Operational Obstetrics & Gynecology - 2nd Edition: The Health Care of Women in Military Settings

Normal Pregnancy

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Diagnosis of Pregnancy

Disability

Thermal Stress

Pregnancy Tests

Maternal Skin Changes

Noise

Prenatal Care

Nausea

Vibration

Nutrition

Heartburn

Solvents

Prenatal Vitamins

Sciatica

Heavy Metals

Laboratory Tests

Carpal Tunnel Syndrome

X-rays

Ultrasound Scans

URI

Radiation

Estimating Gestational Age

Antibiotics

CRT Exposure

Fetal Heart Beat

Other Drugs

Diving

Exercise

Immunizations

Hyperbaric Therapy

Aircrew Status

Diagnosis of Pregnancy

Pregnancy may be suspected in any sexually active woman, of childbearing age, whose menstrual period is delayed, particularly if combined with symptoms of early pregnancy, such as:

Early signs of pregnancy may include:

Pregnancy Tests

The diagnosis of pregnancy is accurately made with a urine pregnancy test. Current test kits are highly specific and detect 35-30 mIU of HCG (human chorionic gonadotropin, the pregnancy hormone) per ml of urine. In other words, the pregnancy test will be turning from negative to positive at about the time of the first missed menstrual period.

In the event of an "equivocal" pregnancy test...one that is not really positive nor negative, additional urine can be put through the test kit to boost the sensitivity. Instead of using 3 drops of urine, you can use up to 6 drops of urine. This will virtually double the sensitivity of the test, while increasing the chance of a false positive by only a small amount.

In an urgent situation, if a patient is unable to provide urine for the test, serum can be used in the urine test kit in place of urine.

This is an imperfect solution, because the forms of HCG (pregnancy hormone) found in serum are somewhat different from the forms found in urine. Further, the serum proteins tend to sludge up the test kit, both mechanically and biochemically. That said, using serum instead of urine will work well enough for most purposes in an operational setting and can provide immediate insight into the patient's problem.

Prenatal Care

At the first prenatal visit, take a careful history, looking for factors that might increase the risk for the pregnant woman. Many providers use a questionnaire, filled out by the patient, as a starting point for this evaluation. A sample Prenatal Registration and Obstetrical Questionnaire form can be used for this purpose.

One important aspect of prenatal care is education of the pregnant woman about her pregnancy, danger signs, things she should do and things she should not do. Many providers find it useful to give the woman printed material covering these issues that she can take with her. This allows her to read the material at a later time and to refer to it whenever she has questions. A sample Prenatal Information form can be printed and used.

Routine visits:

At each prenatal visit:

Check weight

Check blood pressure

Measure fundal height

Listen for the heartbeat

Check for edema

Check protein and glucose

Ask about fetal activity

Any new symptoms

Nutrition

A pregnant woman should eat a normal, balanced diet for one person.

This may prove difficult, particularly during the early part of the pregnancy when she may experience significant nausea.

It may also prove difficult later in pregnancy when she feels hungry all the time. These women may find they do better by having more frequent (but smaller) meals, or snacks between meals of relatively nutritious but low caloric foods.

Prenatal Vitamins

It is customary for pregnant women to take a prenatal vitamin each day.

In theory, it might be possible for a pregnant woman to obtain the right amount of essential vitamins and minerals through a careful and complete diet. In real life, it is difficult for most women to achieve such a diet, particularly the need for Folate. It is far simpler take a prenatal vitamin each day.

Those living in nutritionally-deprived areas will particularly benefit from the addition of prenatal vitamins to their diet.

Laboratory Tests

Some routine lab tests are done on all pregnant women at different times during the pregnancy. Other tests are done for a specific indication.

As early in pregnancy as feasible, obtain:

Subsequent lab tests consists of:

Other tests may be indicated, based on individual risk factors. These might include screening for Sickle Cell disease (or trait), thalassemia, G6PD, tuberculosis. Follow-up tests may also be needed, based on the original screen. For example, a woman found to be very anemic might be evaluated with serum folate and ferritin levels. A woman failing her glucose screening test will probably need a full glucose tolerance test.

Ultrasound Scan

Routine ultrasound scanning of all pregnant women early in pregnancy is recommended by some, but not all authorities in civilian settings.

