PROFESSIONAL POST

MD, Professor

Education

1976-1983       Medical School  Taipei Medical College

                                                Taipei, Taiwan

1982-1983       Internship    Veteran General Hospital    

                                                Taipei, Taiwan

ACADEMIC AND PROFESSIONAL ACTIVITIES

1976-1983 Taipei Medical University

1985-1988         Resident, Internal Medicine, Chang Gung Memorial Hospital, LinKou, Taiwan

1988-1990         Clinical Fellow, Division of Nephrology, Chang Gung Memorial Hospital

1990-1999         Attending Physician, Division of Nephrology, Chang Gung Memorial Hospital

1990-1994         Visiting Associate, Renal Cell Biology Section, NIDDK, National Institutes of Health,      USA    

1999-2003         Chief, Division of Artificial Kidney, Department of Nephrology, Chang Gung Memorial Hospital

1999-2001 Deputy Secretary-General, Taiwan Society of Nephrology,  

2003-2010         Director, Department of Nephrology, Chang Gung Memorial Hospital, Taiwan

2003-2009         Vice Chairman, Department of Internal Medicine, Chang Gung Memorial Hospital, LinKou, Taiwan

2004~      Director, Kidney Research Center, Chang Gung, Memorial Hospital, LinKou, Taiwan

2005-2009         Chairman, Department of Medical Research, Chang, Gung Memorial Hospital, LinKou, Taiwan

2005-2007 Chairman, Nephrology Board Committee, Taiwan Society of Nephrology

2007~         Executive Councilor, Taiwan Society of Nephrology

2007-2012  Vice Chairman, Research & Development Committee, Chang Gung Medical Organization, Taiwan

2009-2011 Chairman, Department of Internal Medicine, Chang Gung Memorial Hospital, LinKou, Taiwan

2009~         Council Member, International Society of Nephrology

2009~         Nexus Committee Core Member, International Society of Nephrology

2009~         Member, Global Outreach East Asia Committee, International Society of Nephrology

2010~         Chairman, International Affair Committee, Taiwan Society of Nephrology

2011~         Dean, College of Medicine, Chang Gung University

EDITORIAL BOARD

2007~2012   Kidney International (Official Journal, International Society of Nephrology)

2007~2010  Acta Nephrologica (Official Journal, Taiwan Society of Nephrology)

2010~  Chang Gung Medical Jounral

2011~ Associate Editor, Acta Nephrologica

2011~ Subject Editor, Nephrology (Official Journal, Asian Pacific Society of Nephrology)

MAJOR BIBLIOGRAPHY (limited 10 papers)

1.          Chou LF, Chen YT, Lu CW, Ko YC, Tang CY, Pan MJ, Tian YC, Chiu CH, Hung CC, Yang CW*.Sequence of leptospira santarosai serovar shermani genome and prediction of virulence-associated genes. GENE, 2012,511(2):364-70.

2.          Yang HY, Yen TH, Lin CY, Chen YC, Pan MJ, Lee CH, Yu CC, Wu MS, Wu SS, Weng CH, Chen KH, Hung CC, Yang CW*Early identification of leptospirosis as an ignored cause of multiple organ dysfunction syndrome. SHOCK, 2012. 38(1):24-9.

3.          Tian YC, Hung CC, Li YJ, Chen YC, Chang MY, Yen TH, Hsu HH, Wu MS, Phillips A, Yang CW* Leptospira santorosai serovar shermani detergent extract induced an increases in fibronectin production through a toll-like receptor2-mediated pathway.. Infect Immun., 2011,79(3):1134-42.

4.          Hsu SH, Lo YY, Tung JY, Ko YC, Sun YJ, Hung CC, Yang CW, Tseng FG, Fu CC, Pan RL. Leptospiral outer membrane lipoprotein lipl32 binding on toll-like receptor 2 of renal cells as determined with an atomic force microscope . Biochemistry, 2010, 6;49(26):5408-17

5.          Tung JY, Yang CW, Chou SW, Lin CC, Sun YJ. Calcium binds to lipl32, a lipoprotein from pathogenic leptospira, and modulates fibronectin binding.. J Biol Chem.2010, 29;285(5):3245-52.

6.          Yang CW*. Leptospirosis renal disease: understanding the initiation by toll-like receptors .Kidney Int,2007, 72(8):918-25.

7.          Tian YC, Chen YC, Hung CC, Chang CT, Wu MS, Phillips AO, Yang CW*. Leptospiral outer membrane protein induces extracellular matrix accumulation through a tgf-{beta}1/smad-dependent pathway. J Am Soc Nephrol,2006, 17(10): 2792-8.

8.          Yang CW*, Hung CC, Wu MS, Tian YC, Chang TZ, Pan MJ, Vadewalle A. Toll-like receptor 2 mediates early inflammation by leptospiral outer membrane proteins in proximal tubule cells. Kidney Int,2006, 69. 815–822.

9.          Yang CW*, Wu MS, Pan MJ, Hsieh WJ, Vandewalle A, Huang CC. The leptospira outer membrane protein lipl32 induces tubulointerstitial nephritis-mediated gene expression in mouse proximal tubule cells. J Am Soc Nephrol,2002, 13, 2037-2045.

10.      Yang CW*, Wu MS, Pan MJ, Hong JJ, Yu CC, Vandewalle A, Huang CC. Leptospira outer membrane protein activates nf-kappa b and downstream genes expressed in medullary thick ascending limb cells. J Am Soc Nephrol.,2000, 11(11), 2017-2026.