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賴啟智喉科現職：高雄長庚耳鼻喉科部助理教授級主治醫師教育部部定講師高雄長庚醫院癌症中心專科醫師高雄長庚兒童醫院耳鼻喉科部主治醫師鳳山醫院耳鼻喉科主治醫師學經歷：中山醫學大學醫學系醫學士高雄長庚醫院耳鼻喉科住院醫師高雄長庚醫院耳鼻喉科總醫師嘉義長庚醫院耳鼻喉科主治醫師廈門長庚醫院耳鼻喉科主治醫師屏東國仁醫院駐診主治醫師長庚大學臨床醫學研究所細胞生物學碩士學分班樹德科技大學兼任講師嘉義長庚科技大學兼任講師美國賓州匹茲堡大學醫學中心(UPMC): 頭頸癌(Head and Neck Oncological Surgery)、嗓音中心(Voice Disorders) 及吞嚥中心(Speech and Swallowing Disorders)臨床研究暨國際訪問學者 (20160301~20160831) 105年度(106年選)優良教學成效教師國外短期進修: 香港中文大學(The Chinese University of Hong Kong，CUHK) 威爾斯親王醫院(Prince of Wales Hospital) -- 顳骨手術進修 (200709) 美國哈佛醫學院附屬麻州總醫院(Massachusetts general hospital, MGH) -- 頭頸癌課程進修 (201004) 學會及期刊：台灣耳鼻喉頭頸外科醫學會專科醫師美國耳鼻喉頭頸外科學院(AAOHNS)會員醫師美國國家外科學院院士(FACS) 台灣頭頸部腫瘤醫學會專科醫師台灣音聲醫學會專科醫師亞洲頭頸部腫瘤醫學會醫師醫學期刊 Invited Reviewer: BMC Cancer (SCI, IF:3.265); BioMed Research International (SCI, IF:2.583) 論文及著作： 1. Publications: First author International Publication: 1. Lai CC, Friedman M, Lin HC, Wang PC, Hwang MS, Hsu CM, Lin MC, Chin CH. Clinical Predictors of Effective Continuous Positive Airway Pressure in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome. Laryngoscope. 2015; 125(8): 1983-1987.（SCI；IF=2.144；Otorhinolaryngology 7/43） 2. Lai CC, Lin PM, Lin SF, Hsu CS, Lin HC, Hu ML, Hsu CM, Yang MY. Altered expression of SIRT gene family in head and neck squamous cell carcinoma. Tumour Biology 2013;34: 1847-1854.（SCI；IF=2.84；Oncology 93/202） 3. Lai CC, Friedman M, Lin HC, Wang PC, Hsu CM, Yalamanchali S, Lin MC, Chen YC. Objective versus Subjective Measurements of Palatine Tonsil Size in Adult Patients with Obstructive Sleep Apnea/Hypopnea Syndrome. Eur Arch Otorhinolaryngol 2014; 271(8):2305-2310.（SCI；IF=1.545；Otorhinolaryngology 13/43） 4. Lai CC, Su CY, Free mucosa graft from the lateral tongue for reconstruction of intraoral buccal/lip mucosal defects after tumor resection. Laryngoscope 2007; 117(8): 1368-1372.（SCI；IF=1.801；Otorhinolaryngology 5/30） 5. Lai CC, Lin PW, Lin HC, Friedman M, Chang HW, Salapatas AM, Lin MC, Wang PC. Clinical Predictors of Pediatric Obstructive Sleep Apnea Syndrome. Ann Otol Rhinol Laryngol 2018; 127(9): 608–613.（SCI；IF=1.384；Otorhinolaryngology 21/42） 6. Lai CC, Lin PW, Lin HC, Friedman M, Chang HW, Salapatas AM, Lin MC, Huang KT. Effects of Upper Airway Surgery on Daytime Sleepiness in Nonobese Patients with Obstructive Sleep Apnea/Hypopnea Syndrome. Ann Otol Rhinol Laryngol 2018;127(12): 912-918.（SCI；IF=1.384；Otorhinolaryngology 21/42） Co-author International Publication: 1. Su CY, Lai CC, Wu PY, Huang HH. Transoral laser ventricular fold resection and thyroarytenoid myoneurectomy for adductor spasmodic dysphonia: long-term outcome. Laryngoscope 2010; 120(2): 313-318.（SCI；IF=2.1；Otorhinolaryngology 6/41） 2. Hsu CM, Lin PM, Lai CC, Lin HS, Lin SF, Yang MY. PER1 and CLOCK: Potential circulating biomarkers for head and neck squamous cell carcinoma. Head Neck 2014; 36(7):1018-26.