Yeh TS. Vascular endothelial growth factor expression is an independent poor prognostic factor for human epidermal growth factor receptor 2 positive gastric cancer.  J Surg Res. 2017 Feb;208:40-50. doi: 10.1016/j.jss.2016.09.004.
  2. Hsu JT, Liao JA, Chuang HC, Chen TD, Chen TH, Kuo CJ, Lin CJ, Chou WC, Yeh TS, Jan YY. Palliative gastrectomy is beneficial in selected cases of metastatic gastric cancer.  BMC Palliat Care. 2017 Mar 14;16(1):19. doi: 10.1186/s12904-017-0192-1.
  3. Wei KC, Chen CY, Feng LY, Huang WT, Chen CH, Hsu PW, Wang K, Hood LE, Chen LY. The rs16906252:C>T SNP is not associated with increased overall survival or temozolomide response in a Han-Chinese glioma cohort. PLoS One. 2017 Jun 2;12(6):e0178842. doi: 10.1371/journal.pone.0178842.
  4. Chao A, Lin CY, Chao AN, Tsai CL, Chen MY, Lee LY, Chang TC, Wang TH, Lai CH, Wang HS. Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies. Oncotarget. 2017 Aug 10;8(43):74434-74450. doi: 10.18632/oncotarget.20158.
  5. Huang CC, Chang PH, Wu PW, Wang CH, Fu CH, Huang CC, Tseng HJ, Lee TJ. Impact of nasal symptoms on the evaluation of asthma control. Medicine (Baltimore). 2017 Feb;96(8):e6147. doi: 10.1097/MD.0000000000006147.
  6. Yeh CT, Liang KH, Chang ML, Hsu CW, Chen YC, Lin CL, Lin WR, Lai MW. Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008-2012. Emerg Infect Dis. 2017 May;23(5):820-821. doi: 10.3201/eid2305.161894.
  7. Lin JW, Chang ML, Hsu CW, Chen YC, Liang KH, Huang YH, Lin CC, Yeh CT. Acute exacerbation of hepatitis C in hepatocellular carcinoma patients receiving chemotherapy. J Med Virol. 2017 Jan;89(1):153-160. doi: 10.1002/jmv.24595.
  8. Lin YT, Chien KY, Wu CC, Chang WY, Chu LJ, Chen MC, Yeh CT, Yu JS. Super-SILAC mix coupled with SIM/AIMS assays for targeted verification of phosphopeptides discovered in a large-scale phosphoproteome analysis of hepatocellular carcinoma. J Proteomics. 2017 Mar 22;157:40-51. doi: 10.1016/j.jprot.2017.02.005.
  9. Wu RC, Chao AS, Lee LY, Lin G, Chen SJ, Lu YJ, Huang HJ, Yen CF, Han CM, Lee YS, Wang TH, Chao A. Massively parallel sequencing and genome-wide copy number analysis revealed a clonal relationship in benign metastasizing leiomyoma. Oncotarget. 2017 Jul 18;8(29):47547-47554. doi: 10.18632/oncotarget.17708.
  10. Jusakul A, Cutcutache I, Yong CH, Lim JQ, Huang MN, Padmanabhan N, Nellore V, Kongpetch S, Ng AWT, Ng LM, Choo SP, Myint SS, Thanan R, Nagarajan S, Lim WK, Ng CCY, Boot A, Liu M, Ong CK, Rajasegaran V, Lie S, Lim AST, Lim TH, Tan J, Loh JL, McPherson JR, Khuntikeo N, Bhudhisawasdi V, Yongvanit P, Wongkham S, Totoki Y, Nakamura H, Arai Y, Yamasaki S, Chow PK, Chung AYF, Ooi LLPJ, Lim KH, Dima S, Duda DG, Popescu I, Broet P, Hsieh SY, Yu MC, Scarpa A, Lai J, Luo DX, Carvalho AL, Vettore AL, Rhee H, Park YN, Alexandrov LB, Gordân R, Rozen SG, Shibata T, Pairojkul C, Teh BT, Tan P.Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma. Cancer Discov. 2017 Oct;7(10):1116-1135. doi: 10.1158/2159-8290.CD-17-0368.
  11. Ng AWT, Poon SL, Huang MN, Lim JQ, Boot A, Yu W, Suzuki Y, Thangaraju S, Ng CCY, Tan P, Pang ST, Huang HY, Yu MC, Lee PH, Hsieh SY, Chang AY, Teh BT, Rozen SG. Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia. SciTransl Med. 2017 Oct 18;9(412). pii: eaan6446. doi: 10.1126/scitranslmed.aan6446.
