| Research topic | PI |
| (1) Establish a mouse model to investigate the eosinophil behavior and treatment of allergic rhinitis (2) The change of nasal nitric oxide level after functional endoscopic sinus surgery and its relationship to sinus mucosal biofilm |
Chia-Hsiang Fu |
| (1) The role of EGFR downstream Ras/Raf/MEK/ERK/c-fos pathway and alterations of cyclin D1 gene in the pathogenesis of Taiwanese oral squamous cell carcinoma. (National Science Council, Ministry of Science and Technology, Taiwan, R.O.C.) (2) To establish treatment strategies for lymph node metastasis and lymph node extracapsular spread in oral squamous cell carcinoma. (Chang Gung Memorial Hospital, Linkou) |
Shiang-Fu Huang |
| (1) (2010.04 - 2014.06) (Principal Investigator)
Identification of potential biomarkers and associated mechanisms for metastasizing capability and extracapsular spread of oral squamous cell carcinomas based on proteomics and transcriptomes profiles.
(2) (2012.10 - 2014.09) (Principal Investigator) Biosignatures – OSCC1. (3) (2013.05 - 2015.04) (Principal Investigator) Systemic study of association between epithelial-mesenchymal transition (EMT) and genomic dysregulation in the metastatic genotype of oral cavity squamous cell carcinoma using an Affymetix Oncosan platform. (4) (2014.01-2016.12) EBV-NPC program: Biomarkers discovery for translational applications.(Sp1)Searching for genomic and proteomic markers for NPC susceptiblity and screening program. (Chief Principal Investigator and Principal Investigator of SP1) (5) (2014.01-2016.12)Application of point spectroscopy and high-resolution microendoscope in OSCC screening and post-treated monitoring. (6) (2013.08 - 2016.07) (Principal Investigator) Searching the detection and metastasis biomarkers in the body fluids and tissues from patients with oral cavity cancers based on the secretomic and tissue proteomic databases. |
Kai-Ping Chang |
| (1) PET-MRI as a treatment planning tool with radiation and chemotherapy for malignant brain tumors (2) A prospective observational study of late effects after proton radiotherapy for pediatric brain tumors of the brain, head and neck--- in comparison to that after photon radiotherapy |
Tsung-Ying Ho |
| (1) Investigation of the molecular links between liver inflammation and hepatocellular
carcinoma(HCC) on post hepatectomy patient survival: The activation of NfκB pathway and epithelial-mesenchymal transition of HCC cancer cell. (2) Crosstalk between dendritic cells,myeloid-dericed suppressor cell and regulatory T-cells and reversal of immunosuppression in murine hepatocellular carcinoma model |
Ting Jung Wu |
| Predictive biomarkers for prognosis in patients with resectable gastric carcinoma (1/2). ; from 2013/6/1 to 2014/5/31. | Jun-Te Hsu |
| (1) A novel biodegradable micelle bridging network system for extended delivery of diclofenac for retinal edema ( 2013/01-2014/07) (2) Clinical Validation of Non-invasive Hemoglobin Monitor (NIHbM) ( 2013/07-2014/06) | Yih-Shiou Hwang |
| (1) Host Factors and Disease Severity of Influenza Virus Infection: The Impact of Self-Antigen Mimicry and T cell repertoire
101/06~103/04 (2) An Investigation into the Significance of Host Factors for Disease Manifestations of Influenza Virus Infection: Cross Reactive Antigen, T Cell Repertoire and Cytokine Environment 102/08~103/07 (3) Mechanisms of controlled inflammation by antigen-specific CD4+ T cells in a transgenic mouse model of influenza 103/01~05/12 |
Ching-Tai Huang |
| (1) Study the intracellular inhibited signaling controlled on human CD4+ T lymphocytes in the patients of perennial allergic rhinitis treatment by mixed formula of Chinese medicine. (2) Study the effects of Chinese herbal medicine on chronic urticaria: a randomized, double-blind, placebo-controlled clinical trial. (3) Construction of cancer diseases in the integrated treatment of both traditional Chinese medicine and Western medicine cooperation in the conventional ward treatment and efficacy evaluation |
Sien-Hung Yang |
| (1) Establishing a GLP-compliant and certified laboratory for preclinical imaging studies. (2) Role of FDG-PET for Early Detection of Residual/Relapse Disease in Oral Cavity Cancer Patients at the Interval of after Radical Surgery and before Adjuvant Therapy. (3) Automatic detection and characterization of residual masses in patients with lymphomas through fusion of whole-body diffusion-weighted MRI on 3T and 18F-fluorodeoxyglucose. (4) Phase II study of [18F] RGD-K5 in Head and Neck Cancer Patients. (5) Phase II study of [18F]AV-45 PET amyloid binding imaging for patients with mild cognitive impartment, Alzheimer’s disease and healthy volunteers. |
Tzu-Chen Yen |
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