Expertise at Chang Gung System

Ji-Yih Chen ,M.D.
Institution: Chang-Gung Memorial Hospital, Lin-Kou, Taipei / Chang gung university
Position: Professor/ Attending Physician
Department: Section of Rheumatology, Allergy and Immunology, Department of Internal Medicine
Address: 5 Fu-Shin Street, Kwei-Shan, Taoyuan 333, Taiwan
Tel: +886-3-328-1200 ext:8815 Fax: +886-3-3288287
E-mail: jychen31@adm.cgmh.org.tw

Focus of Interest :
  • Genetic analysis of Systemic lupus erythematosus, Rheumatoid arthritis and Ankylosing Spondylitis in Taiwan
  • Functional characterization of Fcα,Fcγ and Fas Receptor and their association with autoimmune diseases
  • Genetic analysis of Cardiovascular diseases and ankylosing spondylitis and treatment response.
  • Immunological manifestations and profiles changes among Hepatitis C virus infection and rheumatic diseases
  • Genetic transcriptional regulation of osteoblast/osteoclast differentiation

Fulltime Employment:

Attending Physician, Section of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Chang-Gung Memorial Hospital, Lin-Kou, Taipei.

Education:

  1. China Medical, College b(M. D.) Taichung, Taiwan, R.O.C.
  2. 1997/10~1999/04: Fellow, Clinical Rheumatology and Immunology.University of Alabama at Birmingham USA (Lupus Special Grant Research Center).
  3. 1999/05~2000/10: Fellow, Developmental and Clinical Immunology.University of Alabama at Birmingham USA (Molecular genetic and cellular analysis on B cell development).

Selected Publications:
  1. Wang CM, Chang SW, Wu YJ, Lin JC, Ho HH, Chou TC, Yang B, Wu J, Chen JY (Correspondent) Genetic variations in Toll-like receptors (TLRs 3/7/8) are associated with systemic lupus erythematosus in a Taiwanese population. Sci Rep. 2014 Jan 21;4:379
  2. Wang CM, Ho HH, Chang SW, Wu YJ, Lin JC, Chang PY, Wu J, Chen JY (Correspondent). ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis. Arthritis Res Ther. 2012 May 25;14(3):R125(SCI)
  3. Chen JY, Lin CY, Wang CM, Lin YT, Kuo SN, Shiu CF, Chang SW, Wu J, Sheen IS. IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-α plus ribavirin therapy in Taiwanese chronic HCV infection. Genes Immun. 2011 Jun;12(4):300-9(SCI).
  4. Chen JY, Wang C-M, Ma CC, Luo SF, Edberg JC, Kimberly RP, Wu J Association of Transmembrane Polymorphism of Fcgamma2b (FCGR2B) with Systemic Lupus Erythematosus in Taiwanese. Arthritis Rheum 2006;54:3908-17
  5. Ho HH, Yeh SJ, Tsai WP, Wang CM, Chen JY (Correspondent). Paroxysmal Supraventricular Tachycardia and Wolff-Parkinson-White Syndrome in Ankylosing Spondylitis: A Large Cohort Observation Study and Literature Review. Semin Arthritis Rheum. 2012; 42:246-53(SCI).



Full Publication List

Honor and Awards :
Taiwan Immunology society lupus outstanding Award.

Board Certification / Professional Affiliations:
Formosan Medical Association
The Society of Internal Medicine, R.O.C.
Rheumatism Association, R.O.C.
Chinese Society of Immunology
The Taiwanese Osteoporosis Association