  12. Lee TJ, Fu CH, Wang CH, Huang CC, Huang CC, Chang PH, Chen YW, Wu CC, Wu CL, Kuo HP. Impact of chronic rhinosinusitis on severe asthma patients. PLoS One. 2017 Feb 15;12(2):e0171047. doi: 10.1371/journal.pone.0171047.
  13. Liu YS, Lin HY, Lai SW, Huang CY, Huang BR, Chen PY, Wei KC, Lu DY. MiR-181b modulates EGFR-dependent VCAM-1 expression and monocyte adhesion in glioblastoma. Oncogene. 2017 Aug 31;36(35):5006-5022. doi: 10.1038/onc.2017.129.
  14. Chang KP, Wang CI, Pickering CR, Huang Y, Tsai CN, Tsang NM, Kao HK, Cheng MH, Myers JN. Prevalence of promoter mutations in the TERT gene in oral cavity squamous cell carcinoma. Head Neck. 2017 Jun;39(6):1131-1137. doi: 10.1002/hed.24728.
  15. Kao HK, Abdelrahman M, Huang Y, Tsai CH, Barrera MJ, Tsang NM, Couves AJ, Cheng MH, Chang KP. Multiple concomitant oral cavity cancers: Incidence, management, and outcomes. J SurgOncol. 2017 Jun;115(7):835-841. doi: 10.1002/jso.24600.
  16. Kuo IC, Kao HK, Huang Y, Wang CI, Yi JS, Liang Y, Liao CT, Yen TC, Wu CC, Chang KP. Endoplasmic reticulum aminopeptidase 2 involvement in metastasis of oral cavity squamous cell carcinoma discovered by proteome profiling of primary cancer cells. Oncotarget. 2017 Jun 27;8(37):61698-61708. doi: 10.18632/oncotarget.18680.
  17. Liang KH, Yeh TS, Wu RC, Yeh CN, Yeh CT. GALNT14 genotype is associated with perineural invasion, lymph node metastasis and overall survival in resected cholangiocarcinoma.OncolLett. 2017 Jun;13(6):4215-4223. doi: 10.3892/ol.2017.5991.
  18. Chen MY, Pai PC, Jung SM, Chuang CC, Chang CN, Wei KC.  Prognostic effects of O6-Methylguanine DNA methyltransferase promoter hypermethylation in high-grade glioma patients with carmustine wafer implants. Formos J Surg. 2017. 50(2):45.
  19. Hsu JT, Chen TD, Chuang HC, Huang SC, Le PH, Chen TH, Lin CJ, Yeh TS. Vascular endothelial growth factor expression is an independent poor prognostic factor for human epidermal growth factor receptor 2 positive gastric cancer.  J Surg Res. 2017 Feb;208:40-50. doi: 10.1016/j.jss.2016.09.004.
  20. Hsu JT, Wang CW, Le PH, Wu RC, Chen TH, Chiang KC, Lin CJ, Yeh TS. Clinicopathological characteristics and outcomes in stage I–III mucinous gastric adenocarcinoma: a retrospective study at a single medical center. World J SurgOncol. 2016 Apr 26;14:123. doi: 10.1186/s12957-016-0886-5.
  21. Wang TH, Yu CC, Lin YS, Chen TC, Yeh CT, Liang KH, Shieh TM, Chen CY, Hsueh C. Long noncoding RNA CPS1-IT1 suppresses the metastasis of hepatocellular carcinoma by regulating HIF-1α activity and inhibiting epithelial-mesenchymaltransition.Oncotarget. 2016 Jul 12;7(28):43588-43603. doi:10.18632/oncotarget.9635.
  22. Huang YH, Tseng YH, Lin WR, Hung G, Chen TC, Wang TH, Lee WC, Yeh CT. HBV polymerase overexpression due to large core gene deletion enhances hepatoma cell growth by binding inhibition of microRNA-100. Oncotarget. 2016 Feb 23;7(8):9448-61. doi: 10.18632/oncotarget.7021.
  23. Wang TH, Yeh CT, Ho JY, Ng KF, Chen TC. OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. MolCarcinog. 2016 Apr;55(4):366-75. doi: 10.1002/mc.22286. Epub 2015 Feb 8.
