Chiu, Ching-Chi , Ph.D.
Institution: Chang Gung Memorial Hospital / Chang gung university
Position: Postdoctoral fellow
Department: Neuroscience Research Center Address:No.5, Fusing St., Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.) 
Tel: +886-3-3281200-8898 
E-mail: ccchei178@gmail.com
Focus of Interest:- Biochemistry and Molecular Biology - Medicine
- Molecular & Cell Biology
- Neurosciences
Fulltime Employment: ◎ 2009-2010 Postdoctoral Fellow, Graduate Institute of Medical Biotechnology and Laboratory Science, Chang Gung University, Taiwan.
◎ 2011-2012 Postdoctoral Fellow, Cancer Molecular Diagnostics Laboratory, Chang Gung Memorial Hospital, Taiwan.
◎ 2012-present Postdoctoral Fellow, Neuroscience Research Center, Chang Gung Memorial Hospital, Taiwan.
Education: 》09/2005-12/2009 Ph.D. Graduate Program in Molecular Biology and Biochemistry, Chang Gung University, Taiwan
》09/2003-06/2005 M.S. Graduate Institute of Medical Biotechnology and Laboratory Science, Chang Gung University, Taiwan
》09/1999-06/2003 B.S. Department of Medical Biotechnology, Chung Shan Medical University, Taiwan
Selected Main Publications:1.Glucose-regulated protein 78 regulates multiple malignant phenotypes in head and neck cancer and may serve as a molecular target of therapeutic intervention. Chiu CC, Lin CY, Lee LY, Chen YJ, Kuo TF, Chang JT, Liao CT, Wang HM, Yen TC, Shen CR, Liao SK, Cheng AJ. Mol Cancer Ther. 2008 Sep; 7(9):2788-97.
2.Molecular Chaperones as a Common Set of Proteins That Regulate the Invasion Phenotype of Head and Neck Cancer. Chiu CC, Lin CY, Lee LY, Chen YJ, Lu YC, Wang HM, Liao CT, Chang JT, Cheng AJ. Clin Cancer Res. 2011 Jul 15; 17(14):4629-41.
3.Grp78 as a therapeutic target for refractory head-neck cancer with CD24(-)CD44(+) stemness phenotype. Chiu CC, Lee LY, Li YC, Chen YJ, Lu YC, Li YL, Wang HM, Chang JT, Cheng AJ. Cancer Gene Ther. 2013 Nov;20(11):606-15.
4.The epigenetic factor Kmt2a/Mll1 regulates neural progenitor proliferation and neuronal and glial differentiation. Huang YC, Shih HY, Lin SJ, Chiu CC, Ma TL, Yeh TH, Cheng YC. Dev Neurobiol. 2014 Oct 3.
5.Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism. Chiu CC, Yeh TH, Lai SC, Wu-Chou YH, Chen CH, Mochly-Rosen D, Huang YC, Chen YJ, Chen CL, Chang YM, Wang HL, Lu CS. Exp Neurol. 2015 Jan;263:244-53.
Full Publication List
Patents:1.
English:Sequence complementary to Grp78 forms a special hair-pin structure inside cancer cells to specifically and effectively inhibit GRP78 expression and then inhibit the canceration process, including the growth, migration, invasion, and metastasis of cancer
Number:US7825100B2
Applicant:Ann-Joy Cheng, Joseph T. Chang, Ching-Chi Chiu
Inventor:Ann-Joy Cheng, Joseph T. Chang, Ching-Chi Chiu
Co-Inventor:Ann-Joy Cheng, Joseph T. Chang, Ching-Chi Chiu
Type:USA
2.
English:Specific GRP78 expression-inhibition RNAi sequence, medicine thereof and method thereof
Number:US7825100, US7829695, US20090181913, US20110008882
Applicant:Ann-Joy Cheng, Joseph T. Chang, Ching-Chi Chiu
Inventor:Ann-Joy Cheng, Joseph T. Chang, Ching-Chi Chiu
Co-Inventor:Ann-Joy Cheng, Joseph T. Chang, Ching-Chi Chiu