Chang Gung Memorial Hospital Department of Orthopaedic Surgery Index

Chang Gung Memorial Hospital Lin-Kou Medical Center is the largest and the leading hospital in Taiwan. Each surgeon at spine section of Orthopaedic department has completed an extensive spine fellowship program and has years of outstanding training and experience in the diagnosis, surgical and non-surgical treatment of spine disorders including the neck (cervical spine), mid back (thoracic spine) and low back (lumbosacral spine) in adults as well as children. The specialists offer comprehensive care in all areas of spine problems on patients who suffer from spine trauma, degenerative disease (spinal stenosis, intervertebral disc herniation and spondylolisthesis), osteoporosis, deformity (scoliosis and kyphosis), infection, tumor and metastasis. Each year, the surgeons of spine team perform more than 3000 spine procedures from minimally invasive spine surgery to traditional procedures for the most challenging conditions of spine in this hospital. The type of treatment depends on the patient's degree of disease and a thorough physical examination and radiological examinations.

Wen-Jer Chen

Educational
background

National Taiwan University, College of Medicine

Position

Chairman of Department of Orthopaedic Surgery (2001 – 2011), Chang Gung Memorial Hospital/
Attending physician of Spine Section, Department of Orthopaedic Surgery/
Professor of Chang Gung University and Chang Gung Memorial Hospital

professional specialty

Low back pain and sciatica, Adjacent instability after spine fusion,
Degenerative lumbar scoliosis, Failed back surgery syndrome, Osteoporosis
Spine tumor. Spine infection

chenwenj@adm.cgmh.org.tw

Publications

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Chen, W.J., Wu, C.C., Lin, Y.H., and Shih, C.H.: Treatment of Deltoid Contracture in Adults by Distal Release of the Delboid. Clin Orthop Relat R, Vol. 378:136-142, 2000. (SCI)

Chen, W.J., Lai, P.L., Niu, C.C., Chen, L.H., Fu, T.S. and Wong, C.B.: Surgical Treatment of Adjacent Instability after Lumbar Spine Fusion. Spine, Vol. 26, No.22, pp.E519-E524, 2001. (SCI)

Chen, W.J., Wu, C.C., Jung, C.H., Chen, L.H., Niu, C.C. and Lai, P.L.: Combined Anterior and Posterior Surgeries in the Treatment of Spinal Tuberculous Spondylitis. Clin Orthop Relat R, Vol. 398:50-59, 2002. (SCI)

Chen,W.J., Tsai, T.T., Chen, L.H., Niu, C.C., Lai, P.L., Fu, T.S., Kevin McCarthy: The Fusion Rate of Calcium Sulfate with Local Autograft Bone Compared with autologous Iliac Bone Graft for Instrumented short-Segment Spinal fusion. Spine, Vol.30(20):2293-2297, Oct. 2005. (SCI)

Chen, W.J., Huang, J.W., Niu, C.C., Chen, L.H., Yuan, L.J., Lai, P.L., Yang, C.Y., Lin, S.S.: Use of Fluorescence Labeled Mesenchymal Stem Cells in Pluronic F127 and Porous Hydroxyapatite As a Bone Substitute for Posterolateral Spinal Fusion. Journal of OrthopaedicResearch, Vol. 27(12): 1631-1636.2009. (Corresponding author) (SCI )

Lih-Huei Chen

Educational
background

Medical school of China Medical University

Position

Chief, Department of Orthopaedic/
Attending physician of Spine Section, Department of Orthopaedic Surgery/ Professor of Chang Gung University and Chang Gung Memorial Hospital

professional specialty

Osteoporosis, Vertebroplasty, Intervertebral Disc Herniation, Spinal Stenosis、Spondylolisthesis、Spinal Deformity Correction, Spinal Infection, Spinal Fracture, Spine Tumor Surgery, Back Pain, Sciatica

lhchen2132@adm.cgmh.org.tw

Publications

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Chen, L.H.＊, Tai, C.L., Lai, P.L., Lee, D.M., Tsai, T.T., Fu, T.S., Niu, C.C., Chen, W.J.: Pullout strength for cannulated pedicle screws with bone cement augmentation in severely osteoporotic bone: Influences of radial hole and pilot hole tapping. Clinical Biomechanics 24:613-618, 2009.(SCI )

