Expertise at Chang Gung System

Tsai ,Chia-Lung ,Ph.D.
Intitution:Linkou chang gung memorial hospital
Position: Assistant research fellow
Department: Genomic Medicine Research Core Laboratory
Address:Chang-Gung Memorial Hosipital,5, Fu-Shin Street, Kwei-Shan, Taoyuan, Taiwan
Tel:886-3-3281200-8975
cltsai@cgmh.org.tw,cltsai24@gmail.com

Focus of Interest:
  • Molecular Biology
  • Molecular & Cell Biology
  • Oncology
Fulltime Employment:
Research fellow

Education:
 》 Ph.D. Institute of Microbiolgy & Immunolgy, Yang-Ming University, Taipei, Taiwan

Selected Publications:
  1. Tsai CN*, Tsai CL*, Tse KP, Chang HY, Chang YS. The Epstein-Barr virus oncogene product, latent membrane protein 1, induces the downregulation of E-cadherin gene expression via activation of DNA methyltransferases. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10084-9. PubMed PMID: 12110730; PubMed Central PMCID: PMC126628.(* co-first authors)
  2. Tsai CL, Li HP, Lu YJ, Hsueh C, Liang Y, Chen CL, Tsao SW, Tse KP, Yu JS, Chang YS. Activation of DNA methyltransferase 1 by EBV LMP1 Involves c-Jun NH(2)-terminal kinase signaling. Cancer Res. 2006 Dec 15;66(24):11668-76. PubMed PMID: 17178861.
  3. Wang TH*, Chao A*, Tsai CL*, Chang CL, Chen SH, Lee YS, Chen JK, Lin YJ, Chang PY, Wang CJ, Chao AS, Chang SD, Chang TC, Lai CH, Wang HS. Stress-induced phosphoprotein 1 as a secreted biomarker for human ovarian cancer promotes cancer cell proliferation. Mol Cell Proteomics. 2010 Sep;9(9):1873-84. PubMed PMID: 20501939; PubMed Central PMCID: PMC2938116. (* co-first authors)
  4. Tsai CL, Tsai CN, Lin CY, Chen HW, Lee YS, Chao A, Wang TH, Wang HS, Lai CH. Secreted stress-induced phosphoprotein 1 activates the ALK2-SMAD signaling pathways and promotes cell proliferation of ovarian cancer cells. Cell Rep. 2012 Aug 30;2(2):283-93. PubMed PMID: 22884369.
  5. Tsai CL, Wu HM, Lin CY, Lin YJ, Chao A, Wang TH, Hsueh S, Lai CH, Wang HS. Estradiol and tamoxifen induce cell migration through GPR30 and activation of focal adhesion kinase (FAK) in endometrial cancers with low or without nuclear estrogen receptor α (ERα). PLoS One. 2013;8(9):e72999. PubMed PMID: 24039841; PubMed Central PMCID: PMC3767783
Full Publication List