專業人才

邱志勇, M.D., Ph.D. 
單位: 基隆長庚紀念醫院暨情人湖院區
現職 : 兒科副教授級主治醫師
聯絡地址 : 204基隆市安樂區麥金路222號
電話 :+886-2-2431-3131 分機:2606
E-mail : pedchestic@gmail.com

研究領域:
  • Pulmonology 肺科
  • Pulmonary Airway Disease 肺氣管疾病
  • Respiratory Physiology and Mechanism 呼吸生理機制
  • Genomics and Molecular Biology基因組學與分子生物學
研究成果
  • The etiology causing asthma is complex with genetic and environmental factors. Many risk factors of asthma have been characterized based on epidemiological association studies. The innate mucosal immune system, represented by epithelial and other mucosal cells and their products, is able to recognize the conserved pathogenic patterns on microbes through pattern recognition receptors such as Toll-like receptors, CD14 and others. Interaction between the mucosal microbiota and immune cells is important in the development of the immune system. The microbiota mediates mechanisms of immunological tolerance and is essential in regulating mucosal inflammation. Modifications in microbiota patterns during infancy could alter the subsequent host immune responses, and might be essential in preventing mucosal inflammation. Microbiota in airway is hypothesized to play an important role in the development of allergic airway diseases. The central theme of my study is to understand the impact of alterations in airway microbiota patterns on the development of asthma.

工作經歷 :
  • 2013.04 - Present: Physician Scientist
  • 1995.07-1996.07: Internship, National Taiwan University Hospital, Taipei, Taiwan.
  • 1998.07-2001.07: Residentship, Department of Pediatrics, Chang Gung Children‘s Hospital, Taoyuan, Taiwan.
  • 2001.07-2002.07: Resident-in-chief, Department of Pediatrics Department of Pediatrics, Chang Gung Children‘s Hospital, Taoyuan, Taiwan.
  • 2001.07-2003.07: Fellowship, Division of Pulmonology, Department of Pediatrics, Chang Gung Children‘s Hospital, Taoyuan, Taiwan.
  • 2003.12: Attending Physician, Division of Pulmonology, Department of Pediatrics, Chang Gung Children‘s Hospital, Taoyuan, Taiwan.
  • 2004.01-Present: Attending Physician, Division of Pulmonology, Department of Pediatrics, Chang Gung Memorial Hospital, Keelung, Taiwan.

學歷 :
  • 1989-1996: Bachelor of Medicine, Chung Shan Medical University, Taichung, Taiwan.
  • 2008-2012: Doctor of Philosophy, Imperial College of Science, Technology and Medicine, London, UK

代表論文:
  1. Chih-Yung Chiu, Chan YL, Tsai YS, Chen SA, Wang CJ, Chen KF, Chung IF. Airway Microbial Diversity is Inversely Associated with Mite-Sensitized Rhinitis and Asthma in Early Childhood.Sci Rep. 2017 May 12;7(1):1820. doi: 10.1038/s41598-017-02067-7.
  2. Chih-Yung Chiu, Su SC, Fan WL, Lai SH, Tsai MH, Chen SH, Wong KS*, Chung WH*. Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption.Sci Rep. 2017 Feb 24;7:43469. doi: 10.1038/srep4346.(SCI; IF= 5.578; Multidisciplinary Sciences 5/56).
  3. Chih-Yung Chiu, Gigin Lin, Mei-Ling Cheng, Meng-Han Chiang, Ming-Han Tsai,Shen-Hao Lai, Kin-Sun Wong*, Sen-Yung Hsieh*. Metabolomic Profiling of Infectious Parapneumonic Effusions Reveals Biomarkers for Guiding Management of Childrenwith Streptococcus pneumoniae Pneumonia. Sci Rep. 2016 Apr 22;6:24930. doi: 10.1038/srep24930. (SCI; IF= 5.578; Multidisciplinary Sciences 5/56).
  4. Chih-Yung Chiu, Kuo-Wei Yeh, Gigin Lin, Meng-Han Chiang, Shu-Chen Yang, Wei-Ju Chao, Tsung-Chieh Yao, Ming-Han Tsai, Man-Chin Hua, Sui-Ling Liao, Shen-Hao Lai, Mei-Ling Cheng*, Jing-Long Huang*. Metabolomics Reveals Dynamic Metabolic Changes Associated with Age in Early Childhood.2016 Feb 25;11(2):e0149823. doi: 10.1371/journal.pone.0149823. eCollection 2016.(SCI; IF= 3.234; Multidisciplinary Sciences 8/56).
  5. Chih-Yung Chiu, Shih-Yin Huang, Yu-ChiehPeng, Ming-Han Tsai, Man-Chin Hua, Tsung-Chieh Yao, Kuo-Wei Yeh*, Jing-Long Huang*. Maternal vitamin D levels are inversely related to allergic sensitization and atopic diseases in early childhood. Pediatr Allergy Immunol. 2015 Jun; 26(4):337-43. doi: 10.1111/pai.12384. (SCI; IF=3.397; Pediatrics 9/119).

所有論文著作一覽表

殊榮:
  • Chih-Yung Chiu, Jing-Long Huang, Kin-Sun Wong, Ming-Han Tsai, Tzou-Yien Lin. Association of Proinflammatory Cytokines with Fibrinolytic Enzymes and Biochemical Parameters in Childhood Infectious Parapneumonic Effusions. Travel awards of  the 17th ECCMID / 25th ICC 2007 in Munich.