專業人才

林俊彥 , M.D.,Ph.D.
單位: 林口長庚紀念醫院 / 長庚大學
現職:
  • 長庚紀念醫院 林口醫學中心
    • 內科部 部主任
    • 胃腸肝膽科系主治醫師
  • 長庚大學 教授
  • 台灣消化醫學會 監事
  • 台灣肝癌醫學會 監事
  • 台灣超音波醫學會 常務理事

聯絡地址: 333桃園縣龜山鄉復興街五號
電話:03-3281200 分機:8107 / 傳真：03-3272236
E-mail: chunyenlin@gmail.com

研究領域:
  • Cellular Immunology 細胞免疫學
  • Tumor Immunology 腫瘤免疫學
  • Viral immunology 病毒免疫學
  • Liver immunology 肝臟免疫學
團隊介紹



研究成果

Main interest is to bridge the basic study, translational study and clinical study based on an immunological foundation. The main research fields are listed below:

  1. Basic Studies: Immune mechanisms of immune regulation: using mice model to explore the suppression mechanisms of different regulatory immune cells, including regulatory T cells, tolerogenic dendritic cells; tumor-associated macrophage and MDSC
    2. A. Immune regulation in tumor immunotherapy: using mice model to develop strategies of tumor immunotherapy, especially to block the inhibition effect of immune regulation.
    B. Immune regulation in acute liver injury: using mice model to explore the immune derangement in acute liver injury and to develop possible treatment strategies
  2. Translational Studies: Immune regulation in chronic viral hepatitis, liver cirrhosis, acute liver failure and cancer: using human studies to understand the impact of immune regulation on the disease progression and treatment outcome. The aim is to develop effective immune therapy and to develop useful immunometer for predict the disease progression.
  3. Clinical studies: Disease characteristics and treatment responses for chronic hepatitis C, chronic hepatitis B, liver cirrhosis and hepatoma. An immunological concept is the main underlying reasoning to approach these diseases.

工作經歷:
  • 長庚紀念醫院 林口醫學中心 肝臟科 主任
  • 長庚大學醫學系副系主任
  • 長庚紀念醫院林口醫學中心 研究部 副部長
  • 台灣消化醫學會雜誌 副主編
  • 台灣消化醫學會秘書長
  • 台灣肝病研究會秘書長
    • 2009年 亞太消化系醫學週 秘書長
    • 2012年 亞太肝臟醫學會年會 副秘書長
    • 2016年 亞太肝臟醫學會單一主題醫學會 副秘書長
    • 2018年 亞太肝臟醫學會單一主題醫學會 秘書長

學歷:
  • 1980-1987 台北醫學大學 醫學系
  • 1997-2002 英國牛津大學 醫學博士

代表論文:
  1. Lin YC, Mahalingam J, Chiang JM, Su PJ, Chu YY, Lai HY, Fang JH, Huang CT, Chiu CT, Lin CY*. Activated but not resting regulatory T cells accumulated in tumor microenvironment and correlated with tumor progression in patients with colorectal cancer.
  2. Mahalingam J, Lin YC, Chiang JM, Su PJ, Chu YY, Lai HY, Fang JH, Huang CT, Chiu CT, Lin CY*. LAP+CD4+ T cells are suppressors accumulated in the tumor sites and associated with the progression of colorectal cancer.
  3. Chang LY, Lin YC, Kan CW, Hsu CY, Chu YY, Huang CT, Day YJ, Chen TC, Yeh CT, Lin CY*. The indispensable role of CCR5 for in vivo suppressor function of CD103+ effector/memory regulatory T cells.
  4. Chang LY, Lin YC, Mahalingam J, Huang CT, Chen TW, Kang CW, Peng WM, Chu YY, Chiang JM, Dutta A, Day YJ, Chen TC, Yeh CT, Lin CY*. Tumor-derived chemokine CCL5 enhances TGF-β mediated killing of CD8+ T cells in colon cancer by T regulatory cells.
  5. Liu HL, Hsieh HY, Lu LA, Kang CW, Wu MF, Lin CY*. Low-Pressure Pulsed Focused Ultrasound with Microbubbles Promotes an Anticancer Immunological Response.

所有論文著作一覽表