Expertise at Chang Gung System

Chiang, Kun-Chun , M.D.,Ph.D.
Intitution: Chang Gung Memorial Hospital
Position: Physician/Associate professor
Department: General surgery department
Address:222 Mai Chin Road, Keelung, Taiwan. (R.O.C.)
Tel: 886-2-4313131 EXT2613 Fax:+886-2-24332655
E-mail: robertviolet6292@yahoo.com.tw

Focus of Interest:
  • Biochemistry and Molecular Biology - Medicine
  • Critical Care Medicine
  • Medical Technology, and Clinical Pathology
  • Nutrition & Dietetics
  • Oncology
  • Surgery

Fulltime Employment:
  1. 2005-2007 General Surgical Attending Division of General Surgery Department of Surgery Chang-GungMemorialHospital at Keelung
  2. 2007-2009 Fellow of Boston medical center Fellow of Boston endocrine Laboratory
  3. 2009~ General Surgical Attending Division of General Surgery Department of Surgery Chang-GungMemorialHospital at Keelung

Education:
  • 1991-1998 Yan-Ming medical University Bachelor of Medicine
  • 2011-2013 PhD degree, Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University

Selected Main Publications:
  1. Chiang KC, Yeh CN, Lin KJ, Su LJ, Yen TC, Pang JH, Kittaka A, Sun CC, Chen MF, Jan YY, Chen TC, Juang HH, Yeh TS. Chemopreventive and chemotherapeutic effect of dietary supplementation of vitamin D on cholangiocarcinoma in a Chemical-Induced animal model. Oncotarget. 2014 Jun 15;5(11):3849-61.
  2. Kun-Chun Chiang, Chun-Nan Yeh, Jun-Te Hsu, Ta-sen Yeh, Yi-yin Jan, Chun-Te Wu, Huang-Yang Chen, Shyh-Chuan Jwo, Masashi Takano, Atsushi Kittaka, Horng-Heng Juang and Tai C. Chen. Evaluation of the potential therapeutic role of a new generation of vitamin D analog, MART-10, in human pancreatic cancer cells in vitro and in vivo. Cell Cycle. 2013 Apr 15;12(8):1316-25. doi: 10.4161/cc.24445. Epub 2013 Apr 2.
  3. Chiang KC, Yeh CN, Hsu JT, Jan YY, Chen LW, Kuo SF, Takano M, Kittaka A, Chen TC, Chen WT, Pang JH, Yeh TS, Juang HH.The vitamin D analog, MART-10, represses metastasis potential via downregulation of epithelial-mesenchymal transition in pancreatic cancer cells. Cancer Lett. 2014 Aug 19. pii: S0304-3835(14)00449-2. doi: 10.1016/j.canlet.2014.08.019. [Epub ahead of print]
  4. Chiang KC, Tsui KH, Chung LC, Yeh CN, Feng TH, Chen WT, Chang PL, Chiang HY, Juang HH.Cisplatin modulates B-cell translocation gene 2 to attenuate cell proliferation of prostate carcinoma cells in both p53-dependent and p53-independent pathways. Sci Rep. 2014 Jul 1;4:5511. doi: 10.1038/srep05511.
  5. Chiang KC, Chen SC, Yeh CN, Pang JH, Shen SC, Hsu JT, Liu YY, Chen LW, Kuo SF, Takano M, Kittaka A, Sun CC, Juang HH, Chen TC. MART-10, a less calcemic vitamin D analog, is more potent than 1α,25-dihydroxyvitamin D3 in inhibiting the metastatic potential of MCF-7 breast cancer cells in vitro.. J Steroid Biochem Mol Biol. 2014 Jan;139:54-60. doi: 10.1016/j.jsbmb.2013.10.005. Epub 2013 Oct 12.
Full Publication List

Board Certification:
 1. Medical doctor license
 2. Taiwan Surgical association, license
 3. Surgery doctor license
 4. GI tract surgery doctor license

Ongoing projects:
1) Investigation NGAL role in human cholangiocarcinoma and development of new treatment against cholangiocarcinoma
2) Investigation of oral supplementof vitamin D to prevent and treat cholangicarcinoma and the ability of cholangiocarcinoma cells to convert 25(OH)D to 1,25(OH)2D3
3) Investigation of the effect of vitamin D and its analog on angiogenesis