  24. Chao A, Lin CY, Chao AN, Tsai CL, Chen MY, Lee LY, Chang TC, Wang TH, Lai CH, Wang HS. Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies. Oncotarget. 2017 Aug 10;8(43):74434-74450. doi: 10.18632/oncotarget.20158.
  25. Wang TH, Yeh CT, Ho JY, Ng KF, Chen TC. OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. MolCarcinog. 2016 Apr;55(4):366-75. doi: 10.1002/mc.22286. Epub 2015 Feb 8.
  26. Wang CJ, Chen TC, Lin JH, Huang PR, Tsa HJ. One-step preparation of hydrophilic carbon nanofiber containing magnetic Ni nanoparticles materials and their application in drug delivery. J. Colloid Interface Sci. 2015 Feb;440:179–188.
  27. Dutta A, Huang CT, Chen TC, Lin CY, Chiu CH, Lin YC, Chang CS, He YC. IL-10 inhibits neuraminidase-activated TGF-b and facilitates Th1 phenotype during early phase of infection. Nat. Commun.2015 Mar;6:6374. doi: 10.1038/ncomms7374.
  28. Huang CT , Dutta A, Chen TC, Lin CY, Lin YC, Chang CS, He YC. Th17 deviation under influence of Th1 response attenuates the inflammation in late phase of influenza virus infection. The J. Immunol. 2015 May ;194: 148.6.
  29. Huang CT, Dutta A, Chen TC, Lin CY, Chiu CH, Lin YC, Chang CS, He YC. IL-10 inhibits neuraminidase activated-TGF-β and facilitates Th1 phenotype during early phase of infection. The J. Immunol. 2015 May ;194: 74.6.
  30. Hsieh CY, Chang MY, Chen KH, Jenq CC, Li YJ, Chen TC, Yang CW, Chen YM. Concurrent Cytomegalovirus Colitis and Bacteroidesfragilis Peritonitis in a Peritoneal Dialysis Patient. Perit Dial Int. 2015 Sep-Oct;35(5):587-8. doi: 10.3747/pdi.2014.00078.
  31. Chang SD, Lin YH, Liang CC, Chen TC. Effects of sacral nerve stimulation on postpartum urinary retention-related changes in rat bladder. Taiwan J Obstet Gynecol. 2015 Dec;54(6):671-7. doi: 10.1016/j.tjog.2015.10.001.
  32. Huang SC, Chuang HC, Chen TD, Chi CL, Ng KF, Yeh TS, Chen TC. Alterations of the mTOR pathway in hepatic angiomyolipoma with emphasis on the epithelioid variant and loss of heterogeneity of TSC1/TSC2. Histopathology. 2015 Apr;66(5):695-705. doi: 10.1111/his.12551.
  33. Huang SF, Kuo IM, Lee CW, Pan KT, Chen TC, Lin CJ, Hwang TL, Yu MC. Comparison study of gastrinomas between gastric and non-gastric origins. World J SurgOncol. 2015 Jun 16;13:202. doi: 10.1186/s12957-015-0614-6
  34. Tai HC, Chuang IC, Chen TC, Li CF, Huang SC, Kao YC, Lin PC, Tsai JW, Lan J, Yu SC, Yen SL, Jung SM, Liao KC, Fang FM, Huang HY. NAB2-STAT6 fusion types account for clinicopathological variations in solitary fibrous tumors. Mod Pathol. 2015 Oct;28(10):1324-35. doi: 10.1038/modpathol.2015.90.
  35. Lin JD, Hsueh C, Chao TC.Long-Term Follow-Up of the Therapeutic Outcomes for Papillary Thyroid Carcinoma With Distant Metastasis. Medicine (Baltimore). 2015 Jul;94(26):e1063. doi: 10.1097/MD.0000000000001063
  36. Liao CT, Fan KH, Kang CJ, Lin CY, Chang JT, Tsang NM, Huang BS, Chao YK, Lee LY, Hsueh C, Wang HM, Liau CT, Hsu CL, Hsieh CH, Ng SH, Lin CH, Tsao CK, Fang TJ, Huang SF, Chang KP, Yen TC. Clinical Outcomes of Patients with Resected Oral Cavity Cancer and Simultaneous Second Primary Malignancies. PLoS One. 2015 Sep 3;10(9):e0136918. doi: 10.1371/journal.pone.0136918.
