1. Lu CH, Lian WS, Wu RW, Lin YH, Su CH, Chen CL, Tai MH, Chen YS, Wang SY, Wang FS*. Iodinated gadolinium-gold nanomaterial as a multimodal contrast agent for cartilage tissue image. APL Bioengineering 2024;8:036110
  2. Lian WS, Wu RW, Lin YH, Chen YS, Jahr H, Wang FS*. Tricarboxylic acid cycle regulation of metabolic program, redox system, and epigenetic remodeling for bone health and disease. Antioxidants 2024;13:470.
  3. Lian WS, Wu RW, Ko JY, Chen YS, Wang SY, Jahr H, Wang FS*. Inhibition of histone lysine demethylase 6A mitigates chondrocyte dysfunction and delays osteoarthritis through H3K27me3 repression of Wnt10a. The International Journal of Biochemistry & Cell Biology 2023;158:106394.
  4. Wen SW, Wu JC, Shen FC, Chang YH, Su YJ, Lian WS, Tai MH, Su CH, Chung JH, Lin TK, Liou CW, Chu TH, Kao YH, Wang FS*, Wang PW*. Chaperonin counteracts diet-induced nonalcoholic fatty liver disease (NAFLD) through escorting SIRT3 control of fatty acid oxidation. Diabetologia 2023;66:913-930.
  5. Ko JY, Wang FS, Lian WS, Fang HC, Kuo SJ. (2023, Jul). Cartilage-specific knockout of miRNA-128a expression normalizes the expression of circadian clock genes (CCGs) and mitigates the severity of osteoarthritis. Biomed J., 13:100629. doi: 10.1016/j.bj.2023.100629.
  6. Yang YL, Huang YH, Wang FS, Tsai MC, Chen CH, Lian WS. (2023, Jul). MicroRNA-29a Compromises Hepatic Adiposis and Gut Dysbiosis in High Fat Diet-Fed Mice via Downregulating Inflammation. Mol Nutr Food Res., 67(13):e2200348.
  7. Lian WS, Wu RW, Ko JY, Chen YS, Wang SY, Jahr H, Wang FS. (2023, May). Inhibition of histone lysine demethylase 6A promotes chondrocytic activity and attenuates osteoarthritis development through repressing H3K27me3 enhancement of Wnt10a. Int J Biochem Cell Biol., 158:106394.
  8. Weng SW, Wu JC, Shen FC, Chang YH, Su YJ, Lian WS, Tai MH, Su CH, Chuang JH, Lin TK, Liou CW, Chu TH, Kao YH, Wang FS, Wang PW.. Chaperonin counteracts diet-induced non-alcoholic fatty liver disease by aiding sirtuin 3 in the control of fatty acid oxidation. Diabetologia., 66(5):913-930.
  9. Hu ML, Lian WS, Wang FS, Yang CH, Huang WT, Yang JW, Chen IY, Yang MY. (2022, Aug). Presume Why Probiotics May Not Provide Protection in Inflammatory Bowel Disease through an Azoxymethane and Dextran Sodium Sulfate Murine Model. Int J Mol Sci., 23(17):9689.
  10. Lian WS, Wu RW, Ko JY, Chen YS, Wang SY, Yu CP, Jahr H, Wang FS. (2022, Jun). Histone H3K27 demethylase UTX compromises articular chondrocyte anabolism and aggravates osteoarthritic degeneration. Cell Death Dis., 13(6):538.
  11. Jahr H, van der Windt AE, Timur UT, Baart EB, Lian WS, Rolauffs B, Wang FS, Pufe T. (2022, May). Physosmotic Induction of Chondrogenic Maturation Is TGF-β Dependent and Enhanced by Calcineurin Inhibitor FK506. Int J Mol Sci., 23(9):5110.
  12. Lian WS, Wang FS, Chen YS, Tsai MH, Chao HR, Jahr H, Wu RW, Ko JY. (2022, Apr). Gut Microbiota Ecosystem Governance of Host Inflammation, Mitochondrial Respiration and Skeletal Homeostasis. Biomedicines., 10(4):860.
