論文發表

01. Lin WY, Chuang CK*,Ng KF, Liao SK
Renal angiomyolipoma with lymph node involvement: a case report and literature review.
Chang Gung Med J. 2003;26(8):607-10.

02. Wu CF, Shee JJ, Lin WY, Lin CL, Chen CS*
Comparison between extracorporeal shock wave lithotripsy and semirigid
ureterorenoscope with holmium:YAG laser lithotripsy for treating large proximal ureteral
stones.
J Urol. 2004;172(5 Pt 1):1899-902.
( SCI; IF=3.862; Urology & Nephrology 10/69 )

03. Wu CF, Chen CS*, Lin WY, Shee JJ, Lin CL, Chen Y, Huang WS
Therapeutic options for proximal ureter stone: extracorporeal shock wave lithotripsy
versus
semirigid ureterorenoscope with holmium:yttrium-aluminum-garnet laser lithotripsy.
Urology. 2005; 5(6):1075-9.
( SCI; IF= 2.334; Urology & Nephrology 26/69 )

04. Chen CS*, Wu CF, Shee JJ, Lin WY,
Holmium:YAG Lasertripsy with semirigid ureterorenoscope for upper-ureteral stones >2
cm.
J Endourol. 2005;19(7):780-4
( SCI; IF= 1.729; Urology & Nephrology 36/69 )

05. Ho DR, Lin WY, Wu CF, Shee JJ, Huang YC and Chen CS
Clinical observations of the effect of antidiuretic hormone on nocturia in elderly men
BJU International. 2005;96(9):1310.
( SCI; IF= 3.19; Urology & Nephrology 14/69 )

06. Huang YC, Ho DR, Wu CF, Shee JJ, Lin WY, Chen CS*
Modified bowel preparation to reduce infection after prostate biopsy.
Chang Gung Med J. 2006;29(4):395-400

07. Lin WY, Wu CF, Shee JJ, Lin CL, Chen CS*
A Decade of Recurrent Cystitis in a Woman Due to a Giant Vesical Calculus.
International Urogynacology Journal. 2006;17: 674-675.
( SCI; IF= 2.368; Urology & Nephrology 25/69)

08. Lin WY, Ho DR, Wu CF, Shee JJ, Huang YC and Chen CS*
Preliminary Study of Electric Stimulation on Premature Ejaculation in Patients with
Chronic Pelvic Pain Syndrome or Chronic Prostatitis
Sexol. 2007;16(1):38-42.

09. Lin WY, Rehfuss A, Whitbeck C, Juan YS, Chichester P, Mannikarottu A, Levin RM*
Effect of Letrozole on urinary bladder function in the female rabbit.
BJU International. 2007;100(6):1391-5.
( SCI; IF= 3.19; Urology & Nephrology 14/69 )

10. Lin WY, Levin RM, Chichester P, Leggett R, Juan YS, Johnson A, Neumann P,
Whitbeck C, Guven A, Kogan B, Mannikarottu AS*
Effects of L-arginine and L-NAME on chronic partial bladder outlet obstruction in rabbit.
Am J Physiol Regul Integr Comp Physiol. 2007;293(6):R2390-9.
( SCI; IF= 3.284; Physiology 24/77 )

11. Guven A, Lin WY, Leggett RE, Kogan BA, Levin RM, Mannikarottu A*
Effect of aging on the response of biochemical markers in the rabbit subjected to
short-term partial bladder obstruction.
Mol Cell Biochem. 2007;306(1-2):213-9.
( SCI; IF= 2.168; Cell biology 122/177 )

12 Juan YS, Lin WY, Carmin Kalorin3, Kogan B, Levin RM and Mannikarottu AS*
The effect of partial bladder outlet obstruction on carbonyl and nitrotyrosine distribution
in rabbit bladder Urology. 2007;70(6):1249-53.
( SCI; IF= 2.334; Urology & Nephrology 26/69)

13. Levin RM*, Juan YS, Whitbeck C, Perez-Martinez FC, Lin WY
The effect of Darifenacin on overactive bladders in female and male rabbits.
Int Urol Nephrol. 2008;40(2):303-9.
( SCI; IF= 1.567; Urology & Nephrology 40/69 )

14. Juan YS, Hydery T, Mannikarottu A, Kogan B, Schuler C, Leggett RE, Lin WY, Huang
CH, Levin RM*. Coenzyme Q10 protect against ischemia/reperfusion induced
biochemical and functional changes in rabbit urinary bladder.
Mol Cell Biochem. 2008;311(1-2):73-80.
( SCI; IF=2.168; Cell biology 122/177 )