  37. Liu FH, Kuo SF, Hsueh C, Chao TC, Lin JD. Postoperative recurrence of papillary thyroid carcinoma with lymph node metastasis. J SurgOncol. 2015 Aug;112(2):149-54. doi: 10.1002/jso.23967.
  38. Chuang WY, Chang H, Shih LY, Wang PN, Chang YS, Lin TL, Hung YS, Yeh CJ, Ueng SH, Tang TC, Kuo MC, Dunn P, Wu JH, Kao HW, Ou CW, Wan YL, Hsueh C. CD5 positivity is an independent adverse prognostic factor in elderly patients with diffuse large B cell lymphoma. Virchows Arch. 2015 Nov;467(5):571-82. doi: 10.1007/s00428-015-1845-1.
  39. Chuang WY, Chang YS, Chao YK, Yeh CJ, Liu YH, Tseng CK, Chang HK, Wan YL, Hsueh C. High sex determining region Y-box 2 (SOX2) expression correlates with absence of nodal metastasis in esophageal squamous cell carcinoma. Int J ClinExpPathol. 2015 Aug 1;8(8):9248-55.
  40. Lee CW, Chang KP, Chen YY, Liang Y, Hsueh C, Yu JS, Chang YS, Yu CJ. Overexpressed tryptophanyl-tRNAsynthetase, an angiostatic protein, enhances oral cancer cell invasiveness. Oncotarget. 2015 Sep 8;6(26):21979-92.
  41. Lai CY, Chao TC, Lin JD, Hsueh C. Sclerosingmucoepidermoid carcinoma with eosinophilia of thyroid gland in a male patient: a case report and literature review. Int J ClinExpPathol. 2015 May 1;8(5):5947-51. eCollection 2015.
  42. Yang W, Lai JY, Chao HC, Hsueh C. Gallbladder teratoma and a review of the literature. PediatrNeonatol. 2015 Apr;56(2):134-5. doi: 10.1016/j.pedneo.2014.06.008.
  43. Lee LA, Huang CG, Tsao KC, Liao CT, Kang CJ, Chang KP, Huang SF, Chen IH, Fang TJ, Li HY, Yang SL, Lee LY, Hsueh C, Lin CY, Fan KH, Chang TC, Wang HM, Ng SH, Yen TC.Human Papillomavirus Infections are Common and Predict Mortality in a Retrospective Cohort Study of Taiwanese Patients With Oral Cavity Cancer. Medicine (Baltimore). 2015 Nov;94(47):e2069. doi: 10.1097/MD.0000000000002069.
  44. Chuang WY, Chang YS, Chao YK, Yeh CJ, Ueng SH, Chang CY, Liu YH, Tseng CK, Chang HK, Wan YL, Hsueh C. Phosphorylated mTOR expression correlates with podoplanin expression and high tumor grade in esophageal squamous cell carcinoma. Int J ClinExpPathol. 2015 Oct 1;8(10):12757-65. eCollection 2015.
  45. Hsia SM, Yu CC, Shih YH, Yuanchien Chen M, Wang TH, Huang YT, Shieh TM.Isoliquiritigenin as a cause of DNA damage and inhibitor of ataxia-telangiectasia mutated expression leading to G2/M phase arrest and apoptosis in oral squamous cell carcinoma. Head Neck. 2015 Jan 10. doi: 10.1002/hed.24001.
  46. Yeh CT, Ho JY, Ng KF, Chen TC. OncomiR miR-96 and miR-182 promote cell proliferation and invasion through targeting ephrinA5 in hepatocellular carcinoma. Wang TH, MolCarcinog. 2015 Feb 8. doi: 10.1002/mc.22286.
  47. Shih, Y. H., Chang, K. W., Yu, C. C., Kao, M. C., Chen, M. Y., Wang, T. H.,Shieh, T. M. Hinokitiol suppressed pan-histone expression and cell growth in oral squamous cell carcinoma cells. J. Funct. Food. 2015. 15:452-463.
  48. Hu FW, Lee SS, Yang LC, Tsai CH, Wang TH, Chou MY, Yu CC. Knockdown of S100A4 impairs arecoline-induced invasiveness of oral squamous cell carcinomas. Oral Oncol. 2015 Jul;51(7):690-7. doi: 10.1016/j.oraloncology.2015.04.003. Epub 2015 Apr 23.
