Expertise at Chang Gung System

Chen, Jan-Kan ,Ph.D.
Institution: Linkou Chang gung university
Position: Professor
Department: Physiology and Pharmacology
Address: Chang Gung University, 259 Wen-Hwa 1st Road, Kwei-Shan, TaoYuan, Taiwan, ROC 333 Department of Physiology (生理科)
Tel: +886-3-2118800 #5077 Fax: +886-3-2118239
E-mail: jkc508@mail.cgu.edu.tw

Focus of Interest:
  • Physiology
  • Stem cell
  • Tissue Engineering
  • Eneral Biology
  • Cell Biology
  • Signaling regulation in cancer cells

Education:
  • National Taiwan Normal University B. S. 1964/09~1968/06 Biology
  • National Taiwan University M.S. 1969/09~1972/05 Botany; Mycology
  • Boston College (USA) Ph.D. 1975/09~1979/06 Biology; Biochemistry

Honors and Awards:
  • Chang Gung University Dept. Physiology Professor 1993/07 ~ present
  • Chang Gung University Dept. Physiology Assoc. Professor 1989/07~1993/06
  • Organogenesis Inc. (Boston, USA) Vascular Cell Biology Senior Scientist and Group Head 1988/02~1989/07
  • W. Alton Jones Cell Science Center (Lake Placid, USA) Growth Factor Laboratory Senior Scientist 1986/07~1988/02
  • W. Alton Jones Cell Science Center Growth Factor Laboratory Visiting Scientist 1983/09~1986/06
  • University of Massachusetts (Amherst, USA) Biochemistry Post Doctoral Fellow 1979/09~1983/06

Selected Main Publications:
  1. Tsai RJF., Li L. M. and Chen J. K.* (2000) Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells. New England J. Medicine 343:86-93.
  2. Chu W. K., Dai P. M., Li H. L., Chen J. K.* (2008) Transcriptional activity of the ΔNp63 promoter is regulated by STAT3. J. Biol. Chem. 283:7328-7337.
  3. Cheng C. C., Wang D. Y., Kao M. H., Chen J. K.* (2009) The growth-promoting effect of KGF on limbal epithelial cells is mediated by upregulation of △Np63α through the p38 pathway. J. Cell Sci.122:4473-4480.
  4. Jing Y. H., Chen K. H., Kuo P. C., Pao C. C., Chen J. K.* (2013) Neurodegeneration in streptozotocin-induced diabetic rats is attenuated by treatment with resveratrol. Neuroendocrinology. 98:116-127
  5. Chu W. K., Dai P. M., Li H. L., Pao C.C. Chen J. K.* (2013) Nanog expression is negatively regulated by protein kinase C activities in human cancer cell lines. Carcinogenesis. 34(7): 1497-1509


All Publications List

Board Certification:
  • Society for Free Radical Research-Asia」(SFRR-Asia) - Director 台灣自由基協會 理事