Expertise at Chang Gung System

Ho-Chang Kuo , M.D., Ph.D.
Intitution: Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine
Position: Associate Professor
Department: Pediatrics
Mail Address: 123, Da-Pei Rd., Niaosong, Kaohsiung, Taiwan 83301
Tel: +886-7-731-7123 ext.8802
E-mail: erickuo48@yahoo.com.tw , sel7129@adm.cgmh.org.tw

Focus of Interest:
  • Kawasaki disease
  • Allergic disease
  • Rheumatology

Research Summary
Research were focus on immunopathogenesis of Kawasaki disease.  Recently, we found the genetic association of CD40/BLK in the susceptibility of Kawasaki disease that was published on Nature Genetics 2012. We had published more than 40 SCI journal papers of Kawasaki disease including 3 SCI invited review articles, 2 Nature Genetics articles and 4 chapters writing of textbook (Springer, Nova, InTech). We have also constructed blog (http://blog.xuite.net/erickuo48/kawasakidisease) and Facebook group for Kawasaki disease to serve more patients and parents with Kawasaki disease out of hospital.   
Employment Records:

2009 Lectorate attending physician of Chang Gung University, Taiwan.
2010 Assistant Professor of Kaohsiung Chang Gung Memorial Hospital, Taiwan.
2011 Assistant Professor of Chang Gung University, Taiwan.
2013 Associate Professor of Kaohsiung Chang Gung Memorial Hospital, Taiwan.

Education:

MD, 1992-1999, College of Medicine, National Yang-Ming University, Taipei, Taiwan.
PhD, 2004-2011 Graduate Institute of Clinical Medical Science, Chang Gung University, Kaohsiung, Taiwan.

Selected Publications:
1. Khor CC, Davila S,,, Kuo HC, Huang KP, Lee ML,,,etc. Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nat Genet. 2011 Nov 13;43(12):1241-6.

2. Yi-Ching Lee, Ho-Chang Kuo, Jeng-Sheng Chang, Luan-Yin Chang, Li-Min Huang, Ming-Ren Chen, Chi-Di Liang, Hsin Chi, Fu-Yuan Huang, Meng-Luen Lee, Yhu-Chering Huang, Betau Hwang, Nan-Chang Chiu, Kao-Pin Huang, Pi-Chang Lee, Li-Ching Chang, Yi-Min Liu, Ying-Ju Chen, Chien-Hsiun Chen, Taiwan Pediatric ID Alliance , Yuan-Tsong Chen, Fuu-Jen Tsai, Jer-Yuarn Wu. Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. Nature Genetics 2012 Mar 25;44(5):522-5. (Co-1st author)

3. Chia-Yu Ou, Ho-Chang Kuo, Lin Wang, Te-Yao Hsu, Hau-Chuang, Chieh-An Liu, Jen-Chieh Chang, Hong-Ren Yu, Kuender D. Yang. Prenatal and Postnatal Probiotics Reduces Maternal but not Childhood Allergic Diseases: a Randomized, Double-Blind, Placebo-Controlled Trial. Clinical and Experimental Allergy 2012 Sep;42(9):1386-96. (co-1st author) (Selected as Editor’s Choice)

4. Chiu-Ping Lee , Ying-Hsien Huang , Yu-Wen Hsu , Kuender D. Yang , Hsu-Chen Chien , Hong-Ren Yu , Ya-Ling Yang , Chih-Lu Wang , Wei-Chiao Chang, Ho-Chang Kuo*. TARC/CCL17 Gene Polymorphisms and Expression Associated with Susceptibility and the Formation of Coronary Artery Aneurysms in Kawasaki Disease. Pediatric Research (corresponding author*)

5. Ho-Chang Kuo, Yu-Wen Hsu, Chung-Min Wu, Shawn Hsiang-Yin Chen, Kuo-Sheng Hung, Wei-Pin Chang, Kuender D. Yang, Kai-Sheng Hsieh, Wei-Chiao Chen, Yoshihiro Onouchi, and Wei-Chiao Chang. A Replication Study for Association of ITPKC and CASP3 Two-locus analysis in IVIG unresponsiveness and coronary artery lesion in Kawasaki disease. PLoS One. 2013 Jul 24;8(7):e69685.


Honor and Awards:
  • Travel award of 1st Asia Society of Pediatric Research (ASPR), 2005, Tokyo Japan.
  • Physician scientist award, Institute of Biomedical Science, Academia Sinica, 2005, 2006, 2007.
  • The 2007 Annual Best Article Award of resident in all Chang Gung Memorial Hospitals.
  • The best research article of 2008 (Nestle), The Chinese Society of Pediatric Allergy, Asthma and Immunology.
  • 2009 Research award of Professor Wen-Chang Liu, The Chinese Society of Immunology.  
  • Marquis "Who's Who in the World" (2011)
  • 2010 Man of the Year, The American Biographical Institute, ABI.
  • 2011 Pediatric Academic Societies and Asian Society for Pediatric Research (PAS/ASPR) Joint meeting, Denver, Colorado, USA. (ASPR bEST RESEARCH AWARD)
  • The best research article of 2011 (Otsuka respiratory), The Chinese Society of Pediatric Allergy, Asthma and Immunology
  • The 8th Congress of Asian Society for Pediatric Research (ASPR), Seoul, Korea. 2012.-Young Investigators Award (YIA). (CD40 gene polymorphism in Kawasaki disease)
  • The 8th Congress of Asian Society for Pediatric Research (ASPR), Seoul, Korea. 2012.-Young Investigators Award (YIA). (ITPKC and CASP3 gene polymorphism in Kawasaki disease)
  • The 8th Congress of Asian Society for Pediatric Research (ASPR), Seoul, Korea. 2012.-Young Investigators Award (YIA). (Hepcidin in Kawasaki disease).
  • 2013 The National Science Council, Taiwan. (Ta-You Wu Memorial Award. 國科會吳大猷獎)
  • The best research article of 2012 (MSD), The Chinese Society of Pediatric Allergy, Asthma and Immunology.
  • 2012 Research award of Professor Wen-Chang Liu, The Chinese Society of Immunology.
  • 2013 American Academy of Allergy Asthma and Immunology (AAAAI) International Young Investigator Award.
  • 2013 China Youth Corps Youth Metal (救國團青年獎章)
  • 2013 Outstanding Alumni of Chang Gung University. (Chang Gung University was ranked near the top 400 place in the Shanghai Jiao Tong Academic Ranking of World Universities) (長庚大學傑出校友)
  • 國科會101及102年度補助大專校院獎勵特殊優秀人才獎勵
  • 2013 American Academy of Allergy Asthma and Immunology (AAAAI) International Young Investigator Award.
Source:

Mouse strains: none
Cell lines: none
Special technology: none