  49. Wang TH, Lin YS, Chen Y, Yeh CT, Huang YL, Hsieh TH, Shieh TM, Hsueh C, Chen TC. Long non-coding RNA AOC4P suppresses hepatocellular carcinoma metastasis by enhancing vimentin degradation and inhibiting epithelial-mesenchymal transition. Oncotarget. 2015 Sep 15;6(27):23342-57.
  50. Wang TH, Chen TC, Teng X, Liang KH, Yeh CT. Automated biphasic morphological assessment of hepatitis B-related liver fibrosis using second harmonic generation microscopy. Sci Rep. 2015 Aug 11;5:12962. doi: 10.1038/srep12962.
  51. Wang CJ, Chen TC, Lin JH, Huang PR, Tsai HJ, Chen CS. One-step preparation of hydrophilic carbon nanofiber containing magnetic Ni nanoparticles materials and their application in drug delivery. J Colloid Interface Sci. 2015 Feb 15;440:179-88. doi: 10.1016/j.jcis.2014.10.073. Epub 2014 Nov 8.
  52. Huang SC, Chuang HC, Chen TD, Chi CL, Ng KF, Yeh TS, Chen TC. Alterations of the mTOR pathway in hepatic angiomyolipoma with emphasis on the epithelioid variant and loss of heterogeneity of TSC1/TSC2. Histopathology 2015 DOI: 10.1111/his.12551
  53. Hsieh CY, Chang MY, Chen KH, Jenq CC, Li YJ, Chen TC, Yang CW, Chen YM. Concurrent Cytomegalovirus Colitis and Bacteroidesfragilis Peritonitis in a Peritoneal Dialysis Patient. Perit Dial Int. 2015 Sep-Oct;35(5):587-8. doi: 10.3747/pdi.2014.00078.
  54. Yang W, Lai JY, Chao HC, Hsueh C. Gallbladder teratoma and a review of the literature. PediatrNeonatol. 2015 Apr;56(2):134-5. doi: 10.1016/j.pedneo.2014.06.008.
  55. Huang SC, Ng KF, Lee SE, Chen KH, Yeh TS, Chen TC. HER2 testing in paired biopsy and excision specimens of gastric cancer: the reliability of the scoring system and the clinicopathological factors relevant to discordance. Gastric Cancer. 2014 Dec 17. DOI 10.1007/s10120-014-0453-0
  56. Wang CJ, Chen TC, Lin JH, Huang PR, Tsai HJ, Chen CS. One-step preparation of hydrophilic carbon nanofiber containing magnetic Ni nanoparticles materials and their application in drug delivery. J Colloid Interface Sci. 2015 Feb 15;440:179-88. doi: 10.1016/j.jcis.2014.10.073. Epub 2014 Nov 8.
  57. Hung TH, Hsu SC, Cheng CY, Choo KB, Tseng CP, Chen TC, Lan YW, Huang TT, Lai HC, Chen CM, Chong KY. Wnt5A regulates ABCB1 expression in multidrug-resistant cancer cells through activation of the non-canonical PKA/β-catenin pathway. Oncotarget. 2014 Dec 15;5(23):12273-90.
  58. Cheng CT, Tsai CY, Yeh CN, Chiang KC, Chen YY, Wang SY, Chen TW, Tseng JH, Jung SM, Chen TC, Yeh TS. Clinical significance of pathological complete response in patients with metastatic gastrointestinal stromal tumors after imatinibmesylate treatment--lessons learned. Anticancer Res. 2014 Nov;34(11):6617-25.
  59. Hsiao CC, Wang WC, Kuo WL, Chen HY, Chen TC, Hamann J, Lin HH. CD97 inhibits cell migration in human fibrosarcoma cells by modulating TIMP-2/MT1- MMP/MMP-2 activity--role of GPS autoproteolysis and functional cooperation between the N- and C-terminal fragments. FEBS J. 2014 Nov;281(21):4878-91. doi: 10.1111/febs.13027. Epub 2014 Sep 22.
  60. Huang CG, Lee LA, Tsao KC, Liao CT, Yang LY, Kang CJ, Chang KP, Huang SF, Chen IH, Yang SL, Lee LY, Hsueh C, Chen TC, Lin CY, Fan KH, Chang TC, Wang HM, Ng SH, Yen TC. Human papillomavirus 16/18 E7 viral loads predict distant metastasis in oral cavity squamous cell carcinoma. J ClinVirol. 2014 Oct;61(2):230-6. doi: 10.1016/j.jcv.2014.07.007. Epub 2014 Jul 22.
