Expertise at Chang Gung System

Hsieh SY

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Sen-Yung Hsieh , M.D.,Ph.D.

Institution: Linkou Chang Gung Memorial Hospital / Chang Gung Uiversity

Position: Director /Physician/Professor

Department: Gastroenterology and Hepatology

Address: Dep. of Gastroenterology and Hepatology,No.5, Fusing St., Gueishan Township, Taoyuan County 333, Taiwan.

Tel: +886-3-3281200 ext.8128 Fax: +886-3-3272236

E-mail: siming@adm.cgmh.org.tw

Focus of Interest:

Oncology
Molecular and cell biology
Biochemistry and Molecular Biology - Medicine
Cancer Research
Gastroenterology&Hepatology
Molecular Biology
Microbiology
Molecular Biology

Fulltime Employment:

1982-83, Internship training, Veteran General Hospital, Taipei, Taiwan
1983-85, Medical officer during military service, Chinese Marine Corps, Kaohsiung, Taiwan
1985-87, Residency training in internal medicine, Provincial Taoyuan General Hospital, Taoyuan, Taiwan
1991-1992, Residency training in internal medicine, Chang Gung Memorial Hosp, Taipei, Taiwan
1992/8 to 1994/7, Research fellow in Hepatogastroenterology, Chang-Gung Mem Hosp, Taipei, Taiwan
1994/8 to 1996/7, Attneding doctor, Hepatogastroenterology, Chang-Gung Mem Hosp, Taipei, Taiwan
1996/7 to 1998/7, Associate professor in Internal Medicine, Chang Gung University School of Medicine
1993/8 to 2005/7, Associate professor in Microbiology and Immunology, Chang Gung University School
2005/8 to date, Professor, Microbiology and Immunology, Chang Gung University School of Medicine
Molecular Medicine Society of Taiwan, council member (2006/12 – 2011/01)
Taiwan Proteomics Society, council member (2008/01-2011/12)
Director, Clinical Proteomics Center, Chang Gung Memorial Hospital, Linkou, Taoyuan (2003/07-2016/06)
Director, Department of Medical Research, Chang Gung Memorial Hospital, Linkou, Taoyuan (2011/09-2016/06)
Director, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou, Taoyuan (since 2016/07- )

Education:

1983/6, M.D., National Yang-Ming Medical College, Taipei
Post-Graduate Education: 1991/7, Ph.D., Molecular biology/pathology, University of Pennsylvania, PA, U.S.A.

Honor and Awards:

1987 to 1991, government scholarship for PhD training in the US
1992, 1993, 1995, 1996, 1997, 1998, 2000 Research Award, National Science Council, Taiwan
1994, Outstanding Research Award, Professor JL Song’s Academic Foundation
1999, Outstanding Research Award, Taiwan Medical Association
2002, Outstanding Research Award, Japanese Society on Liver Study
2011, Best Paper Award, Japanese-American Association of Cancer Research Combined
2013, Best Teacher Award in Research, Chang Gung University
2018, Dr. Ta-Cheng Tung 's Basic Cancer Research Award

Selected Publications:

Hsieh SY*, He JR, Hsu CY, Chen WJ, Bera R, Lin KY, Shih TC, Yu MC, Lin YJ, Chang CJ, Weng WH, Huang HF.Neuregulin/Erythroblastic Leukemia Viral Oncogene Homolog 3 Autocrine Loop Contributes to invasion and Early Recurrence of Human Hepatoma. Hepatology. 53(2):504-516. FEB 2011. (* correspondent)
Shih TC, Tien YJ, Wen CJ, Yeh TS, Yu MC, Huang CH, Lee YS, Yen TZ, Hsieh SY*. MicroRNA-214 downregulation contributes to tumor angiogenesis by inducing secretion of the hepatoma-derived growth factor in human hepatoma. J Hepatology. 57(3):584-591. SEP 2012. (* correspondent)
Lo SL, Fan LC, Tsai YF, Lin KY, Huang HL, Wang TH, Liu H, Chen TC, Huang HF, Chang CJ, Lin YJ, Yung BY, Hsieh SY*. A novel interaction of nucleophosmin with BCL2-Associated X protein regulating deathevasion and drug sensitivity in humanhepatoma cells. Hepatology. 57(5):1893-1905. MAY 2013. (* correspondent)
Rabindranath Bera,* Chih-Yung Chiou,* Ming-Chin Yu, Jei-Ming Peng, Chung-Ru He, Chih-Yun Hsu, Hsiao-Ling Huang, Uda Y. Ho, Shi-Ming Lin, Yu-Jr Lin, and Sen-Yung Hsieh**.Functional Genomics Identified a NovelProtein Tyrosine Phosphatase Receptor Type F-Mediated Growth Inhibition in Hepatocarcinogenesis. Hepatology. 59(6):2238-2250. JUN 2014. (** correspondent)
Peng JM, Bera R, Chiou CY, Ming-Chin Yu, Tse-Chin Chen, Chia-Wei Chen, Tsung-Rui Wang, Wan-Ling Chiang, Shin-Pei Chai, Yongkun Wei, Huamin Wang, Mien-Chie Hung, Hsieh SY*. Actin cytoskeleton remodeling drives epithelial-mesenchymal transition for hepatoma invasion and metastasis. Hepatology. 2017 Nov 23. doi: 10.1002/hep.29678. [Epub ahead of print] (* correspondent)

Full Publication List

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