Expertise at Chang Gung System

Chang, Yu-Sun ,Ph.D.
Institution: Chang Gung University
Position: Chair Professor
Department: Graduate Institute of Biomedical Sciences
Address: No.259, Wenhua 1st Rd., Guishan Dist., Taoyuan City 33302, Taiwan (R.O.C.)
Tel: +886-3-3281200 Fax: +886-3-3285056

Focus of Interest:
  • Microbiology
  • Oncology

Fulltime Employment:
  • 1994/08-1999/08 Professor, Department of Microbiology & Immunology, Chang Gung Univesity
  • 1999/09-2001/07 Professor and Chair, Graduate Institute of Basic Sciecnes, Chang Gung University
  • 1999/09- Professor, Graduate Institute of Biomedical Sciences, Chang Gung University
  • 2005/10- Director, Molecular Medicine Research Center, Chang Gung University

  • Ph.D. Microbiology, University of California at Davis, USA
  • Master Plant Biochemistry, Brigham Young University, USA
  • B.S. Botany, National Chung Hsing University

Honors and Awards:
  • 2002、2011 Distinguished Research Award, National Science Council, Taiwan
  • 2014 Distinguished Research Award, Ministry of Science and Technology, Taiwan
  • 2002, 2014 Research Award, Chang Gung University
  • 2012 Technology Award
  • 1996-2002 Excellency Research Award

Selected Main Publications:
  1. Chi-Neu Tsai, Chia-lung Tsai, Ka-Po Tse, Hwan-You Chang, and Yu-Sun Chang. 2002. The Epstein-Barr virus oncogene product latent membrane protein 1 induces DNA methyltransferases to down-regulate E-cadherin gene expression. PNAS 99: 10084-10089.
  2. Ka-Po Tse, Wen-Hui Su, Kai-Ping Chang, Ngan-Ming Tsang, Chia-Jung Yu, Petrus Tang, Lee-Chu See, Chuen Hsueh, Min-Lee Yang, Sheng-Po Hao, Hong-Yi Li, Ming-Hsi Wang, Li-Ping Liao, Lih-Chyang Chen, Sheue-Rong Lin, Yu-Sun Chang and Yin Yao Shugart. 2009. Genome-wide association study reveals multiple Nasopharyngeal Carcinoma-associated loci within the HLA region at Chromosome 6p21.3. American Journal of Human Genetics 85(2):194-20380. (Corresponding) (SCI)
  3. Hao-Ping Liu, Chia-Chun Chen, Chih-Ching Wu, Yi-Chuan Huang, Shu-Chen Liu, Ying Liang, Kai-Ping Chang, and Yu-Sun Chang. 2012. Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Interacts with FGD4 to Activate Cdc42 and Thereby Promote Migration of Nasopharyngeal Carcinoma Cells. PLoS Pathogens. 8 (5) : e1002690
  4. Lih-Chyang Chen, Li-Jie Wang, Nang-Ming Tsang, David M. Ojcius, Chia-Chun Chen, Chun-Nan OuYang, Chuen Hsueh, Ying Liang, Kai-Ping Chang, Chiu-Chin Chen, and Yu-Sun Chang. 2012. Tumor inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in nasopharyngeal carcinoma. EMBO Mol Med. Dec;4(12):1276-93.
  5. Shu-Chen Liu, Ngan-Ming Tsang, Wen-Che Chiang, Chuen Hsueh, Ying Liang, Jyh-Lyh Juang, Kai-Ping N. Chow, Kai-Ping Chang, Yu-Sun Chang. 2013. Leukemia inhibitory factor regulates p70S6K and DNA damage responses to promote progressiveness and radioresistance of nasopharyngeal carcinoma in humans and mice. J Clinical Investigation 123(12):5269-5283

All Publications List

Board Certification :
  • Member, International Association of Epstein-Barr Virus and Associated Diseases Governing Board 2008-2010, International Association of Epstein-Barr Virus and Associated Diseases
  • Member, Chang Gung Nasopharyngeal Carcinoma Biomarker Discovery Team in International Cancer Biomarker Discovery Consortium (organized by Fred Hutchinson Cancer Research Center)
  • Member, International NPC Working Team (organized by National Cancer Institute, USA)