Expertise at Chang Gung System

Pi-yueh Chang ,Ph.D.
Institution:Linkou chang gung memorial hospital / Chang gung university
Position: Deputy chief medical technologist/ Lecturer
Department: Department of Laboratory Medicine/ Department of Medical Biotechnology and Laboratory Science
Address: No.5, Fusing St., Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.) / No.259, Wenhua 1st Rd., Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.)
Tel: +886-3-3281200 ext 5150
E-mail: changpy@adm.cgmh.org.tw


Focus of Interest :
  • Medical Educate
  • Medical Technology, and Clinical Pathology
  • Molecular Biology

Employment Records:
 ● 08/1994- present Lecturer, Department of Medical Biotechnology and Laboratory Science, Chang Gung University
 ● 03/2002- 06/2008 Supervisor, Section of Research and Development, Department of Laboratory Medicine, Chang Gung Memorial Hospital
 ● 12/2005- 06/2008 Supervisor, Section of Molecular Pathology, Department of Laboratory Medicine, Chang Gung Memorial Hospital
 ● 07/2008- present Deputy Chief Technologist of Laboratory Medicine, Chang Gung Memorial Hospital

Education:
 》 09/1988-06/1992 BS of Medical Technology, College of Medicine, National Taiwan University
 》 09/1992-06/1994 MS of Medical Technology, College of Medicine, National Taiwan University
 》 09/2010~present PHD of Medical Biotechnology and Laboratory Science, Chang Gung University

Main Publications:

  1. Pi-Yueh Chang, Tsu-Lan Wu, Chung-Chih Hung, Kuo-Chien Tsao, Chien-Feng Sun, Lily L. Wu and James T. Wu. Development of an ELISA for myeloperoxidase on microplate: Normal reference values and effect of temperature on specimen preparation Clin Chim Acta 2006,373: 158-163
  2. Pi-Yueh Chang, Tsu-Lan Wu, Huan-Tang Chen, Kuo-Chien Tsao, Chien-Feng Sun, Lily L Wu, James T Wu. Acute inflammatory response of cosmetic liposuction causes only a transient elevation of acute inflammatory markers and does not advance to oxidative and nitrosative stress. J Clin Lab Anal 2007 ;21:418-425
  3. Pi-Yueh Chang, Yung-Bin Kuo ,Tsu-Lan Wu, Chun-Ta Liao, Yu-Chen Sun, Tzu-Chen Yen , Err-Cheng Chan. Association and Prognostic Value of Serum Inflammation Markers in Patients with Leukoplakia and Oral Cavity Cancer. Clinical Chemistry and Laboratory Medicine 2013; 51(6): 1291–1300 (SCI IF= 2.955)
  4. Pi-Yueh Chang, Cheng-Tao Yang, Ching-Hui Cheng, Kuang-Hui Yu. Diagnostic Performance of Anti-cyclic Citrullinated Peptide and Rheumatoid Factor in Patients with Rheumatoid Arthritis. International Journal of Rheumatic Diseases 2015. doi: 10.1111/1756-185X.12552 (SCI IF:1.771)
  5. Pi-Yueh Chang, Chia-Chun Chen, Yu-Sun Chang, Wen-Sy Tsai, Jeng-Fu You, Geng-Ping Lin, Ting-Wen Chen, Jinn-Shiun Chen, Err-Cheng Chan. MicroRNA-223 and microRNA-92a in stool and plasma samples act as complementary biomarkers to increase colorectal cancer detection. Oncotarget, Advance Publications 2016; February 01
Full Publication List

Board Certification / Professional Affiliations:

 -Taiwan Association of Medical Technologist, 1994 - present
 -Taiwan Society of Laboratory Medicine, 1994-present

Ongoing projects:

                                           
ProjectRole Period Grant support Budget (NTD)
Analysis of gut and fecal microbiota from patients with colorectal cancer and polyps by next generation sequencing of 16S rRNA genesPI 105/1/1-105/12/30 CGMH 712,755
Development of circulating anti-colorectal cancer associated autoantibodies and microRNAs as biomarkers for detection of colorectal cancerCO-PI 103/10/1-105/9/30 CGMH 8,000,000
Application of screening of colorectal cancer associated mutation genes by next generation sequencerCO-PI 102/8/1-105/7/31 CGMH 5,600,000
The applications of next generation sequence for gout and hyperuricemia related gene screeningCO-PI 102/8/1-105/7/31 CGMH 4,800,000
Mutation screening for children with cochlear implants by using next generation sequencerCO-PI 102/8/1-105/7/31 CGMH 5,128,850