Chen, L.H. ＊, Fu, T.S., Kao, Y.H., Tsai, T.T., Lai, P.L., Niu, C.C., Chen, W.J.: Surgical treatment of infectious spondylitis in patients undergoing hemodialysis therapy. Eur Spine J, Vol.19: 2223-2228, 2010. (SCI)

Chen, L.H.＊, Hsieh, M.K., Liao, J.C., Lai, P.L., Niu, C.C., Fu, T.S., Tsai, T.T., Chen, W.J.: Repeated percutaneous vertebroplasty for refracture of cemented vertebrae. Archives of Orthopaedic and Trauma Surgery. 131: 927-933. 2011. (SCI)

Chen, L.H., Tai, C.L. ＊, Lee, D.M., Lai, P.L., Lee, Y.C., Niu, C.C., Chen, W.J.: Pullout strength of pedicle screws with cement augmentation in severs osteoporosis: A comparative study between cannulated screws with cement injection and solid screws with cement pre-filling. BMC Musculoskelet Disord. 12(1): 33-1~33-11. Feb. 1, 2011.(SCI)

Chen, L.H. ＊, Lai, P.L., Chen, W.J.: Current Status of Vertebroplasty for Osteoporotic Compression Fracture. Chang Gung Med J:Vol.34(4):352-359, Jul.-Aug. 2011.

Chen, L.H. ＊, Hsieh, M.K., Niu, C.C., Fu, T.S., Lai, P.L., Chen, W.J.: Percutaneous vertebroplasty for pathological vertebral compression fractures secondary to multiple myeloma. Arch Orthop Tramua Surg: Vol.132(6):759-764, 2012. (SCI )

Chi-Chien Niu

Educational
background

National Taiwan University, College of Medicine

Position

Chief of Spine Section, Department of Orthopaedic/
Attending physician of Spine Section, Department of Orthopaedic Surgery;
Associate Professor of Chang Gung University and Chang Gung Memorial Hospital

professional specialty

Surgery for Degenerative Spine Disease, Spine Infection, and Spine Neoplasm, Consultation for Cervical Spine Pathology, Minimal Invasive Spine Surgery(eg. Percutaneons endoscopic Laser-Aided Discectomy, Vertebroplasty for Osteoporotic Compression Fracture of Spine), Artificial Disc Replacement, Motion-Preservation Stabilizing Surgery of Spine, Research of Dise Cell Regeneration

niuchien@adm.cgmh.org.tw

Publications

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Niu, C.C. ＊, Chen, L.H., Lai, P.L., Fu, T.S., Chen, W.J.: Single Cylindrical Threaded Cage Used in Fusion for Recurrent Lumbar Disc herniation. J of Spinal Disorders & Techniques, Vol.18:Suppl.S65-72, Feb. 2005.(SCI；IF=1.365；Orthopedics 27/49)

Kao, F.C., Niu, C.C.＊, Chen, L.H., Lai, P.L. and Chen, W.J.: Maintenance of Interbody Space in One- and Two- Level Anterior Cervical Interbody Fusion – Comparison of the Effectiveness of Autograft, Allograft and Cage. Clinical of Orthopaedic and Related Research, Vol.430:108-116, 2005.(SCI；IF=1.893；Orthopedics 16/49) (Corresponding author)

Yang, S.C., Yu, S.W., Tu, Y.K., Niu, C.C.＊, Chen, L.H., Chen, W.J.:Open-door Laminoplasty with suture anchor fixation for cervical myelopathy in ossification of the posterior longitudinal ligament. J Spinal Disord Tech, Vol.20(7):492-498, Oct.2007.(SCI；IF=1.365；Orthopedics 27/49) (Corresponding author)

Niu, C.C., Yuan, L.J., Lin, S.S., Chen, L.H., Chen, W.J.: Mesenchymal Stem Cell and Nucleus Pulposus Cell CocultureModulates Cell Profile. Clin Orthop Relat Res, :Vol.467:3263-3272, Oct. 2009.(SCI )

Niu, C.C., Tsai, T.T., Fu, T.S., Lai, P.L., Chen, L.H., Chen, W.J.:A Comparison of Posterolateral Lumbar Fusion Comparing Autograft, Autogenous Laminectomy Bone with Bone Marrow Aspirate, and Calcium Sulphate with Bone Marrow Aspirate- A Prospective Randomized Study. Spine, Vol. 34(25): 2715-2719.2009.(SCI )

