Expertise at Chang Gung System

Tzu-Chen Yen ,M.D.,Ph.D.
Intitution:
  • Director, Planning Center, Chang Gung Memorial Hospital
  • Director, Center for Academia and Industrial Collaboration, Chang Gung Memorial Hospital
  • Professor and Director, Center for Advanced Molecular Imaging and Translation , Chang Gung Memorial Hospital-Linkou
  • Professor, School of Medicine, Chang Gung University
Position: Director / Attending Physician / Professor
Department: Department of Nuclear Medicine
Mail Address: No.5, Fusing St., Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.)
Tel: +886-3-328-1200 ext.2673 Fax:+886 3 2110052
E-mail: yen1110@adm.cgmh.org.tw

Focus of Interest:
  • Medical Imaging
Education:
1991/06 Ph.D. Institute of Clinical Medicine, National Yang-Ming University, Taipei,

Fulltime Employment:
◎ 2012/6～Present   Director, Academia–Industry Collaboration Office, Chang Gung Memorial Hospital
◎ 2011/10～Present   Director, Planning Center, Chang Gung Memorial Hospital
◎ 2002/7～Present   Professor and Director, Center for Advanced Molecular Imaging and Translation, Chang Gung Medical Foundation
◎ 1997/2～Present   Associate Professor, Department of Medicine, School of Medicine, Chang Gung University

Selected Publications:
  1. Peng CH, Jiang YZ, Tai AS, Liu CB, Peng SC, Liao CT, Yen TC*, Hsieh WP. Causal inference of gene regulation with subnetwork assembly from genetical genomics data. Nucleic Acids Res. 2014;42:2803-19. correspondence
  2. Hsiao IT, Huang CC, Hsieh CJ, Wey SP, Kung MP, Yen TC*, Lin KJ. Perfusion-like template and standardized normalization-based brain image analysis using (18)F-florbetapir (AV-45/Amyvid) PET. Eur J Nucl Med Mol Imaging. 2013;40:908-20. correspondence
  3. Lu PL, Chen YC, Ou TW, Chen HH, Tsai HC, Wen CJ, Lo CL, Wey SP, Lin KJ, Yen TC*, Hsiue GH. Multifunctional hollow nanoparticles based on graft-diblock copolymers for doxorubicin delivery. Biomaterials. 2011;32:2213-21. co-correspondence
  4. Liu HL, Wai YY, Hsu PH, Lyu LA, Wu JS, Shen CR, Chen JC, Yen TC *, Wang JJ *. In vivo assessment of macrophage CNS infiltration during disruption of the blood-brain barrier with focused ultrasound: amagnetic resonance imaging study. J Cerebr Blood F Met. 2010;30:177-86. (SCI=5.398) correspondence
  5. Lin KJ*, Weng YH*, Wey SP, Hsiao IT, Lu CS, Skovronsky D, Chang HP, Kung MP, Yen TC*. Whole-body biodistribution and radiation dosimetry of 18F-FP-(+)-DTBZ (18F-AV-133) - a Novel vesicular monoamine transporter 2 imaging agent. J Nucl Med. 2010;51:1480-5. correspondence

Full Publication List

Honor and Awards:
 - 2012/05 國立陽明大學學術類傑出校友獎
 - 2012/12 Certiificate of Golden Award of 2012 National Biotechnology and Medical Care Quality Award

Board Certification / Professional Affiliations:
 (1) 中華民國核醫學學會委員 Society of Nuclear Medicine, Taiwan(R.O.C)
 (2) 行政院原子能委員會游離輻射安全諮詢會委員
 (3) 行政院原子能委員會衛生福利部食品藥物管理署醫療器材諮議委員
 (4) 財團法人醫藥品查驗中心(Center For Drug Evaluation) 業務指導顧問

Ongoing Projects：
  1. Establishing a GLP-compliant and certified laboratory for preclinical imaging studies.
  2. Role of FDG-PET for Early Detection of Residual/Relapse Disease in Oral Cavity Cancer Patients at the Interval of after Radical Surgery and before Adjuvant Therapy.
  3. Automatic detection and characterization of residual masses in patients with lymphomas through fusion of whole-body diffusion-weighted MRI on 3T and 18F-fluorodeoxyglucose.
  4. Phase II study of [18F] RGD-K5 in Head and Neck Cancer Patients.
  5. Phase II study of [18F]AV-45 PET amyloid binding imaging for patients with mild cognitive impartment, Alzheimer’s disease and healthy volunteers.