Expertise at Chang Gung System

Li, Hsin-Pai ,Ph.D.
Institution: Chang Gung University
Position: Assistant Professor
Department: Department of Microbiology & Immunology Graduate Institute of Biomedical Sciences Molecular Medicine Research Center
Address: 259 Wen-Hwa 1st Road,Kwei-Shan,Tao-Yuan, Taiwan, 333, R.O.C
Tel: +886-3-3118800 #3593

Focus of Interest:
  • Virology/ Microbiology
  • Cancer Biology
  • Biochemistry & Molecular Biology

Fulltime Employment:
  • 2008 –Till now: Assistant Professor Chang Gung University Department of Microbiology & Immunology
  • 2003 – 2008: Research Faculty/ Assistant Professor Chang Gung Memorial Hospital Department of Medical Research  SARS Research Group: (2003-2004, SARS Antigen Core)
  • 1998 – 2003: Postdoctoral Researcher Chang Gung University Dr. Yu-Sun Chang’s Lab  Study the oncogenic effect of Epstein Barr virus oncoprotein LMP1  /Screening drug(s) to inhibit EBV replication
  • 1990 – 1992: Research Assistant National Taiwan University Hospital M.D. Ming-Yang Lai’s Lab  Examination of the p53 gene mutations in hepatocellular carcinoma (HCC) patients in Taiwan / Study the correlation of HCC and hepatitis B virus (HBV) infection

  • PhD. University of Southern California (USC, USA) Department of Microbiology & Immnuonology
  • B.S. National Chung-Hsing University (NCHU, Taiwan) Department of Soil Science

Honors and Awards:
  • 2014 Best Teacher Award CGU (Consulting)
  • 2012 Best Teacher Award CGU (Teaching)

Selected Main Publications:
  1. Hsin-Pai Li+*, Hsin-Yi Huang+, Yi-Ru Lai, Jing-Xuan Huang, Kai-Ping Chang, Chuen Hsueh and Yu-Sun Chang (+Co-first author; *Corresponding) Silencing of miRNA-148a by hypermethylation activates the integrin-mediated signaling pathway in nasopharyngeal carcinoma Oncotarget 2014; (5)17:7610-24
  2. Hsin-Pai Li*+, Chen-Ching Peng+, I-Che Chung, Mei-Yuan Huang, Shao-Tung Huang, Chia-Chun Chen, Kai-Ping Chang, Cheng-Lung Hsu, Yu-Sun Chang (+Co-first author; *Corresponding) Aberrantly Hypermethylated Transcription Repressor Homeobox A2 Derepresses Metalloproteinase-9 Activity Through TBP and Promotes Invasion in Nasopharyngeal Carcinoma Oncotarget 2013; 4: 2154-2165
  3. Chia-Lung Tsai+, Hsin-Pai Li+, Chuen Hsueh, Ying Liang, Chi-Long Chen, Sai Wah Tsao, Ka-Po Tse, Yen-Jung Lu, Jau-Song Yu and Yu-Sun Chang (+ Co-first author) Activation of DNA methyltransferase 1 by Epstein-Barr Virus LMP1 involves JNK signaling. Cancer Research 2006; 66:11668-11674.
  4. Li HP, Leu YW, Chang YS. Epigenetic changes in virus-associated human cancers Cell Research 2005 Apr; 15(4):262-271
  5. Li HP, Zhang X, Duncan R, Comai L, Lai MM. Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription-regulatory region of mouse hepatitis virus RNA. Proc Natl Acad Sci U S A 1997 Sep 2;94(18):9544-9

All Publications List