Sexually Transmitted Diseases

Sexually transmitted diseases (STDs) are spreading rapidly. Although they are more common now than ever before, many people fail to understand how to prevent themselves from contracting an STD. Furthermore, many people do not recognize the early symptoms, or do not know how to get diagnosed and treated for such problems.

Parents often fail to discuss STDs with their children, because they are afraid of talking about sex. The information and education on STDs are limited in some school systems, although these diseases should be fully addressed in junior highs and high schools. The increased sexual promiscuity in the United States over the past 25 years has also helped the epidemic STDs grow. Having more than one sexual partner greatly increases the risk of contracting an STD. Although women now have many options for birth control, only the use of condoms, a barrier precaution, greatly reduces the risk of contracting disease.

Some of the most dangerous STDs, including syphilis and gonorrhea, may occur without symptoms. Sexually active persons can carry an STD from one relationship to the next, infecting their new partners, while remaining completely unaware of the presence of disease.

Although most types of STD can be cured with antibiotics, there can be long-term, serious consequences. Many viruses are incurable, and a growing number of STDs can cause infertility in women. The best protection against STDs is to prevent them from occurring and, when they do occur, to obtain treatment immediately.

 


Prevention

The surest way to avoid an STD is to avoid sex. Some women may find abstinence an undesirable option, however. Sexually active women should practice safe sex:

  • Limit your sexual partners.
  • Know your partner's sexual history.
  • Use condoms.

Practicing safe sex means being responsible for yourself as well as your partner. Safe sex can keep you from contracting one of the many types of STDs, including chlamydia, gonorrhea, herpes, syphilis, and genital warts. These types of STD are highly contagious and can be contracted easily. There is no vaccine that can prevent them. Practicing safe sex can also help protect against becoming infected with human immunodeficiency virus (HIV), which causes AIDS (see Chapter 20).

Other than abstinence, monogamy with an uninfected partner is the best way to avoid picking up an STD. Having several sexual partners greatly increases your risk for STDs. Ask your sexual partners if they have ever had an STD or if they are having sex with others.

The Female Condom

There is now a condom that women can use themselves rather than relying on their male sex partners. Called the female condom, it consists of two rings with a latex sheath between them. The closed end of the sheath is inserted into the vagina, and the ring is placed high up around the cervix. The open end of the sheath remains outside the uterus. (See Fig. 19.1)

Like the condom for men, female condoms can be bought in drugstores without a prescription. It should be used once and then thrown away. Used as directed, it can be effective in preventing STDs and pregnancy.

Condoms, when used properly, are the most effective method to keep an STD from spreading. A woman should insist that a male sexual partner wear a condom, even if she is using another form of birth control. This is also true for women who do not need birth control, such as those who have gone through menopause or who have had their uteruses removed. If a male sexual partner does not want to use a condom, there is now a condom that women can use (see "The Female Condom," below). Women must learn to refuse to have sex with a man unless a condom is used.

Condoms are readily available over the counter in most drug stores, and there are many kinds. Condoms made of natural materials do not keep some viruses from passing between you and your partner, so latex condoms should always be used. A spermicide used with a condom may offer additional protection.

You cannot catch most types of STDs from nonsexual contact, such as hugging or holding hands. Most STD organisms cannot survive outside the body for long, so catching an STD from sitting on a toilet seat is very unlikely.

In addition to taking steps to prevent getting or passing on an STD, it is important to recognize the symptoms of these diseases. The better a woman understands her body, the better prepared she is to recognize such symptoms.

Back to Top


Types of STDs

The following discussion covers the major types of STDs along with their symptoms, causes, diagnosis, and treatment. Some general guides apply to most STDs (see "General Management of STDs," below).

Chlamydia

Symptoms

Chlamydia often has no symptoms, and women are less likely to have symptoms than men. Signs of infection may only be noted during a doctor's physical examination. The type of symptoms depends on the type of chlamydia infection and the area it attacks. One of the most common signs in women is a creamy white discharge from the vagina.

When symptoms do occur, they usually appear 1 to 3 weeks after infection. Women usually report a thin vaginal discharge, abdominal pain, and burning during urination. Men often report a burning sensation during urination and a urethral exudate. Men are more likely to display symptoms, women usually learn that they are infected only when their male sexual partner begins to show signs of infection.

Chlamydia commonly results in a genitourinary infection, such as nongonococcal urethritis (NGU), which is marked by a thin penile discharge in men and mild vaginal discharge in women. Chlamydia can infect the cervix (the opening of the uterus) a condition called cervicitis. If the cervicitis is not treated, the infection can move up into the uterus and the fallopian tubes. Infection of the tubes can cause a dangerous condition called pelvic inflammatory disease (PID) which may result in infertility.