  13. Huang YH, Lian WS, Wang FS, Wang PW, Lin HY, Tsai MC, Yang YL. (2022, Jan). MiR-29a Curbs Hepatocellular Carcinoma Incidence via Targeting of HIF- 1α and ANGPT2. Int J Mol Sci., 23(3):1636.
  14. Yang CH, Hwang CF, Chuang JH, Lian WS, Wang FS, Yang MY. (2021, Nov). Systemic toll-like receptor 9 agonist CpG oligodeoxynucleotides exacerbates aminoglycoside ototoxicity. Hear Res., 411:108368.
  15. Kuo HF, Liu IF, Li CY, Tsai CS, Chen YH, Lian WS, Lin TC, Liu YR, Lee TY, Huang CY, Hsieh CC, Hsu CH, Lin FY, Liu PL. (2021, Oct). Endocardial Endothelial Dysfunction and Unknown Polymorphic Composite Accumulation in Heart Failure. Biomedicines., 9(10):1465.
  16. Hsu CH, Liu IF, Kuo HF, Li CY, Lian WS, Chang CY, Chen YH, Liu WL, Lu CY, Liu YR, Lin TC, Lee TY, Huang CY, Hsieh CC, Liu PL. (2021, Sep). miR- 29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis. Int J Mol Sci., 22(19):10574.
  17. Lian WS, Wu RW, Chen YS, Ko JY, Wang SY, Jahr H, Wang FS. (2021, Aug). MicroRNA-29a Mitigates Osteoblast Senescence and Counteracts Bone Loss through Oxidation Resistance-1 Control of FoxO3 Methylation. Antioxidants (Basel)., 10(8):1248.
  1. Lian WS, Wu RW, Chen YS, Ko JY, Wang SY, Jahr H, Wang FS. (2021, Aug). MicroRNA-29a in Osteoblasts Represses High-Fat Diet-Mediated Osteoporosis and Body Adiposis through Targeting Leptin. Int J Mol Sci., 22(17):9135.
  2. Wang FS, Wu RW, Chen YS, Ko JY, Jahr H, Lian WS. (2021, Aug). Biophysical Modulation of the Mitochondrial Metabolism and Redox in Bone Homeostasis and Osteoporosis: How Biophysics Converts into Bioenergetics. Antioxidants (Basel), 10(9):1394.
  3. Wu RW, Lian WS, Chen YS, Ko JY, Wang SY, Jahr H, Wang FS. (2021, Aug). Piezoelectric Microvibration Mitigates Estrogen Loss-Induced Osteoporosis and Promotes Piezo1, MicroRNA-29a, and Wnt3a Signaling in Osteoblasts. Int J Mol Sci., 22(17):9476.
  4. Tsao CF, Chang YH, Shen FC, Su YJ, Lin HY, Chang CS, Lin CY, Lian WS, Chuang JH, Lin TK, Liou CW, Wang PW, Weng SW. (2021). Legacy Effect of Antioxidant N-acetylcysteine in Cellular Senescence of Diet-induced Obesity Mice. Curr Mol Med., 21(6):506-525.
  5. Tsao CF, Chang YH, Shen FC, Su YJ, Lin HY, Chang CS, Lin CY, Lian WS, Chuang JH, Lin TK, Liou CW, Wang PW, Weng SW. (2020, Nov). Legacy Effect of Antioxidant N-acetylcysteine in Cellular Senescence of Diet-induced Obesity Mice. Curr Mol Med., PMID: 33191885.
  6. Yang CH, Hwang CF, Chuang JH, Lian WS, Wang FS, Huang EI, Yang MY. (2020, Oct). Constant Light Dysregulates Cochlear Circadian Clock and Exacerbates Noise-Induced Hearing Loss. Int J Mol Sci., 21(20):7535.
