Expertise at Chang Gung System

Wu, Chung-Pu ,Ph.D.
Institution: Chang Gung University
Position: Assistant professor
Department: Department of Physiology and Pharmacology
Address: No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan City 333, Taiwan (R.O.C.)
Tel: +886-3-211-8800 ext. 3754
E-mail: wuchung@mail.cgu.edu.tw

Focus of Interest:
  • Biochemistry and Molecular Biology - Medicine
  • Oncology
  • Pharmacology and Toxicology

Fulltime Employment:
  • Post-doctoral research fellow, National Cancer Institute, National Institutes of Health, USA
  • Post-doctoral research fellow, National Health Research Institute, Taiwan

Education:
  • Ph.D, Pharmacology, University of Cambridge, UK

Selected Main Publications:
  1. C-P Wu*, S-H Hsiao, C-Y Su, S-Y Luo, Y-Q Li, Y-H Huang, C-H Hsieh and C-W Huang. Human ATP-Binding Cassette transporters ABCB1 and ABCG2 confer resistance to CUDC-101, a multi-acting inhibitor of histone deacetylase, epidermal growth factor receptor and human epidermal growth factor receptor 2. Biochemical Pharmacology (2014) Nov, 92: 567-576.
  2. C-P Wu*, S-H Hsiao, S-Y Luo, W-C Tuo, C-Y Su, Y-Q Li, Y-H Huang and C-H Hsieh. Overexpression of human ABCB1 in cancer cells leads to reduced activity of GSK461364, a specific inhibitor of polo-like kinase 1. Molecular Pharmaceutics. (2014) Oct, 11(10): 3727-36.
  3. C-P Wu*, S-H Hsiao, H-M Sim, S-Y Luo, W-C Tuo, H-W Cheng, Y-Q Li, Y-H Huang and SV Ambudkar. Human ABCB1 (P-glycoprotein) and ABCG2 mediate resistance to BI 2536, a potent and selective inhibitor of polo-like kinase 1. Biochemical Pharmacology (2013) Oct, 86(7): 904-913
  4. C-P Wu*, H-M Sim, Y-H Huang, Y-C Liu, S-H Hsiao, H-W Cheng, Y-Q Li, SV Ambudkar and S-C Hsu. Overexpression of ATP-Binding Cassette transporter ABCG2 as a potential mechanism of acquired resistance to vemurafenib in BRAF(V600E) mutant cancer cells. Biochemical Pharmacology (2013) Feb, 85(3): 325-334.
  5. C-H Hsieh, C-P Wu, H-T Lee, J-A Liang, C-Y Yu and Y-J Lin. NADPH oxidase subunit 4 mediates cycling hypoxia-promoted radiation resistance in Glioblastoma multiforme. Free Radical Biology and Medicine (2012) Aug, 53(4): 649-658.


All Publications List