Men and women who have anal sex, can have chlamydia infections of the rectum (proctitis). Swelling and soreness of the lymph nodes and rectal bleeding are signs of infection.

Newborns who get chlamydia from their mothers develop pneumonia and eye infections. Chlamydia is the leading cause of blindness in babies born in developing countries.

Cause

Chlamydia infections are caused by the bacterium Chlamydia trachomatis . This infection is the most common STD in the United States, and can be spread through vaginal or anal sex. It often is transmitted along with gonorrhea and contributes to a condition called pelvic inflammatory disease (see "Pelvic Inflammatory Disease). A woman can pass chlamydia to her baby during its birth. In men chlamydia can cause such manifestations as epididymitis (infection around the testicle) and proctitis.

Diagnosis

Diagnosis of chlamydia is often difficult because it may have no symptoms. A woman may be tested if her partner has been found to be infected. Or she may be tested if she has symptoms, such as vaginitis or PID.

A sample of discharge can be taken from the vagina or the cervix and tested. A culture is the most accurate way to diagnose chlamydia.

Treatment

The antibiotics recommended for treatment of chlamydia are doxycycline or azithromycin. Doxycycline must be taken for 7 days, but azithromycin -- which is newer -- can be taken in one dose.

Pregnant women with chlamydia infection are advised to use erythromycin, since tetracycline can adversely affect the fetus.

All sex partners should be informed of the infection. They should be tested if possible, but if testing is not available, they should be treated for chlamydia infection even if they have no symptoms.

General Management of STDs

Some guidelines about STDs apply regardless of the type of disease. For the best results, follow these recommendations:

  • While taking antibiotics for an STD, complete the recommended treatment, even if symptoms go away before all the antibiotics have been taken. Stopping too soon can allow infection to return and prompt the bacterium or virus to develop resistance to the treatment.
  • Sex partners of persons with STDs should be tested and treated. Both partners should be given antibiotics at the same time. This keeps the partners from passing the infection between themselves.
  • To prevent reinfection, abstain from intercourse until all antibiotics have been taken and symptoms have diasppeared.
  • Use condoms to prevent reinfection.
  • Those who have one STD should probably be tested for others. Having one STD puts a person at a risk for others. In particular, gonorrhea and chlamydia commonly occur together. Diseases that cause open sores on the genitals increase the chance of getting AIDS from an infected partner.

Gonorrhea

Symptoms

Both men and women can contract gonorrhea. Women may have no symptoms; however, they usually occur and can include vaginal discharge and dysuric (painful urination). Women may delay treatment because they do not think the discharge is serious.

Men may have no symptoms for a 3- to 6-day period (called the incubation period). At the end of this time, they often develop a tingling sensation in the urethra followed by painful urination and a white discharge. With some strains of gonorrheal bacterium there may never be a discharge.

Symptoms vary, depending on the site infected. Men and women who have anal sex may have rectal discharge and discomfort; men and women who engage in oral sex may experience sore throat, pain on swallowing, cervical lymph nodes, and red tonsils with a discharge, often confused with strep throat. Women who have infection of the reproductive organs can have severe lower abdominal pain and fever. These signs may be the beginning of PID, a common cause of infertility in women. Infection of the fallopian tubes occurs in nearly 15 percent of the women who contract gonorrhea.

In its advanced stages, gonorrhea can enter the bloodstream and spread throughout the body, causing complications. It can attack the heart and joints, but these developments can be prevented through treatment.

Cause

Gonorrhea is caused by the bacterium Neisseria gonorrhoeae . It is second only to chlamydia in terms of number of cases in the United States. About 45 percent of people with gonorrhea also have chlamydia, and the risk factors of infection are similar. Even though the number of cases of gonorrhea seems to be dropping, about 1 million new cases are still reported each year. It is most common in people between the ages of 15 and 30. Babies born to mothers with the disease can contract an infection called gonococcal ophthalmia neonatorum at birth when they pass through the vagina. This condition can affect the baby's eyes, causing blindness, and requires a different antibiotic than that used to treat chlamydia infection in the newborn.

Diagnosis

Gonorrhea is diagnosed from a specimen taken from the infected area. A swab is used to take a sample of discharge from the urethra, cervix, rectum, or throat, depending on which areas were exposed. A sample will be cultured so that every involved area can be definitively diagnosed.

Treatment

Women with gonorrhea as well as their sex partners should be treated. Anyone with gonorrhea should avoid all sexual activity while under treatment, because the disease is very easily spread.