Tsai-Sheng Fu

Educational
background

Medical school of Taipei Medical University

Position

Chief, Department of Orthopaedic in Keelung Chang Gung Memorial Hospital/
Associate Professor;Attending physician of Spine Section, Department of Orthopaedic Surgery;Chang Gung Memorial Hospital

professional specialty

Minimally Invasive Spine Surgery, Endoscopic Spine Surgery, Computer-aid Image Guide Spine Surgery ; 2.Clinical Disease: Intervertebral Disc Herniation, Spondylolisthesis, Spine Deformity(Scoliosis and Kyphosis), Spinal Metastatic Tumor、Spinal Infection, Vertebral Fracture, Osteoporosis, Sciatica, Spinal Stenotic Syndrome ; 3.Research: Research of Intervertebral Disc Regeneration and Mesenchymal Stem Cell for spinal fusion

fts111@adm.cgmh.org.tw

Publications

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Fu TS, Steve WN Ueng, Tsai TT, Chen LH, Lin SS, Chen WJ. Effect of hyperbaric oxygen on mesenchymal stem cells for lumbar fusion in vivo. BMC Musculoskeletal Disorders (Accepted, In press). (SCI)

Fu TS, Yang, S.C., Tsai, T.T., Chen, L.H., Lai, P.L., Niu, C.C. , Chen, W.J. Percutaneous endoscopic debridement and drainage in immunocompromised patients with complicated infectious spondylitis. Minimally Invasive Therapy and Allied Technologies Vol.19: 42-47.2010 (SCI)

Fu TS, Chen WJ, Chen LH, Lin SS, Liu SJ, Steve WN Ueng. Enhancement of Posterolateral Lumbar Spine Fusion using Low Dose rhBMP-2 and Cultured Marrow Stromal Cells. J Orthop Res. 2009 Mar.;27:380-384. (SCI) (93-2314-B-182A-036)

Yang SC, Fu TS, Chen LH, Chen WJ, Tu YK. Identifying Pathogens of Spondylodiscitis: Percutaneous Endoscopy or CT-guided Biopsy. Clin Orthop Relat Res. 2008 Dec;466(12):3086-92. (Corresponding author) (SCI)

Fu TS, Lai PL, Tsai TT, Niu CC, Chen LH, Chen WJ. Long-term results of disc excision for recurrent lumbar disc herniation with or without posterolateral fusion. Spine 2005 Dec 15:30(24):2830-2834. (SCI)

TEXTBOOK CHAPTERS

E Hoang Le, M.D., Tsai-Sheng Fu, M.D.,Tae-Ahn Jahng, M.D., Ph.D., Daniel H. Kim, M.D. "Current Minimally Invasive Surgical Techniques for the Lumbar Spine" Emerging Spine Surgery Technologies: Evidence and Framework for Evaluating New Technology. Page273-291; Edited by Terry P. Corbin, B.S.B.M.E, Patrick J. Connolly, M.D., Hansen A.Yuan, M.D., Qi-Bin Bao, Ph.D., Scott D. Boden, M.D. Quality Medical Publishing (2005)

Fu TS, Wong CB, Chen WJ: "Spinal Tuberculosis" VI-Inflammatory and Infectious Diseases of the Pediatric Spine- 32, P390-395；Edited by Daniel H. Kim., Randal R. Betz., Stephen L. Huhn., Peter O. Newton, Surgery of the Pediatric Spine, Thieme.(2008)

Po-Liang Lai

Educational
background

National Taiwan University School of Medicine

Position

Attending Physician and Associated Professor of
Department of Orthopaedic Surgery, Spine Section,
Chang Gung Memorial Hospital

professional specialty

Scoliosis Surgery, Minimally Invasive Spine Surgery, Biomaterial

hardbone@adm.cgmh.org.tw

Publications

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Lai PL, Chen LH, Niu CC, Chen WJ. The effect of postoperative lumbar sagittal alignment on the development of adjacent instability. Journal of Spinal Disorders and Techniques 17(5):353-357, Oct 2004. (SCI)

Lai PL, Chen LH, Niu CC, Fu TS, Chen WJ. Relation between laminectomy and development of adjacent instability after lumbar fusion with pedicle fixation. Spine29(22):2527-2532, Nov 15, 2004. (SCI)

Chen LH, Lai PL(Corresponding), Chen WJ. Unipedicle percutaneous vertebroplasty for spinal intraosseous vacuum cleft. Clinical Orthopaedics & Related Research(435):148-53, 2005 Jun. (SCI)

Lai, P.L., Leu, H.S., Niu, C.C., Chen, W.J., Chen, L.H.: Pyogenic Spondylitis Presenting with Skip Lesions. Chang Gung Med J, Vol.28,No.9:651-656, Sep.2005.