（SCI；IF=2.641；Otorhinolaryngology 4/43） 3. Lin HC, Friedman M, Chang HW, Lai CC, Chin CH, Lin MC, Pott T, Samuelson C. Effects of Pillar implants for sleep-related breathing disorders on middle ear function. Eur Arch Otorhinolaryngol 2013; 270(8):2339-2343.（SCI；IF=1.608；Otorhinolaryngology 13/43） 4. Lu CT, Hsu CM, Lin PM, Lai CC, Lin HC, Yang CH, Hsiao HH, Liu YC, Lin HY, Lin SF, Yang MY. The Potential of SIRT6 and SIRT7 as Circulating Markers for Head and Neck Squamous Cell Carcinoma. Anticancer Res 2014 Dec;34(12):7137-7143.（SCI；IF=1.826；Oncology 145/202） 5. Hsu CM, Hsu CH, Yang MY, Lin HC, Lai CC, Hsu CY, Tsou YA. Glottal insufficiency with thyroid cartilage implantation: Our experience in eight patients. Clinical Otolaryngology 2012; 37(5):399-405.（SCI；IF=1.869；Otorhinolaryngology 9/43） 6. Li SH, Lin WC, Huang TL, Chen CH, Chiu TJ, Fang FM, Huang WT, Hsu CM, Luo SD, Lai CC, Su YY, Chuang HC, Chien CY. Significance of mTOR in patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil. Head Neck 2015; 38 Suppl 1:E844-52.（SCI；IF=2.641；Otorhinolaryngology 4/43） 7. Su YY, Chien CY, Luo SD, Huang TL, Lin WC, Fang FM, Chiu TJ, Chen YH, Lai CC, Hsu CM, Li SH. Betel nut chewing history is an independent prognosticator for smoking patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil. World J Surg Oncol. 2016;14:86.（SCI；IF=1.6；Surgery 107/197） 8. Hsu CM, Lin PM, Lin HC, Lai CC, Yang CH, Lin SF, Yang MY. Altered Expression of Imprinted Genes in Squamous Cell Carcinoma of the Head and Neck. Anticancer Res. 2016 ;36(5):2251-8.（SCI；IF=1.937；Oncology 156/195） 9. Chou FF, Hsu CM, Lai CC, Chan YC, Chi SY. Bilateral vocal cord palsy after total thyroidectomy–A new treatment–Case reports. Int J Surg Case Rep. 2017; 38: 32–36. 217/372. 10. Lin HC, Lai CC, Lin PW, Friedman M, Salapatas AM, Chang HW, Lin MC, Chin CH. Clinical Prediction Model for Obstructive Sleep Apnea among Adult Patients with Habitual Snoring. Otolaryngol Head Neck Surg. 2019;161(1):178-185.（SCI；IF=2.310；Otorhinolaryngology 13/42） 11. Huang HH, Fang FM, Yang LN, Yang CH, Lai CC, Hwang CF*. A Longitudinal Hearing Analysis in Nasopharyngeal Carcinoma Patients with Middle Ear Effusion. J Taiwan Otoloaryngol Head Neck Surg Vol. 48, No.4, 2013 (臺灣耳鼻喉頭頸外科雜誌48卷4期2013) 258-264. 1. Presentations: Oral presentations: a. Free mucosa graft of the tongue for reconstruction of buccal mucosa defect after resection of early buccal tumor. 77th meeting of TOHNS, 2004, Taipei b. Surgical Technique and Outcome of Transoral CO2 Laser Treatment for Reinke’s Edema of Vocal Folds. 78th meeting of TOHNS, 2005, Kaoshiung c. Transoral Laser Follicle Ablation for Hirsute Free Flaps in Oro-pharyngeal Reconstruction. 