Yuh-Jin Liang Ph.D.
Office Address:
12J, No.5, Fu-Shin St., Kuei Shang, Taoyuan 333, Taiwan
Tel: +8863-3281200#8067
E-mail: yuh.jin.liang@gmail.com
Education:
1995-1998 Research Technician, Graduate Institute of Microbiology, College of Medicine National Taiwan University.
1998-2008 Research Technician, Institute of Cancer Research, National Health Research Institute.
2008-2011 Postdoctoral Fellow, Stem Cell program, Genomics Research Center, Academia Sinica. 2011-2013 Postdoctoral Fellow, Departments of Pathobiology and Global Health Health, University of Washington
2013-Present Assistant Professor, Stem Cell and Translation Cancer Research Institute, Chang Gung Memorial Hospital.
Honor and Awards:
1. Liang YJ, Ding Y. Steve B. Levery, Handa K, Hakomori SI: Differential Expression Profiles of Glycosphingolipids in Human Breast CSCs vs. Non-CSCs. Proc Natl Acad Sci U S A 2013, 110:4968-4973.
2. Liang YJ, Yang BC, Chen JM, Lin YH, Huang CL, Cheng YY, Hsu CY, Khoo KH, Shen CN, Yu J: Changes in Glycosphingolipid Composition During Differentiation of Human Embryonic Stem Cells to Ectodermal or Endodermal Lineages. Stem Cells 2011, 29:12, 1995-2004.
3. Liang YJ, Kuo HH, Lin CH, Chen YY, Yang BC, Cheng YY, Yu AL, Khoo KH, Yu J: Switching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiation. Proc Natl Acad Sci U S A 2010, 107:22564-22569.
4. Chang HS, Lin CH, Yang CH, Liang YJ, Yu WC: The human papillomavirus-16 (HPV-16) oncoprotein E7 conjugates with and mediates the role of the transforming growth factor-beta inducible early gene 1 (TIEG1) in apoptosis. Int J Biochem Cell Biol 2010, 42:1831-1839.
5. Liang YJ, Chang HS, Wang CY, Yu WC: DYRK1A stabilizes HPV16E7 oncoprotein through phosphorylation of the threonine 5 and threonine 7 residues. Int J Biochem Cell Biol 2008, 40:2431-2441.
6. Chang HS, Lin CH, Yang CH, Yen MS, Lai CR, Chen YR, Liang YJ, Yu WC: Increased expression of Dyrk1a in HPV16 immortalized keratinocytes enable evasion of apoptosis. Int J Cancer 2007, 120:2377-2385.
7. Wang CY, Liang YJ, Lin YS, Shih HM, Jou YS, Yu WC: YY1AP, a novel co-activator of YY1. J Biol Chem 2004, 279:17750-17755.
Office Address:
12J, No.5, Fu-Shin St., Kuei Shang, Taoyuan 333, Taiwan
Tel: +8863-3281200#8067
E-mail: yuh.jin.liang@gmail.com
Education:
2002-2008 Ph.D., National Defense Medical Center, Graduate Institute of life science
1996-1998 M.S., National Chung Hsing University, Institute of Molecular Biology
1995-1998 Research Technician, Graduate Institute of Microbiology, College of Medicine National Taiwan University.
1998-2008 Research Technician, Institute of Cancer Research, National Health Research Institute.
2008-2011 Postdoctoral Fellow, Stem Cell program, Genomics Research Center, Academia Sinica. 2011-2013 Postdoctoral Fellow, Departments of Pathobiology and Global Health Health, University of Washington
2013-Present Assistant Professor, Stem Cell and Translation Cancer Research Institute, Chang Gung Memorial Hospital.
Honor and Awards:
- Ph.D. Student Thesis Research Award ,2008 June
- Awardees of Academia Sinica Postdoctoral Research Fellowships, 2010 July.
- Awardees of Travel Award of the Society for Glycobiology and the American Society for Matrix Biology, 2012 November.
1. Liang YJ, Ding Y. Steve B. Levery, Handa K, Hakomori SI: Differential Expression Profiles of Glycosphingolipids in Human Breast CSCs vs. Non-CSCs. Proc Natl Acad Sci U S A 2013, 110:4968-4973.
2. Liang YJ, Yang BC, Chen JM, Lin YH, Huang CL, Cheng YY, Hsu CY, Khoo KH, Shen CN, Yu J: Changes in Glycosphingolipid Composition During Differentiation of Human Embryonic Stem Cells to Ectodermal or Endodermal Lineages. Stem Cells 2011, 29:12, 1995-2004.
3. Liang YJ, Kuo HH, Lin CH, Chen YY, Yang BC, Cheng YY, Yu AL, Khoo KH, Yu J: Switching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiation. Proc Natl Acad Sci U S A 2010, 107:22564-22569.
4. Chang HS, Lin CH, Yang CH, Liang YJ, Yu WC: The human papillomavirus-16 (HPV-16) oncoprotein E7 conjugates with and mediates the role of the transforming growth factor-beta inducible early gene 1 (TIEG1) in apoptosis. Int J Biochem Cell Biol 2010, 42:1831-1839.
5. Liang YJ, Chang HS, Wang CY, Yu WC: DYRK1A stabilizes HPV16E7 oncoprotein through phosphorylation of the threonine 5 and threonine 7 residues. Int J Biochem Cell Biol 2008, 40:2431-2441.
6. Chang HS, Lin CH, Yang CH, Yen MS, Lai CR, Chen YR, Liang YJ, Yu WC: Increased expression of Dyrk1a in HPV16 immortalized keratinocytes enable evasion of apoptosis. Int J Cancer 2007, 120:2377-2385.
7. Wang CY, Liang YJ, Lin YS, Shih HM, Jou YS, Yu WC: YY1AP, a novel co-activator of YY1. J Biol Chem 2004, 279:17750-17755.