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論文 |
| 1 |
Hsu Cheng-Ming(徐正明醫師), Chang Shun-Fu, Tsai Yao-Te, Tsai Ming-Shao, Chang Geng-He, Chen Hung-Chin, Huang Ping-Chung, Ko Chien-An, Wu Chin-Yuan, Lin Sheng-Fung* and Yang Ming-Yu* (2022). "Down-regulation of AMPD3 Is Associated With Poor Survival in Head and Neck Squamous Cell Carcinoma." In Vivo 36(2): 704.
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| 以流式細胞分析儀檢測單磷酸腺苷脫氨酶3(AMPD3)對人類頭頸部鱗狀細胞癌細胞(SCC-4、SCC-25、FaDu、Detroit 562)之細胞週期分佈(PI標定)的影響。
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| 2 |
Lee Chiang-Wen(李江文老師), Hsu Lee-Fen(許麗芬老師), Wu I. Lin, Wang Yung-Li, Chen Wei-Chen, Liu Yan-Jun, Yang Lu-Tang, Tan Chong-Lun, Luo Yueh-Hsia, Wang Chia-Ching, Chiu Hui-Wen, Yang Thomas Chung-Kuang, Lin Yen-Yue, Chang Hsin-An, Chiang Yao-Chang, Chen Ching-Hsiang, Lee Ming-Hsueh, Peng Kuo-Ti and Huang Cathy Chia-Yu* (2022). "Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice." Journal of Hazardous Materials 430: 128431.
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| 以共軛焦顯微鏡觀察小鼠海馬迴組織切片免疫螢光染色結果，研究經過情境恐懼實驗(contextual fear experiment)後，控制組與口服聚苯乙烯微塑膠(PS-MPs)的小鼠，其神經元活動指標Egr1及cFos蛋白表現的差異。
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| 3 |
Huang Cheng-Yi(黃政義醫師), Lee Ko-Chao, Tung Shui-Yi, Huang Wen-Shin, Teng Chih-Chuan, Lee Kam-Fai, Hsieh Meng-Chiao*(謝孟樵醫師) and Kuo Hsing-Chun*(郭星君老師) (2022) "2D-DIGE-MS Proteomics Approaches for Identification of Gelsolin and Peroxiredoxin 4 with Lymph Node Metastasis in Colorectal Cancer." Cancers 14 DOI: 10.3390/cancers14133189.
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| 人類大腸癌細胞(DLD-1)經分別搭載對照載體(scrambled-shRNA)、肌動素調節蛋白沉默載體(GSN-shRNA)、過氧化物還原酶4沉默載體(PRDX4-shRNA)的病毒顆粒轉染後抑制相關蛋白表達，再以流式細胞分析儀檢測其細胞週期分佈(PI標定)。
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| 4 |
Lin Chieh-Mo(林玠模醫師), Huang Tzu-Hsiung, Chi Miao-Ching, Guo Su-Er, Lee Chiang-Wen, Hwang Su-Lun and Shi Chung-Sheng*(石宗憲老師) (2022). "N-acetylcysteine alleviates fine particulate matter (PM2.5)-induced lung injury by attenuation of ROS-mediated recruitment of neutrophils and Ly6Chigh monocytes and lung inflammation." Ecotoxicology and Environmental Safety 239: 113632.
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| 以利用流式細胞分析儀檢測由微粒物(PM2.5)誘發肺損傷的小鼠模型所收集的肺部細胞中CD11b、F4/80、Ly6C的表達水平，以鑑定及量化嗜中性白血球(neutrophils)或單核細胞(monocytes)亞型。
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| 5 |
Chang Pei-Hung, Lee Chun-Hui, Wu Tyler Min-Hsien, Yeh Kun-Yun, Wang Hung-Ming, Huang Wen-Kuan, Chan Sheng-Chieh, Chou Wen-Chi, Kuan Feng-Che, Kuo Hsuan-Chih, Kuo Yung-Chia, Hu Ching-Chih and Hsieh Jason Chia-Hsun* (2022). "Association of early changes of circulating cancer stem-like cells with survival among patients with metastatic breast cancer." Therapeutic Advances in Medical Oncology 14: 17588359221110182.
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| 從化療後之轉移性乳腺癌患者的外周血分離PBMCs，利用磁珠套組去除表現CD45的細胞，再以流式細胞分析儀檢測循環腫瘤細胞CTCs (CD133-EpCAM+Hoechst+CD45−)及循環腫瘤幹細胞cCSCs (CD133+EpCAM+Hoechst+CD45−)之表達比例。
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| 6 |
Lin Yang-Hsiang, Liu Yu-Chin, Chen Cheng-Yi, Chi Hsiang-Cheng, Wu Meng-Han, Huang Po-Shuan, Chang Cheng-Chih, Lin Tzu-Kang, Yeh Chau-Ting* and Lin Kwang-Huei* (2022). "LPAL2 Suppresses Tumor Growth and Metastasis of Hepatocellular Carcinoma by Modulating MMP9 Expression." Cells 11(16): 2610.
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以流式細胞分選儀從人類肝癌細胞(HepG2、Huh7)中篩選出表達CD133-及CD133+的細胞後，再利用qRT-PCR檢測LPAL2 (lipoprotein(a) like 2)的表達水平。
人類肝癌細胞(HA22T、Huh7)經分別搭載對照載體(shLuc)及LPAL2沉默載體(shLPAL2)的病毒顆粒轉染後，再以流式細胞分析儀檢測其CD133的表達水平。。
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