  7. Wang FS, Kuo CW, Ko JY, Chen YS, Wang SY, Ke HJ, Kuo PC, Lee CH, Wu JC, Lu WB, Tai MH, Jahr H, Lian WS. (2020, Sep). Irisin Mitigates Oxidative Stress, Chondrocyte Dysfunction and Osteoarthritis Development through Regulating Mitochondrial Integrity and Autophagy. Antioxidants (Basel)., 9(9):810.
  8. Chen YS, Lian WS, Kuo CW, Ke HJ, Wang SY, Kuo PC, Jahr H, Wang FS. (2020, Jul). Epigenetic Regulation of Skeletal Tissue Integrity and Osteoporosis Development. Int J Mol Sci., 21(14):4923.
  9. Lin HY, Weng SW, Shen FC, Chang YH, Lian WS, Hsieh CH, Chuang JH, Lin TK, Liou CW, Chang CS, Lin CY, Su YJ, Wang PW. (2020, Jul). Abrogation of Toll-Like Receptor 4 Mitigates Obesity-Induced Oxidative Stress, Proinflammation, and Insulin Resistance Through Metabolic Reprogramming of Mitochondria in Adipose Tissue. Antioxid Redox Signal, 33(2):66-86.
  1. Wang FS, Chen YS, Ko JY, Kuo CW, Ke HJ, Hsieh CK, Wang SY, Kuo PC, Jahr H, Lian WS. (2020, Jun). Bromodomain Protein BRD4 Accelerates Glucocorticoid Dysregulation of Bone Mass and Marrow Adiposis by Modulating H3K9 and Foxp1. Cells, 9(6):1500.
  2. Ko JY, Lian WS, Tsai TC, Chen YS, Hsieh CK, Kuo CW, Wang FS. (2019, Nov). MicroRNA-29a Mitigates Subacromial Bursa Fibrosis in Rotator Cuff Lesion with Shoulder Stiffness. Int J Mol Sci., 20(22). pii: E5742.
  3. Wu RW, Lian WS, Kuo CW, Chen YS, Ko JY, Wang FS. (2019, Nov). S100 Calcium Binding Protein A9 Represses Angiogenic Activity and Aggravates Osteonecrosis of the Femoral Head. Int J Mol Sci, 20(22). pii: E5786.
  4. Wu RW, Lian WS, Chen YS, Kuo CW, Ke HC, Hsieh CK, Wang SY, Ko JY, Wang FS. (2019, Oct). MicroRNA-29a Counteracts Glucocorticoid Induction of Bone Loss through Repressing TNFSF13b Modulation of Osteoclastogenesis. Int J Mol Sci, 20(20). pii: E5141.
  5. Lian WS, Ko JY, Chen YS, Ke HJ, Hsieh CK, Kuo CW, Wang SY, Huang BW, Tseng JG, Wang FS. (2019, Sep). MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12. Cell Death Dis, 10(10):705.
  6. Shen FC, Weng SW, Tsao CF, Lin HY, Chang CS, Lin CY, Lian WS, Chuang JH, Lin TK, Liou CW, Wang PW. (2018, Oct). Early intervention of N-acetylcysteine better improves insulin resistance in diet-induced obesity mice. Free Radic Res, 52(11-12):1296-1310.
  7. Lian WS, Ko JY, Chen YS, Ke HJ, Wu SL, Kuo CW, Wang FS (2018, Sep). Chaperonin 60 sustains osteoblast autophagy and counteracts glucocorticoid aggravation of osteoporosis by chaperoning RPTOR. Cell Death Dis, 9(10):938.
  8. Lian WS, Ko JY, Wu RW, Sun YC, Chen YS, Wu SL, Weng LH, Jahr H, Wang FS (2018, Sep). MicroRNA-128a represses chondrocyte autophagy and exacerbates knee osteoarthritis by disrupting Atg12. Cell Death Dis, 9(9):919.
  9. Wang FS, Wu RW, Lian WS, Tsai TC, Chen YS, Sub YC, Ke HJ, Li JC, Hwang JL, Ko JY. (2018, Apr). Sclerostin Vaccination Mitigates Estrogen Deficiency Induction of Bone Mass Loss and Microstructure Deterioration Bone. BONE, 12:24-34.