Many types of drugs are used to fight gonorrhea. Although once antibiotics such as penicillin and tetracycline were the mainstays of treatment, today a large percentage of gonorrhea bacteria are resistant to these drugs. Therefore, newer drugs like ceftriaxone are used. Because gonorrhea and chlamydia often occur together, doctors usually recommend that patients also take doxycycline to eliminate any undiagnosed chlamydia.

Pregnant women can be safely treated with ceftriaxone. In case they also have a chlamydial infection, they are usually treated with erythromycin as well.

In women with simple infections whose symptoms are cleared by treatment, further testing is not needed. However, women who continue to have symptoms should be tested to see if the bacteria persists, and if so, what types of antibiotics are likely to eliminate it.

Genital Warts

Symptoms

Genital warts begin as tiny red or pink bumps. After about 2 months (the incubation period can range from 1 to 6 months), they become moist on the surface. The warts will spread if left untreated. In males they are usually located on the scrotum or on the shaft or tip of the penis. In women they grow on the vulva, on the cervical and vaginal walls, and around the anus. The virus can also cause growths on the cervix.

Cause

Also called venereal warts or condyloma, genital warts are caused by the human papillomavirus (HPV). This virus causes warts on the skin of men and women and is easily transmitted by sexual contact. There are many different types of HPV that can cause warts. Some types have been linked to a risk of cervical cancer. (See Chapter 15.) Pregnant women, men and women with weak immune systems, and those with poor hygiene are more prone to contract the virus.

Diagnosis

Genital warts look similar to typical skin warts. A trained eye often can diagnose genital warts without any tests. Painting the area with a weak acid solution causes the warts to turn white, which can help in diagnosis. Warts on the cervix can be detected by a Pap test, in which a sample of cells is removed from the cervix for study under a microscope. A sample of the wart can be taken and studied to reveal what type of HPV is causing the infection.

Treatment

Genital warts are treated by removing the warts from both partners. Medications that are placed on the wart include a natural resin called podofilox (which inhibits wart growth) and acids such as trichloroacetic or bichloroacetic acid (which dry up the warts). Podofilox should not be used by pregnant women.

Other options include laser surgery and freezing the warts, called cryotherapy. Electrodesiccation (sending an electrical current through the tissue, which then dries up) is also used to remove the warts.

Although the visible warts can be removed, this does not cure the virus. As yet there is no cure or vaccine for HPV. Since the virus may remain in the body, warts may come back and require further treatment. Because of the risk of cancer, women who contract the virus should have frequent and regular Pap tests.

Pelvic Inflammatory Disease

When an STD moves from the vulva and vagina up to the uterus and fallopian tubes, it causes pelvic inflammatory disease (PID). PID can cause infertility in a woman even without symptoms.

Most cases of PID occur when Chlamydia trachomatis or Neisseria gonorrhoeae spreads up the fallopian tubes, but they can be caused by other STDs as well.

The use of an intrauterine device (IUD) for birth control can increase the risk of PID, with the greatest risk is coming a few months after the IUD is inserted. Women who develop PID after using an IUD are usually advised to have it removed.

A woman may have no symptoms of PID until its advanced stages. Then, it can cause abdominal and low back pain and fever. White blood cells, working to eliminate the infection, may cause a discharge.

PID is one of the major preventable causes of infertility in women. The infection in the fallopian tubes can cause abscesses and scar tissue to form in the tubes that may block sperm from passing through them, leaving the woman infertile. Approximately 13 percent of women who have one attack of PID are left infertile. Those who suffer three attacks of PID have a 75 percent chance of becoming infertile.

PID is diagnosed during a gynecological exam and lab testing for STDs. Although chlamydia and gonorrhea are commonly diagnosed as the causes of PID, these two types of bacteria can die quickly. They may not be present at the time testing is done. The common bacterium Escherichia coli, found in the digestive and genital tracts of healthy men and women, is often the only type of bacteria noted at the time of the diagnosis.

PID is treated with antibiotics that may be administered orally or intravenously, depending on the severity of the infection. In some cases, surgery is required to remove abscesses that remain after antibiotic treatment.

Genital Herpes

Symptoms

The symptoms of genital herpes first appear after a 3- to 7-day incubation period. Genital herpes is characterized by pain and itching in the genital area along with blisters or open sores. When these are present, a person is said to be having an outbreak. The first outbreak of genital herpes is usually marked by additional flulike symptoms, including fever, headache, and swollen lymph nodes in the groin area. Recurrent outbreaks tend to have more localized symptoms.