  61. Huang SC, Ng KF, Chen KH, Hsu JT, Liu KH, Yeh TS, Chen TC. Prognostic factors in Epstein-Barr virus-associated stage I-III gastric carcinoma: implications for a unique type of carcinogenesis. Oncol Rep. 2014 Aug;32(2):530-8. doi: 10.3892/or.2014.3234. Epub 2014 Jun 5.
  62. LE PH, Huang SC, Lim SN, Chou CH, Yeh TS, Chen TC, Yen TH, Su MY, Chiu CT, Yeh CT, Lin WR. Complex IV subunit 1 defect predicts postoperative survival in hepatocellular carcinoma. OncolLett. 2014 May;7(5):1430-1438. Epub 2014 Mar 11.
  63. Chen HH, Lin MW, Tien WT, Lai CP, Weng KY, Ko CH, Lin CC, Chen JC, Tiao KT, Chen TC, Chen SC, Yeh TS, Cheng CF. High-purity separation of cancer cells by optically induced dielectrophoresis. J Biomed Opt. 2014 Apr;19(4):045002. doi: 10.1117/1.JBO.19.4.045002.
  64. Chen KH, Hsu SC, Chen HY, Ng KF, Chen TC. Utility of fluorescence in situ hybridization for ploidy and p57 immunostaining in discriminating hydatidiform moles. BiochemBiophys Res Commun. 2014 Apr 4;446(2):555-60. doi: 10.1016/j.bbrc.2014.03.003. Epub 2014 Mar 12.
  65. Hung YS, Chou WC, Chen TD, Chen TC, Wang PN, Chang H, Hsu HC, Shen WC, Cheng WH, Chen JS. Prognostic factors in adult patients with solid cancers and bone marrow metastases. Asian Pac J Cancer Prev. 2014;15(1):61-7.
  66. Liang CC, Lin YH, Chen TC, Chang SD. How antepartum and postpartum acute urinary retention affects the function and structure of the rat bladder. IntUrogynecol J. 2014 Aug;25(8):1105-13. doi: 10.1007/s00192-013-2320-7. Epub 2014 Feb 11.
  67. Yeh CT, Huang YH, Liang KH, Chang ML, Hsu CW, Chen YC, Chen TC, Yeh TS, Lee WC. Segregation of signaling proteins as prognostic predictors for local recurrence and distant metastasis in hepatocellular carcinoma. Int J Oncol. 2014 Feb;44(2):491-504. doi: 10.3892/ijo.2013.2198. Epub 2013 Nov 29.
  68. Yeh TS1, Wang F, Chen TC, Yeh CN, Yu MC, Jan YY, Chen MF. Expression profile of microRNA-200 family in hepatocellular carcinoma with bile duct tumor thrombus. Ann Surg. 2014 Feb;259(2):346-54. doi: 10.1097/SLA.0000000000000223.
  69. Chou WC, Chen JS, Hung YS, Hsu JT, Chen TC, Sun CF, Lu CH, Hwang TL. Plasma chromogranin A levels predict survival and tumor response in patients with advanced gastroenteropancreatic neuroendocrine tumors. Anticancer Res. 2014 Oct;34(10):5661-9.
  70. Yeh CT, Huang YH, Liang KH, Chang ML, Hsu CW, Chen YC, Chen TC, Yeh TS, Lee WC. Segregation of signaling proteins as prognostic predictors for local recurrence and distant metastasis in hepatocellular carcinoma. Int J Oncol. 2014 Feb;44(2):491-504. doi: 10.3892/ijo.2013.2198. Epub 2013 Nov 29.
  71. Dutta A, Miaw SC, Yu JS, Chen TC, Lin CY, Lin YC, Chang CS, He YC, Chuang SH, Yen MI, Huang CT. Altered T-bet dominance in IFN-g-decoupled CD4+ T Cells with attenuated cytokine storm and preserved memory in influenza. The Journal of Immunology 2013, 190:4205-4214. April
  72. Yeh CT, Liang KH, Chang ML, Hsu CW, Chen YC, Lin CL, Lin WR, Lai MW. Phenotypic and Genotypic Shifts in Hepatitis B Virus in Treatment-Naive Patients, Taiwan, 2008-2012. Emerg Infect Dis. 2017 May;23(5):820-821. doi: 10.3201/eid2305.161894.
