Figure 3.
Sensitivity, Specificity, and Positive and Negative Predictive Values for the Papanicolaou Smear
for General Screening for Cervical Dysplasia in the English Language Medical Literature.
E.J. Mayeaux, Jr., M.D.
Associate Professor of Family Medicine
Clinical Associate Professor of Obstetrics and Gynecology
Louisiana State University Medical Center Shreveport, Louisiana
+ Pred. - Pred. Study
Study n Sens. Spec. Value Value Year Type
-----------------------------------------------------------------------------------------------
Studies of Pap smears in the general population.
Lozowski et al. (31) 155 96% 50% 84% ~~~ 1982 Cyto and Bx **
Soost et al. (33) 277842 80% 99.4% 73.4%-94.5% 99.8% 1991 Bx & Cyto x3
Studies of Pap smears in patients with previously low grade dysplastic Pap smears.
Kitchener et al. (19) 134 83.7% 66.7% 55.4% 89.2% 1987
Wheelock et al. (50) 273 76% 48% 58% 68% 1990 Cyto and Bx for prev. CIN1
Tabarra et al. (51) 76 66%-79% 80%-82% 95% - 97% 45%-49% 1992 2 Cytologists - cyto & Bx
Mayeaux et al. (24) 444 52% 71% 69% 54% 1993 Cyto and Bx for prev. CIN1
Studies of Pap smears in patients with previously atypical Pap smears.
Davis et al. (52) 236 36% 93% 55% 86% 1984
Jones et al. (18) 17% 98% 71% 78% 1986 Bx
Spitzed et al. (53) 18% 95% 83% 50% 1986 Bx
Pearlstone et al.(48) 1107 33% 98% 75% 87% 1990 BX
Controversies
and Decision Making for Uterine Cervical Disease
Colposcopy
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