The symptoms are usually preceded by a tingly or burning sensation in the area, that will later develop into tiny red blisters in both men and women. These blisters then grow into larger pimplelike bumps that have a watery yellow center. The blisters rupture, and within 3 or 4 days a crust forms.

In both sexes, the blisters can appear in the genital area and on the thighs, abdomen, buttocks, and anus. In women blisters usually appear on the labia and around the clitoris. In men, they may appear on the penis and scrotum. Sometimes blisters near the opening of the urethra and on the tip of the penis will swell up, making urination difficult and painful.

Blisters may also develop internally on the female cervix and vaginal walls or inside the male urethra. These internal lesions may make it difficult for men to urinate and difficult to detect the virus in women.

The entire process of a herpes outbreak, from initial tingle to dried-up crust, can last about 3 weeks, but the virus may still be active -- and the infected person contagious -- for 2 weeks after the symptoms disappear. Although the virus is most contagious during the blistering stage, it can be transmitted during the early phase of burning and tingling as well.

Even though the symptoms subside, the virus moves to the nerve cells in the base of the spinal chord, where it is dormant. During a recurrent outbreak, the virus travels down the nerves to the genital area and causes a new set of blisters and more distress. Between 50 and 75 percent of those who have an initial outbreak will suffer a recurrent infection within 3 months. The cause of the recurrent attacks is unknown, but there does seem to be a correlation between outbreaks and stress or a weakened immune system.

There is no cure for genital herpes, but each successive outbreak has fewer and weaker symptoms. After a number of years, the outbreaks may disappear.

If a pregnant woman has open herpes lesions, she runs the risk of infecting her baby as it passes through the vagina at birth. If infected, the baby may suffer brain damage, blindness, or death if not treated. A pregnant woman with herpes will be examined when she is in labor. If she has active sores, she should have her baby by cesarean section.

Cause

About 150 million people in the United States are thought to have been exposed to herpes simplex virus, the virus that causes genital herpes. Each year, about 300,000 new cases are diagnosed. Herpes simplex virus type 2 causes about 80 percent of cases of genital herpes. The other 20 percent is caused by herpes simplex type 1 virus, better known as the cause of sores on the mouth and lips.

The virus is transmitted through sexual contact -- vaginal, anal, or oral -- and can also enter the body through mucous membranes or cuts in the skin. Genital herpes can also infect the eyes if fingers carrying the virus touch the eyes. Active genital herpes is highly contagious. Transmission is known to occur during inapparent activation of the infection, even when blisters or open sores are not visible.

Diagnosis

A diagnosis of genital herpes is made by taking a sample culture from a liquid-filled blister or a sore in its early phase.

Treatment

Genital herpes has no cure but a vaccine for prevention is being developed. Keeping the infected area clean and dry can help improve a person's comfort when having an outbreak. Use of the oral drug acyclovir can reduce the length of time the virus can be transmitted, shorten the healing time, and decrease the severity of symptoms. Pregnant women are best served by using the topical form. Persons who have frequent recurrences can take acyclovir daily to prevent attacks. Because the infection is usually contracted while sores are present, abstaining from sex until sores are completely healed can help stop the spread of herpes. Transmission, however, can occur during active disease without blisters or symptoms; therefore the safest approach is to use a condom.

Syphilis

Symptoms

Syphilis occurs in three stages: primary, secondary, and tertiary. The signs of primary syphilis are painless sores called chancres on the genitals, tongue, lips, breast, or rectum, along with swollen lymph nodes in the adjacent area. If the sore is located in a woman's vagina, it can easily go undetected. The incubation period for primary syphilis is 2 to 3 weeks and sometimes as long as 8 weeks.

Secondary syphilis begins in 2 to 6 weeks after the chancre heals, usually without treatment. The signs of secondary syphilis may include fever, headache, aching joints, and a skin rash. The skin rash appears diffusely as well as on the bottoms of feet and the palms of hands.

An infected person then can go through a period when syphilis is latent, that is without signs or symptoms. They may be followed by tertiary syphilis if the person is not treated. Latent syphillis can be life threatening because the bacteria by this time has spread throughout the body and into the blood system, and brain. Tertiary syphilis, which appears years later, can cause a number of problems, including nerve and brain damage and heart disease. These severe symptoms are not very common in the United States, since syphilis rarely progresses to this late stage.

Women infected with syphilis can pass the infection to their unborn fetus during pregnancy. About 50 percent of those fetuses infected will be born prematurely or stillborn. Those infants that do survive may appear healthy at birth but develop problems later.