81th meeting of TOHNS, 2006, Taipei d. Is It Possible to Cure the Adductor Spasmodic Dysphonia Using Laser Myoneurectomy of Thyroartenoid Muscles? 86th meeting of TOHNS, 2009, Kaoshiung e. Objective vs Subjective Measurements of Palatine Tonsil Size in Patients with OSAHS. 89th meeting of TOHNS, 2010, Taipei f. Optimal Predictor for Desaturation in Drug-induced Sleep Endoscopy. 93th meeting of TOHNS, 2012, Taipei g. Minimally Invasive Single-Stage Multilevel Surgery for the Treatment of Obstructive Sleep Apnea/Hypopnea Syndrome. 97th meeting of TOHNS, 2014, Taipei h. Midline Nasal Rosai–Dorfman Disease with Nasal Bone and Nasal Septal Involvement Undergoing Total Resection and Staged Reconstruction– Case Report and Literature Review. 13th Asia-Oceania ORL-HNS Congress, 2015, Taipei i. Effect of Upper Airway Surgery in Non-obese Patients with OSA on Daytime Sleepiness. 101th meeting of TOHNS, 2016, Taoyuan Poster presentations: a. Epithelial-myoepithelial carcinoma of the parotid gland: a case report. 75th meeting of TOHNS, 2003, Tainan b. Free Mucosa Graft from the Lateral Tongue for Reconstruction of Buccal Mucosa Defect Following Tumor Resection. (poster) XⅧ International Federation of Otorhinolaryngological Societies (IFOS) World Congress, Rome, Italy, June 25-30, 2005. c. A huge carotid artery pseudoaneurysm after incision and drainage of deep neck infection - Case report. 89th meeting of TOHNS, 2010, Taipei d. Juvenile Xanthogranuloma (JXG) with Systemic Involvement—Case Report. 93th meeting of TOHNS, 2012, Taipei e. Longitudinal Analysis of Hearing Status in Nasopharyngeal Carcinoma Patients with Middle Ear Effusion. (IFOS 2013) 20th World Congress of the International Federation of Oto-Rhino-Laryngological Societies, Korea f. Rhabdomyolysis-related deep neck infection. 95th meeting of TOHNS, 2013, Taipei g. Dedifferentiated Carcinoma of the Supraglottis—Case Report. 102th meeting of TOHNS, 2017, Taitung h. Pharyngeal extranodal nasal-type natural killer/T-cell lymphoma – Case Report and Literature Review. 103th meeting of TOHNS, 2017, Kaohsiung i. Nasopharyngeal Papillary Adenocarcinoma – Case Report. 103th meeting of TOHNS, 2017, Kaohsiung; 14th Taiwan-Japan Conference, 2017, Kaohsiung j. Computed Tomography-Guided Hook Wire Localization for Removal of Deep Neck Impacted Foreign Body—Case Report 105th meeting of TOHNS, 2018, Taipei Research Project： (1)「利用舌黏膜自由移植瓣重建口頰或唇黏膜腫瘤切除後之缺損」的前瞻性研究, 協同主持人, CMRPG860371, 2007/10/01至2008/09/30 (2)「以二氧化碳雷射毛囊汽化術治療口–咽部重建後之多毛自由皮瓣」的前瞻性研究, 協同主持人, 2008/10/01至2009/09/30 (3)「阻塞性睡眠呼吸中止症與平衡及前庭功能的相關性」的前瞻性研究, 主持人, CMRPG8D1261-1262, 2015/01/01至2017/10/31 (4)「闡述動力相關蛋白1在頭頸部鳞狀細胞癌癌化過程中所扮演的角色」的前瞻性研究, 協同主持人, (5)「迴旋神經完整下，呼吸功能、發聲及吞嚥症狀在次發性副甲狀腺機能亢進病人手術切除後的變化」的前瞻性研究, 協同主持人

