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論文 |
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Lai Tsai-Chun, Chen Yu-Chen, Cheng Hui-Hua, Lee Tzu-Lin, Tsai Jaw-Shiun, Lee I. Ta, Peng Kuo-Ti, Lee Chiang-Wen*(李江文老師), Hsu Lee-Fen*(許麗芬老師) and Chen Yuh-Lien* (2022). "Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D." Particle and Fibre Toxicology 19(1): 25.
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| 以流式細胞分析儀檢測分別處理維生素 D(1,25(OH)2D3)、高濃度葡萄糖(HG)、顆粒物(PM 2.5 )之組合對人類臍靜脈內皮細胞 (HUVEC)的影響，包含分析細胞凋亡Annexin V表現、粒線體活性氧ROS濃度(MitoSOX Red標定)、細胞內活性氧ROS濃度(DHE標定、H2DCFDA標定)、粒線體膜電位變化(MitoStatus TMRE標定、JC-1標定)。
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| 2 |
Pan Po-Jung, Wang Jia-Chi, Tsai Chih-Chun and Kuo Hsing-Chun*(郭星君老師) (2022). "Identification of early response to hypertonic dextrose prolotherapy markers in knee osteoarthritis patients by an inflammation-related cytokine array." Journal of the Chinese Medical Association 85(4): 525-531.
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| 以流式細胞分析儀檢測骨關節炎(Osteoarthritis, OA)患者經高滲葡萄糖增殖療法治療前後的膝關節滑液中MMP2、TIMP-1、EGF、IL-10、IL-22等細胞激素蛋白濃度(搭配Cytokine Bead Array, CBA試劑組)。
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| 3 |
Hsu Chien-Yi, Vo Thi Thuy Tien, Lee Chiang-Wen, Chen Yuh-Lien, Lin Wei-Ning, Cheng Hsin-Chung, Vo Quang Canh and Lee I. Ta* (2022). "Carbon monoxide releasing molecule-2 attenuates angiotensin II-induced IL-6/Jak2/Stat3-associated inflammation by inhibiting NADPH oxidase- and mitochondria-derived ROS in human aortic smooth muscle cells." Biochemical Pharmacology 198: 114978.
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| 以流式細胞分析儀檢測預先處理一氧化碳釋放分子2 (CORM-2)，對後續處理血管緊張素II (Angiotensin II, Ang II)誘導的人類胸主動脈平滑肌細胞(HASMC)炎症反應的影響，包含分析細胞內活性氧ROS濃度(CellROX®Green標定)、粒線體活性氧ROS濃度(MitoSOX Red標定)。
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Chen Vincent Chin-Hung(陳錦宏醫師), Hsu Tsai-Ching, Lin Chiao-Fan, Huang Jing-Yu, Chen Yi-Lung*, Tzang Bor-Show* and Mcintyre Roger S. (2022). "Association of Risperidone With Gastric Cancer: Triangulation Method From Cell Study, Animal Study, and Cohort Study." Frontiers in Pharmacology 13.
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| 以流式細胞分析儀檢測處理不同濃度之抗精神病藥物利培酮(Risperidone)對胃癌細胞(KATO-III)的影響，包含分析細胞週期比例(PI標定)、細胞凋亡Annexin V表現。
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Tseng Tsui-Hwa, Wang Chau-Jong, Lee Yean-Jang, Shao Yi-Chia, Shen Chien-Heng, Lee Ko-Chao, Tung Shui-Yi*(董水義醫師) and Kuo Hsing-Chun*(郭星君老師) (2022). "Suppression of the Proliferation of Huh7 Hepatoma Cells Involving the Downregulation of Mutant p53 Protein and Inactivation of the STAT 3 Pathway with Ailanthoidol." International Journal of Molecular Sciences 23(9): 5102.
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| 以流式細胞分析儀檢測處理不同時間點或不同濃度之樗葉花椒醇(Ailanthoidol, ATD)對肝癌細胞(Huh7)的影響，包含分析細胞週期比例(PI標定)、細胞凋亡Annexin V表現。
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Lin Yu-Sheng(林祐賸醫師), Lip Gregory Y. H., Ho Wan-Chun, Shi Chung-Sheng, Lin Meng-Hung, Kuo Ting-Yu, Chung Chang-Min, Chang Shih-Tai, Chen Yung-Lung, Chen Huang-Chung, Lee Wei-Chieh and Chen Mien-Cheng* (2022). "Statins to prevent pacing-induced cardiomyopathy: Evidence from the bench applied to clinical studies." Heart Rhythm 19(6): 960-968.
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大鼠心室心肌細胞(SV-40)分別以降膽固醇藥物Atorvastatin、肝X受體活化劑(LXR agonist)、肝X受體拮抗劑(LXR antagonist)、LXR antagonist + Atorvastatin組合預先處理，再以起博器進行培養後，利用流式細胞分析儀檢測其脂質表現(Nile Red標定)。
通過共軛焦顯微鏡觀察大鼠心臟組織LV septum及LV free wall的WGA螢光染色結果，再利用影像分析量化比較起博器組與Atorvastatin藥物治療組的心肌細胞肥大情形。
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