15. Lin WY, Guven A, Juan YS, Neumann P, Whitbeck C, Chichester P, Kogan B,Levin RM, ,Mannikarottu AS*
Free Radical Damage as a Biomarker of Bladder Dysfunction after Partial Outlet
Obstruction and Reversal
BJU International. 2008;101(5):621-6.
( SCI; IF= 3.19; Urology & Nephrology 14/69 )

16. Lin WY, Mannikarottu AS, Chichester P, Guven A, Leggett R, Juan YS, Johnson A,
Neumann P, Juan YS, Whitbeck C, Kogan B, Levin RM*
Changes in the smooth muscle of the corpora cavernosum related to reversal of partial
bladder outlet obstruction in rabbits.
J Androl. 2008;29(2):164-71.
( SCI; IF=3.141; Andrology 2/5 )

17. Lin WY, Rehfuss A, Schuler C, Levin RM*
Effect of coenzyme Q10 and lipoic acid on the response of the rabbit urinary bladder to
repetitive stimulation and in vitro ischemia
Urology . 2008;72(1):214-9.
( SCI; IF= 2.334; Urology & Nephrology 26/69 )

18. Guven A, Lin WY, Neumann P, Kogan B, Levin RM*
Effect of age on the role of Rho-Kinase in short term partial bladder outlet obstruction.
Urology. 2008;71(3):541-5.
( SCI; IF= 2.334; Urology & Nephrology 26/69 )

19. Juan YS, Mannikarottu A, Kogan BA, Leggett RE, Whitbeck C, Chichester P, Lin WY,
Johnson A, Levin RM. *
The Effect of Low-Dose Estrogen Therapy on Ovariectomized Female Rabbit Bladder.
Urology. 2008;71(6):1209-13.
( SCI; IF= 2.334; Urology & Nephrology 26/69 )

20. Perez-Martinez FC, Mannikarottu A, Guven A, Chichester P, Juan YS, Lin WY, Levin
RM*
Expression of parathyroid-hormone- related protein in the partially obstructed rabbit
bladder.
Urol Int. 2008;81(1):82-6.
( SCI; IF= 0.924; Urology & Nephrology 57/69)

21. Lin WY, Mannikarottu A, Chichester P, Neuman P, Johnson A, Perez-Martinez FC, Levin RM*
The effect of chronic partial bladder outlet obstruction on corpus cavernosum smooth
muscle and RHO-Kinase in rabbits.
Neurourology and urodynamics. 2008;(27-28):826-831.
( SCI; IF= 2.903; Urology & Nephrology 17/69)

22. Lin WY, Radu F, Schuler C, Leggett RE, Mannikarottu A, Levin RM*
The effect of overiectomy and oestrogen therapy on the free fatty acid content , endogenous lipase
activity , and phospholipid content of the rabbit urinary bladder.
BJU International. 2008;(102):1209-1213.
( SCI; IF= 3.19; Urology & Nephrology14/69)

23. Juan YS, Mannikarottu A, Schuler C, Lin WY, Huang CH, Levin RM*
The immediate effect of nitric oxide on the rabbit bladder after ovariectomy
Nitric Oxide. 2008 Nov;19(3):289-94. Epub 2008 Jun 21
( SCI; IF= 3.384; Biochemistry & Molecular 111/286)

24. Lin WY, Li S, Leggett R, Strassner J, Sokol R, Schuler C, Juan YS, Javed Z, Kogan B, Levin RM, Mannikarottu A*
Estrogen administration attenuates bladder outlet obstrustion induced oxidative stress
in the female rabbit.
Neurourology and urodynamics. 2009;(28):95-100.
( SCI; IF= 2.903; Urology & Nephrology 17/69)

25. Perez-Martinez FC, Juan YS, Lin WY, Guven A, Mannikarottu A, Levin RM*
Expression of parathyroid hormone-related protein in the partially obstructed and reversed
rabbit bladder.
Int Urol Nephrol. 2009;41(3):505-11. Epub 2008 Nov 1.
( SCI; IF= 1.567; Urology & Nephrology 40/69)

26. Li S, Hydery T, Juan Y, Lin WY, Kogan B, Mannikarottu A, Leggett RE, Schuler C,
Levin RM*
The effect of 2- and 4-week ovariectomy on female rabbit urinary bladder function
Urology. 2009 Sep;74(3):691-6. Epub 2009 Jun 7
( SCI; IF= 2.334; Urology & Nephrology 26/69)

27. Lin WY, Wu CF, Chen CS
Partial Bladder Outlet Obstruction: Bladder Dysfunction and Related Issues in Animal
Studies
Urol Sci. 2010;21(2):70?74.

