PROFESSIONAL POST

Aug. 1998 to present, Attending of Nephrology, Department of Nephrology, Chang Gung Memorial Hospital, Linkou, Taiwan

July 2009 to present, Chief of Division of Clinical Nephrology and Peritoneal Dialysis, Department of Nephrology, Chang Gung Memorial Hospital, Linkou, Taiwan

July 2004, Assistant Professor, Chang Gung Memorial Hospital, Linkou, Taiwan

July 2005, Assistant Professor, Chang Gung University, Linkou,Taiwan

July 2008, Associate Professor, Chang Gung Memorial Hospital, Taipei, Taiwan

August 2009, Associate Professor, Chang Gung University, Linkou, Taiwan

Education

          October 1986  ~ June 1993: Bachelor of Medicine, Kaoshiung Medical College, Kaoshiung, Taiwan

          July 1992 ~ June 1993: Intern of Medicine, Kaoshiung Medical College, Kaoshiung, Taiwan

          October 2000 ~ June 2003: Philosophiae Doctor, Cardiff University, United Kingdom

RESEARCH INTEREST

Tubulointerstitial fibrosis, polyomavirus-associated nephropathy, peritoneal dialysis

AWARD

腎臟科陳萬裕研究獎 in 2007 and the best presentation of the basic research of Taiwan Society of Nephrology in 2007 and 2011.

Professional ACTIVITIES

Attending physician of Nephrology during daytime

Renal research during nighttime

Education of medical students: any time

MAJOR BIBLIOGRAPHY (limited 10 papers)

1. Acute renal failure in cirrhotic patients with severe sepsis: value of urinary interleukin-18. Tsai MH, Chen YC, Yang CW, Jenq CC, Fang JT, Lien JM, Hung CC, Weng HH, Wu CS, Peng YS, Shen CH, Tung SY, Tian YC* J Gastroenterol Hepatol. 2013 Jan;28(1):135-41.

2. Li YJ, Wu HH, Weng CH, Chen YC, Hung CC, Yang CW, Wang RY, Sakamoto N, Tian YC*. Cyclophilin A and nuclear factor of activated T cells are essential in cyclosporine-mediated suppression of polyomavirus BK replication.  Am J Transplant. 2012 Sep;12(9):2348-62 (IF=6.394; R/C=1/24 TRANSPLANTATION, 2/199 SURGERY)

3.Tian YC*, Hung CC, Li YJ, Chen YC, Chang MY, Yen TH, Hsu HH, Wu MS, Phillips AO, Yang CW. Leptospira santorosai serovar Shermani detergent extract induced an increases in fibronectin production through a toll-like receptor2-mediated pathway  Infect Immun. 2011 Mar;79(3):1134-42 (IF=4.165; R/C=12/70 INFECTIOUS DISEASES, 33/139 IMMUNOLOGY)

4. Comparable ten-year outcome in hemodialysis patients with hepatitis C virus and hepatitis B virus coinfection and single hepatitis B virus infection Blood Purif. 2011;32(2):89-95. . Lee CC, Li IJ, Chen YC, Cheng JW, Wu HH, Weng CH, Fang JT, Tian YC*.

5. Li YJ, Weng CH, Lai WC, Wu HH, Chen YC, Hung CC, Yang CW, Tian YC*. A suppressive effect of cyclosporine on replication and non-coding control region activation of polyomavirus BK virus Transplantation. 2010 Feb 15;89(3):299-306. (IF=4.003, R/C=4/24 TRANSPLANTATION, 11/199 SURGERY)

6. Chang CT, Hung CC, Chen YC, Yen TH, Wu MS, Yang CW, Phillips A, Tian YC*  Transforming growth factor-b1 decreases epithelial sodium channel functionality in renal collecting duct cells via a Smad4-dependent pathway.  Nephrol Dial Transplant. 2008 Apr;23(4):1126-34

7. Tian YC*, Chen YC, Chang CT, Hung CC, Wu MS, Phillips A, Yang CW.  Epidermal growth factor and transforming growth factor-beta1 enhance HK-2 cell migration through a synergistic increase of matrix metalloproteinase and sustained activation of ERK signaling pathway. Exp Cell Res. 2007 Jul 1; 313 (11): 2367-77. (IF=3.580, R/C=57/196 ONCOLOGY, 80/181 CELL BIOLOGY)

8. Tian YC, Phillips AO  TGF-b1-mediated inhibition of HK-2 cell migration.  J Am Soc Nephrol 14(3): 631-40, 2003 (IF=9.663, R/C=1/73 UROLOGY & NEPHROLGOY)

9. Tian YC, Phillips AO  Interaction between the TGF-b1 type II receptor/Smad pathway and b-catenin during TGF-b1  mediated adherens junction disassembly.  Am J Pathol 160: 1619–1628, 2002