賴啟智喉科

現職：

高雄長庚耳鼻喉科部助理教授級主治醫師
教育部部定講師
高雄長庚醫院癌症中心專科醫師
高雄長庚兒童醫院耳鼻喉科部主治醫師
鳳山醫院耳鼻喉科主治醫師

學經歷：

中山醫學大學醫學系醫學士
高雄長庚醫院耳鼻喉科住院醫師
高雄長庚醫院耳鼻喉科總醫師
嘉義長庚醫院耳鼻喉科主治醫師
廈門長庚醫院耳鼻喉科主治醫師
屏東國仁醫院駐診主治醫師
長庚大學臨床醫學研究所細胞生物學碩士學分班
樹德科技大學兼任講師
嘉義長庚科技大學兼任講師
美國賓州匹茲堡大學醫學中心(UPMC): 頭頸癌(Head and Neck Oncological Surgery)、嗓音中心(Voice Disorders) 及吞嚥中心(Speech and Swallowing Disorders)臨床研究暨國際訪問學者 (20160301~20160831)
105年度(106年選)優良教學成效教師

國外短期進修:
香港中文大學(The Chinese University of Hong Kong，CUHK) 威爾斯親王醫院(Prince of Wales Hospital) -- 顳骨手術進修 (200709)
美國哈佛醫學院附屬麻州總醫院(Massachusetts general hospital, MGH) -- 頭頸癌課程進修 (201004)

學會及期刊：

台灣耳鼻喉頭頸外科醫學會專科醫師
美國耳鼻喉頭頸外科學院(AAOHNS)會員醫師
美國國家外科學院院士(FACS)
台灣頭頸部腫瘤醫學會專科醫師
台灣音聲醫學會專科醫師
亞洲頭頸部腫瘤醫學會醫師
醫學期刊 Invited Reviewer: BMC Cancer (SCI, IF:3.265); BioMed Research International (SCI, IF:2.583)

論文及著作：

1.     Publications:
First author
International Publication:
1.     Lai CC, Friedman M, Lin HC*, Wang PC, Hwang MS, Hsu CM, Lin MC, Chin CH. Clinical Predictors of Effective Continuous Positive Airway Pressure in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome. Laryngoscope. 2015; 125(8): 1983-1987.（SCI；IF=2.144；Otorhinolaryngology 7/43）
2.     Lai CC, Lin PM, Lin SF, Hsu CS, Lin HC, Hu ML, Hsu CM*, Yang MY*. Altered expression of SIRT gene family in head and neck squamous cell carcinoma. Tumour Biology 2013;34: 1847-1854.（SCI；IF=2.84；Oncology 93/202）
3.     Lai CC, Friedman M, Lin HC*, Wang PC, Hsu CM, Yalamanchali S, Lin MC, Chen YC. Objective versus Subjective Measurements of Palatine Tonsil Size in Adult Patients with Obstructive Sleep Apnea/Hypopnea Syndrome. Eur Arch Otorhinolaryngol 2014; 271(8):2305-2310.（SCI；IF=1.545；Otorhinolaryngology 13/43）
4.     Lai CC, Su CY*, Free mucosa graft from the lateral tongue for reconstruction of intraoral buccal/lip mucosal defects after tumor resection. Laryngoscope 2007; 117(8): 1368-1372.（SCI；IF=1.801；Otorhinolaryngology 5/30）
5.  Lai CC, Lin PW, Lin HC*, Friedman M, Chang HW, Salapatas AM, Lin MC, Wang PC. Clinical Predictors of Pediatric Obstructive Sleep Apnea Syndrome. Ann Otol Rhinol Laryngol 2018; 127(9): 608–613.（SCI；IF=1.384；Otorhinolaryngology 21/42）
6.  Lai CC, Lin PW, Lin HC, Friedman M, Chang HW, Salapatas AM, Lin MC, Huang KT. Effects of Upper Airway Surgery on Daytime Sleepiness in Nonobese Patients with Obstructive Sleep Apnea/Hypopnea Syndrome. Ann Otol Rhinol Laryngol 2018;127(12): 912-918.（SCI；IF=1.384；Otorhinolaryngology 21/42）