Cause

Until the recent arrival of acquired immunodeficiency syndrome (AIDS), syphilis was the most serious of the STDs. It is caused by the bacterium Treponema pallidum . Although it was once a very common infection, today syphilis is rarer than chlamydia and gonorrhea. In the past few years, however, the incidence of syphilis has increased, especially within the homosexual community.

Syphilis is contracted during sexual contact, through cuts or sores in the skin or mucous membranes. The disease is very contagious. It can also pass through the blood and to an unborn fetus from an infected mother.

Diagnosis

Infection is suspected based on the presence of sores (for primary syphilis) or rash and flulike symptoms (for secondary syphilis). A positive blood test is necessary to diagnose syphilis. Even if a person has no symptoms, a blood test can usually detect syphilis.

Some states require syphilis tests before issuing marriage licenses, so some people learn only then that they have syphilis at that time. Others are tested for syphilis when they enter a hospital. Because of the danger of syphilis for the fetus, all pregnant women are tested for syphilis.

Treatment

Penicillin given intramuscularly is effective for primary and for secondary syphilis. Latent syphilis can also be treated with penicillin to prevent complications, but must be given longer and at higher doses to achieve success during this phase. Penicillin can be used safely to treat pregnant women and prevent transmission to their fetus. It can also be used to treat infected infants. Penicillin is the most commonly used antibiotic for syphilis, but doxycycline or tetracycline can be used for those who are allergic to penicillin.

Because syphilis can be spread when open lesions are present, sexual contact of any kind should be avoided during this time. Routine blood tests are required for one year following the initial syphilis infection to determine whether treatment has been successful.

Trichomonas

Symptoms

Common symptoms in women include an abundant yellow frothy musty smelling discharge. Sores may form on the cervix. The vulva may itch, and urinating may be painful. Most men with trichomonas infection do not have symptoms.

Trichomonas infection is caused by a small organism called Trichomonas vaginalis. It affects about 15 percent of sexually active women and 10 percent of sexually active men. It causes symptoms like those of vaginitis (see Chapter 15). Because the organism can live outside the vagina, nonsexual transmission may also occur.

Diagnosis

To diagnose trichomonas infection, a sample of the discharge is taken and examined under a microscope.

Treatment

Trichomonas infection is not usually serious and can be treated easily with metronidazole. Usually just one dose is needed, but some doctors choose to give a lower dose for 7 days. A woman and her sex partner(s) must be treated. They should avoid having sex until they have completed their treatment and no longer have symptoms. Anyone who is taking metronidazole should avoid drinking alcohol, which can cause severe nausea and vomiting when mixed with metronidazole.

Cytomegalovirus

Symptoms

CMV often has no symptoms. Women who do have symptoms may have a mild illness similar to the flu. Although CMV is not harmful for most women, it causes special concerns for a pregnant woman, who can pass CMV to her fetus through the umbilical cord. CMV is most risky if a woman first becomes infected while she is pregnant. If this happens, the fetus can be harmed. CMV can also be passed to the infant during birth and later through breast milk. Approximately 50 percent of mothers who have CMV pass it on to their infants, and of those infants 5 to 15 percent will have abnormal central nervous systems at birth.

Cause

Cytomegalovirus (CMV) is caused by a virus with the same name. Up to 70 percent of people have evidence in their blood that they have been infected with CMV. Children can contract the disease from an infected mother. One of the most common ways a woman gets CMV is by being exposed to children, for example, in day care. CMV also may be passed on through blood transfusions or through sexual activity with an infected partner.

Diagnosis

Cytomegalovirus is diagnosed through a blood test for CMV antibodies. Infection in the fetus can be diagnosed by testing blood or the amniotic fluid.

Treatment

There is no cure for CMV. Because a fetus can develop severe abnormalities if infected with the virus early in development, tests are performed early in pregnancy. Infection of the fetus late in pregnancy may lead to childhood hearing and learning problems.

Chancroid

Symptoms

The initial symptoms are one or more painful swellings (boils) that appear in the genital area. If ignored, these lesions will rupture and release pus.

Cause

Rare in the United States but common in the tropics, chancroid is caused by the organism Haemophilus ducreyi which is passed during sex across genital mucous membranes. It moves through the lymphatic system into the groin area to infect the glands.

Diagnosis

A microscopic examination of the pus is necessary to determine the cause of any lesions. Syphilis has similar symptoms, so this examination will rule out syphilis.

Treatment

Azithromycin, ceftriaxone, or erythromycin is most commonly given to treat the patient and prevent spread of the disease. Gentle pressure on the lesions can also help accelerate their healing. Even if they don't have symptoms, sex partners of women with chancroid should also be examined and treated.