Tai, C.L., Hsieh, P.H., Chen, W.P., Chen, L.H., Chen, W.J., Lai, P.L. (corresponding). Biomechanical comparison of lumbar spine instability between laminectomy and bilateral laminotomy for spinal stenosis syndrome- an experimental study in porcine model. BMC Musculoskeletal Disorders 9:84:1~9, June 2008. (SCI)

TEXTBOOK CHAPTERS

Lai, P.L., Chen, W.J.: "Nonsurgical Treatment of Spinal Deformities" Chapter 49, P635-643；Daniel H. Kim., Randal R. Betz., Stephen L. Huhn., Peter O. Newton, Surgery of the Pediatric Spine, Thieme.(2008)

Tsung-Ting Tsai

Educational
background

Medical school of China Medical University

Position

Attending Physician and Associated Professor of
Department of Orthopaedic Surgery, Spine Section,
Chang Gung Memorial Hospital

professional specialty

Spine Degeneration, Osteoporosis, Spine Fracture, Spine Infection, Minimally Invasive Spine Surgery, Inter-Vertebral Disc Study, Notochordal Cell and Mesenchymal Stem Cell Study

tsai1129@gmail.com

Publications

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1. Tsai TT, Ho NY, Fang HC, Lai PL, Niu CC, Chen LH, Chen WJ, Pang JH*. Increased sulfatase 1 gene expression in degenerative intervertebral disc cells. J Orthop Res, 中華民國骨科醫學會103年度優秀論文比賽基礎類別第二名

2. Tsai TT, Ho NY, Lin YT, Lai PL, Fu TS, Niu CC, Chen LH, Chen WJ, Pang JH*. Advanced glycation end products in degenerative nucleus pulposus with diabetes. J Orthop Res, 2014 Feb;32(2) :238-244.林口長庚醫院SCI優秀論文

3. Tsai TT, Shen SW, Cheng CM, Chen CF*. Paper-based tuberculosis diagnostic devices with colorimetric gold nanoparticles. Sci. Technol. Adv. Mater. 2013;14:044404. 中華民國骨科醫學會102年度優秀論文比賽基礎類別第三名

4. Tsai TT, Lai PL, Liao JC, Fu TS, Niu CC, Chen LH, Lee MS, Chen WJ, Fang HC, Ho NY, Pang JH*. Increased periostin gene expression in degenerative intervertebral disc cells. Spine J, 2013 Mar;13(3):289-298.林口長庚醫院SCI優秀論文

5. Tsai TT, Guttapalli A, Agrawal A, Albert TJ, Shapiro IM, Risbud MV*. MEK/ERK Signaling Controls Osmoregulation of Nucleus Pulposus Cells of the Intervertebral Disc by Transactivation of TonEBP/OREBP. J Bone Miner Res, 2007 Jul;22(7):965-74.

Chia-Wei Yu

Educational
background

Medical school of Taipei Medical University

Position

Attending physician of Spine Section, Department of Orthopaedic Surgery

professional specialty

Spine osteoporotic-related disease; Lumbar spine degenerative disease; Thoraco-lumbar spine traumatic fracture; Cervical spine degenerative disease; Spinal bone and neurologic tumor; Spinal infective disease; Newly non-fusion techniques spinal surgery; Bone substitute and spinal cages

vincentyu88@adm.cgmh.org.tw

Publications

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Aseptic Nonunion of a Femoral Shaft Treaced by Exchange Nailing. Chang Gung Medical Journal.