For women in an operational environment, a routine ultrasound scan early in pregnancy can be very useful, because it identifies those destined to miscarry, those with an ectopic pregnancy, and those whose gestational age does not agree with their LMP.

Additional, medically-indicated ultrasound scans may also be appropriate. Ultrasound is used to evaluate vaginal  bleeding or pain, and discrepancies between the measured size of the uterus and the expected size. It may be used to look for multiple gestations, such as twins or triplets, determine the position of the fetus, and assess fetal growth. Later in pregnancy, it may be used to evaluate fetal well-being, amniotic fluid volumes, and to estimate fetal weight.

Estimating Gestational Age

The estimated delivery date is calculated by adding 280 days to the first day of the last menstrual period. An alternative method of determining the due date is to add 7 days to the LMP, subtract three months, and add one year. These calculations are made easier with the use of a Gestational Age Calculator.

One way to approximate a pregnancy's current gestational age is to use a tape measure to determine the distance from the pubic bone up over the top of the uterus to the very top. That distance, measured in centimeters, is approximately equal to the weeks of gestation, from about mid-pregnancy until nearly the end of pregnancy. This is known as MacDonald's Rule.

If a tape measure is unavailable, these rough guidelines can be used:

Ultrasound can be used to determine gestational age. Measurement of a crown-rump length during the first trimester (1-13 weeks) will give a gestational age that is usually accurate to within 3 days of the actual due date. During the second trimester (14-28 weeks), measurement of the biparietal diameter will accurately predict the due date within 10-14 days in most cases. In the third trimester, the accuracy of ultrasound in predicting the due date is less, with a plus or minus confidence range of as much as 3 weeks. A chart showing different ultrasound measurements at different gestational ages in shown in the Ultrasound Gestational Age Measurements chart.

Fetal Heart Beat

Although the fetal heart begins beating as early as the 5th week after the LMP, your ability to detect it will be limited by your equipment.

An ultrasound machine usually will see a heartbeat by 5 to 6 weeks gestation if equipped with a vaginal probe. Abdominal ultrasound will usually see the heartbeat by the 7th-8th week of pregnancy.

If you use a Doppler ultrasound fetal heartbeat detector, you can, with effort, usually hear the heartbeat by 12-14 weeks gestation and routinely after that.

Using a DeLee stethoscope (equipped with a head-mount), you can sometimes hear the heartbeat by 16 weeks but unless you are practiced with it, you won't hear it until 20 weeks, at which time the mother can usually tell you that she feels the baby moving.

Using a conventional stethoscope, you may never hear the fetal heartbeat.

Disability

Pregnancy causes many changes in women, not the least of which are change in weight and its' distribution, balance and increased vulnerability of ligaments and joints to stress. Because of these changes, the safe care of pregnant women requires that their normal work activities be modified. In the Navy, OPNAVINST 6000.1A is the instruction which provides the greatest detail of guidance for the administrative aspects of managing this disability. In the Marine Corps, MCO 5000.12d gives equivalent guidance.

Maternal Skin Changes

Over time, there is a darkening of the maternal skin, in predictable ways.

Exercise in Pregnancy

If the pregnancy is normal, moderate amounts of exercise are acceptable and desirable.

Some restrictions are appropriate:

1. Women should not start a new sport or exercise while pregnant, but may continue previous activities.

2. Activities which require a fine sense of balance to preserve the woman's personal safety (horseback riding, downhill skiing, etc.) are inadvisable  because pregnant women are inherently and unavoidably unstable in their balance.

3. Because of pregnancy-induced changes in the supporting cartilage and ligaments (softening), the joints are relatively unstable. Thus, activities which place great stress on any joints are unwise.

Nausea & Vomiting

These are common during pregnancy but may be aggravated by strong smells (food, garbage, machine oil, etc.) and motion. Symptoms appear quite early and are usually mild, requiring no treatment, disappearing by the 16th week or sooner. Occasionally, these symptoms are severe and require intervention.

If a pregnant woman states, "I can't keep anything down," and has ketones in her urine, she must be re-hydrated with crystalloid such as 5% dextrose in lactated Ringer's solution (D5LR). One liter is given in a short time (15-20 minutes), and the second liter given over an hour or two. Sometimes a third liter, given over several hours, will be necessary. While this rate of hydration would be much too fast for an older individual with heart disease, the cardiovascular system of a young, healthy, pregnant woman is very "stretchy" and will tolerate such rapid infusions well.