28. Lin WY, Mannikarottu A, Li S, Juan YS, Schuler C, Javed Z, Blaivas J, Levin RM*
Correlation of in vivo bladder blood flow measurements with tissue hypoxia
World J Urol. 2011;29(2):165-70. Epub 2009 Feb 4
( SCI; IF= 2.438; Urology & Nephrology 23/69)

29. Lin WY, Chih-Shou Chen, Shi-Bei Wu, Yi-Pai Lin, Robert M.Levin , Yau-Huei Wei
Oxidative stress biomarkers in urine and plasma of rabbits with partial bladder outlet obstruction
BJU Int. 2011 Jun;107(11):1839-43.
( SCI; IF=3.19 Urology & Nephrology14/69)

30. Lin WY, Chang PJ, Lin YP, Wu SB, Chen CS, Levin RM, Wei YH.
Increased penile expression of transforming growth factor and elevated systemic
oxidative stress in rabbits with chronic partial bladder outlet obstruction.
Int J Androl. 2011 Jun 22 , in press
( SCI; IF=3.601; Andrology 1/5 )

博士論文

Bladder Outlet Obstruction: Biomarkers and Effect on Systemic Oxidative Stress

國際學術研討會報告

1. Title: Preliminary Study of Electric Stimulation on Premature Ejaculation in Patients with
Chronic Pelvic Pain Syndrome or Chronic Prostatitis
Meeting Location: European Society for Sexual Medicine ( Denmark ),
Date: 2005
Oral/Poster: Oral

2. Title: Effect of Letrozole on Female Rabbit Urinary Bladder Function
Meeting Location: American Urology Association annual meeting (USA)
Date: 2007
Oral/Poster: modified poster

3. Title: Free radical damage as a biomarker of bladder dysfunction following partial outlet
obstruction and reversal
Meeting Location: American Urology Association annual meeting (AUA)
Date: 2007
Oral/Poster: Oral

4. Title: The Effect of Partial Outlet Obstruction on Corpus Cavernosum Smooth Muscle
and Rho-kinase in Rabbits
Meeting Location: Annual Meeting of the International Continence Society (France)
Date: 2007
Oral/Poster: Modified Poster

5. Title: Changes in the smooth muscle of the corpora cavernosum related to reversal of
partial bladder outlet obstruction in rabbits.
Meeting Location: Annual Meeting of the International Continence Society (France)
Date: 2007
Oral/Poster: Modified Poster

6. Title: The Effects of L-arginine and L-NAME on the Response to Chronic Partial Bladder
Outlet Obstruction in the Rabbit
Meeting Location: Annual Meeting of the International Continence Society (France)
Date: 2007
Oral/Poster: Modified Poster

7. Title: Changes in the smooth muscle of the corpora cavernosum related to reversal of
partial bladder outlet obstruction in rabbits.
Meeting Location: American Urology Association annual meeting (USA)
Date: 2008
Oral/Poster: Modified Poster

8. Title: The Effects of estrogen in female rabbit with Partial Bladder Outlet Obstruction
Meeting Location: American Urology Association annual meeting (USA)
Date: 2008
Oral/Poster: Modified Poster

9. Title: The expression of MMP-2, periostin, and CTGF in chronic partial bladder
outlet obstruction-induced fibrosis
Meeting Location: Pan-Pacific Continence Society (Korea)
Date: 2010
Oral/Poster: Modified Poster

10. Title: Reverse of bladder outlet obstruction attenuate systemic oxidative stress
Meeting Location: International Continence Society (England)
Date: 2011
Oral/Poster: Poster

專題研究計畫

1.國科會研究計畫
Research Subject: The effect of L-NAME and L-arginine of bladder and penile
function in rabbit with partial bladder outlet obstruction
Research Grant: National Scientific Council
Year: 2008~2010

Research Subject: Chronic partial bladder outlet obstruction-induced fibrosis and
related erectile dysfunction-pathological mechanism, biomarker and therapy
Research Grant: National Scientific Council
Year: 2010~2013

2.長庚研究計畫
Research Subject: The effects of nitric oxide on detrusor and corpous cavermosum
smooth muscle function in rabbits with 8 weeks partial bladder outlet obsturction
Research Grant: Chang Gung Medical Foundation
Year: 2008~2010

Research Subject: The pathophysiology of bladder failure secondary to chronic partial bladder outlet obstruction
Research Grant: Chang Gung Medical Foundation
Year: 2010~2011