Co-author
International Publication:
1.     Su CY*, Lai CC, Wu PY, Huang HH. Transoral laser ventricular fold resection and thyroarytenoid myoneurectomy for adductor spasmodic dysphonia: long-term outcome. Laryngoscope 2010; 120(2): 313-318.（SCI；IF=2.1；Otorhinolaryngology 6/41）
2.     Hsu CM, Lin PM, Lai CC, Lin HS, Lin SF, Yang MY*. PER1 and CLOCK: Potential circulating biomarkers for head and neck squamous cell carcinoma. Head Neck 2014; 36(7):1018-26.（SCI；IF=2.641；Otorhinolaryngology 4/43）
3.     Lin HC*, Friedman M, Chang HW, Lai CC, Chin CH, Lin MC, Pott T, Samuelson C. Effects of Pillar implants for sleep-related breathing disorders on middle ear function. Eur Arch Otorhinolaryngol 2013; 270(8):2339-2343.（SCI；IF=1.608；Otorhinolaryngology 13/43）
4.     Lu CT, Hsu CM, Lin PM, Lai CC, Lin HC, Yang CH, Hsiao HH, Liu YC, Lin HY, Lin SF, Yang MY*. The Potential of SIRT6 and SIRT7 as Circulating Markers for Head and Neck Squamous Cell Carcinoma. Anticancer Res 2014 Dec;34(12):7137-7143.（SCI；IF=1.826；Oncology 145/202）
5.     Hsu CM*, Hsu CH, Yang MY, Lin HC, Lai CC, Hsu CY, Tsou YA. Glottal insufficiency with thyroid cartilage implantation: Our experience in eight patients. Clinical Otolaryngology 2012; 37(5):399-405.（SCI；IF=1.869；Otorhinolaryngology 9/43）
6.     Li SH, Lin WC, Huang TL, Chen CH, Chiu TJ, Fang FM, Huang WT, Hsu CM, Luo SD, Lai CC, Su YY, Chuang HC, Chien CY*. Significance of mTOR in patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil. Head Neck 2015; 38 Suppl 1:E844-52.（SCI；IF=2.641；Otorhinolaryngology 4/43）
7. Su YY, Chien CY, Luo SD, Huang TL, Lin WC, Fang FM, Chiu TJ, Chen YH, Lai CC, Hsu CM, Li SH*. Betel nut chewing history is an independent prognosticator for smoking patients with locally advanced stage IV head and neck squamous cell carcinoma receiving induction chemotherapy with docetaxel, cisplatin, and fluorouracil. World J Surg Oncol. 2016;14:86.（SCI；IF=1.6；Surgery 107/197）
8. Hsu CM, Lin PM, Lin HC, Lai CC, Yang CH, Lin SF, Yang MY. Altered Expression of Imprinted Genes in Squamous Cell Carcinoma of the Head and Neck. Anticancer Res. 2016 ;36(5):2251-8.（SCI；IF=1.937；Oncology 156/195）
9. Chou FF, Hsu CM, Lai CC, Chan YC, Chi SY*. Bilateral vocal cord palsy after total thyroidectomy–A new treatment–Case reports. Int J Surg Case Rep. 2017; 38: 32–36. 217/372.
10.   Lin HC, Lai CC, Lin PW, Friedman M, Salapatas AM, Chang HW, Lin MC, Chin CH. Clinical Prediction Model for Obstructive Sleep Apnea among Adult Patients with Habitual Snoring. Otolaryngol Head Neck Surg. 2019;161(1):178-185.（SCI；IF=2.310；Otorhinolaryngology 13/42）

11. Huang HH, Fang FM, Yang LN, Yang CH, Lai CC, Hwang CF*. A Longitudinal Hearing Analysis in Nasopharyngeal Carcinoma Patients with Middle Ear Effusion. J Taiwan Otoloaryngol Head Neck Surg Vol. 48, No.4, 2013 (臺灣耳鼻喉頭頸外科雜誌48卷4期2013) 258-264.

