Expertise at Chang Gung System

Lai, Chih-Ho , Ph.D
Intitution: Chang Gung university
Position: Professor/Research Fellow
  - Department of Microbiology and Immunology, Chang Gung University
  - Graduate Institute of Biomedical Sciences, Chang Gung University
  - Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital
Address: 259 Wen-Hwa 1st Road, Kwei-Shan, Taoyuan 33302, Taiwan
Tel: +886-3-2118800 ext. 5116 Fax: +886-3-2118700

Focus of Interest:
  • Biochemistry and Molecular Biology – Medicine
  • Immunology
  • Infectious Diseases
  • Microbiology

Fulltime Employment:
  • 2015Professor,Department of Microbiology and Immunology, Chang Gung University
  • 2013Professor,Department of Microbiology,School of Medicine, China Medical University
  • 2011 Assistant Professor, Department of Urology, The University of Texas Southwestern Medical Center
  • 2009 Associate Professor,Department of Microbiology,School of Medicine, China Medical University
  • 2006 Assistant Professor,Department of Microbiology, School of Medicine, China Medical University

  • 2005 Ph.D., Department of Life Science, National Tsing Hua University

Selected Main Publications:
  1. Lin HJ, Hsu FY, Chen WW, Lee CH, Lin YJ, Chen YY,Chen CJ, Huang MZ, Kao MC, Chen YA, Lai HC,Lai CH*.Helicobacter pylori activates HMGB1 expression and recruits RAGE into lipid rafts to promote inflammation in gastric epithelial cells. Front Immunol. 2016;7:1-11. (PMID: 27667993).
  2. Hung CL, Cheng HH, Hsieh WC, Tsai ZT, Tsai HK, Chu CH, Hsieh WP, Chen YF, Tsou Y, Lai CH*, Wang WC. The CrdRS two-component system in Helicobacter pylori responds to nitrosative stress. Mol Microbiol. 2015;97:1128-41. (PMID: 26082024).
  3. Lin CD, Kou YY, Liao CY, Li CH, Huang SP, Cheng YM, Liao WC, Wu PL, Kang JJ, Lee CC, Lai CH*. Zinc oxide nanoparticles impair bacterial clearance by macrophages. Nanomedicine. 2014;9:1327–1339. (PMID: 24628689).
  4. Lai CH*, Chang CS, Liu HH, Tsai YS, Yu YL, Lai CK, Gandee L, Pong RC, Hsu HW, Yu L, Saha D, and Hsieh JT. Sensitization of radio-resistant prostate cancer cells with a unique cytolethal distending toxin. Oncotarget. 2014;5:5523-5534. (PMID: 25015118).
  5. Lu DY,Chen HC, Yang MS, Hsu YM,Lin HJ, Tang CH, Lee CH, Lai CK, Lin CJ, Lai CH*. Ceramide and TLR4 are mobilized into membrane rafts in response to Helicobacter pylori infection in gastric epithelial cells. Infect Immun 2012;80:1823-33. (PMID: 22354030).

Full Publication List