Institution: Chang Gung Memorial Hospital
Position: Professor
Department: Hepatology and Gastroenterology
Address: No. 5, Fu-Shing Street, Kueishan, Taoyuan 333, Taiwan.
Tel: +886-3-3281200 ext:8107 / +886-3-3285056
E-mail: chunyenlin@gmail.com
Focus of Interest:
- Cellular Immunology
- Tumor Immunology
- Viral immunology
- Liver immunology
Main interest is to bridge the basic study, translational study and clinical study based on an immunological foundation. The main research fields are listed below:
- Basic Studies: Immune mechanisms of immune regulation: using mice model to explore the suppression mechanisms of different regulatory immune cells, including regulatory T cells, tolerogenic dendritic cells; tumor-associated macrophage and MDSC A. Immune regulation in tumor immunotherapy: using mice model to develop strategies of tumor immunotherapy, especially to block the inhibition effect of immune regulation.
B. Immune regulation in acute liver injury: using mice model to explore the immune derangement in acute liver injury and to develop possible treatment strategies
Employment Records:
Associate Chairperson, 2011----2015
School of Medicine, College of Medicine;
Chang Gung University; Taoyuan, Taiwan
Vice Chairman, 2012--2016
Committee of Medical Education Chang Gung Memorial Hospital;
Taoyuan, Taiwan
Chief, 2014--2016
Division of Hepatology Chang Gung Memorial Hospital;
Taoyuan, Taiwan
Vice Chairman, 2016--2017
Department of Medical Research Chang Gung Memorial Hospital;
Taoyuan, Taiwan
Deputy Director, 2016--2017
Department of Internal Medicine Chang Gung Memorial Hospital;
Taoyuan, Taiwan
Doctor of Medicine (M.D.), 1980-1987
Taipei Medical University
Taipei, Taiwan
Doctor of Philosophy (Ph.D.), 1997-2002
Sir William Dunn School of Pathology
Lincoln College; Oxford University
Oxford, England
1. Lin YC, Mahalingam J, Chiang JM, Su PJ, Chu YY, Lai HY, Fang JH, Huang CT, Chiu CT, Lin CY*. Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer.
2. Mahalingam J, Lin YC, Chiang JM, Su PJ, Chu YY, Lai HY, Fang JH, Huang CT, Chiu CT, Lin CY*. LAP+CD4+ T cells are suppressors accumulated in the tumor sites and associated with the progression of colorectal cancer.
3. Chang LY, Lin YC, Kan CW, Hsu CY, Chu YY, Huang CT, Day YJ, Chen TC, Yeh CT, Lin CY*. The indispensable role of CCR5 for in vivo suppressor function of CD103+ effector/memory regulatory T cells.
4. Chang LY, Lin YC, Mahalingam J, Huang CT, Chen TW, Kang CW, Peng WM, Chu YY, Chiang JM, Dutta A, Day YJ, Chen TC, Yeh CT, Lin CY*. Tumor-derived chemokine CCL5 enhances TGF-β mediated killing of CD8+ T cells in colon cancer by T regulatory cells.
5. Liu HL, Hsieh HY, Lu LA, Kang CW, Wu MF, Lin CY*. Low-Pressure Pulsed Focused Ultrasound with Microbubbles Promotes an Anticancer Immunological Response.
Full Publication List