After IV therapy, the woman is generally feeling much better and can return to her duties. If this rehydration is insufficient to suppress her symptoms, then a more prolonged course of therapy is recommended.

Try to avoid antiemetics in the pregnant patient as the long-term consequences of most of the drugs on a developing pregnancy are not well established. Nonetheless, the long-term results of protracted vomiting, dehydration, electrolyte imbalance and ketosis are known and unfavorable to the pregnancy, so if it appears that IV hydration alone is not controlling the symptoms, move to antiemetics with dispatch.

Conventional doses of Antihistamines (Benadryl), Anticholinergics (Scopolamine), Compazine, Phenergan, and others have all been used to good advantage in these situations.

Heartburn

This common pregnancy-related ailment is caused by leaking of stomach acid into an unprotected esophagus, causing a chemical burn known as heartburn. The best relief is obtained by sucking on an antacid tablet until the pain goes away (one or two tablets).

Chewing and swallowing the tablets will also be effective but usually requires more tablets. If antacids are not available, eating or drinking anything will give some relief as it will partially buffer the acid in the esophagus and rinse it back down into the stomach.

Pepcid AC can also be used safely during pregnancy.

Sciatica

Sciatica occurs in 30% of pregnant women and is characterized by sharp pains in the hip and buttock on one or both sides, shooting down the back of the thigh. There may also be numbness of the anterior thigh on the effected side. This is due to compression of the sciatic nerve as it exits the spinal column in the small of the back. It is provoked by pregnancy and disappears after delivery.

Treatment of sciatica:

Sleeping with one leg straight and the other knee drawn up is a bad position as far as the back is concerned. Torsion is placed on the lower spine, aggravating any pressure on the sciatic nerve that may be present.

Sleeping on the side while pregnant is a good, idea, but both knees should be drawn up (flexing the thighs). Either side will work well.

In order to maintain this semi-fetal position comfortably, it is necessary to place a small pillow, folded blanket or towel between the patient's knees. This will absorb moisture, separate the legs, minimizing skin-to-skin contact, and provide additional support to the legs. With practice, this position will become very comfortable.

Carpal Tunnel Syndrome

Approximately 30% of pregnant women will develop numbness in one or both hands following the distribution of the median nerve. (index finger, middle finger, medial surface of ring finger, with sparing of the lateral surface of the ring finger and the little finger).

 

 

This is due to swelling and compression of the median nerve as it passes through the "carpal tunnel" in the wrist.

The dominant hand is more frequently effected. It is usually worse in the morning and improved in the evening. After delivery, the condition goes away gradually.

No treatment is necessary for this condition, so long as the motor portion of the nerve is still functioning normally. When treatment is necessary, splinting the wrist in a "cockup splint" will be helpful. Injection of the carpal tunnel with steroids may also be done (after 24 weeks of pregnancy).

Rarely, surgery may be necessary to free up the median nerve, although this is almost never required during pregnancy.

Upper Respiratory Infections

Most pregnant women will have at least one URI while pregnant.

Drugs are to be avoided, but the following medications may be used to good advantage if necessary:

Acetaminophen

 

This will effectively relieve muscle aches and fever. It is considered safe during pregnancy. (Category B drug, the same as prenatal vitamins.)

Guaifenesin

 

This expectorant is considered safe during pregnancy.

Pseudoephedrine

 

This sympathomimetic is a very effective decongestant. It's use during the 1st trimester is sometimes restricted because of indirect data suggesting a slight increased risk of fetal malformations. Late in the third trimester, its' use is again restricted because of its' somewhat unpredictable cardiovascular effects.

Triprolidine

An effective antihistamine, it is considered safe during pregnancy.

Antibiotics during Pregnancy

Because of various infections, the need to place pregnant women on antibiotics may arise. While this listing is necessarily incomplete due to space considerations, it will give you a guide to selecting antibiotics for these women.

Penicillins

Safe during pregnancy.

Cephalosporins

Safe during pregnancy.

Erythromycin

Safe during pregnancy.

Azithromycin

Safe during pregnancy.