  73. Chen TC, Jan YY, Yeh TS. K-ras mutation is strongly associated with perineural invasion and represents an independent prognostic factor of intrahepatic cholangiocarcinoma after hepatectomy. Ann SurgOncol 2012 Jul;19Suppl 3:S675-81.
  74. Chao A, Chen TC, Hsueh C, Huang CC, Yang JE, Hsueh S, Huang HJ, Lin CT, Tang YH, Liou JD, Chang CJ, Chou HH, Lai CH. Human Papillomavirus in vaginal intraepithelial neoplasia. Int J cancer Int J Cancer. 2012 Aug 1; 131(3):E259-68. (Co-first author)
  75. Wang TH, Chang JL, HO JY, Wu HC, Chen TC*. EphrinA5 suppresses colon cancer development by negatively regulating EGFR stability. FEBS j 2012; 279(2):251-63. (Corresponding author).
  76. Chang LY, Lin YC, Mahalingam J, Huang CT, Chen TW, Kang CW, Peng HM, Chu YY, Chiang JM, Dutta A, Day YJ, Chen TC, Yeh CT, Lin CY. Tumor-derived chemokine CCL5 enhances TGF-ss mediated killing of CD8+ T cells in colon cancer by T regulatory cells. Cancer Res. 2012 Mar 1;72(5):1092-102.
  77. Wu TH, Yu MC, Chen TC, Lee CF, Chan KM, Wu TJ, Chou HS, Lee WC, Chen MF. Encapsulation is a significant prognostic factor for better outcome in large hepatocellular carcinoma. J SurgOncol. 2012 Jan;105(1):85-90.
  78. Huang SC, Chang HC, Yeh TS, Ng KF, Chen TC. Hepatoidmicrocarcinoma of the pancreas: A case report and review of the literature. Chang Gung Medical Journal 2012; 35:285-91. (Corresponding author).
  79. Chou WC, Hung YS, Hsu JT, Chen JS, Lu CH, Hwang TL, Rau KM, Yeh KY, Chen TC, Sun CF. Chromogranin A Is a Reliable Biomarker for Gastroenteropancreatic Neuroendocrine Tumors in an Asian Population of Patients. Neuroendocrinology. 2012 Feb 14
  80. Wu TJ, Chen TC, Wang F, Chan KM, Soong RS, Chou HS, Lee WC, Yeh CT. Large fragment pre-s deletion and high viral load independently predict hepatitis B relapse after liver transplantation.PLoS One. 2012;7(2):e32189. Epub 2012 Feb 21
  81. Chang JWC, Wei NC, Su HJ, Huang JL, Chen TC, Wu YC, Yu CT, Hou MM, Hsieh CH, Hsieh JJ, Wu CE, Cheng HY, Hsu T, Wang TH. Comparison of genomic signatures of non-small cell lung cancer recurrence between two microarray platforms. Anticancer Res 2012; 32(4): 1259-65.
  82. Huang YH, Lin KH, Chen HC, Chang ML, Hsu CW, Lai MW, Chen TC, Lee WC, Tseng YH, Yeh CT. Identification of Postoperative Prognostic MicroRNA Predictors in Hepatocellular Carcinoma. PLoS One 2012; 7(5):e37188.
  83. Chang LY, Lin YC, Kang CW, Hsu CY, Chu YY, Huang CT, Day YJ, Chen TC, Yeh CT, Lin CY. The Indispensable Role of CCR5 for In Vivo Suppressor Function of Tumor-Derived CD103+ Effector/Memory Regulatory T Cells. J Immunol 2012 Jul 15; 189(2):567-74.
  84. Chen CS, Chen TC, Chen CC, Lai YT, You JH, Chou TM, Chen CH, Lee JF. Effect of Ti3+ on TiO2-supported Cu catalysis used for CO oxidation. Langmuir 2012 Jul 3; 28(26): 9996-10006.
  85. Lee LA, Huang CG, Liao CT, Lee LY, Hsueh C, Chen TC, Lin CY, Fan KH, Wang HM, Huang SF, Chen IH, Kang CJ, Ng SH, Yang SL, Tsao KC, Chang YL, Yen TC. Human papillomavirus-16 infection in advanced oral cavity cancer patients is related to an increased risk of distant metastases and poor survival. PLoS One. 2012; 7(7): e40767.
