Hong JH

Hong, Ji-Hong,M.D.,Ph.D.
Institution: Chang Gung Memorial Hospital/Chang Gung University
Position: Vice superintendent / Physician / Professor
Department: Radiation Oncology (CGMH), Institute of Radiation Research
Address: No.5, Fusing St., Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.)
Tel: +886-3-3281200 ext 7006
E-mail: jihong@adm.cgmh.org.tw

Focus of Interest :

• Radiation oncology(GU, Gyn. and GI)
• Radiation Biology
• Molecular imaging

Employment Records：
◎ 8/2014 – present    Vice superintendent, Chang Gung Memorial Hospital at Lin-kou
◎ 1/2010 – 2012    Director of Cancer Center, Chang Gung Memorial Hospital
◎ 1/2004 – 2010    Vice director of Cancer Center, Chang Gung Memorial Hospital
◎ 1/2000 –12/2003   Director of Cancer Center, Chang Gung Memorial Hospital
◎ 10/1997 – 6/2014    Director, Department of Radiation Oncology, Chang Gung Memorial Hospital
◎ 7/1995- 10/1997    Attending physician, Department of Radiation Oncology, Chang Gung Memorial Hospital
◎ 4/1995 - 6/1995    Post-doctor in Department of Radiation Oncology, Experimental Division, UCLA
◎ 7/1991 - 3/1995    Research Assistant in Department of Radiation Oncology, Experimental Division, UCLA
◎ 7/1988 - 8/1990    Attending physician, Department of Radiation Oncology, Chang Gung Memorial Hospital
◎ 7/1984 - 6/1988    Resident and Chief resident, Department of Radiation Oncology, Chang Gung Memorial Hospital
◎ 6/1977 - 6/1984    Rotating internship, Chang Gung Memorial Hospital

Education:
》9/1990 - 3/1995 Ph.D., Biomedical Physics Program, UCLA
》9/1977 - 6/1984 M.D., Taipei Medical School

Honors and Awards:
“A” class Research Award from National Science Council, R.O.C.

Main Publications:

1. F.H. Chen, S.Y. Fu, Y.C. Yang, C.C. Wang, C.S. Chiang and J. H. Hong*  Combination of vessel-targeting agents and fractionated radiation therapy: the role of the SDF-1/CXCR4 pathway. Int. J. Radiat. Oncol. Biol. Phys., 2013,  86: 777-784 (SCI)
2. F. H. Chen, C. S. Chiang, C. C. Wang, S. Y. Fu, C. S. Tsai, S. M. Jung, C. J. Wen, C. C. Lee, and J. H. Hong* Vasculatures in Tumors Growing from Preirradiated Tissues: Formed by Vasculogenesis and Resistant to Radiation and Antiangiogenic Therapy. Int. J. Radiat. Oncol. Biol. Phys., 2011,  80: 1512-1521 (SCI)
3. F. H. Chen, C. S. Chiang, C. C. Wang, C. S. Tsai, S. M. Jung, C. C. Lee, W. H. McBride, and J. H. Hong*: Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors.  Clin. Cancer Res. 15:1721-1729, 2009 (SCI)
4. C. S. Tsai, F. H. Chen, C. C. Wang, H. L. Huang, S. M. Jung, C. J. Wu, C. C. Lee, W. H. McBride, C. S. Chiang and J. H. Hong*: Macrophages from irradiated tumors express higher levels of Arginase-I and COX-2, and promote tumor growth. Int. J. Radiat. Oncol. Biol. Phys., 68: 499-507, 2007 (SCI)
5. J. H. Hong, C. S. Chaing, I. L. Campbell, J. R. Sun, H. R. Withers and W. H. McBride: Induction of acute phase gene expression by brain irradiation.  Int. J. Radiat. Oncol. Biol. Phys. 33: 619-626, 1995 (SCI)

Full Publication List

Board Certification:
 -Board certificated radiation oncologist by Taiwan Society for Therapeutic Radiology and Oncology
Membership:
(1) American Association of Cancer Research (AACR)
(2) American Society for Radiation Oncology (ASTRO)
(3) Radiation Research Society (RRS)
(4) International Gynecologic Cancer Society (IGCS)
(5) Taiwan Society for Therapeutic Radiology and Oncology
(6) Chinese Society for Medical Physics

Ongoing projects:
1. Changes of tumor microenvironment after high-dose irradiation; Role of inflammatory cells and bone marrow derived stem cells in irradiated tumor microenvironment.
2. Combination of immune therapy and radiotherapy in animal tumor model.
3. Application of functional imaging in studying changes of tumor microenvironment after high-dose irradiation.
4. Proton target therapy for liver cancer: combination of physics, imaging and biology.