Tetracycline(incl. doxy)

UNSAFE AT ANY TIME DURING PREGNANCY.

Metronidazole

Safe after 14 weeks. Avoid single-dose therapy. Safety prior to 14 weeks not well-established.

Aminoglycosides

Basically safe during pregnancy, but renal and ototoxicity are potential problems if the dose is high or prolonged.

Clindamycin

Safe during pregnancy.

Chloramphenicol

Probably safe prior to 28 weeks

Sulfa drugs

Safe prior to 34 weeks. After that, babies may develop jaundice if exposed to sulfa.

Quinine

Only to be used in life-threatening, chloroquine-resistant P. Falciparum infections

Miconazole

Safe during pregnancy.

Clotrimazole

Safe during pregnancy.

Quinacrine

Probably safe during pregnancy.

Chloroquine

With prolonged or high doses may cause congenital defects.

Pyrimethamine

Safe after 1st trimester. Add folic acid supplement.

Trimethoprim

Safe after 1st trimester. Add folic acid supplement.

Primaquine

May cause hemolytic anemia in the presence of G6PD deficiency. You may use it if needed.

 

Other Drugs during Pregnancy

Local anesthetics (Xylocaine) may be used with safety, although the addition of epinephrine to them is problematic. Epinephrine may have unpredictable effects on the maternal cardiovascular system (and hence the blood flow to the baby), so epinephrine is generally to be avoided.

Aspirin should not be taken as it may lead to significant fetal hemorrhage.

Codeine, Demerol, Morphine and other narcotics may be used as needed at any stage of pregnancy, but the addictive potential should be recognized. Other than the risk of fetal drug withdrawal syndrome, these major pain relievers are considered safe for use during pregnancy.

Immunization during Pregnancy

Tetanus Booster

Safe during pregnancy.

Diphtheria Toxoid

Safe during pregnancy.

Hepatitis B vaccine

May be safely given to pregnant women who are at high risk of exposure.

Influenza or pneumococcal immunization

May be given to pregnant women if they are at increased risk of these conditions.

Measles, mumps and rubella vaccine

Do not give to a woman while pregnant but defer until after the pregnancy.

Yellow Fever

Can and should be given to pregnant women traveling to areas where Yellow Fever endemic.

Polio

Can and should be given to pregnant women traveling to areas where polio is endemic.

Anthrax Immunization

Do not administer during pregnancy.

Immune globulin

May be given any time it is clinically indicated.

Thermal Stress

Fetal enzyme systems may not function properly if subjected to unusually high temperatures. In laboratory animals, elevation of core temperature is associated with fetal losses. For this reason, pregnant women are generally restricted from saunas and Jacuzzis.

The important thing to avoid is elevation of the core temperature. Any activity which may lead to an elevation of core temperature should be restricted. This would include sedentary exposure to high ambient temperatures which would otherwise be tolerated by a non-pregnant person, or moderate exercise in moderately-elevated temperatures.

Aboard warships, high ambient temperatures are often found in the:

Noise

Pregnant women should wear hearing protection when exposed to ambient noise levels above 84dBA, including infrequent impact noise. (So should non-pregnant women and men.)

Brief exposure (5 minutes per hour or less) of hearing-protected pregnant women to ambient noise above 84dBA in order to transit high noise areas is probably safe. Prolonged exposure to this level of noise is not recommended.

Pregnant women should avoid any exposure to ambient noise greater than 104dBA (corresponding to the need for double hearing protection), unless absolutely essential for quickly moving through a high noise area. The abdominal wall muffles (attenuates) the noise only somewhat and these very noisy areas may pose significant problems for the developing fetus.

Low-Frequency Whole Body Vibration

This is the type of shaking vibration one might experience if operating a jackhammer or driving at high speed over a highway with many potholes. It is to be avoided during pregnancy.

Chemical Solvents

Organic solvents, such as turpentine, fuel, oils, lubricants, and paint thinner may have adverse effects on a developing fetus.

The greatest risk comes from ingestion of these solvents, or by chemical spills with contamination of the skin. Inhalation, though less likely to delivery significant quantities of the material, should also be avoided.

Heavy Metals

It is very important to avoid maternal exposure to lead, cadmium and mercury.