  86. Wang TH, Ng KF, Yeh TS, Wang YL, Liang KH, Yeh CT, Chen TC*. Peritumoral small ephrinA5 isoform level predicts the postoperative survival in hepatocellular carcinoma. PLoS One. 2012; 7(7): e41749. (Corresponding author)
  87. Yeh CN, Yeh TS, Chen TC, Jan YY, Chen MF. Gross pathological classification of peripheral cholangiocarcinoma determines the efficacy of hepatectomy.JGastroenterol. 2012 Sep 25.
  88. Lai CH, Chou HH, Chang CJ, Wang CC, Hsueh S, Huang YT, Chen YR, Chang HP, Chang SC, Lin CT, Chao A, Qiu JT, Huang KG, Chen TC, Jao MS, Chen MY, Liou JD, Huang CC, Chang TC, Patsner B. Clinical implications of human papillomavirus genotype in cervical adeno-adenosquamous carcinoma. Euro J Cancer Eur J Cancer. 2012 Sep 29
  89. Lo SJ, Fan LC, Tsai YF, Lin KY, Huang HL, Wang TH, Liu H, Chen TC, Huang SF, Chang CJ, Lin YJ, Yung BY, Hsieh SY. A novel interaction of nucleophosmin with BCL2-Associated X protein regulating death evasion and drug sensitivity in human hepatoma cells. Hepatology. 2012 Dec 19. doi: 10.1002/hep.26209.
  90. Yeh TS, Chen TC, Yeh CN, et al. Expression profile of microRNA-200 family in hepatocellular carcinoma with bile duct tumor thrombus. Ann Surg 2012 (in press) IF=7.492 R/C=1/199)
  91. Chang YT, Wu CC, Shyr YM, Chen TC, Hwang TL, Yeh TS, Chang KP, Liu HP, Liu YL, Tsai MH, Chang YS, Yu JS. Secretome-Based Identification of ULBP2 as a Novel Serum Marker for Pancreatic Cancer Detection. PLoS One. 2011;6(5):e20029. Epub 2011 May 20.
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  95. Chou CC, Chang PC, Wen MS, Lee, HL, Chen TC, Yeh SJ, Wu D. Epicardial ablation of rotors supressesinducibility of acetylcholine-induced atrial fibrillation in left pulmonary vein-left atrium preparations in a beagle heart failure model. J Am CollCardiol. 2011 Jul 5;58(2):158-66.
  96. Sung KF, Chu YY, Liu NJ, Hung CF, Chen TC, Chen JS, Lin CH. Direct peroralcholangioscopy and pancreatoscopy for diagnosis of a pancreatobiliary fistula caused by an intraductal papillary mucinous neoplasm of the pancreas: a case report. Dig Endosc. 2011 Jul;23(3):247-50.
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  98. Peng CH, Liao CT, Peng SC, Chen YJ, Cheng AJ, Juang JL, Tsai CY, Chen TC, Chuang YJ, Tang CY, Hsieh WP, Yen TC. A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma. PLoS One. 2011;6(8):e23452. Epub 2011 Aug 11
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  102. Cheng CH, Lee CF, Wu TH, Chan KM, Chou HS, Wu TJ, Yu MC, Chen TC, Lee WC, Chen MF. Evaluation of the new AJCC staging system for resectable hepatocellular carcinoma. World J SurgOncol. 2011 Sep 30;9(1):114.
  103. Chao A, Jao MS, Huang CC, Huang HJ, Cheng HH, Yang JE, Hsueh S, Chen TC, QiuJT,Lin CT, Fu CJ, Chou HH,>Lai CH. Human papillomavirus genotype in cervical intraepithelial neoplasia grade 2 and 3 of Taiwanese women. Int J Cancer. 2011 Feb 1;128(3):653-9.
  104. Kuo WL, Yu MC, Lee JF, Tsai CN, Chen TC, Chen MF. ImatinibMesylate Improves Liver Regeneration and Attenuates Liver Fibrogenesis in CCL(4)-Treated Mice. J Gastrointest Surg. 2011 Nov 9. Hsu SC, Huang CK, Chen TC*. The importance of HER2 testing quality. BioMedicine 2011; Nov 4(4): 207-19. (Corresponding author)
  105. Hsu SC, Huang CK, Chen TC*. Clinical Audit of HER2 Testing. BioMedicine 2011; Nov 4(4): 220-3. (Corresponding author)
  106. Chang HC, Huang SC, Chen TC, Law MW, Chen SY, Lai JY. Y-shaped colonic duplication: report of a case and literature review. Chang Gung Med J 2011; 34(6 Suppl): 43-7.

 

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