1.     Presentations:
Oral presentations:
a. Free mucosa graft of the tongue for reconstruction of buccal mucosa defect after resection of early buccal tumor. 77th meeting of TOHNS, 2004, Taipei
b. Surgical Technique and Outcome of Transoral CO2 Laser Treatment for Reinke’s Edema of Vocal Folds. 78th meeting of TOHNS, 2005, Kaoshiung
c. Transoral Laser Follicle Ablation for Hirsute Free Flaps in Oro-pharyngeal Reconstruction. 81th meeting of TOHNS, 2006, Taipei
d. Is It Possible to Cure the Adductor Spasmodic Dysphonia Using Laser Myoneurectomy of Thyroartenoid Muscles? 86th meeting of TOHNS, 2009, Kaoshiung
e. Objective vs Subjective Measurements of Palatine Tonsil Size in Patients with OSAHS. 89th meeting of TOHNS, 2010, Taipei
f. Optimal Predictor for Desaturation in Drug-induced Sleep Endoscopy. 93th meeting of TOHNS, 2012, Taipei
g. Minimally Invasive Single-Stage Multilevel Surgery for the Treatment of Obstructive Sleep Apnea/Hypopnea Syndrome. 97th meeting of TOHNS, 2014, Taipei
h. Midline Nasal Rosai–Dorfman Disease with Nasal Bone and Nasal Septal Involvement Undergoing Total Resection and Staged Reconstruction– Case Report and Literature Review. 13th Asia-Oceania ORL-HNS Congress, 2015, Taipei
i. Effect of Upper Airway Surgery in Non-obese Patients with OSA on Daytime Sleepiness. 101th meeting of TOHNS, 2016, Taoyuan

Poster presentations:
a. Epithelial-myoepithelial carcinoma of the parotid gland: a case report. 75th meeting of TOHNS, 2003, Tainan
b. Free Mucosa Graft from the Lateral Tongue for Reconstruction of Buccal Mucosa Defect Following Tumor Resection. (poster) XⅧ International Federation of Otorhinolaryngological Societies (IFOS) World Congress, Rome, Italy, June 25-30, 2005.
c. A huge carotid artery pseudoaneurysm after incision and drainage of deep neck infection - Case report. 89th meeting of TOHNS, 2010, Taipei
d. Juvenile Xanthogranuloma (JXG) with Systemic Involvement—Case Report. 93th meeting of TOHNS, 2012, Taipei
e. Longitudinal Analysis of Hearing Status in Nasopharyngeal Carcinoma Patients with Middle Ear Effusion. (IFOS 2013) 20th World Congress of the International Federation of Oto-Rhino-Laryngological Societies, Korea
f. Rhabdomyolysis-related deep neck infection. 95th meeting of TOHNS, 2013, Taipei
g. Dedifferentiated Carcinoma of the Supraglottis—Case Report. 102th meeting of TOHNS, 2017, Taitung
h. Pharyngeal extranodal nasal-type natural killer/T-cell lymphoma – Case Report and Literature Review. 103th meeting of TOHNS, 2017, Kaohsiung
i. Nasopharyngeal Papillary Adenocarcinoma – Case Report. 103th meeting of TOHNS, 2017, Kaohsiung; 14th Taiwan-Japan Conference, 2017, Kaohsiung
j. Computed Tomography-Guided Hook Wire Localization for Removal of Deep Neck Impacted Foreign Body—Case Report 105th meeting of TOHNS, 2018, Taipei

Research Project：
(1)「利用舌黏膜自由移植瓣重建口頰或唇黏膜腫瘤切除後之缺損」的前瞻性研究, 協同主持人, CMRPG860371, 2007/10/01至2008/09/30
(2)「以二氧化碳雷射毛囊汽化術治療口–咽部重建後之多毛自由皮瓣」的前瞻性研究, 協同主持人, 2008/10/01至2009/09/30
(3)「阻塞性睡眠呼吸中止症與平衡及前庭功能的相關性」的前瞻性研究, 主持人, CMRPG8D1261-1262, 2015/01/01至2017/10/31
(4)「闡述動力相關蛋白1在頭頸部鳞狀細胞癌癌化過程中所扮演的角色」的前瞻性研究, 協同主持人,
(5)「迴旋神經完整下，呼吸功能、發聲及吞嚥症狀在次發性副甲狀腺機能亢進病人手術切除後的變化」的前瞻性研究, 協同主持人

賴啟智 喉科

現職：

學經歷：

學會及期刊：

論文及著作：

賴啟智喉科