X-rays during Pregnancy

All things being equal (which they never are), it is better to avoid x-rays while pregnant.

If indicated, (chronic cough, possible fracture, etc.), then x-rays are acceptable.

If you need an x-ray for a pregnant patient, go ahead and get it, but try to shield the baby with a lead apron to minimize the fetal exposure.

In your zeal to shield the pregnant abdomen, be careful not to shield so much that the value of the x-ray is diminished. If the shielding is too high while obtaining a chest x-ray, you will have to obtain a second x-ray to visualize the area shielded during the first x-ray.

Radiation exposure during Pregnancy

There appears to be a threshold for fetal malformation or death of at least 10 Rads, below which, biologic effects cannot be demonstrated. Allowing for a 10-fold margin of safety, it does not appear that any exposure below 1 Rad will have any harmful effects.

It would take about a thousand chest x-rays to deliver this amount of radiation to the unshielded maternal pelvis. 

At the same time, our knowledge of the biologic effects or radiation may be incomplete, so it is better for pregnant women, as a rule, to avoid any unnecessary exposure to ionizing radiation, and to use appropriate shielding when it is necessary.

CRT Use and Pregnancy

There is no good evidence that working in front of a CRT (Cathode Ray Tube) poses any threat for the pregnant woman, either from electromagnetic radiation (EMR) or from eyestrain.

Ergonomics are important for all sitting personnel, and particularly pregnant women. Good low back support, correct height for the CRT, wrist support and proper positioning of the legs (with the thighs flexed slightly so the knees are at least level with the hips, if not slightly higher than the hips), will contribute to the comfort and performance of these personnel.

Diving while Pregnant

Simply stated, pregnant women should not dive. It poses health risks to themselves and their fetus.

Pregnant women have increased amounts of body fat and 3rd-space fluid retention, each of which tends to trap nitrogen and other gasses due to poor circulation through those areas. This predisposes them to decompression sickness and air embolism.

While fetuses do not form gas bubbles more easily than women, even a few bubbles are likely to be very dangerous to the fetus because of fetal circulation. In adults, bubbles tend to be filtered by the pulmonary circulation through the lungs, but in fetuses, there is a bypass of the lung circulation through the foramen ovale and ductus arteriosus. This means that bubbles will not be filtered but may instead go directly to the brain or coronary vessels, possibly causing stroke or death.

There is also evidence that diving may produce birth defects, including limb reductions, cardiac malformations, and other problems, although this area has not been carefully researched.

Hyperbaric treatment

The effects of controlled hyperbarism on pregnant women and fetal development are uncertain.

In eastern Europe, scientists using relatively low pressures but repeatedly and for long periods of time have reported no particular problems with it. One study suggests that while in a hyperbaric atmosphere, the fetus changes its' circulatory flow in the direction of neonatal flow patterns (with narrowed or closed ductus arteriosus and foramen ovale). Upon return to normal barostatus, the flow again reverses to the normal fetal flow pattern. Whether this change poses any long-term problems for the fetus is unknown.

Based on these concerns, it is inadvisable to allow any pregnant woman to dive or enter a hyperbaric chamber unless strongly indicated for medical reasons. If an accident occurs in which it would be desirable to place the pregnant woman in a hyperbaric chamber, the risks to the fetus (mainly theoretical) must be balanced against the risks to the mother of not undergoing hyperbaric treatment.

Pregnant Aircrew Members

Aircrew status while pregnant is a complex issue, involving fetal risks, maternal risks and aircrew performance.

The maternal risks include decreased balance, decreased motion tolerance, decreased g-tolerance, gas compression/recompression effects. During the second and third trimester, placental abruption caused by the shearing force of inadvertently falling or striking the abdomen violently is a relatively common occurrence.

Fetal risks include exposure to noise, heat, chemicals, organic solvents, and low-frequency, whole-body vibration.

For these reasons, there is general agreement among the services to restrict pregnant aircrewman from participating in high-performance aircraft flights. There is less agreement in the area of helicopters and multiengine, fixed-wing aircraft.

Whether to allow a pregnant aircrewmember to continue her flight duties should be individualized, after considering the stage of pregnancy, the presence or absence of risk factors for her pregnancy or her flight crew performance, her individual service's rules, the degree of exposure to potentially harmful stressors in the aviation environment.