林政道 ,M.D.
單位: 林口長庚紀念醫院
現職: 婦癌科副教授級主治醫師
聯絡地址: 桃園市龜山區復興街五號
電話: 03-328-1200 分機:8255
E-mail: 51424@cgmh.org.tw
研究領域:
- Cytokine-based cancer immunotherapy 細胞因子為基礎的癌症免疫療法
- Immunochemoradiotherapy
- Biotherapy 生物治療
- Integrated cancer therapy in clinical application癌症臨床治療
研究成果
We administered subcutaneous route of immunomodulatory agents including of OK-432 (as adjuvant agent elicit CD83+ dendritic cells to perform phargocytosis, processing, and presenting) to recruit bodies’ immune cells, Interleukin-2 (as T cell growth factor), and interferon (as nature interferon producing cells’ product generate nature immunity). We used these drugs to elicit dendritic cells’ innate and adaptive immunity linkage to produce efficient cell-cell interaction of immunosynapse. Therefore, we final administrated oral or single agent chemotherapy drug and/ combination of chemotherapy to generate cancer cell death. Reference: Lin CT, Wang CN, Lai CH. Immunotherapy for advanced or relapsed cervical cancer. Gynecology and minimally invasive therapy 2013;2:3-7
工作經歷:
1999/11/01 – 2003/0/02/28 Investigator,
Pathology, immunology, Cellular and Molecular Biology Training Program at Johns Hopkins University School of Medicine Baltimore, MD USA (Wu, TC Professor)
2012 – Present associated Professor
Department of Obstetric& Gynecological of Gynecological cancer ,
Chang Gung medicine , Kweishan, Taiwan
學歷:
長庚大學學士後醫學系
美國約翰霍普金斯醫院大學病理科婦癌疫苗研發研究員
代表論文:
1. Lin CT, Qiu JT, Wang CJ, Chang SD, Tang YH, Wu PJ, Jung SM, Huang CC, Chou HH,
Jao MS, Lai CH. Topical imiquimod treatment for human papillomavirus infection in patients with
and without cervical/vaginal intraepithelial neoplasia. Taiwan J Obstet Gynecol. 2012 Dec;51(4):533-8. doi: 10.1016/j.tjog.2012.09.006.
2. I-Ju Chen, Chih-Feng Yen, Kun-Ju Lin, Chyi-Long Lee, Yung-Kuei Soong, Chyong-Huey lai, Cheng-Tao Lin (Corresponding author)Vaccination with OK-432 followed by TC-1 tumor lysate leads to significant antitumor effects Reproductive Sci 2011; Jul;18(7):687-94. doi: 10.1177/1933719110396230. Epub 2011 Feb 14.
3. Chang-Tao Lin, Chih-Feng Yen, Sheng-Wen Shaw, Tzu-Chen Yen, Yin-Ju Chen, Yung-Kuei Soong, Chyong-Huey Lai. Gene gun administration of therapeutic HPV DNA vaccination restore the efficacy of prolonged defrosted viral based vaccine. Vaccine. 2009 Sep 23. [Epub ahead of print]
4. Lin CT, Tsai YC, He L, Yeh CN, Chang TC, Soong YK, Monie A, Hung CF, Lai CH. DNA vaccines encoding IL-2 linked to HPV-16 E7 antigen generate enhanced E7-specific CTL responses and antitumor activity. Immunol Lett. 2007 Dec 15;114(2):86-93. Epub 2007 Oct 16.
5. Lin CT, Chang TC, Shaw SW, Cheng PJ, Huang CT, Chao A, Soong YK, Lai CH.
Maintenance of CD8 effector T cells by CD4 helper T cells eradicates growing
tumors and promotes long-term tumor immunity. Vaccine. 2006 Sep 11;24(37-39):6199-207. Epub 2006 Jun 23.
所有論文著作一覽表
學會與認證: Board Certification :
Registered Physician, since 1993
Administration of Medicine
Taiwan, Republic of China
License No. 26714
Licensers:
Specialty Board of Obstetrics and Gynecology, since 1997
Department of Obstetrics and Gynecology
License No. 002172
Professional Affiliations:
The Gynecology and Oncology of Taiwan
Laparoscopic minimal invasive surgery
The Society of Biology therapy (iSBT) of America USA NIH NCI since 2003
Professional National Board Examination and Medical Technique: 1983; License: No.3336
Professional Activities:
Gynecology and Oncology and tumor immunity of Taiwan Society
殊榮: 2004 - 9th Annual meeting Taiwan international society for medical oncology cancer for 2004. Recombinant Vaccinia increases HPV-16 E7-expressing Sindbis Virus replicon Particles (2004 Annual Taiwan cancer oncology Gynecology excellent poster paper award)
2006 - Annual promising research transfer technique award. Chung Gung Memorial hospital & University 2006