Wen-Chien Chen

Educational
background

Medical school of Taipei Medical University

Position

Attending physician of Spine Section, Department of Orthopaedic Surgery

professional specialty

Herniation of intervertebral disc; sciatica; lower back pain; correction and treatment of spine deformities including: scoliosis, spinal slippage, and kyphosis; minimal invasive spine surgery including: vertebroplasty, percutaneous endoscopic disectomy, nerve block; transpedicle screw instrumentation of spine including traditional fixation type, dynamic stabilization type, and percutaneous minimal invasive type; excision of spine tumor; osteoporosis consultation and treatment; treatment of spine fractures

surgeonmonster@adm.cgmh.org.tw

Publications

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1. Yu, Y.H., Chen, W.J., Chen, L.H., Chen, W.C.: Ischemic Orbital Compartment Syndrome After Posterior Spinal Surgery. Spine 33(16):E569-E572, 2008.(SCI)

2. Chen, W.C., Chen, W.J., Niu, C.C.: Percutaneous Vertebroplasty Using Calcium Sulfate Cement for Osteoporotic Vetebral Compression Fractures with Vacuum Cleft. J Orthop Surg Taiwan 25:156-164, 2008

3. Chen, C.C., Chen, W.J., Chen, L.H., Chen, W.C., Lai, P.L.: Management of complications after posterior lumbar interbody fusion with cages and posterior instrumentation: report of seven cases. J. Orthop Surg Taiwan, Vol. 26(3): 137-143, Sep. 2009.

Ming-Kai Hsieh

Educational
background

Medical school of China Medical University

Position

Attending physician of Spine Section, Department of Orthopaedic Surgery

professional specialty

spinal fracture; spinal tumor; herniated intervertebral disc; sciatica; neck pain; scoliosis and kyphosis; minimal invasive spinal surgery; osteoporosis

stock-best@yahoo.com.tw

Publications

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Ming-Kai Hsieh, Alvin Chao-Yu Chen, Chun-Ying Cheng, Ying-Chao Chou, Yi-Sheng Chan, Kuo-Yau Hsu Repositioning Osteotomy for Intra-Articular Malunion of Distal Radius With Radiocarpal and/or Distal Radioulnar Joint Subluxation ,J Trauma. 2010;69: 418–422(SCI)

Ming-Kai Hsieh, Chen-Nen Chang, Mei-Chun Hsiao, Wen-Jer Chen, Lih-Huei Chen Conversion Paralysis After Surgery for Lumbar Disc Herniation ,Spine 2010;35:E308–E310(SCI)

Ming-Kai Hsieh, Lih-Huei Chen, Chi-Chien Niu, Tsai-Sheng Fu,Po-Liang Lai, Wen-Jer Chen Postoperative anterior spondylodiscitis after posterior pedicle screw instrumentation, Spine J 2011;11:24-29(SCI)

Lih-Huei Chen,Ming-Kai Hsieh,Jen-Chung Liao,Po-Liang Lai,Chi-Chien Niu ,Tsai-Sheng Fu,Tsung-Ting Tsai ,Wen-Jer Chen Repeated percutaneous vertebroplasty for refracture of cemented vertebrae, Arch Orthop Trauma Surg(In press) (SCI)

I.Services of Spine Center：

1. Degenerative lumbar spine disease（Herniation of Intervertebral Disc(HIVD)、
Spinal stenosis、Spondylolisthesis、Degenerative lumbar scoliosis）

2. Cervical spine（Stenosis or instability）

3. Spine deformityScoliosis、Kyphosis）

4. Spine infection

5. Spine tumor（Primary tumor and metastasis）

6. Spine trauma（Fracture or Dislocation）

7. Osteoporotic vertebral compression fracture

8. Minimally Invasive Spine Surgery（PELD、MED、Vertebroplasty、Spine instrumentation）

9. Computer assisted spine surgery

10. Dynamic Stabilization of Spine

11. Artificial disc replacement

12. Osteoporosis, diagnosis and treatment

II.Our Mission & Vision：

Provide the highest level of clinical services for spine

disorders and enhance the quality of life.
Provide the latest information and training program for

spine specialists.
Identify the mechanisms of spine diseases and to

discover and develop effective approaches for prevention,

diagnosis and treatment of these disorders.
Utilize resources and expand collaboration within our

department and university to maximize effectiveness and

efficiency of clinical and basic research.
Perform basic research to define the mechanisms of

spine disease at the genetic, cellular and structural level

and apply the results to clinical treatments.